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United States Patent Application: 0020031497 A porcine mesencephalic cell, which, in unmodified form, has at least one antigen on the cell surface which is capable of stimulating an immune response against the cell in a xenogeneic subject, wherein the antigen on the cell surface is altered to inhibit rejection of the cell when introduced into the xenogeneic subject. The porcine mesencephalic cell of claim 2, which is contacted prior to transplantation into a xenogeneic subject with at least one anti-MHC class I antibody, or fragment or derivative thereof, which binds to the MHC class I antigen on the cell surface but does not activate complement or induce lysis of the cell. Methods for isolating porcine neural cells from such a pig, in which the pig is tested for the presence or absence of organisms which are capable of transmitting infection or disease to a recipient of the cells, and neural cells isolated, are also within the scope of this invention. appft1.uspto.gov /netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=/netahtml/PTO/srchnum.html&r=1&f=G&l=50&s1='20020009461'.PGNR.&OS=DN/20020009461&RS=DN/20020009461   (17120 words)

Diabetes: Function, mass, and replication of porcine and rat islets transplanted into diabetic nude mice   (Site not responding. Last check: 2007-10-14) Although [beta]-cell mass of porcine and rat grafts was similar at all time periods, recipients of porcine islets required a significantly longer time to reach normal glucose levels; nonetheless, their blood glucose levels continue to decrease and stabilized at levels significantly lower than those of normal mice. Porcine insulin is similar to human insulin, and diabetic patients have been treated with it for decades. Porcine pancreases were obtained from a local slaughterhouse; female Yorkshire pigs 18--24 months of age (weight 350--450 pounds) were used as organ donors. www.findarticles.com /p/articles/mi_m0922/is_n1_v44/ai_16285251   (1085 words)

The Islet Foundation - Expression of PERV by porcine endothelial cells However, excretion of porcine C-peptide by four patients up to 450 days after the transplantation combined with the finding of porcine mitochondrial sequences in serum for 6 months to one year in four patients argue for extended graft survival in at least five patients. Porcine DNA was not detected in the circulation of either patient by any primer pair, even in samples taken only 6 h after dialysis (table). The absence of porcine cells from the circulation of both patients suggests that any porcine cells, probably passenger lymphocytes, that were dislodged from the kidney were rapidly sequestered from the circulation. www.islet.org /41.htm   (9153 words)

Mouse retrovirus mediates porcine endogenous retrovirus transmission into human cells in long-term human-porcine ... Porcine endogenous retrovirus is not transmitted in a discordant porcine-to-cynomolgus xenokidney transplantation model with long-term survival of organ recipients. Porcine endogenous retrovirus transmission characteristics of an inbred herd of miniature swine. Porcine stem cell engraftment and seeding of murine thymus with class II+ cells in mice expressing porcine cytokines: Toward tolerance induction across discordant xenogeneic barriers. www.jci.org /cgi/content/full/114/5/695   (3579 words)

Porcine Somatotropin pST Porcine somatotropin, abbreviated as pST, is a growth hormone naturally produced in pigs. The word "porcine" refers to pigs, and the word "somatotropin" means body growth and refers to the name of the hormone. Porcine somatotropin is active only in pigs and not in humans, cattle, etc. Since it is a protein, pST is digested and made inactive when it is eaten. www.biotech.iastate.edu /biotech_info_series/Porcine_Somatotropin.html   (2254 words)

Swine Diseases Porcine Reproductive and Respiratory Syndrome (PRRS) is rapidly gaining importance as one of the most economically significant diseases to keep out of Texas swine herds. Porcine reproductive and respiratory syndrome (PRRS) is becoming one of the most economically significant diseases of swine. Porcine Reproductive and Respiratory Syndrome (PRRS) was first observed in 1986 in the United States and in 1990 in Europe. www.antwifarms.com /swinediseases.shtml   (3522 words)

Cloning of Porcine CD80 and characterization of human T cell costimulatory activity   (Site not responding. Last check: 2007-10-14) Porcine CD80 was found to be upregulated at 72 hours on lymphocytes upon stimulation with E. To test this, the porcine CD80 gene was then transfected into COS cells to test for cross reactivity and function. When considered with previous findings from this laboratory that porcine endothelial cells can be induced to upregulate the B7's by exposure to human T and NK cells suggests that porcine B7's may play a role in the human anti-porcine cellular response. www.a-s-t.org /library/abstracts99/862.htm   (384 words)

