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Topic: Portal circulation


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In the News (Fri 1 Jan 10)

  
  Portal vein - Wikipedia, the free encyclopedia
A portal vein is a vein that connects two systems of capillary beds.
In contrast to these, a portal vein does not take blood directly to the heart, but instead, takes blood to second capillary bed system.
Hepatic portal vein - often referred to simply as the portal vein, this vein routes blood from the capillary beds of the gastrointestinal tract into the capillary beds of the liver.
en.wikipedia.org /wiki/Portal_vein   (131 words)

  
 Portal venous system - Wikipedia, the free encyclopedia
In human anatomy, the portal venous system (or hepatic portal system) is the system of veins that comprises the hepatic portal vein and its tributaries.
The portal venous system is responsible for directing blood from parts of the gastrointestinal tract to the liver.
Portal hypertension is a condition in which the blood pressure of the portal venous system is too high.
en.wikipedia.org /wiki/Portal_circulation   (389 words)

  
 Vein - Wikipedia, the free encyclopedia
In systemic circulation de-oxygenated blood from the capillary blood vessels is taken by veins to the right part of the heart.
As an exception, in the pulmonary circulation oxygenated blood from the lungs is taken to the left part of the heart by pulmonary veins.
Another special case is portal circulation where the portal vein transports blood rich in products of digestion from the intestines to the liver.
en.wikipedia.org /wiki/Vein   (745 words)

  
 NO overproduction by eNOS precedes hyperdynamic splanchnic circulation in portal hypertensive rats -- Wiest et al. 276 ...
to methoxamine in the in vitro perfused SMAs of portal hypertensive
to be increased in chronic portal hypertension (15, 24, 42).
In vitro hyporeactivity to methoxamine in portal hypertensive rats: reversal by nitric oxide blockade.
ajpgi.physiology.org /cgi/content/full/276/4/G1043   (5205 words)

  
 Portal vein
The portal vein is a major vein in the human body draining blood from the digestive system and its associated glands.
Note that the portal vein drains blood into the liver not from the liver.
Before these absorbed substances can go into the systemic circulation[?] (the main blood circulation in the body), it must be filtered first to remove or "detoxify[?]" toxins first.
www.ebroadcast.com.au /lookup/encyclopedia/po/Portal_vein.html   (162 words)

  
 GE Healthcare - Clinical Case Studies - Sonography - Portal Venous Hypertension
This causes the blood pressure in the hepatic circulation to increase (portal hypertension).
The evaluation of the portal venous system, hepatic veins, and hepatic artery is performed during the Doppler imaging examination.
Portal venous thrombosis or post op anastomosis from a liver transplant can cause an abnormal portal vein signal: results from decreased vessel lumen size which reduces the pressure, and consequently increases the velocity of flow through the narrowed region - "choppy" appearance as result of increased velocities.
www.gehealthcare.com /usen/ultrasound/products/best_prac_pvh.html   (2061 words)

  
 eMedicine - Portal Hypertension : Article by Ali Nawaz Khan, MBBS, FRCP, FRCR   (Site not responding. Last check: 2007-11-01)
Background: Portal hypertension (PH) represents an increase of the hydrostatic pressure within the portal vein or its tributaries and is defined as an increase in the pressure gradient between the portal vein and hepatic veins or inferior vena cava (IVC).
The differential diagnosis of enlarged hepatic artery includes an occluded or interrupted portal vein, a surgical portosystemic shunt, reversal of flow in the portal vein, parenteral feedings in newborns, hereditary hemorrhagic telangiectasia, cirrhosis or hepatic diseases associated with alcohol, vascular hepatic tumors, and primary hepatic artery dissection.
In isolation, increased or decreased echogenicity in the lumen of the portal vein is not sufficient to diagnose or exclude PVT.
www.emedicine.com /RADIO/topic570.htm   (11401 words)

  
 Shunt
The delivery of the portal blood to the liver also ensures that the toxins absorbed from the gastro-intestinal tract are filtered out or inactivated in the liver before the blood is allowed into the rest of the body.
A portosystemic shunt is an abnormal communication between the portal circulation and the systemic circulation (the blood supply to the rest of the body).
In a normal animal the tracer is absorbed into the portal circulation and rapidly transported to the liver.
www.minschnauzer.com /health/shunt.html   (672 words)

