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Topic: Polycythemia


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  Polycythemia -- Facts, Info, and Encyclopedia article   (Site not responding. Last check: 2007-10-22)
Polycythemia is a condition in which there is a net increase in the total circulating (A mature blood cell that contains hemoglobin to carry oxygen to the bodily tissues; a biconcave disc that has no nucleus) erythrocyte (red blood cell) mass of the body.
In primary polycythemia there may be 8 to 9 million and occasionally 11 million erythrocytes per cubic millimeter of blood, and the (A measuring instrument to determine (usually by centrifugation) the relative amounts of corpuscles and plasma in the blood) hematocrit may be as high as 70 to 80%.
Relative polycythemia is an apparent rise of the erythrocyte level in the blood; however, the underlying cause is reduced blood plasma.
www.absoluteastronomy.com /encyclopedia/p/po/polycythemia.htm   (760 words)

  
 Polycythemia - Wikipedia, the free encyclopedia
Polycythemia is a condition in which there is a net increase in the total circulating erythrocyte (red blood cell) mass of the body.
In primary polycythemia there may be 8 to 9 million and occasionally 11 million erythrocytes per cubic millimeter of blood, and the hematocrit may be as high as 70 to 80%.
Chemotherapy for polycythemia may be used sparingly, when the rate of bloodlettings required to maintain normal hematocrit is not acceptable.
en.wikipedia.org /wiki/Polycythemia   (718 words)

  
 Society : - Leukemia
Secondary polycythemia is caused by lower blood oxygen saturation, which might occur at high altitudes, with certain heart and lung diseases, or from an abnormal increase in the secretion of erythropoietin, a hormone that stimulates marrow to make red cells.
Polycythemia vera is called a clonal disorder because it begins with a change to the DNA in a single cell: all the cells that will dominate blood cell production are the offspring of the one mutant cell.
Polycythemia vera is a chronic disease; it is not curable.
www.leukemia-lymphoma.org /all_mat_toc.adp?item_id=9955   (1967 words)

  
 Polycythemia vera: myths, mechanisms, and management -- Spivak 100 (13): 4272 -- Blood   (Site not responding. Last check: 2007-10-22)
Polycythemia vera is a clonal disorder arising in a multipotent hematopoietic progenitor cell that causes the accumulation
The pathogenesis of polycythemia vera: polycythemia vera is a myeloaccumulative disorder not a myeloproliferative disorder
for the diagnosis of polycythemia vera and the diagnosis of acute
www.bloodjournal.org /cgi/content/full/100/13/4272   (8300 words)

  
 Myeloproliferative Disorders: PV FAQ
Polycythemia vera is one of the myeloproliferative disorders (MPD).
Polycythemia Vera is primarily a disease of middle-aged or elderly patients but we are seeing young patients as well In a retrospective study of 1231 PV patients followed for 20 years, the largest cluster of PV patients were found in the 41 to 80 age groups with the highest numbers in the 51-75 age groups.
Polycythemia vera (PV is the only myeloproliferative disease in which involvement of the erythrocytes (red cells) results in an increased red cell mass.
www.acor.org /mpd/PVFAQ.html   (4471 words)

  
 Lancaster General Hospital - Polycythemia Vera   (Site not responding. Last check: 2007-10-22)
Polycythemia vera is a rare blood disorder in which there is an increase in all blood cells, particularly red blood cells.
Polycythemia vera is one type of myeloproliferative disorder (MPD).
In polycythemia vera, there may be an increase in just the red blood cells, both the red and white blood cells, or in the red and white blood cells and platelets.
www.lancastergeneral.org /content/greystone_20444.asp   (301 words)

  
 THE MERCK MANUAL--SECOND HOME EDITION, Polycythemia Vera in Ch. 178, Myeloproliferative Disorders
Polycythemia vera (primary polycythemia) is a disorder of the blood-producing cells of the bone marrow that results in overproduction of red blood cells.
Polycythemia vera may be discovered through routine blood tests performed for another reason, even before a person has any symptoms.
Secondary and relative polycythemia differ from polycythemia vera (which literally translates as “true polycythemia”) in that their causes are known.
www.merck.com /mmhe/ag/sec14/ch178/ch178b.html   (1048 words)

  
 Polycythemia Vera, Blood Disorders, THE MERCK MANUAL OF HEALTH & AGING
The cause of polycythemia vera is, by definition, unknown.
Polycythemia may be diagnosed during routine blood tests, even before a person has any symptoms.
Once polycythemia is diagnosed, doctors determine whether the disorder is polycythemia vera or secondary polycythemia.
www.merck.com /pubs/mmanual_ha/sec3/ch49/ch49f.html   (769 words)