Normal Development in Porcine Thymus Grafts and Specific Tolerance of Human T Cells to Porcine Donor MHC -- Nikolic et ... or porcine fetal thymus with porcine fetal liver (SW/SW SCID). A, Human and porcine lymphocytes in the peripheral blood of SCID mice grafted with HU/HU (n = 5), SW/SW (n = 3), or SW/HU (n = 7) thymus/fetal liver tissue, or with HU THY alone (n = 3), HU FL alone (n = 3), or SW FL alone (n = 3). porcine thymic grafts occurred in the presence of class II cells of porcine origin that had a dendritic morphology. www.jimmunol.org /cgi/content/full/162/6/3402   (3835 words)

Cytokine Profiles in Peripheral Blood Mononuclear Cells and Lymph Node Cells from Piglets Infected In Utero with ... Porcine reproductive and respiratory syndrome virus (PRRSV): kinetics of infection in lymphatic organs and lung. Isolation of porcine reproductive and respiratory syndrome (PRRS) virus in a Danish swine herd and experimental infection of pregnant gilts with the virus. Effect of porcine reproductive and respiratory syndrome virus infection on the clearance of Haemophilus parasuis by porcine alveolar macrophages. cdli.asm.org /cgi/content/full/9/6/1229   (3053 words)

Presh Porcine Cardiac Valves are not Rejected in Primates   (Site not responding. Last check: 2007-10-14) -Gal was not detected on the endothelium of porcine aortic and pulmonary valves. Wild type porcine hearts transplanted into baboon recipients were hyperacutely rejected 60-80 minutes after implantation. Porcine valves are thus protected from xenograft rejection in primates. www.ctsnet.org /doc/4557   (276 words)

Porcine News   (Site not responding. Last check: 2007-10-14) Customers who are using a Smart Coupler to decode aviation format data should return their couplers to Porcine Associates or Navaid Devices for a firmware upgrade. Porcine Associates is proud to release the MPG meter. Now it is possible to have a small, inexpensive meter on your panel that gives you a continuous indication of efficiency over the ground. www.porcine.com /Porcine_News.html   (356 words)

Porcine leptin inhibits lipogenesis in porcine adipocytes -- Ramsay 81 (12): 3008 -- Journal of Animal Science Adipocyte-containing primary cultures were incubated ± porcine leptin (1 to 1,000 ng/mL medium) or 100 nM insulin for 48 h, followed by analysis for LPL activity as described in Materials and Methods. The obesity gene in swine: sequence and expression of porcine leptin. Preparation of recombinant bovine, porcine, and porcine W4R/R5K leptins and comparison of their activity and immunoreactivity with ovine, chicken, and human leptins. jas.fass.org /cgi/content/full/81/12/3008   (5072 words)

Development of a Heteroduplex Mobility Assay To Identify Field Isolates of Porcine Reproductive and Respiratory ... Evolution of porcine reproductive and respiratory syndrome virus during sequential passages in pigs. Porcine reproductive and respiratory syndrome virus: morphological, biochemical and serological characteristics of Quebec isolates associated with acute and chronic outbreaks of porcine reproductive and respiratory syndrome. Molecular cloning and nucleotide sequencing of the 3'-terminal genomic RNA of the porcine reproductive and respiratory syndrome virus. jcm.asm.org /cgi/content/full/41/6/2433   (3907 words)

Porcine Endothelial Cells Porcine large artery endothelial cells are derived from the arteries of USDA–inspected porcine. Porcine artery endothelial cells have been used as a viable alternative for the study of artery endothelial function and metabolism, such as atherosclerosis Each kit contains an ampoule of cryopreserved Porcine Endothelial Cells, 500 ml of Porcine Endothelial Cell Growth Medium (P211-500), and a Subculture Reagent Kit (090K). cellapplications.com /PAOEC.htm   (267 words)

ARS | Publication request: Single Nucleotide Polymorphism (Snp) Discovery in Porcine Expressed Genes   (Site not responding. Last check: 2007-10-14) Markers based on SNPs are suitable for use in high throughput genotyping systems and can be targeted within expressed porcine genes to integrate the porcine/human comparative map. The focus of this research was SNP discovery in expressed porcine genes to develop the porcine/human comparative map. Discovery of 1,650 SNPs in 403 amplicons and strategies for optimizing LSA-based SNP discovery using alternative methods of PCR primer design, data analysis, and germplasm selection that are applicable to other populations and species are described. ars.usda.gov /research/publications/publications.htm?SEQ_NO_115=126956   (345 words)