  
 Tropical Medicine Central Resource   (Site not responding. Last check: 2007-11-01)
When the intrahepatic portal circulation is diminished, the splenoportogram will fail to show a normal hepatogram.
A The preoperative splenoportogram shows extensive collateral circulation involving the coronary, short gastric, and esophageal plexi (upper arrows) and at the mesenteric vein (arrowhead): there is splenomegaly, but the liver is small.
When there is advanced portal fibrosis, ultrasonography or a T-tube, intravenous or percutaneous cholangiogram may show crowding and narrowing of the intrahepatic biliary radicals.
tmcr.usuhs.mil /tmcr/chapter2/angiography.htm   (764 words)

  
 Li   (Site not responding. Last check: 2007-11-01)
From the lower esophagus and upper stomach the submucosal veins (the intrinsic circulation) perforate the muscularis propria, reach the external surface (extrinsic circulation) and form a periesophageal plexus which drains into the left gastric and splenic veins via short gastro-splenic veins (vasa breviora).
In portal hypertension the portal blood flows back to the splenic vein, spleen, gastro-splenic veins, extrinsic gastro-esophageal veins, intrinsic esophageal veins which become varicose and drain upward through the thoracic and cervical esophagus into the azygos and inferior thyroid veins and into the systemic veins.
Ascites develops in conditions blocking the supra-hepatic (hepatic veins) and intra-hepatic portal circulation (hepatic sinusoids) and very rarely or not at all in those conditions blocking the infra-hepatic circulation (portal vein).
www.meddean.luc.edu /lumen/meded/orfpath/li1.htm   (1263 words)

  
 Ch. 19-20 - Blood vessels and Circulation & Lymphatic System
The systemic circulation, which includes all blood vessels carrying blood from the left ventricle, through body organs, and back to the right atrium; its subdivisions include the coronary (cardiac) circulation, the cerebral circulation and the hepatic portal circulation.
The hepatic portal circulation carries blood from capillaries of the gastrointestinal organs and spleen to sinusoids of the liver; the liver stores, modifies, or detoxifies some of the substances that have been absorbed by the gastrointestinal tract.
The hepatic portal vein is formed by the union of the superior mesenteric vein which drains blood from the small intestine, portions of the large intestine, stomach and pancreas and the splenic vein which drains the spleen and receives tributaries from the stomach, pancreas, and portions of the colon.
main.uab.edu /show.asp?durki=9978   (2362 words)

  
 eMedicine - Esophageal Varices : Article by Cenon Buencamino, MD
Portal hypertension generates hepatofugal flow (reversal of flow), which diverts venous blood uphill in the cephalic direction through the left gastric vein to the venous plexus of the esophagus.
Portal hypertension is diagnosed when the HVPG exceeds 5 mm Hg.
The right portal vein is approximately 0.5-1.5 vertebral body widths to the right of the lateral margin of the spine between the 10th and 12th ribs.
www.emedicine.com /radio/topic269.htm   (8401 words)

  
 UNL Beef Cattle Reports   (Site not responding. Last check: 2007-11-01)
Progesterone concentrations in the hepatic, portal and jugular veins represented 25, 89 and 86 percent of concentrations in the carotid artery, respectively.
Mean concentration of progesterone in the jugular vein during the luteal phase of the estrous cycle of all heifers represented 77 to 92 percent, with an overall average of 86 percent of the concentration in arterial blood.
Mean concentration of progesterone in portal blood was equivalent to 89 percent of the concentrations of progesterone in the carotid artery (range 82 to 93 percent), indicating that progesterone metabolism by portal drained viscera is about 11 percent.
ianrpubs.unl.edu /beef/report/mp71-05.htm   (1317 words)

  
 Systemic Circulation
Systemic circulation supplies nourishment to all of the tissue located throughout your body, with the exception of the heart and lungs because they have their own systems.
Systemic circulation is a major part of the overall circulatory system.
The waste products are collected and the waste-rich blood flows into the veins in order to circulate back to the heart where pulmonary circulation will allow the exchange of gases in the lungs.
sln.fi.edu /biosci/systems/systemic.html   (244 words)

  
 pss BODY
Portal blood is bypassing the liver; therefore the clinical signs noted with portosystemic shunts are related to abnormal liver function.
In animals in which bile acids are not being filtered by the liver (because the liver is abnormal and/or the blood is bypassing the liver) the bile acids become elevated in the blood stream.
Portal hypertension after ameroid constrictor placement is rare and if noted would require additional surgery in an attempt to save the animal.
www.vetmed.auburn.edu /sac/mededu/pss/pss.htm   (4093 words)

