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Topic: Polymyxin

Related Topics

Colistin

Antibiotic

Quinolones

Linezolid

Tetracycline

Vancomycin

Meropenem

Polyketide

Ciprofloxacin

Sulfamethoxazole

Trimethoprim

Penicillin

Erythromycin

Quercus palustris

Azithromycin

	Polymyxin - Wikipedia, the free encyclopedia
		Polymyxins are cationic detergent antibiotics, with a general structure of a cyclic peptide with a long hydrophobic tail.
		Polymyxins have a bactericidal effect on Gram-negative bacilli, especially on pseudomonas and coliform organisms.
		Polymyxin antibiotics are highly neurotoxic and nephrotoxic, and very poorly absorbed from the gastrointestinal tract.
	en.wikipedia.org /wiki/Polymyxin (109 words)

	[No title] (Site not responding. Last check: 2007-10-13)
		Formation of a polymyxin B-terbium complex Polymyxin B pentasulfate (Sigma) (80 milligrams (mg), 0.05 millimoles (mmol)), was dissolved in 5 mL of 0.05 M acetate buffer, pH 5.5.
		The complex of claim 5 wherein the cyclic antibiotic is polymyxin B. The complex of claim 5 wherein the cyclic antibiotic is colistin.
		The method of claim 40 wherein the antibiotic is polymyxin B and the assay is a chemiluminescent assay.
	www.wipo.int /cgi-pct/guest/getbykey5?KEY=01/26673.020801&ELEMENT_SET=DECL (4384 words)

	polymyxin B and trimethoprim ophthalmic - [Medication] (Site not responding. Last check: 2007-10-13)
		The ophthalmic form of polymyxin B and trimethoprim is used to treat bacterial infections of the eyes.
		Polymyxin B and trimethoprim ophthalmic may also be used for purposes other than those listed in this medication guide.
		Polymyxin B and trimethoprim ophthalmic is available with a prescription under the brand name Polytrim Ophthalmic Solution.
	www.bcbswny.com /kbase/multum/d03529a1.htm (1031 words)

	[No title] (Site not responding. Last check: 2007-10-13)
		The polymyxins are toxic to coliform bacteria because these antibiotics bind to the LPS in the outer membrane envelope and disrupt cellular metabolism once translocated to the inner membrane cytoplasmic membrane.
		A chelated complex comprised of (a) an antibiotic selected from the group consisting of polymyxins, colistins, aminoglycosides, and analogs and fragments thereof, and (b) a detectable label comprising a metal selected from the group consisting of transition metals and lanthanides, wherein the complex is capable of binding to gram negative bacterial cells or residues thereof.
		The complex of claim 5, wherein the polymyxin or polymyxin fragment is selected from the group consisting of polymyxin A, B, C, D and E. The complex of claim 1, wherein the antibiotic is a colistin or an enzymatic or chemically derived fragment of colistin.
	www.wipo.int /cgi-pct/guest/getbykey5?KEY=01/27628.010419&ELEMENT_SET=DECL (6195 words)

	Cortisporin Online, Description, Chemistry, Ingredients - Hydrocortisone; Neomycin; Polymyxin B - RxList Monographs
		CORTISPORIN Cream (neomycin and polymyxin B sulfates and hydrocortisone acetate cream, USP) is a topical antibacterial cream.
		Each gram contains: neomycin sulfate equivalent to 3.5 mg neomycin base, polymyxin B sulfate equivalent to 10,000 polymyxin B units, and hydrocortisone acetate 5 mg (0.5%).
		Polymyxin B sulfate is the sulfate salt of polymyxin B
	www.rxlist.com /cgi/generic/neopolhc.htm (242 words)

	Buy Terramycin Antibiotic Ophthalmic Ointment with Polymyxin B Sulfate Online at drugstore.com
		Polymyxin B sulfate is one of a group of related antibiotics derived from Bacillus polymyxa.
		The broad-spectrum effectiveness of Terramycin against both gram-positive and gram-negative organisms is enhanced by the particular effectiveness of polymyxin B against infections associated with gram-negative organisms, especially those due to Pseudomonas aeruginosa were polymyxin B is the antibiotic of choice.
		Terramycin Ophthalmic Ointment with Polymyxin B Sulfate is a suspension of oxytetracycline hydrochloride and polymyxin B sulfate in a special petrolatum base.
	www.drugstore.com /qxp87550_332828_sespider/terramycin/antibiotic_ophthalmic_ointment_with_polymyxin_b_sulfate.htm (549 words)

	polymyxin B ophthalmic - [Medication]
		The ophthalmic form of polymyxin B is used to treat bacterial infections of the eyes.
		Polymyxin B ophthalmic may also be used for purposes other than those listed in this medication guide.
		Polymyxin B ophthalmic is in the FDA pregnancy category C. This means that it is not known whether polymyxin B ophthalmic will harm an unborn baby.
	www.peacehealth.org /kbase/multum/d04134a1.htm (970 words)