Heart valves from pigs and the porcine endogenous retrovirus: Experimental and clinical data to assess the probability ...   (Site not responding. Last check: 2007-10-14) Heart valves from pigs and the porcine endogenous retrovirus: Experimental and clinical data to assess the probability of porcine endogenous retrovirus infection in human subjects -- Moza et al. Heart valves from pigs and the porcine endogenous retrovirus: Experimental and clinical data to assess the probability of porcine endogenous retrovirus infection in human subjects Acellularized porcine heart valve scaffolds for heart valve tissue engineering and the risk of cross-species transmission of porcine endogenous retrovirus jtcs.ctsnetjournals.org /cgi/content/abstract/121/4/697   (410 words)

TISSUE SPECIFIC RECOGNITION IN HUMAN ANTI-PORCINE RESPONSE INDICATES PEPTIDE SPECIFICITY IN XENORECOGNITION.   (Site not responding. Last check: 2007-10-14) The human anti-porcine response is of particular interest because of the potential clinical use of porcine organs in human transplantation. A majority of the clones (89%) recognized both the porcine endothelial cells and lymphoblastoid cells from the same pig. Following transfection of a restricted SLA class I gene into both porcine and human cell lines, we found that a majority of the T cell clones (54%) lysed the SLA allele transfected into both pig and human cells. www.a-s-t.org /library/abstracts99/519.htm   (307 words)

Effect of Growth Hormone (GH) on In Vitro Nuclear and Cytoplasmic Oocyte Maturation, Cumulus Expansion, Hyaluronan ... Expression of GH receptor and actin mRNA in porcine oocytes and cumulus cells as detected by reverse transcription-polymerase chain reaction. in vitro by equine chorionic gonadotropin and porcine follicular Gregoraszczuk EL, Bylica A, Gertler A. Response of porcine theca and granulosa cells to GH during short-term in vitro culture. www.biolreprod.org /cgi/content/full/69/3/1013   (7472 words)

Porcine Lung Surfactant Protein D: Complementary DNA Cloning, Chromosomal Localization, and Tissue Distribution -- van ... Porcine Lung Surfactant Protein D: Complementary DNA Cloning, Chromosomal Localization, and Tissue Distribution -- van Eijk et al. Porcine Lung Surfactant Protein D: Complementary DNA Cloning, Chromosomal Localization, and Tissue Distribution Porcine Surfactant Protein D Is N-glycosylated in its Carbohydrate Recognition Domain and Is Assembled into Differently Charged Oligomers www.jimmunol.org /cgi/content/abstract/164/3/1442   (561 words)

Epidermal Growth Factor Enhances Expression of Connexin 43 Protein in Cultured Porcine Preantral Follicles -- Bolamba ... Response of porcine granulosa cells isolated from primary and secondary follicles to FSH, 8-bromo-cAMP and epidermal growth factor in vitro. The regulation of porcine theca cell proliferation in vitro: synergistic actions of epidermal growth factor and platelet-derived growth factor. Effects of epidermal growth factor on the tyrosine phosphorylation of mitogen-activated protein kinases in monolayer cultures of porcine granulosa cells. www.biolreprod.org /cgi/content/full/67/1/154   (4552 words)

Evidence for the Localization of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Antigen and RNA in Ovarian ... Evidence for the Localization of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Antigen and RNA in Ovarian Follicles in Gilts -- Sur et al. Evidence for the Localization of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Antigen and RNA in Ovarian Follicles in Gilts The pathogenesis of porcine reproductive and respiratory syndrome www.vetpathology.org /cgi/content/abstract/38/1/58   (237 words)

Paralogues of Porcine Aromatase Cytochrome P450: A Novel Hydroxylase Activity Is Associated with the Survival of a ... Paralogues of Porcine Aromatase Cytochrome P450: A Novel Hydroxylase Activity Is Associated with the Survival of a Duplicated Gene -- Corbin et al. Paralogues of Porcine Aromatase Cytochrome P450: A Novel Hydroxylase Activity Is Associated with the Survival of a Duplicated Gene This activity was absent in reactions with the porcine placental endo.endojournals.org /cgi/content/abstract/145/5/2157   (254 words)