  
 Secondary Polycythemia | aHealthyAdvantage   (Site not responding. Last check: 2007-10-22)
Secondary polycythemia is an acquired form of a rare disorder characterized by an abnormal increase in the number of mature red cells in the blood.
Known as spurious polycythemia, stress polycythemia, or Gaisbock's syndrome, relative polycythemia is characterized by normal numbers of red blood cells but decreased levels of plasma (the fluid part of the blood).
Unlike secondary polycythemia, primary polycythemia cannot be traced to an underlying condition such as smoking, high altitude, or chronic lung disease.
www.ahealthyadvantage.com /topic/topic100587450   (668 words)

  
 AllRefer.com - polycythemia (Pathology) - Encyclopedia
Primary polycythemia, also called erythremia, or polycythemia vera, is a chronic, progressive disease, most common in middle-aged men.
Primary polycythemia is treated by radiation, periodic removal of some blood (phlebotomy), or chemotherapy with antimetabolite drugs, e.g., Cytoxan.
In secondary polycythemia, or erythrocytosis, the proliferation of red blood cells results from the body's attempt to compensate for other conditions, such as prolonged lack of oxygen at high altitudes or chronic lung or heart insufficiency.
reference.allrefer.com /encyclopedia/P/polycyth.html   (250 words)

  
 Alaskabigdog's polycythemia and viagra   (Site not responding. Last check: 2007-10-22)
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www.alaskabigdog.com /polycythemia-and-viagra.html   (2010 words)

  
 Polycythemia Vera | AHealthyMe.com
Polycythemia vera (PV) is a chronic blood disorder marked by an abnormal increase in three types of blood cells produced by bone marrow: red blood cells (RBCs), white blood cells (WBCs), and platelets.
Polycythemia vera is a relatively common progressive disorder that develops over a course of 10-20 years.
Primary polycythemia means that the disorder is not caused or triggered by other illnesses.
www.ahealthyme.com /topic/topic100587319   (1681 words)

  
 Information about Polycythemia Vera
Polycythemia Vera is a condition that occurs when the bone marrow produces too many blood cells.
In polycythemia vera, there is a high concentration of red blood cells, granulocytes, and platelets.
The exact cause of polycythemia vera is unknown.
www.mamashealth.com /blood/polyv.asp   (176 words)

  
 Polycythemia Vera
It is possible that the main title of the report Polycythemia Vera is not the name you expected.
Polycythemia vera is a rare, chronic disorder involving an overproduction of blood cells in the bone marrow (myeloproliferative).
The exact cause of polycythemia vera is not known.
my.webmd.com /hw/health_guide_atoz/nord236.asp   (483 words)

  
 Merck Vet. Edition - Polycythemia: Introduction
Polycythemia is a relative or absolute increase in the number of circulating RBC.
Primary polycythemia, or polycythemia rubra vera, is a myeloproliferative disease of unknown cause.
Blood gas determination is abnormal in secondary polycythemia due to pulmonary disease or right-to-left shunting.
www.merckvetmanual.com /mvm/htm/bc/10900.htm   (459 words)

  
 eMedicine - Polycythemia : Article by Kristin Baird, MD   (Site not responding. Last check: 2007-10-22)
Primary polycythemias are due to factors intrinsic to red cell precursors and include the diagnoses of primary familial and congenital polycythemia (PFCP) and polycythemia vera (PV).
Primary polycythemia - Although the pathophysiology is unclear, primary polycythemias are thought to be due to inherited and acquired mutations in erythroid progenitors leading to abnormal red cell proliferation.
Primary polycythemia: The goals of therapy are to maximize survival while minimizing the complications of therapy as well as of the disease itself.
www.emedicine.com /ped/topic1848.htm   (3144 words)

  
 Polycythemia Vera: The Natural History of 1213 Patients Followed for 20 Years -- Gruppo Italiano Studio Policitemia* ...
Frequencies of diagnosis of polycythemia vera according to age and sex.
Increased incidence of acute leukemia in polycythemia vera associated with chlorambucil therapy.
Increased thromboxane biosynthesis in patients with polycythemia vera: evidence for aspirin-suppressible platelet activation in vivo.
www.annals.org /cgi/content/full/123/9/656   (5048 words)

  
 Polycythemia
Polycythemia is a condition in which there are too many red blood cells in the blood circulation.
Twin-to-twin transfusion, when the shared placenta of the two babies has a connecting circulation and blood flows from one baby to the other, may result in polycythemia.
Laboratory tests show a high hematocrit (red blood cell count) when polycythemia is present.
www.healthsystem.virginia.edu /UVaHealth/peds_hrnewborn/polycyth.cfm   (444 words)

  
 THE MERCK MANUAL, Sec. 11, Ch. 130, Myeloproliferative Disorders
Polycythemia vera (PV) occurs in about 2.3/100,000 people per year; more often in males (about 1.4:1).
The mean age at diagnosis is 60 yr (range, 15 to 90 yr; rarely in childhood); 5% of patients are < 40 yr at onset.
In relative (spurious) erythrocytosis (ie, stress polycythemia, Gaisböck's syndrome), the RBC mass is normal and the elevated Hct is caused by a decreased plasma volume.
www.merck.com /pubs/mmanual/section11/chapter130/130b.htm   (1645 words)

  
 polycythemia   (Site not responding. Last check: 2007-10-22)
It is associated with several conditions in adulthood, but in children this condition is usually only diagnosed in the newborn.
Polycythemia can have deleterious effects, first because the blood can be literally too thick to pass easily through the small blood vessels of the body.
Most cases of neonatal polycythemia are asymptomatic, self-limited, harmless and not treated.
www.sleeptight.com /EncyMaster/P/polycythemia.html   (122 words)