	USE OF POLYMYXIN B IMMOBILIZED FABRIC (PMX-D) FOR BURN WOUND DRESSING
		Antibiotic polymyxin B has strong antimicrobial activity and is known to bind endotoxin and neutralize it (1).
		Alpha-chroloacetoamidemethylated polystyrenebased knitted fabric was used as the carrier fabric to immobilize polymyxin B. The amount of fixed polymyxin B was measured by amino acid analysis.
		It was estimated that antibiotic polymyxin B was well fixed on the surface of the fibre in keeping with the antimicrobial activity of this agent.
	www.medbc.com /annals/review/vol_6/num_3/text/vol6n3p161.htm (794 words)

	MedlinePlus Drug Information: Neomycin, Polymyxin B, and Hydrocortisone (Otic) (Site not responding. Last check: 2007-10-13)
		Neomycin, polymyxin B, and hydrocortisone (nee-oh-MYE-sin, pol-i-MIX-in bee, and hye-droe-KOR-ti-sone) is a combination antibiotic and cortisone-like medicine.
		Children—Although there is no specific information comparing use of otic neomycin, polymyxin B, and hydrocortisone preparation in children with use in other age groups, this preparation is not expected to cause different side effects or problems in children than it does in adults.
		Although there is no specific information comparing use of otic neomycin, polymyxin B, and hydrocortisone preparation in the elderly with use in other age groups, this preparation is not expected to cause different side effects or problems in older people than it does in younger adults.
	www.nlm.nih.gov /medlineplus/druginfo/uspdi/202403.html (1038 words)

	MedlinePlus Drug Information: Neomycin, Polymyxin, and Bacitracin Ophthalmic
		Neomycin, polymyxin, and bacitracin combination is used to treat eye and eyelid infections.
		Neomycin, polymyxin, and bacitracin are in a class of medications called antibiotics.
		Neomycin, polymyxin, and bacitracin combination works by stopping the growth of bacteria infecting a surface of the eye.
	www.nlm.nih.gov /medlineplus/druginfo/medmaster/a604019.html (962 words)

	Contemporary Assessment of Antimicrobial Susceptibility Testing Methods for Polymyxin B and Colistin: Review of ...
		Polymyxins are a group of polycationic peptides naturally synthesized by Bacillus polymyxa, a nonactinomycete bacterium (7).
		Polymyxin B and colistin have been demonstrated to be active against Pseudomonas aeruginosa.
		Polymyxin B and colistin sulfate powders were obtained from Sigma Chemical (St. Louis, Mo.).
	jcm.asm.org /cgi/content/full/39/1/183 (3121 words)

	bacitracin and polymyxin B ophthalmic Drug Information
		The ophthalmic form of bacitracin and polymyxin B is used to treat bacterial infections of the eyes.
		It is not known whether bacitracin and polymyxin B ophthalmic will be harmful to an unborn baby.
		It is not known whether bacitracin and polymyxin B ophthalmic passes into breast milk.
	www.drugs.com /mtm/bacitracin_and_polymyxin_B_ophthalmic.html (1085 words)

	Neomycin and Polymyxin B (Topical) - MayoClinic.com (Site not responding. Last check: 2007-10-13)
		Neomycin and polymyxin B (nee-oh-MYE-sin and pol-i-MIX-in bee) combination is used to prevent bacterial infections.
		Neomycin and polymyxin B cream is applied to the skin to prevent minor bacterial skin infections.
		Although there is no specific information comparing use of neomycin and polymyxin B combination in children with use in other age groups, this medicine is not expected to cause different side effects or problems in children than it does in adults.
	www.mayoclinic.com /health/drug-information/DR202398 (841 words)