Mouse retrovirus mediates porcine endogenous retrovirus transmission into human cells in long-term human-porcine ... Mouse retrovirus mediates porcine endogenous retrovirus transmission into human cells in long-term human-porcine chimeric mice -- Yang et al. Mouse retrovirus mediates porcine endogenous retrovirus transmission into human cells in long-term human-porcine chimeric mice Porcine endogenous retrovirus (PERV) is a potential pathogen www.jci.org /cgi/content/abstract/114/5/695   (291 words)

Identification of Neutralizing and Nonneutralizing Epitopes in the Porcine Reproductive and Respiratory Syndrome Virus ... Identification of Neutralizing and Nonneutralizing Epitopes in the Porcine Reproductive and Respiratory Syndrome Virus GP5 Ectodomain -- Ostrowski et al. Identification of Neutralizing and Nonneutralizing Epitopes in the Porcine Reproductive and Respiratory Syndrome Virus GP5 Ectodomain Delputte, P. L., Nauwynck, H. Porcine Arterivirus Infection of Alveolar Macrophages Is Mediated by Sialic Acid on the Virus. jvi.asm.org /cgi/content/abstract/76/9/4241   (445 words)

North American and European porcine reproductive and respiratory syndrome viruses differ in non-structural protein ... North American and European porcine reproductive and respiratory syndrome viruses differ in non-structural protein coding regions -- Allende et al. North American and European porcine reproductive and respiratory syndrome viruses differ in non-structural protein coding regions Porcine B-cells recognize epitopes that are conserved between the structural proteins of American- and European-type porcine reproductive and respiratory syndrome virus vir.sgmjournals.org /cgi/content/abstract/80/2/307   (937 words)

Porcine Reproductive & Respiratory Syndrome (PRRS) - Pig Disease Guide Porcine Reproductive and Respiratory Syndrome (PRRS) : Disease information on pigs, hogs and swine from ThePigSite.com The name porcine arterivirus has been proposed recently. The virus of PRRS has a particular affinity for the macrophages particularly those found in the lung. www.thepigsite.com /DiseaseInfo?Display=97   (1251 words)

Quality of porcine blastocysts produced in vitro in the presence or absence of GH -- Kidson et al. 127 (2): 165 -- ... Quality of porcine blastocysts produced in vitro in the presence or absence of GH -- Kidson et al. Figure 2 Porcine embryo development on Days 2, 5 and 6 of IVC in the absence (Control; n = 1236) or presence (GH; n = 1347) of 100 ng/ml GH (Small Bl = Small blastocysts; Large Bl = Large blastocysts; Total Bl = total blastocysts formed). Table 1 The effect of GH treatment during porcine in vitro embryo culture on different embryo quality parameters in Day 6 in vitro produced blastocysts, as compared with in vivo produced Day 5 blastocysts. www.reproduction-online.org /cgi/content/full/127/2/165   (7171 words)

Development of a Heteroduplex Mobility Assay To Identify Field Isolates of Porcine Reproductive and Respiratory ... Development of a Heteroduplex Mobility Assay To Identify Field Isolates of Porcine Reproductive and Respiratory Syndrome Virus with Nucleotide Sequences Closely Related to Those of Modified Live-Attenuated Vaccines -- Key et al. Development of a Heteroduplex Mobility Assay To Identify Field Isolates of Porcine Reproductive and Respiratory Syndrome Virus with Nucleotide Sequences Closely Related to Those of Modified Live-Attenuated Vaccines Porcine reproductive and respiratory syndrome has been devastating jcm.asm.org /cgi/content/abstract/41/6/2433   (368 words)

In vitro and in vivo characterization of an infectious clone of a European strain of porcine circovirus type 2 -- Roca ...   (Site not responding. Last check: 2007-10-14) In vitro and in vivo characterization of an infectious clone of a European strain of porcine circovirus type 2 -- Roca et al. In vitro and in vivo characterization of an infectious clone of a European strain of porcine circovirus type 2 Detection and in vitro and in vivo characterization of porcine circovirus DNA from a porcine-derived commercial pepsin product vir.sgmjournals.org /cgi/content/abstract/85/5/1259   (371 words)

Synonyms of porcine usage: relating to or suggesting swine; "comparison between human and porcine pleasures" hoggish, piggish, piggy, porcine, swinish, gluttonous (vs. abstemious) usage: resembling swine; coarsely gluttonous or greedy; "piggish table manners"; "the piggy fat-cheeked little boy and his porcine pot-bellied father"; "swinish slavering over food" www.infoplease.com /thesaurus/porcine   (68 words)

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