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Anxiolytics, Sedatives quiz with answers Prazepam is an oral benzodiazepine used for the management of symptoms associated with anxiety disorders and for short-term amelioration of the symptoms of anxiety or anxiety associated with depression. Shorter-duration benzodiazepines are often preferable to prazepam in the treatment of anxiety, particularly in the elderly or patients with liver disease, because prazepam produces an active metabolite with a prolonged half-life. Oxazepam is often preferable to chlordiazepoxide, flurazepam, and prazepam in treating anxiety or insomnia, particularly in the elderly or in patients with liver disease, because oxazepam has a relatively short half-life and does not generate active metabolites. www.rockford.uic.edu /jc/anxiqua.htm   (2638 words)

Prazepam (IARC Summary & Evaluation, Volume 66, 1996)   (Site not responding. Last check: 2007-11-03) Prazepam was tested for carcinogenicity in one experiment in mice and in one experiment in rats by oral administration in the diet. Prazepam is rapidly and extensively absorbed in humans, but its plasma concentrations are low and of short duration as a consequence of its rapid conversion to N-desmethyldiazepam and, to a lesser extent, 3-hydroxyprazepam. Prazepam is extensively metabolized in rats, and the primary metabolite N-desmethyldiazepam is further converted to at least eight derivatives. www.inchem.org /documents/iarc/vol66/prazepam.html   (244 words)

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Prazepam (PIM 680) Prazepam International Programme on Chemical Safety Poisons Information Monograph 680 Pharmaceutical This monograph does not contain all of the sections completed. This mongraph is harmonised with the Group monograph on Benzodiazepines (PIM G008). Prazepam is a white to off-white crystalline powder. www.inchem.org /documents/pims/pharm/pim680.htm   (3162 words)

Prazepam (Centrax®), Serum Prazepam is effective in the treatment of generalized anxiety disorder. Like diazepam, halazepam, and clorazepate, prazepam is converted primarily to desmethyldiazepam, which appears to be the principal active metabolite. This conversion occurs relatively slowly in the liver, and peak levels of desmethyldiazepam are observed approximately six hours after oral administration. www.labcorp.com /datasets/labcorp/html/chapter/mono/td036100.htm   (173 words)

pharmacokinetics and anxiety The reduced levels of desmethyldiazepam may result from a reduction in the conversion of chlorazepate to desmethyldiazepam or to a larger volume of distribution of desmethyldiazepam. Prazepam: Prazepam is dealkylated by the liver to form desmethyldiazepam. Summary: Chlorazepate, diazepam, chlordiazepoxide, and prazepam are metabolized to oxazepam. gerontology.hhs.wmich.edu /~weinreic/tutorial/pharmacokineticsAnxiety.html   (791 words)

Prazepam (Reapam) WAT IS PRAZEPAM EN WAARVOOR WORDT HET GEBRUIKT? Evenals andere benzodiazepinen heeft prazepam naast anxiolytische ook sedatieve (kalmerende), hypnotische (slaap bevorderende), spierverslappende en anticonvulsieve (tegen toevallen) eigenschappen. Prazepam wordt langzaam opgenomen in het lichaam, waarbij piekplasmawaarden na 6 uur worden bereikt. www.hulpgids.nl /medicijnen/medicijnsoorten/prazepam.htm   (1316 words)

PRAZEPAM Drug and Prescription Information, Side Effects, Use, and Dosage PRAZEPAM (Oral) (Tablet) is used for the Treatment Store PRAZEPAM (Oral) (Tablet) at room temperature away from sunlight and moisture unless otherwise stated by manufacturer's instructions or labelling. Keep PRAZEPAM (Oral) (Tablet) and all medications out of the reach of children. www.healthdigest.org /prescription-drug-reference/prazepam-oral-tablet-8953.htm   (414 words)

Drug Information: Prazepam (Print Version) Prazepam is no longer available in the U.S. If you are currently taking prazepam, you should call your doctor to discuss switching to another treatment. Prazepam comes as a tablet and capsule to take by mouth. Prazepam also is used to treat irritable bowel syndrome. www.nlm.nih.gov /medlineplus/print/druginfo/medmaster/a601100.html   (643 words)

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AJC Health : Integrative Medicine  :  Drugs   :  Prazepam | ajc.com If you have an allergy to prazepam or any other part of the medicine. Prazepam works in the brain at the emotional center called the limbic system. Take with food if this medicine causes an upset stomach. www.ajc.com /health/altmed/shared/health/alt_medicine/ConsDrugs/Prazepamcd.html   (520 words)

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DEMETRIN 10 mg (Tablet) Demetrin is contra-indicated in patients with a known hypersensitivity to prazepam or other benzodiazepines; or who have acute narrow-angle glaucoma, or acute pulmonary insufficiency. Some benzodiazepines, such as chlordiazepoxide, have been shown to exacerbate porphyria; therefore caution should be exercised when prazepam is given to porphyric patients. Demetrin is not recommended during pregnancy until such time as its safety in pregnancy has been established. home.intekom.com /pharm/pfizer/demetrin.html   (1050 words)

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Prazepam ( Centrax)   (Site not responding. Last check: 2007-11-03) ive normal volunteers received at a 2-week interval a single dose of sublingual or oral prazepam in double-blind and cross-over conditions. Subjects rated themselves significantly more feeble, clumsy, lethargic, and incompetent following sublingual as compared to oral prazepam while a trend in the same direction was noted for the adjectives muzzy and mentally slow. These results suggest a subjectively more rapid onset of activity following sublingual compared to oral prazepam. www.biopsychiatry.com /prazepam.htm   (112 words)

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