Poxviridae viral particles (virions) are generally enveloped (external enveloped virion- EEV), though the internal mature virion (IMV) form of the virus, which contains no envelope, is also infectious.
The name of the family, Poxviridae, is a legacy of the original grouping of viruses associated with diseases that produced poxs in the skin.
Modern viral classification is based on the shape and molecular features of viruses, and the smallpox virus remains as the most notable member of the family.
Poxviridae viral particles (virions) are generally enveloped (external enveloped virion- EEV), though the internal mature virion (IMV) form of the virus, which contains different envelope, is also infectious.
The prototype of poxvirus family is vaccinia virus, which has been used as a successful vaccine to eradicate smallpox virus.
IEV transports along microtubules to reach cell periphery and fuse with plasma membrane to become cell-associated enveloped virus (CEV) that triggers actin tails on cell surfaces or is releared as EEV.
De Poxviridae zijn onderverdeeld in 2 subfamilies: de Entomopoxvirinae, en de Chordopoxvirinae, op basis van gastheerspecificiteit (insecten vs vertebraten).
De hierboven beschreven virussen behoren tot het genus parapox, en infecties met deze virussen leiden in het algemeen tot gelokaliseerde laesies, zoals beschreven.
Gezien het ontbreken van een betrouwbare surveillance is de vraag hoe hard die bewering is. Wel is duidelijk dat de belangstelling voor Poxviridae vanwege de dreiging van bioterrorisme is toegenomen, wat wellicht heeft geleid tot een grotere alertheid op het optreden van dergelijke infecties.
The resource including Genbank files and fasta files is available for viewing or download for complete Poxviridaegenomes.
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Poxviridae disease : virus diseases caused by the Poxviridae; includes diseases such as smallpox, variola, yaba, molluscum contagiosum, monkeypox, cowpox, lumpy skin disease, infectious myxomatosis, infectious ectromelia, mousepox, etc.
The term Poxviridae disease can be used for:
Other terms that may be related to Poxviridae disease:
Purification and partial characterization of an entomopoxvirus (DlEPV) from a parasitic wasp of tephritid fruit flies.
A-T richness, the possession of the rifampicin resistance gene, and a cytoplasmic site of replication and assembly are characteristics of the Poxviridae (Osborne et al., 1996; Moss, 1996, 2001;Bawden et al., 2000).
Moss B. Poxviridae: the viruses and their replication.
African swine fever (ASF) virus was originally classified as a member of the family Iridoviridae, but the structure of the genome and the replication strategy of the virus have been shown to have many features in common with members of the Poxviridae (Vinuela, 1985).
The proposal that ASF virus be placed in a family separate from the Iridoviridae was accepted at the 6th Meeting of the International Committee on the Taxonomy of Viruses (ICTV) in Sendai (Japan) in 1984.
Using restriction length fragment polymorphism and nucleotide sequencing techniques, numerous strains of ASF virus have been detected, which may vary in virulence.
Naturally, a lot of controversy surrounds the use of live infectious agents as vectors, especially when the vector is a member of Poxviridae and a cousin of Variola, the virus behind smallpox.
As a member of the poxvirus family, the largest and most complex viruses known, vaccinia has relatives that have been around for centuries.
Led by Vaccinia, the Poxviridae may no longer be considered the scourge of the world, but rather powerful tools for advancing research and therapeutic avenues.
HSLS: Poxvirus Bioinformatics Resource Center: a comprehensive Poxviridae informational and analytical resource(Site not responding. Last check: 2007-11-05)
Search and analyze genetic information of the Poxviridae family of viruses.
The Center provides a relational database that supports data storage of poxvirus genomic sequences, and annotation and analysis of poxvirus genes; web-based data mining and sequence analysis tools; software for analysis of complete genomes; a repository of poxvirus species and strains (at ATCC); and a discussion forum.
The 2005 release consists of over 35 complete genomic sequences of various genera, species and strains of viruses from the Poxviridae family.
Background: Poxviridae are a family of oval, quite large, double-stranded DNA viruses.
The genusParapoxvirus is included among these viruses, which measure 260 by 160 nm and possess a unique spiral coat that distinguishes them from the other poxviruses.
So scientists at Canberras Co-operative Research Centre (CRC) for the Biological Control of Pest Animals teamed up with the John Curtin School of Medical Research at the Australian National University in Canberra to create a strain of the mousepox virus that would cause sterility in female mice.
Mousepox is a virus that belongs to a family of viruses known as the Poxviridae.
The pox viruses take their name from the pustules (pocks) that erupt on the skin of infected organisms.
The VBRC is concerned primarily with viruses encompassing the families Arenaviridae, Bunyaviridae, Flaviviridae, Filoviridae, Paramyxoviridae, Poxviridae, and Togaviridae.
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MedicineNet Home > MedTerms medical dictionary A-Z List > Molluscum contagiosum
Molluscum contagiosum: A contagious disease of the skin marked by the occurrence of rounded soft tumors of the skin caused by the growth of a virus (one that belongs to the virus family called the Poxviridae).
The disease is characterized by the appearance of a few to numerous small, pearly, umbilicated downgrowths called molluscum bodies or condyloma subcutaneum.