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Topic: Praziquantel


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In the News (Tue 15 Dec 09)

  
  Praziquantel - Wikipedia, the free encyclopedia
Praziquantel and its metabolites are mainly excreted in the urine, within 24 hours after a single oral dose 70 to 80% are recovered in urine, but less than 0.1% are found as the unchanged drug.
Praziquantel (Biltricide) is an antiparasitic (antihelmintic) medication primarily used for the treatment of schistosomiasis (Snail Fever) and fascioliasis (Liver Flukes).
As of 2005 praziquantel is the primary treatment for human schistosomiasis, for which it is usually effective in a single dose.
en.wikipedia.org /wiki/Praziquantel   (545 words)

  
 praziquantel - [Medication]
Praziquantel is used to treat infections caused by worms in the Schistosoma family of worms.
Praziquantel should not be used to treat parasitic infections in the eye.
Praziquantel is in the FDA pregnancy category B. This means that it is not likely to harm an unborn baby.
www.peacehealth.org /kbase/multum/d00349a1.htm   (799 words)

  
 MedlinePlus Drug Information: Praziquantel (Systemic)   (Site not responding. Last check: 2007-10-21)
Praziquantel is used to treat blood fluke infections.
Praziquantel may also be used for other worm infections as determined by your doctor.
Praziquantel has a bitter taste that may cause gagging or vomiting.
www.nlm.nih.gov /medlineplus/druginfo/uspdi/202474.html   (1378 words)

  
 Praziquantel (DroncitĀ®, DrontalĀ®) - PetPlace.com   (Site not responding. Last check: 2007-10-21)
Praziquantel is a parasite-control drug with strong activity against a number of different tapeworms.
The primary use of praziquantel is the control and elimination of tapeworm infections in dogs and cats.
Praziquantel is also available in combination with pyrantel pamoate (which controls roundworms and hookworms), and febantel (which controls roundworms, hookworms and whipworms), and milbemycin [Milbemax®] (which controls roundworms, hookworms, some whipworms [dogs] and prevents heartworms).
www.petplace.com /articles/artShow.asp?artID=1554   (588 words)

  
 Praziquantel
Praziquantel is primarily used against parasites known as "Cestodes" (tapeworms).
Praziquantel acts by inciting damage to the parasite's skin internally such that the parasite disintegrates and is removed by the host's immune system.
Praziquantel is felt to be safe for use in pregnant patients.
www.marvistavet.com /html/body_praziquantel.html   (238 words)

  
 Evidence Against Rapid Emergence of Praziquantel Resistance in Schistosoma haematobium, Kenya
The potential for development of praziquantel resistance in the study population was first estimated by the Hardy-Weinberg equilibrium analysis (28).
The yearly efficacy of praziquantel treatment and infection or reinfection rates (egg-negative to egg-positive conversion) were compiled for the study population (Table 1).
Schistosomiasis japonica in the Philippines: the long-term impact of population-based chemotherapy on infection, transmission, and morbidity.
www.cdc.gov /ncidod/eid/vol6no6/king.htm   (4715 words)

  
 NADA 138-455
Praziquantel did not interfere with the activity of pyrantel for removal of either parasite.
Neither the presence of praziquantel nor febantel interfered with the nematocidal activity of pyrantel.
Praziquantel + pyrantel tablets were not efficacious for the removal of whipworms.
www.fda.gov /cvm/FOI/1317.htm   (5501 words)

  
 KoiVet.com - Praziquantel For Flukes - So Long, Fluke Tabs!   (Site not responding. Last check: 2007-10-21)
What it is: Praziquantel is a bitter tasting powder which shows good absorption directly from the treated water, and then admirable clearance of various surface and internal flukes (trematodes) and internal worms in fish.
Praziquantel does not require water changes, praziquantel is harmless to fish of *all* species including Discus, Koi and goldfish fry, and is non toxic to plants, and; (unlike Formalin), praziquantel has no negative filter impact.
Praziquantel was traditionally available in the form of branded Droncit tablets, for oral administration in dogs and cats.
www.koivet.com /html/articles/articles_print.php?article_id=198   (969 words)

  
 Praziquantel   (Site not responding. Last check: 2007-10-21)
Praziquantel may be prescribed to treat other types of parasite-related disease as determined by your physician.
Praziquantel should not be used when Taenia solium worm cysts are present in the eye.
The death of the worm cysts by praziquantel may cause irreparable damage to the eyes.
www.wholehealthmd.com /refshelf/drugs_view/1,1524,512,00.html   (580 words)