  
 How is Polycythemia Rubra Vera Treated?
There are six diseases included in the group of myeloproliferative disorders and this group includes chronic....
There are diagnostic criteria set by Polycythemia Vera Study Group to make a......
Polycythemia rubra vera is a slowly progressive disease which may progress over a period of one to three years before it is brought to medical attention.
www.angelfire.com /ar3/mpd   (100 words)

  
 eMedicine - Polycythemia, Secondary : Article by Emmanuel C Besa, MD
In contrast, polycythemia vera is characterized by bone marrow with an inherent increased proliferative activity.
Chuvash polycythemia is caused by an autosomal recessive gene mutation on the von Hippel-Lindau gene, which results the upregulation of the HIF1-alpha target gene and causes elevations in EPO levels.
Distinguishing between polycythemia vera/primary polycythemia and secondary polycythemias is important because patients with untreated polycythemia vera have a very high risk of thrombotic problems and, to a lesser degree, hemorrhagic problems, which may be fatal or severely disabling.
www.emedicine.com /med/topic1863.htm   (2671 words)

  
 Polycythemia Support - Myeloproliferative Disorder   (Site not responding. Last check: 2007-10-22)
Primary polycythemia, often called polycythemia vera (PCV), polycythemia rubra vera (PRV), erythremia, or just PV, occurs when excess erythrocytes are produced as a result of tumorous abnormalities of the bone marrow.
Relative polycythemia (PVr) is an apparent raise of the erythrocyte level in the blood; however, the underlying cause is reduced plasma blood.
* Primary familial polycythemia: a frameshift mutation in the erythropoietin receptor gene and increased sensitivity of erythroid progenitors to erythropoietin.
racinnews.com /mpd.htm   (1089 words)

  
 Congenital disorder of oxygen sensing: association of the homozygous Chuvash polycythemia VHL mutation with thrombosis ...
Endemic polycythemia in Russia: mutation in the VHL gene.
Mutation in the VHL gene in sporadic apparently congenital polycythemia.
Pathogenetic mechanisms of polycythemia vera and congenital polycythemic disorders.
www.bloodjournal.org /cgi/content/full/103/10/3924   (5339 words)

  
 Polycythemia - Children's Hospital of Philadelphia
It is the opposite of anemia, which results from too few red blood cells in the blood circulation.
The following are the most common symptoms of polycythemia.
A high hemoglobin (protein in the blood that carries oxygen) level may also help diagnose polycythemia.
www.chop.edu /consumer/your_child/condition_section_index.jsp?id=-8748   (417 words)

  
 MedlinePlus Medical Encyclopedia: Polycythemia vera
Primary polycythemia; Polycythemia rubra vera; Myeloproliferative disorder; Erythremia; Splenomegalic polycythemia; Vaquez's disease; Osler's disease; Polycythemia with chronic cyanosis - Myelopathic polycythemia; Erythrocytosis megalosplenica; Cryptogenic polycythemia
The use of anti-platelet therapy (such as aspirin) is controversial because it may cause gastric bleeding.
Polycythemia vera usually develops slowly, and most patients treated appropriately do not experience any problems related to the disease.
www.nlm.nih.gov /medlineplus/ency/article/000589.htm   (583 words)

  
 Introduction: Polycythemia - WrongDiagnosis.com
Researching symptoms of Polycythemia: Further information about the symptoms of Polycythemia is available including a list of symptoms of Polycythemia, or alternatively return to research other symptoms in the symptom center.
Treatments for Polycythemia: Various information is available about treatments available for Polycythemia, or research treatments for other diseases.
Statistics and Polycythemia: Various sources and calculations are available in statistics about Polycythemia, and you can also research other medical statistics in our statistics center.
www.wrongdiagnosis.com /p/polycythemia/intro.htm   (195 words)

  
 A Polycythemia Vera Update: Diagnosis, Pathobiology, and Treatment -- Pearson et al. 2000 (1): 51 -- Hematology
Circulating erythroid progenitors in polycythemia vera are hypersensitive to insulinlike growth factor-1 in vitro: studies in an improved serum-free medium.
Increased basal and induced tyrosine phosphorylation of the insulin-like growth-factor-I receptor-beta subunit in circulating mononuclear-cells of patients with polycythemia-vera.
Treatment of polycythemia vera: the use of hydroxyurea and pipobroman in 292 patients under the age of 65 years.
www.asheducationbook.org /cgi/content/full/2000/1/51   (8005 words)

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