	The PmrA-Regulated pmrC Gene Mediates Phosphoethanolamine Modification of Lipid A and Polymyxin Resistance in ...
		Polymyxin B is a cyclic antimicrobial lipopeptide produced by
		lipid A (13) and for polymyxin B resistance (12, 13).
		Polymyxin B was added to a final concentration of 10 µg/ml, and the bacteria were incubated for 1 h at 37°C. The samples were diluted in PBS and plated on LB agar plates to determine the numbers of CFU.
	jb.asm.org /cgi/content/full/186/13/4124 (6425 words)

	[No title] (Site not responding. Last check: 2007-10-13)
		POLYMYXIN B is an antibiotic used for serious eye infections that do not respond to other antibiotics.
		Polymyxin B eye solution should only be used in the eye.
		If polymyxin B eye solution is used for a long period of time, serious side effects may develop.
	www.eckerd.com /RxAdvisor/showtext.asp?cpnum=496&match=F&infotype=&ixid=487&ix=PolymyxinBeyesolution&gname=PolymyxinB&last=〈=sp (590 words)

	DG DISPATCH - WCPGHN: Oral Polymyxin Not Effective For Infants With Severe/Persistent Diarrhea
		In an effort to evaluate clinical outcome as well as the effects of polymyxin on the jejeunal microflora of children with severe or persistent diarrhea, researchers conducted a seven-day, prospective, double-blind, randomized trial.
		In the polymyxin group, nine of 13 patients had EPEC at baseline, which was eradicated in all 13 patients by trial's end.
		Although polymyxin was highly effective in eradicating EPEC, the researchers concluded that oral polymyxin "was not effective in reducing bacterial overgrowth, [nor in] the clinical outcome of infants with severe acute or persistent diarrhea."
	www.docguide.com /dg.nsf/PrintPrint/0E7F8C4A0F5314818525693600512C86 (492 words)

	oxytetracycline and polymyxin B ophthalmic Drug Information
		The ophthalmic form of oxytetracycline and polymyxin B is used to treat bacterial infections of the eyes.
		Oxytetracycline and polymyxin B ophthalmic may also be used for purposes other than those listed in this medication guide.
		It is not known whether oxytetracycline and polymyxin B ophthalmic passes into breast milk.
	www.drugs.com /MTM/oxytetracycline_and_polymyxin_B_ophthalmic.html (1050 words)

	CDC - Polymyxin-Resistant Acinetobacter spp. Isolates: What is Next?
		The susceptibility to polymyxin B and meropenem were tested by disk diffusion and agar dilution techniques according to NCCLS recommendations (9,10).
		The susceptibility interpretative criteria for meropenem and polymyxin B were based on the current and former NCCLS documents, respectively (7,11).
		To evaluate whether the polymyxin B-resistant strains isolates were epidemiologically related, these isolates were molecularly typed by pulsed-field gel electrophoresis (PFGE) as previously described (12).
	www.cdc.gov /NCIDOD/EID/vol9no8/03-0052.htm (1140 words)

	Ray1 Polymyxin B Sulfate (Site not responding. Last check: 2007-10-13)
		Polymyxin B Sulfate is used in several everyday products.
		Polymyxin B Sulfate is found in a wide variety of health and wellness products, like neosporin, and other antibiotic ointments.
		Polymyxin B Sulfate when used in antibiotic ointment is used primarially on scrapes and cuts.
	www.cas.astate.edu /draganjac/Ray1.html (164 words)

	Neomycin and Polymyxin B Irrigant - Drugs & Vitamins - Drug Library - DrugDigest
		Neomycin; Polymyxin B is for continuous irrigation of your bladder.
		Neomycin; Polymyxin B bladder irrigation is usually given in a hospital by a health care professional.
		Neomycin; Polymyxin B bladder irrigation is not for long-term use.
	www.drugdigest.org /DD/PrintablePages/Monograph/0,7765,8072\|,00.html (486 words)

	Quality Control Guidelines for Testing Gram-Negative Control Strains with Polymyxin B and Colistin (Polymyxin E) by ...
		for colistin, 0.25 to 2 µg/ml (11 to 17 mm), and for polymyxin
		of polymyxin therapies (2, 4, 5, 12, 14) with the subsequent
		Polymyxin B nephrotoxicity and efficacy against nosocomial infections caused by multiresistant gram-negative bacteria.
	jcm.asm.org /cgi/content/full/43/2/925 (1448 words)

