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Topic: Primary hyperparathyroidism


  
  Primary hyperparathyroidism - Wikipedia, the free encyclopedia
Primary hyperparathyroidism causes hypercalcemia (elevated blood calcium levels) through the excessive secretion of parathyroid hormone (PTH), usually by an adenoma (benign tumors) of the parathyroid glands.
The classic bone disease in hyperparathyroidism is osteitis fibrosa cystica, which results in pain and sometimes pathological fractures.
Primary hyperparathyroidism is also a feature of several familial endocrine disorders: Multiple endocrine neoplasia type 1 and type 2A (MEN type 1 and MEN type 2A), and familial hyperparathyroidism.
en.wikipedia.org /wiki/Primary_hyperparathyroidism   (349 words)

  
 Hyperparathyroidism - Wikipedia, the free encyclopedia
Primary hyperparathyroidism results from a dysfunction in the parathyroid glands themselves, with oversecretion of PTH.
Secondary hyperparathyroidism is due to resistance to the actions of PTH, usually due to chronic renal failure.
Once an elevated PTH has been confirmed, goal of diagnosis is to determine whether the hyperparathyroidism is primary or secondary in origin by obtaining a serum calcium level.
en.wikipedia.org /wiki/Hyperparathyroidism   (327 words)

  
 Lifespan's A - Z Health Information Library - Hyperparathyroidism
This is called "primary hyperparathyroidism" and is caused by enlargement of one or more of the parathyroid glands.
In primary hyperparathyroidism, mild hypercalcemia may be followed medically unless impaired renal function, bone demineralization, mental status changes or high blood pressure is present.
Secondary hyperparathyroidism is treated by restoring the calcium back into the normal range, usually by giving calcium and vitamin D alone or in combination, depending on the underlying disorder.
www.lifespan.org /adam/healthillustratedencyclopedia/1/001215.html   (573 words)

  
 Home | aHealthyme.com
Primary hyperparathyroidism occurs as a malfunction of one of the glands, usually as a result of a benign tumor, called adenoma.
Primary hyperparathyroidism is one of the most common endocrine disorders, led only by diabetes and hyperthyroidism.
Hyperparathyroidism cases will usually be referred to an endocrinologist, a physician specializing in hormonal problems, or a nephrologist, who specializes in kidney and mineral disorders.
www.ahealthyme.com /article/gale/100084734   (1076 words)

  
 Parathyroid Hyperthyroidism - Print Version : Online Reference For Health Concerns
Hyperparathyroidism inflicts damage to the body because it causes an abnormally high level of calcium in the blood, which slowly destroys the tissues by accelerating the calcification process.
Although primary hyperparathyroidism normally mandates surgery to remove one or more parathyroid glands that have developed benign tumors, secondary hyperparathyroidism can be caused by a dietary calcium or vitamin D deficiency.
Elderly postmenopausal women with primary hyperparathyroidism who are not candidates for surgery may consider estrogen-replacement therapy combined with either calcitriol or calcium supplements for the treatment of osteoporosis.
www.lef.org /protocols/prtcls-txt/t-prtcl-087.html   (3399 words)

  
 OBGYN.net - Primary Hyperparathyroidism in Pregnancy - a review
Though Primary hyperparathyroidism is considered rare in pregnancy, and only about 110 cases have so far been reported in world literature this is probably a considerable underestimate of its prevalence in pregnant patients.
A diagnosis of primary hyperparathyroidism was then made and the patient underwent an ultrasound scan of the neck.This revealed a 0.5 cm hypoechogenic lesion dorsal to the left lobe of the thyroid.
Primary hyperparathyroidism usually arises out of a single parathyroid adenoma in 90% of cases, multiglandular hyperplasias in about 8-10% of cases and carcinomas in about 1-2% of cases.
www.obgyn.net /pb/pb.asp?page=/pb/articles/Primary_Hyperparathyroidism   (1393 words)

