
	Where results make sense

Topic: Postexposure prophylaxis

	Prevention and Control \| CDC Rabies
		Routine preexposure prophylaxis for other situations may generally not be indicated.
		Preexposure prophylaxis consists of three doses of rabies vaccine given on days 0, 7, and 21 or 28.
		Postexposure prophylaxis (PEP) is indicated for persons possibly exposed to a rabid animal.
	www.cdc.gov /ncidod/dvrd/rabies/Prevention&Control/preventi.htm (955 words)

	NJDHSS, Division of Communicable Diseases: Guide to Postexposure Rabies Treatment for the Health Care Professional
		Postexposure prophylaxis should be considered when direct contact between a human and a bat has occurred, unless the exposed person can be certain a bite, scratch or mucous membrane exposure did not occur.
		Postexposure prophylaxis should be given even if long delays have occurred since exposure, as therapy may still be effective.
		Postexposure prophylaxis begins with a thorough flushing and cleansing of the wound using water and soap.
	www.state.nj.us /health/cd/pxrabies.htm (2950 words)

	MMWRstdassignment2000
		The recommendation for postexposure prophylaxis (PEP) for percutaneous or permucosal exposure to hepatitis B with a previously vaccinated healthcare worker who is initially known as a nonresponder, when the source person is HBsAg-seropositive, HBsAg-seronegative, or status is unknown.
		The recommendation for postexposure prophylaxis (PEP) for percutaneous or permucosal exposure to hepatitis B with a previously vaccinated healthcare worker who is confirmed to be a nonresponder, when the source person is HBsAg-seropositive, HBsAg-seronegative, or status is unknown.
		The recommendation for postexposure prophylaxis (PEP) for percutaneous or permucosal exposure to hepatitis B with a previously vaccinated healthcare worker whose serologic status is unknown (i.e., an antibody titer was never drawn), when the source person is HBsAg-seropositive, HBsAg-seronegative, or status is unknown.
	www.delta.edu /jahoward/STDs&HBV-HCV-HIV2005-testinginformation.html (1153 words)

	[Clinical Preventive Services] Postexposure Prophylaxis for Selected Infectious Diseases (Site not responding. Last check: 2007-11-03)
		Postexposure prophylaxis should be provided to selected persons with exposure or possible exposure to Haemophilus influenzae type b, hepatitis A, hepatitis B, meningococcal, rabies, or tetanus pathogens (see Clinical Intervention).
		Postexposure prophylaxis is recommended for selected persons with exposure or possible exposure to H. influenzae type b, hepatitis A, hepatitis B, meningococcal, rabies, or tetanus pathogens ("A" recommendation).
		Oral rifampin prophylaxis should be prescribed promptly for patients with Hib disease and for all their household contacts regardless of age, if at least one of the contacts is a child less than 4 years of age who has not been fully vaccinated with a licensed Hib conjugate vaccine.
	cpmcnet.columbia.edu /texts/gcps/gcps0077.html (2581 words)

	NGC - NGC Summary (Site not responding. Last check: 2007-11-03)
		Postexposure prophylaxis in children and adolescents for nonoccupational exposure to human immunodeficiency virus.
		A discussion of risks and benefits of postexposure prophylaxis (PEP) with the family of an exposed toddler will differ from the discussion with a potentially exposed adolescent, whose family may be specifically excluded from knowledge of the whole event.
		Because of the need to begin prophylaxis as quickly as possible after an exposure, office or clinic staff should be instructed to act immediately on telephone calls concerning possible HIV exposure, and the clinician should not wait until the end of the clinic day to return a call.
	www.guideline.gov /summary/summary.aspx?ss=15&doc_id=3841&nbr=3057 (3622 words)

	Postexposure Prophylaxis
		Prophylaxis of infants and young children (less than 2 years old) with day-care exposure to infected cases may also be appropriate.
		Oral rifampin prophylaxis is also indicated for household or day-care contacts of persons with meningococcal infection, as well as for those with direct exposure to oral secretions (e.g., kissing).
		The recommended protocol for postexposure prophylaxis against hepatitis B depends on the nature of the exposure and the HB vaccination status of the exposed person.
	www.telemedical.com /Telemedical/CWS/exposure.html (1667 words)

	FHI - Is HIV Treatment Practical after Exposure?
		Drugs used for postexposure prophylaxis are often not available due to costs, overall drug shortages, or hesitance to recommend a protocol without definitive efficacy data.
		Because prophylaxis should be used as soon as possible after exposure, some experts believe HIV prevention messages should include information about HIV prophylaxis, such as where it can be obtained.
		The recommended postexposure prophylaxis regimen for possible HIV infection is 28 days, which research has found to be difficult to complete.
	www.fhi.org /en/RH/Pubs/Network/v21_1/NW21-1HIVpostexpostretmnt.ht (2461 words)