  
 Clerkship - USC Department of Surgery   (Site not responding. Last check: 2007-11-01)
Review the portal circulation, and describe the changes that occur in portal hypertension.
Given a patient with portal hypertension, demonstrate the clinical manifestations by physical examination.
Given a patient with portal hypertension, estimate the size of the liver and spleen by physical examination.
www.surgery.usc.edu /clerkship/syllabus-liverportalhypertension.html   (1026 words)

  
 Circulation   (Site not responding. Last check: 2007-11-01)
The pulmonary circulation is also referred to as the lesser circulation.
The main sources are the hepatic artery, which as a branch of the aorta, supplies oxygenated blood to the liver and the hepatic portal vein, which is formed by the union of veins from the spleen, the stomach, pancreas, duodenum and the colon.
The hepatic artery and hepatic portal vein open into the liver sinuses where the blood is in direct contact with the liver cells.
www.botany.uwc.ac.za /SCI_ED/grade10/manphys/circulation.htm   (488 words)

  
 arteries   (Site not responding. Last check: 2007-11-01)
Decreased portal vein pressure and increased hepatic vein pressure are the two requisites for the formation of Zahn infarcts.
The thrombosis of the small intrahepatic portal vein is probably a consequence and not the cause of the infarct.
There is an increased incidence of polyarteritis nodosa in chronic hepatitis B. Intra-parenchymal arteritides, especially in the portal fields, is usually overlooked because of the rarity of their occurrence and because they are confused with non-specific portal inflammations.
www.meddean.luc.edu /lumen/MedEd/orfpath/arteries.htm   (1114 words)

  
 Date RS, et al. Radiofrequency Ablation of the Pancreas. I: Definition of Optimal Thermal Kinetic Parameters and the ...
The portal vein was identified cephalic to the pancreas and the superior mesenteric vein at the inferior border of the gland.
The portal vein was then perfused using normal (non-buffered) saline at 37°C. A pulsed flow rate of 100 mL/min was maintained at a pressure of 100 mmHg.
Thermal injury to the portal vein was characterized by loss of endothelial lining and the presence of oedema in the muscle layer on HandE staining (Figure 4a) and loss of oxidative enzyme activity in the endothelial layer along with patchy preservation of smooth muscle on NADH staining (Figure 4b).
www.joplink.net /prev/200511/05.html   (2527 words)

  
 Library Cards | Circulation | Department Portal | M. Louis Salmon Library
If you have any questions concerning the type of Library privileges that you may be eligible for, please contact the Circulation Desk at 256-824-6530.
In order to receive these privileges you must present, at the Circulation Desk, either an Alumni Card or a photocopy of your diploma, along with a picture I.D. and proof of address.
You will also be required to present a photo ID and proof of address at the Circulation Desk.
www.uah.edu /library/about/department/circulation_library_cards.htm   (722 words)

  
 Cirrhosis
This is called the portal circulation and the large vein through which blood is brought to the liver is called the portal vein.
If the pressure in the portal circulation increases because of cirrhosis and blood back up (note: this can also sometimes occur in severe cases of acute hepatitis and liver damage), blood can flow backwards from the portal circulation to the systemic circulation where they are connected.
Hypertension in the portal circulation, along with other hormonal, metabolic and kidney abnormalities in cirrhosis, can also lead to fluid accumulation the abdomen (ascites) and the peripheral tissue (peripheral edema).
cpmcnet.columbia.edu /dept/gi/cirrhosis.html   (1677 words)

  
 Red Gold . Blood Basics . Blood in the Body . The Circulatory System | PBS
The body's circulatory system really has three distinct parts: circulation through the lungs (pulmonary circulation), the heart (coronary circulation), and the rest of the system (systemic circulation).
Pulmonary circulation, in which blood goes from the heart to the lungs and back to the heart, is when the blood exchanges carbon dioxide, a waste product it has picked up from the rest of the body, for oxygen, which it will carry to the rest of the body.
The de-oxygenated, carbon-dioxide-laden blood returning to the heart from the body enters the right side of the heart through two veins (one for blood coming from the lower half of the body, the other for blood from the upper half).
www.pbs.org /wnet/redgold/basics/circulation.html   (459 words)