  
 Article : Extensive Skeletal Manifestations in a Case of Primary Hyperparathyroidism Caused by Parathyroid Adenoma ; ...   (Site not responding. Last check: 2007-08-23)
Classical findings of advanced hyperparathyroid skeletal disease are rarely being encountered today, probably reflecting the earlier detection rate, the greater preponderance of benign chemical hyperparathyroidism and possible preventive effect on bone resorption due to a changing diet with abundant calcium, phosphate and vitamin D. Less than half of the patients with hyperparathyroidism manifest skeletal lesions.
Primary hyperparathyroidism is due to a solitary adenoma in 80% of the patients and to glandular hyperplasia in 20%.
Primary hyperparathyroidism primarily involves patients between the age of 40 and 80, with a female predominance of 3 : 1.
www.ijri.org /articles/archives/2002-12-2/musculoskeletal_267.htm   (1140 words)

  
 Primary Hyperparathyroidism
S. Mark Overholt, M.D. Primary hyperparathyroidism (HPT) is the number one cause of hypercalcemia in the non-hospitalized patient, with malignancy predominating in hospitalized patients.
Primary hyperparathyroidism is the result of an adenoma, glandular hyperplasia, or carcinoma.
Cope, in his classic monograph reporting the first 343 cases of primary hyperparathyroidism from the Massachusetts's General Hospital, described the classic symptoms of nephrolithiasis, bone diseases, abdominal groans from peptic ulcer disease and pancreatitis, psychic moans from fatigue and CNS disturbance, and hypertension that characterize this disease.
www.bcm.edu /oto/grand/12094.html   (2849 words)

  
 eMedicine - Hyperparathyroidism : Article by Lawrence Kim
Primary hyperparathyroidism is the unregulated overproduction of PTH resulting in abnormal calcium homeostasis.
In patients with secondary hyperparathyroidism due to vitamin D deficiency, the symptoms are mainly due to the vitamin deficiency (eg, osteomalacia with increased fracture risk, myopathy [rarely]).
Tertiary hyperparathyroidism is secondary to long-standing secondary hyperparathyroidism.
www.emedicine.com /MED/topic3200.htm   (5639 words)

  
 eMedicine - Hyperparathyroidism, Primary : Article by Bonnie Freitas, MD
Primary hyperparathyroidism is the most common cause of hypercalcemia in the outpatient population, second only to malignancy in the inpatient population.
Hyperparathyroidism in pregnancy is associated with increased perinatal morbidity and mortality rates related to hypocalcemic tetany in the newborn.
Pugh DG: Subperiosteal resorption of bone, a roentgenologic manifestation of primary hyperparathyroidism and renal osteodystrophy.
www.emedicine.com /radio/topic355.htm   (4042 words)

  
 Hyperparathyroidism in Cats
Hyperparathyroidism is a condition in which the parathyroid glands (not the thyroid glands!) produce too much parathyroid hormone.
Primary hyperparathyroidism is generally seen in older animals and is more common in dogs than cats.
Secondary hyperparathyroidism is more common and occurs most frequently in kittens and puppies fed an all-meat or organ diet (such as all liver) or a diet with an imbalance of calcium and phosphorous.
www.peteducation.com /article.cfm?cls=1&cat=1340&articleid=298   (420 words)

  
 UpToDate Patient information: Primary hyperparathyroidism
Hyperparathyroidism can also occur if one or more of the parathyroid glands becomes enlarged due to an overgrowth of normal cells, which is a condition called hyperplasia.
Hyperparathyroidism may occur at young ages, but in such instances it is more likely to be a manifestation of a familial syndrome of hyperparathyroidism, where parathyroid gland hyperplasia is more likely than adenoma.
Conversely, hyperparathyroidism in developing countries where calcium testing is not routine, the disease may be more symptomatic with a higher prevalence of kidney stones and bone disease including bone pain and fractures.
patients.uptodate.com /topic.asp?file=endo_hor/2367   (1542 words)

  
 Primary Hyperparathyroidism
Primary hyperparathyroidism is a disorder of the parathyroid glands.
In secondary hyperparathyroidism, a problem such as kidney failure makes the body resistant to the action of parathyroid hormone.
Very rarely, hyperparathyroidism is caused by cancer of a parathyroid gland.
www.habibintl.com /primary_hyperparathyroidism.htm   (294 words)

  
 Hyperparathyroidism   (Site not responding. Last check: 2007-08-23)
Primary hyperparathyroidism is a disorder of the parathyroid glands, also called parathyroids.
In 85 percent of people with primary hyperparathyroidism, a benign tumor called an adenoma has formed on one of the parathyroid glands, causing it to become overactive.
Hyperparathyroidism is diagnosed when tests show that blood levels of calcium and parathyroid hormone are too high.
endocrine.niddk.nih.gov /pubs/hyper/hyper.htm   (1468 words)