	RabAvert Rabies Vaccine: RabAvert Package Insert HTML Version (Site not responding. Last check: 2007-11-03)
		Postexposure antirabies treatment should always include administration of both passive antibody (HRIG) and immunization, with the exception of persons who have previously received complete immunization regimens (preexposure or postexposure) with a cell culture vaccine, or persons who have been immunized with other types of vaccines and have had documented rabies antibody titers.
		In the case of postexposure prophylaxis, if an alternative product is not available, the patient should be vaccinated with caution with the necessary medical equipment and emergency supplies available and observed carefully after vaccination.
		When rabies postexposure prophylaxis is administered to persons receiving corticosteroids or other immunosuppressive therapy, or who are immunosuppressed, it is important that a serum sample on day 14 (the day of the fourth vaccination) be tested for rabies antibody to ensure that an acceptable antibody response has been induced (1).
	www.rabavert.com /inserthtml.html (6439 words)

	CDC - Anthrax Postexposure Prophylaxis in Postal Workers, Connecticut, 2001
		Of those starting postexposure prophylaxis, 37 (54%) persons reported missing doses. The top two reasons workers cited for missing a dose were forgetting to take the antibiotic (32%) and side effects (15%).
		The circumstances of this prophylaxis campaign, along with the small sample size and potential for recall bias associated with this survey, limit the inferences that may be drawn.
		Larger postexposure prophylaxis surveys may identify the reason for this and other associations that were not significant in our analysis.
	www.cdc.gov /ncidod/EID/vol8no10/02-0346.htm (2845 words)

	TAMIFLU \| Prophylaxis
		In a pooled analysis of two seasonal prophylaxis studies in healthy unvaccinated adults (aged 13 to 65 years), TAMIFLU 75 mg once daily taken for 42 days during a community outbreak reduced the incidence of laboratory-confirmed clinical influenza from 4.8% (25/519) for the placebo group to 1.2% (6/520) for the TAMIFLU group.
		In a seasonal prophylaxis study in elderly residents of skilled nursing homes, TAMIFLU 75 mg once daily taken for 42 days reduced the incidence of laboratory-confirmed clinical influenza from 4.4% (12/272) for the placebo group to 0.4% (1/276) for the TAMIFLU group.
		Prophylaxis in patients 1 to 12 years of age has not been evaluated for longer than 10 days' duration.Therapy should begin within 2 days of exposure.
	www.tamiflu.com /hcp/prophylaxis/prophy_index.asp (764 words)

	HIV Postexposure Prophylaxis in Adolescents (Site not responding. Last check: 2007-11-03)
		Postexposure prophylaxis is an effective intervention to prevent transmission of the human immunodeficiency virus (HIV).
		The use of postexposure prophylaxis for occupational and perinatal HIV exposures is well established.
		Postexposure prophylaxis: an intervention to prevent human immunodeficiency virus infection in adolescents.
	www.hivandhepatitis.com /recent/pep/050304_b.html (448 words)

	Guidelines for Worker Exposures to HIV and Postexposure Prophylaxis- June 2001 (Site not responding. Last check: 2007-11-03)
		Postexposure prophylaxis (PEP) with hepatitis B immune globulin (HBIG) and/or hepatitis B vaccine series should be considered for occupational exposures after evaluation of the hepatitis B surface antigen status of the source and the vaccination and vaccine-response status of the exposed person.
		Although the postexposure efficacy of the combination of HBIG and the hepatitis B vaccine series has not been evaluated in the occupational setting, the increased efficacy of this regimen observed in the perinatal setting, compared with HBIG alone, is presumed to apply to the occupational setting as well.
		A summary of prophylaxis recommendations for percutaneous or mucosal exposure to blood according to the HBsAg status of the expo-sure source and the vaccination and vaccine-response status of the exposed person is included in this report (Table 3).
	www.hopkins-aids.edu /guidelines/pep/gl_pep.html (14048 words)

	Occupational Exposure to Blood and Body Fluids: New Postexposure Prophylaxis Recommendations (Site not responding. Last check: 2007-11-03)
		Failure of postexposure prophylaxis with ZDV has also been reported.6 This study also attempted to identify risk factors that are significant in occupationally acquired HIV infection.
		The recommendations also state that postexposure prophylaxis should be started promptly, preferably within one to two hours postexposure.
		Postexposure prophylaxis should be initiated only after assessment of risk factors as outlined in Table 1 of the June 1, 1996 Morbidity and Mortality Weekly Report.
	www.cda.org /cda_member/pubs/journal/jour498/exposure.html (2730 words)