  
 Direct Measurement of Pulsatile Insulin Secretion from the Portal Vein in Human Subjects -- Song et al. 85 (12): 4491 ...
observed in the portal circulation was 100-1000 pmol/L in the
A, The portal vein insulin concentration profile and corresponding deconvolved insulin secretion rates obtained during the intensive sampling periods in the basal state (left panels) and during the hyperglycemic clamp periods (right panels) for case 1.
A, The portal vein concentration profile and corresponding deconvolved insulin secretion rates obtained during the intensive sampling periods in the basal state (left panels) and during the hyperglycemic clamp periods (right panels) for case 2.
jcem.endojournals.org /cgi/content/full/85/12/4491   (4945 words)

  
 Mice with targeted deletion of eNOS develop hyperdynamic circulation associated with portal hypertension -- Iwakiri et ...
Role of endothelium in the abnormal response of mesenteric vessels in rats with portal hypertension and liver cirrhosis.
The role of nitric oxide in the vascular hyporesponsiveness to methoxamine in portal hypertensive rats.
Nitric oxide mediates hyporeactivity to vasopressors in mesenteric vessels of portal hypertensive rats.
ajpgi.physiology.org /cgi/content/full/283/5/G1074   (3929 words)

  
 AVMI- Portal Scintigraphy   (Site not responding. Last check: 2007-11-01)
Transcolonic portal scintigraphy involves placement of a radioactive "dye" into the intestine (rectum) of an animal and recording the route of dye absorption.
In a normal animal the dye is absorbed into the portal circulation and rapidly transported to the liver.
Schematic drawing of the normal portal circulation of a rectally administered material.
www.avmi.net /NewFiles/Scintigraphy/Portal.html   (773 words)

  
 Canine Portal Caval Liver Shunt Disease
The portal vein transports blood from the gastro-intestinal system to the liver where it is ''detoxified'' before re-entering the circulatory system "Normally ammonia that has been absorbed through the intestine is carried to the liver by portal circulation, were 81 to 87 percent is converted to urea" (301).
Successful surgeries are more common in shunts located outside the liver than inside, and it is logical to hypothesize that surgical correction of the shunt would result in a spontaneous dissolution of the uroliths (crystals).
In conclusion the portal systemic shunt appears to be growing in frequency however increased clinician skill at detecting the liver-shunt has grown.
clubs.akc.org /astc/health/astchlth/astcshnt   (1707 words)

  
 THE MERCK MANUAL, Sec. 4, Ch. 38, Clinical Features Of Liver Disease
Portal-systemic encephalopathy may occur in fulminant hepatitis caused by viruses, drugs, or toxins, but it more commonly occurs in cirrhosis or other chronic disorders when extensive portal-systemic collaterals have developed as a result of portal hypertension.
In liver disease, these products escape into the systemic circulation if portal blood bypasses parenchymal cells or if the function of these cells is severely impaired.
Treating coma caused by fulminant hepatitis with high-dose corticosteroids or with exchange transfusion and other complex procedures designed to remove circulating toxins has not proved effective.
www.merck.com /mrkshared/mmanual/section4/chapter38/38f.jsp   (907 words)

  
 [No title]
Portal hypertension is an increase in the pressure within the portal vein (the vein that carries blood from the digestive organs to the liver).
The increase in pressure is caused by a blockage in the blood flow throughout the liver.
Increased pressure in the portal vein causes the development across the esophagus and stomach of large veins (varices) to bypass the blockage.
www.qub.ac.uk /cm/sur/webpages/year3/portal-hypertension.doc   (991 words)

  
 Table of contents for Portal hypertension
Anatomy and Vascular Biology of the Cells in the Portal Circulation Massimo Pinzani and Francesco Vizzutti xx 3.
Neovascularization, Angiogenesis and Vascular Remodeling in Portal Hypertension Manuel Morales-Ruiz and Wladimiro Jiménez xxx 8.
Noncirrhotic Portal Hypertension and Portal Vein Thrombosis Shiv Sarin and Manav Wadhavan xxx 26.
www.loc.gov /catdir/toc/ecip0420/2004016771.html   (601 words)

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