  
 Emerging Infectious Diseases: Evidence against rapid emergence of praziquantel resistance in schistosoma haematobium, ...
Until there are polymerase chain reaction probes for praziquantel resistance, the prevalence of genes for resistance to praziquantel could be estimated by giving two--or preferably three--treatments of praziquantel at monthly intervals and determining the reduction in egg counts after each round of treatment.
Diminished susceptibility to praziquantel in a Senegal isolate of Schistosoma mansoni.
In vitro responses of praziquantel-resistant and -susceptible Schistosoma mansoni to praziquantel.
www.findarticles.com /p/articles/mi_m0GVK/is_6_7/ai_80951255   (614 words)

  
 Combination Chemotherapy of Schistosomiasis in Laboratory Studies and Clinical Trials -- Utzinger et al. 47 (5): 1487 ...
Chemotherapy with praziquantel is the mainstay for morbidity
Increased exposure of parasite antigens at the surface of adult male Schistosoma mansoni exposed to praziquantel in vitro.
Activity of praziquantel, an isoquinoline-pyrazino derivative, on mice, hamsters and Cebus monkeys.
aac.asm.org /cgi/content/full/47/5/1487   (5389 words)

  
 Interaction between Grapefruit Juice and Praziquantel in Humans -- Castro et al. 46 (5): 1614 -- Antimicrobial Agents ...
inhibition of praziquantel hydroxylation by compounds that are
of praziquantel (6, 12); therefore, the aim of this study was
Pharmacokinetic study of praziquantel administered alone and in combination with cimetidine in a single-day therapeutic regimen.
aac.asm.org /cgi/content/full/46/5/1614   (1506 words)

  
 Caution With Praziquantel in Neurocysticercosis -- Fong et al. 28 (8): 1648 -- Stroke
with praziquantel because its plasma levels are lowered by steroids.
praziquantel therapy or were a sign of neurocysticercosis itself.
the use of praziquantel in patients with neurocysticercosis.
stroke.ahajournals.org /cgi/content/full/28/8/1648/a   (850 words)

  
 Clinical Study: 85-I-0127, Treatment of Patients with Cysticercosis with Praziquantel or Albendazole   (Site not responding. Last check: 2007-10-21)
The purpose of this study is to evaluate, treat and follow patients with cysticercosis, an infection with the larval form of the pork tapeworm, T. solium.
The drugs praziquantel and albendazole are used to treat cysticercosis, but it is not clear if these drugs are effective in all patients, such as those with calcified cysts or brain enlargement.
Cimetidine-induced rise in praziquantel levels in a patient with neurocysticercosis being treated with anticonvulsants
clinicalstudies.info.nih.gov /cgi/detail.cgi?A_85-I-0127.html   (555 words)

  
 Praziquantel (Systemic) - MayoClinic.com   (Site not responding. Last check: 2007-10-21)
Praziquantel (pray-zi-KWON-tel) belongs to the family of medicines called anthelmintics(ant-hel-MIN-tiks).
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur.
The presence of other medical problems may affect the use of praziquantel.
www.mayoclinic.com /health/drug-information/DR202474   (1386 words)

  
 FishDoc.net - Using Praziquantel for Fluke infestations   (Site not responding. Last check: 2007-10-21)
Long tapeworms are sometimes found on the bottom of the treatment tank.
Praziquantel was traditionally available in the form of branded
Praziquantel is expected to be commercially available early in
www.fishdoc.net /articles/details.php?articleId=25   (618 words)

  
 Clinical Trial Of Praziquantel And Prednisone In Rural Patients With Neurocysticercosis Presenting With Recurrent ...
In places like former Transkei where combination of NCC, CNS Schistosomiasis, PTB and retroviral infections can be present, regular cycles of praziquantel and prednisone (also kills Schistosoma mansoni) should be done until this picture will be changed by a good primary health care system.
The severity of the infection in patients with more than fifty viable cysticercus, associated calcified lesions with perilesional edema, and increased number of re-infections suggest additional course of praziquantel or regular cycles; our proposal is one day treatment every month for six month, regular assessment and reconsider further courses.
One day of treatment with praziquantel at doses of 100mg/kg/day divided in dosage of 25 mg/kg 3 hourly and 40 mg of prednisone for 4 days can be the treatment of choice for patients with recurrent seizures and mixed forms of NCC.
www.ispub.com /ostia/index.php?+xmlFilePath=journals/ijn/vol1n2/ncc.xml   (1595 words)