  
 Primary Hyperparathyroidism   (Site not responding. Last check: 2007-08-23)
Primary hyperparathyroidism is a metabolic disorder in which one (or more) of the parathyroid glands produces too much parathyroid hormone, which can result in the loss of bone tissue.
Primary hyperparathyroidism affects about 100,000 people in the US each year, and is more prevalent in women
A diagnosis procedure for primary hyperparathyroidism may involve a dual x-ray absorptiometry, also called bone densitometry, to determine bone density and to reveal loss of bone tissue.
www.healthsystem.virginia.edu /uvahealth/adult_bone/hyperpar.cfm   (344 words)

  
 Hyperparathyroidism
Primary hyperparathyroidism is characterized by an overproduction of parathyroid hormone, which, in turn, results in an elevation of calcium levels in the blood.
The diagnosis of primary hyperparathyroidism is made mostly on the basis of lab tests that show high levels of calcium and parathyroid hormone.
Once a provider suspects that a person has primary hyperparathyroidism, he or she will do a physical examination and will ask about symptoms of abdominal pain and constipation, depression, anxiety, memory loss, muscle weakness, and urinary problems.
www.umm.edu /altmed/ConsConditions/HyperparathyroidismPrimarycc.html   (1296 words)

  
 New York Thyroid Center: Hyperparathyroidism
Most cases (85%) of hyperparathyroidism are the result of a single parathyroid gland malfunctioning and developing into a benign tumor, known as an adenoma.
Oftentimes a person with hyperparathyroidism has no symptoms, or they attribute their symptoms to other causes, and they first learn about the disease from blood tests taken during a routine visit to the doctor.
Hyperparathyroidism is diagnosed by simple blood tests which check the blood level of calcium as well as a blood level of parathyroid hormone.
cpmcnet.columbia.edu /dept/thyroid/hyperpara.html   (707 words)

  
 PRIMARY HYPERPARATHYROIDISM: KING KHALID
Primary hyperparathyroidism is a relatively common disorder in Western countries, with an annual incidence of 28 per 100,000 population in the USA.
Twenty-one (87.5%) of the 24 primary hypertension-parathyroid patients underwent bilateral neck exploration with the excision of abnormal parathyroid (PT) gland(s) and visualization of the remaining normal glands.
Primary hyperparathyroidism, with its diverse presentations and potential complications, is still a challenging disease for physicians and surgeons alike.
www.kfshrc.edu.sa /annals/192/98-180.html   (3189 words)

  
 Parathyroid Gland
Primary hyperparathyrodism means that your parathyroid hormone and calcium levels are elevated.
This occurs in 92-94 percent of patients with primary hyperparathyroidism.
Cancer — This is very uncommon and is the cause of primary hyperparathyroidism in fewer than 0.5 percent of cases.
www.med.nyu.edu /fgpsurgicaloncology/programs/thyroid_parathyroid/parathyroid.html   (1377 words)

  
 Hyperparathyroidism - WrongDiagnosis.com
Hyperparathyroidism refers to an excess secretion of hormones by the parathyroid glands, and this alters calcium metabolism.
Primary hyperparathyroidism is associated with neoplasia or hyperplasia.
The prognosis of Hyperparathyroidism may include the duration of Hyperparathyroidism, chances of complications of Hyperparathyroidism, probable outcomes, prospects for recovery, recovery period for Hyperparathyroidism, survival rates, death rates, and other outcome possibilities in the overall prognosis of Hyperparathyroidism.
www.wrongdiagnosis.com /h/hyperparathyroidism/intro.htm   (744 words)

  
 Hyperparathyroidism   (Site not responding. Last check: 2007-08-23)
Hyperparathyroidism is a disorder in which too much parathyroid hormone (PTH) is secreted from the parathyroid glands, resulting in abnormally high levels of calcium in the blood (hypercalcemia).
Primary hyperparathyroidism is more common than either secondary or tertiary hyperparathyroidism, which occurs in patients with kidney failure or a severe vitamin D deficient state.
In primary hyperparathyroidism, parathyroidectomy results in a 95% cure rate with normalization of serum calcium, and increase in bone density with reduced risk of kidney stones.
healthlibrary.epnet.com /GetContent.aspx?token=9cc295f8-f3b0-4b15-99b3-beb1e6cbe599&chunkiid=96737   (865 words)

