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| | Prednisolone Ineffective Against HIV-Associated Pleural Tuberculosis (Site not responding. Last check: 2007-10-08) |
 | | The investigators noted that, although prednisolone suppresses the immune system's response to tuberculosis when used alone, its use is associated with improved survival when taken with anti-tuberculosis drugs--notably, in pericardial tuberculosis. |
 | | As prednisolone is relatively inexpensive and widely available, this would have been of value in fighting tuberculosis and HIV co-infection, especially in resource-poor regions of the world as sub-Saharan Africa. |
 | | Although prednisolone use was not associated with such HIV-associated opportunistic diseases as cryptococcal meningitis, esophageal or oral candidiasis, herpes zoster, or oral or genital herpes simplex infection, it did significantly increase the risk of Kaposi's sarcoma, six cases of which were observed, and only in the prednisolone group. |
| www.pslgroup.com /dg/244ae6.htm (510 words) |
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