	Post-Exposure Prophylaxis
		Havens PL. Postexposure prophylaxis in children and adolescents for nonoccupational exposure to human immunodeficiency virus.
		Postexposure prophylaxis consisted of two 3-week courses of stavudine 40 mg twice a day, lamivudine 150 mg twice a day, and efavirenz 300 mg twice a day.
		Within 6 weeks after the second course of postexposure prophylaxis he developed a rapid increase in abdominal girth, associated with bloating and loss of appetite…The clinical picture resembles the ‘protease paunch’ first described by Miller et al.
	www.aras.ab.ca /haart-PEP.html (1668 words)

	NGC - NGC Summary (Site not responding. Last check: 2007-11-03)
		The decision to administer postexposure chemoprophylaxis is made after considering the infectiousness of the patient and the intensity of the exposure, the potential consequences of severe pertussis in the contact, and possibilities for secondary exposure of persons at high risk from the contact (e.g., infants aged <12 months).
		For postexposure prophylaxis, the benefits of administering an antimicrobial agent to reduce the risk for pertussis and its complications should be weighed against the potential adverse effects of the drug.
		Treatment and postexposure prophylaxis recommendations are made on the basis of existing scientific evidence and theoretical rationale.
	www.guideline.gov /summary/summary.aspx?doc_id=8468&nbr=4726&ss=6&xl=999 (2913 words)

	AEGiS-MMWR: Recommendation of the Immunization Practices Advisory Committee (ACIP) Postexposure Prophylaxis of ...
		Previous recommendations for postexposure prophylaxis have relied on passive immunization with specific hepatitis B immune globulin (HBIG) (1).
		Studies have shown that response to HB vaccine is not impaired by concurrent administration of HBIG and that the combination of HB vaccine and one dose of HBIG produces immediate and sustained high levels of protective antibody to the hepatitis B surface antigen (anti-HBs) (7).
		The primary goal of postexposure prophylaxis for exposed infants is prevention of HBV carrier state.
	www.aegis.com /pubs/mmwr/1984/MM3321-285.html (2423 words)

	HIV Antiretroviral Postexposure Prophylaxis: A Cautionary Note (Site not responding. Last check: 2007-11-03)
		These observations (and their limitations) have led to an explosion of articles about occupational and nonoccupational prophylaxis that focus on the feasibility [69] and the cost (and benefit) [10] of such prevention.
		There are a number of reasons why nonoccupational PEP might have failed, including a lack of adherence to the PEP regimen (at least 3 seroconverters reported a substantial number of missed doses) and a suboptimal drug regimen (all seroconverters received only 2 nucleoside reverse-transcriptase inhibitors).
		Because no resistance was observed in the virus recovered from the newly infected subjects, it implies that the index (source cases) might not have received therapy and that nonoccupational PEP itself did not evoke resistance.
	www.hivdent.org /infctl/ic_HAPP1105.htm (898 words)

	Public Health Service Guidelines for the Management of Health-Care Worker Exposures to HIV and Recommendations for ...
		The decision to recommend HIV postexposure prophylaxis must take into account the nature of the exposure (e.g., needlestick or potentially infectious fluid that comes in contact with a mucous membrane) and the amount of blood or body fluid involved in the exposure.
		In addition, postexposure evaluation for hepatitis B (and possibly hepatitis C) should be provided if contact with saliva includes a possible portal of entry (i.e., nonintact skin, mucous membrane, or percutaneous injury).
		P re- and postexposure chemoprophylaxis: evidence that 3'-azido-3-dideoxythymidine inhibits feline leukemia virus disease by a drug-induced vaccine response.
	www.medadvocates.org /diagnostics/cdc/hcw_guidelines.html (11641 words)

	CIDRAP >> Doxycycline, penicillin G procaine already approved for postexposure prophylaxis against anthrax, FDA notes
		The dosage recommendations are based on the FDA's review of the scientific literature and the same rhesus-monkey study used to support the agency's approval of ciprofloxacin as postexposure prophylaxis for inhalational anthrax, the notice says.
		However, readers should note that this notice does not state that these postexposure prophylaxis recommendations are intended specifically for the current strain of B anthracis that is circulating on the East Coast.
		Therefore, ciprofloxacin and doxycycline are the recommended agents for postexposure prophylaxis during the current outbreak, unless further information becomes available.
	www.cidrap.umn.edu /cidrap/content/bt/anthrax/news/drugnotice.html (606 words)