  
 ENLmedical.com: Conditions And Concerns: Medical Encyclopedia: Primary hyperparathyroidism
In primary hyperparathyroidism, increased secretion of parathyroid hormone occurs because of enlargement of 1 or more of the glands, or because of parathyroid adenoma.
In children, hyperparathyroidism tends to be caused by hyperplasia (increased number of cells) of all of the parathyroid glands.
Hyperparathyroidism in childhood is usually familial (it occurs in families).
www.enlmedical.com /article/000384.htm   (447 words)

  
 Hyperparathyroidism   (Site not responding. Last check: 2007-08-23)
Familial endocrine neoplasia type I is one rare inherited syndrome that affects the parathyroids as well as the pancreas and the pituitary gland.
Patients with hyperparathyroidism may be more likely to develop peptic ulcers, high blood pressure, and pancreatitis.
Other diseases can cause high blood calcium levels, but only in hyperparathyroidism is the elevated calcium the result of too much parathyroid hormone.
www.clevelandclinic.org /health/health-info/docs/1000/1012.asp?index=5848&sr   (1306 words)

  
 Hyperparathyroidism
Hyperparathyroidism can occur as one of two types — primary hyperparathyroidism or secondary hyperparathyroidism.
In rare cases, hyperparathyroidism may be caused by cancer of one of the parathyroid glands.
Because hyperparathyroidism often causes few if any symptoms, you may not know you have the disorder until your doctor notices high levels of calcium on routine blood tests or on tests that screen for other disorders.
www.cnn.com /HEALTH/library/DS/00396.html   (2049 words)

  
 MDchoice.com The Ultimate Medical Information Finder Primary Hyperparathyroidism Disorder
A person with hyperparathyroidism may have severe symptoms, subtle ones, or none at all.
Hyperparathyroidism is diagnosed when tests show that blood levels of calcium as well as parathyroid hormone are too high.
Surgery for hyperparathyroidism is highly successful with a low complication rate when performed by surgeons experienced with this condition.
www.mdchoice.com /Pt/consumer/Hyperparathyroidism.asp   (1222 words)

  
 UCLA Department of Medicine - wfsection-Primary Hyperparathyroidim in Pregnancy
Thus, it is important for these physicians to be familiar with the diagnosis, complications and treatment of hyperparathyroidism in pregnancy.The following case report details the diagnosis, treatment, and outcome of a woman cared for in our family practice office, whose pregnancy was complicated by primary hyperparathyroidism.
Fetal distress (most likely not related to the hyperparathyroidism) was noted at 8cm dilatation, and the patient underwent a cesarean section to deliver an 8-pound girl with APGARS 8 and 9.
In general, pancreatitis, complicating hyperparathyroidism of pregnancy, is much more prevalent than it is in hyperparathyroidism among the non-pregnant population.
www.med.ucla.edu /modules/wfsection/article.php?articleid=138   (1662 words)

  
 Tc-99m Sestamibi Scintigraphy in Primary Hyperparathyroidism
Primary hyperparathyroidism is a relatively common disease, occurring in about one of every 500 women over 40 years of age and in about one of every 2000 men.
Most cases (80-85%) of primary hyperparathyroidism are the result of single adenomas.
The primary virtues of scintigraphy are that its sensitivity and specificity are not affected by the previous surgery and its ability to localize ectopic adenomas.
www.med.harvard.edu /JPNM/TF96_97/Oct1/WriteUp.html   (1152 words)

  
 Hyperparathyroidism
In hyperparathyroidism the parathyroid hormone (PTH) level is elevated, the number of osteoblasts is markedly increased, and the bones become porous.
In hyperparathyroidism BMD values can differ very much per bone, (2) and some BMD values can even be elevated (3) due to increased osteoblast activity.
Even if in hyperparathyroidism the calcitriol level is normal, the continued uptake of dietary calcium would add up to the accelerated fractional calcium absorption and subsequent deportation, further hastening osteoporosis.
www.4.waisays.com /hyperpara.htm   (799 words)

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