  
 Praziquantel Report   (Site not responding. Last check: 2007-10-21)
This report identifies national and international policies that have facilitated or hindered the availability of praziquantel, the drug of choice for all forms of schistosomiasis occurring in humans.
The analysis of praziquantel illustrates more general problems in the design of national and international policies for tropical disease products, and suggests strategies for future research and action.
This research project was carried out through the Takemi Program in International Health, at the Harvard School of Public Health (665 Huntington Avenue, Boston, MA, USA 02115), with the financial support of the Edna McConnell Clark Foundation.
www.hsph.harvard.edu /takemi/pzq/pzq.html   (163 words)

  
 Praziquantel (Droncit) - VeterinaryPartner.com - a VIN company!
The common tapeworm of dogs and cats, Dipylidium caninum, is the usual target though praziquantel is also effective against less common types of tapeworms such as Taenia species and the more dangerous Mesocestoides species.
A single treatment of praziquantel should clear a Dipylidium caninum infection though a second treatment is sometimes recommended if it is felt that immediate reinfection is likely.
It has been reported that approximately one cat in 10 will experience weakness, salivation, or nausea after a tapeworm injection with praziquantel, but we have seen such reactions far less frequently.
www.veterinarypartner.com /Content.plx?P=A&A=531&S=1&SourceID=52   (302 words)

  
 Healthopedia.com Drugs Information - Praziquantel : Proper Use (Biltricide)
You are here : Healthopedia.com > Drugs and Medications > Detailed Drug Information (USP DI) > Praziquantel : Proper Use
Dosing—The dose of praziquantel will be different for different patients.
Links to other sites are provided for information only -- they do not constitute endorsements of those other sites.
www.healthopedia.com /drugs/detailed/praziquantel/proper-use.html   (543 words)

  
 Dog Worm, Worm In Dog, Piperazine, Praziquantel, Nemex   (Site not responding. Last check: 2007-10-21)
Praziquantel Canine Tape Worm Tabs, 5 x 34 mg Tabs
This is the only FDA approved Praziquantel for over the counter sales.
Praziquantel Feline Tape Worm Tabs, 3 x 23 mg Tabs
lambriarvet.com /Wormers-Small-Animal.php   (791 words)

  
 Trade Winds Praziquantel Feline Tape Worm Tabs - PetFoodDirect
Field trials have shown Praziquantel Tape Worm Tabs to be 100% effective and safe for the removal of common tapeworms in adult cats and kittens.
Cats can be infested with two types of tapeworms.
However, Praziquantel Feline Tape Worm Tabs are now available without a prescription, and are 100% effective in ridding your pet of both types of tapeworms.
petfooddirect.com /store/product_detail.asp?pf_id=30936901&...&Page=   (225 words)

  
 Single-day praziquantel versus 1-week albendazole for neurocysticercosis -- Del Brutto et al. 52 (5): 1079 -- Neurology
Single-day praziquantel versus 1-week albendazole for neurocysticercosis -- Del Brutto et al.
with praziquantel (100 mg/kg in three divided doses at 2-hour
from 59 to 24 in those treated with praziquantel, the number
www.neurology.org /cgi/content/abstract/52/5/1079   (322 words)

  
 Mycotricide (Praziquantel)
You can save more 80% on Mycotricide - Praziquantel.
Generic name: Praziquantel, Manufacturer: Bayer, Size: 10 tabs
Generic name: Praziquantel, Manufacturer: ATC Corp, Size: 8 tabs, Expire: Apr/2008
www.1meds.com /Mycotricide.html   (60 words)

  
 Praziquantel/Albendazole? Nagging Q Forums PLAB AIPPG USMLE   (Site not responding. Last check: 2007-10-21)
(I think Praziquantel is the drug of first choice in Neurocysticercosis.Anyone disagrees?)
Some studies suggest that it has higher response rate than praziquantel, but these studies were not controlled for pharmacologic interactions between praziquantel and other drugs.
When used optimally (using praziquantel with cimetidine), drugs are probably equivalent
www.aipge.com /postt34034.html   (251 words)

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