	Direct Effects of Polymyxin B on Human Dendritic Cells Maturation: THE ROLE OF I{kappa}B-{alpha}/NF-{kappa}B AND ERK1/2 ...
		Polymyxin B is a lipopolysaccharide binding antibiotic used
		Polymyxin B was purchased from Sigma-Aldrich, dissolved in distilled
		We demonstrate that polymyxin B is not immunologically inert.
	www.jbc.org /cgi/content/full/280/14/14264 (5279 words)

	ICAAC: "Old" Antibiotic Polymyxin B Effective in Treating Drug-Resistant Gram-Negative Infections (Site not responding. Last check: 2007-10-13)
		Kwa said that polymyxin B was used extensively in the 1960s through the 1980s, but its use was abandoned because it was found to give rise to toxicities in the kidneys, nerves and brain.
		Jones, an expert in antibiotic-drug resistance, said he and his associates are dismayed by the lack of antibiotics in development to confront the Gram-negative organisms, especially acinetobacter and pseudomonas species.
		Kwa concluded, "Our preliminary data suggest that polymyxin B is reasonably efficacious and safe in the treatment of multi-drug-resistant infections in the hospital setting." She suggested that the role of polymyxin B in infectious diseases deserves further investigation.
	www.pslgroup.com /dg/23a38e.htm (497 words)

	Neomycin, Polymyxin, and Bacitracin Topical
		Neomycin, polymyxin, and bacitracin combination is used to prevent minor skin injuries such as cuts, scrapes, and burns from becoming infected.
		Neomycin, polymyxin, and bacitracin combination works by stopping the growth of bacteria.
		Neomycin, polymyxin, and bacitracin combination comes as an ointment to apply to the skin.
	www.safemedication.com /displaydrug.cfm?id=601098 (810 words)

	Polymyxin B Nephrotoxicity and Efficacy against Nosocomial Infections Caused by Multiresistant Gram-Negative Bacteria ...
		Polymyxin B Nephrotoxicity and Efficacy against Nosocomial Infections Caused by Multiresistant Gram-Negative Bacteria -- Ouderkirk et al.
		implicate polymyxin as the sole or principal agent causing nephrotoxicity.
		Binding of polymyxin antibiotics to tissue: the major determinant of distribution and persistence in the body.
	aac.asm.org /cgi/content/full/47/8/2659 (2035 words)

	Neomycin, Polymyxin B, and Bacitracin (Topical) - MayoClinic.com (Site not responding. Last check: 2007-10-13)
		Neomycin, Polymyxin B, and Bacitracin (nee-oh-MYE-sin, pol-i-MIX-in bee, and bass-i-TRAY-sin) is a combination antibiotic medicine used to help prevent infections of the skin.
		Neomycin, polymyxin B, and bacitracin combination is available without a prescription; however, your doctor may have special instructions on the proper use of this medicine for your medical problem.
		It is not known whether topical neomycin, polymyxin B, and bacitracin combination passes into breast milk.
	www.mayoclinic.com /health/drug-information/DR202400 (772 words)

	In Vitro Double and Triple Synergistic Activities of Polymyxin B, Imipenem, and Rifampin against Multidrug-Resistant ...
		Synergy was demonstrated with combinations of polymyxin B and
		Time-kill experiments using one-fourth the MIC of each agent (0.25 µg of polymyxin B/ml, 0.5 µg of rifampin/ml, and 8.0 µg of imipenem/ml) alone and in combination for isolates A, B, E, and H. The dotted lines indicate the lower limit of detection of 2 log
		Polymyxin B and rifampin: new regimens for multi-resistant Serratia marcescens infections.
	aac.asm.org /cgi/content/full/48/3/753 (2083 words)

	Combination therapy with polymyxin B for the treatment of multidrug-resistant Gram-negative respiratory tract ...
		Combination therapy with polymyxin B for the treatment of multidrug-resistant Gram-negative respiratory tract infections -- Sobieszczyk et al.
		Combination therapy with polymyxin B for the treatment of multidrug-resistant Gram-negative respiratory tract infections
		Evans, M. E., Feola, D. and Rapp, R. Polymyxin B sulfate and colistin: old antibiotics for emerging multiresistant Gram-negative bacteria.
	jac.oxfordjournals.org /cgi/content/full/54/2/566 (1640 words)

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