	Occupational exposure (HIV) include zidovudine postexposure use
		Other physicians believe that zidovudine should not be recommended for uninfected persons after occupational exposures because of the lack of data demonstrating efficacy in postexposure prophylaxis, the limited data on toxicity in uninfected individuals, and the fact that zidovudine has been shown to be carcinogenic in rats and mice.
		The worker should also be informed that there are diverse opinions among physicians regarding the use of zidovudine for postexposure prophylaxis, and the PHS cannot make a recommendation for or against the use of zidovudine for this purpose because of the limitations of current knowledge.
		Studies involving humans should be conducted to determine whether postexposure prophylaxis with zidovudine or other agents is effective, and, if effective, should define the optimal time that postexposure prophylaxis should be initiated and the optimal duration of prophylaxis.
	wonder.cdc.gov /wonder/prevguid/p0000273/p0000273.asp (5019 words)

	ASHP News: CDC Expands HIV Postexposure Prophylaxis Recommendations (Site not responding. Last check: 2007-11-03)
		As with occupational exposures, CDC now recommends prophylaxis, preferably with a three-drug regimen, beginning within 72 hours after exposure outside of the workplace to body fluids from a person known to be infected with HIV.
		Patients seeking postexposure care should be tested for HIV seroconversion at baseline and again at 4–6 weeks, three months, and six months after exposure, according to CDC.
		CDC stated that the limited data on how access to postexposure prophylaxis affects patients' "risk behavior" indicate that patients do not engage in riskier behavior but also may not take action to reduce their exposure risks.
	www.ashp.org /news/ShowArticle.cfm?id=9496 (494 words)

	Persistence of protective immunity after postexposure prophylaxis of varicella with oral aciclovir in the family ...
		Persistence of protective immunity after postexposure prophylaxis of varicella with oral aciclovir in the family setting
		Postexposure prophylaxis of varicella in family contact by oral acyclovir.
		Postexposure prophylaxis of varicella in children with leukemia by oral acyclovir.
	adc.bmjjournals.com /cgi/content/full/78/1/61 (1452 words)

	The Body: Issues in HIV Postexposure Prophylaxis
		The preceding fictional call is very typical of those we receive on the HIV postexposure prophylaxis (PEP) line.
		Postexposure prophylaxis for human immunodeficiency virus (HIV) infection following sexual assault.
		Abbreviated regimens of zidovudine prophylaxis and perinatal transmission of the human immunodeficiency virus.
	www.thebody.com /sfaf/summer00/postexposure.html (2629 words)

	Rabies Postexposure Prophylaxis with Human Diploid
		The studies--one, a passive surveillance system, and the other, a randomized prospective study--demonstrated that not all individuals receiving postexposure prophylaxis with Wyeth Laboratories' HDCV had antibody titers acceptable by the CDC criterion* and that antibody titers after rabies postexposure prophylaxis with Wyeth HDCV were lower than those with Merieux HDCV (IMOVAXTM).
		In the passive surveillance system, sera were examined from 39 persons (in four states) who had completed postexposure prophylaxis with rabies immune globulin (RIG) and five doses of HDCV; 22 had been vaccinated with Merieux vaccine, and 17, with Wyeth vaccine.
		The study participants received rabies postexposure prophylaxis of RIG with five doses of either Merieux or Wyeth vaccine of similar potencies.
	wonder.cdc.gov /wonder/prevguid/p0000258/p0000258.asp (1090 words)

	Postexposure prophylaxis protects newborns from HIV infection (Site not responding. Last check: 2007-11-03)
		Based largely on the results of the HIVNET 012 trial reported in 1999 and 2003, intrapartum prophylaxis with nevirapine has become the standard of care for preventing vertical HIV transmission in developing countries (see Reuters Health story September 11, 2003).
		However, this type of prophylaxis, which involves maternal and infant antiretroviral doses, may not be an option for many pregnant women.
		The new findings, which are reported in the October 11th issue of The Lancet, are based on a study of 1119 infants, born to HIV-infected mothers, who were randomized to receive nevirapine alone or with zidovudine starting immediately after birth.
	www.aidsmeds.com /news/20031009clin005.html (491 words)

	Postexposure Prophylaxis in Children and Adolescents for Nonoccupational Exposure to Human Immunodeficiency Virus -- ...
		Postexposure Prophylaxis in Children and Adolescents for Nonoccupational Exposure to Human Immunodeficiency Virus -- Havens and Committee on Pediatric AIDS 111 (6): 1475 -- Pediatrics
		Efficacy of postexposure prophylaxis after intravaginal exposure of pig-tailed macaques to a human-derived retrovirus (human immunodeficiency virus type 2).
		Pre- and postexposure chemoprophylaxis: evidence that 3'-azido-3'-dideoxythymidine inhibits feline leukemia virus disease by a drug-induced vaccine response.
	pediatrics.aappublications.org /cgi/content/full/111/6/1475 (7787 words)

Try your search on: Qwika (all wikis)