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Topic: Primary sclerosing cholangitis

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	CIGNA - Primary Sclerosing Cholangitis (Site not responding. Last check: 2007-10-23)
		Primary sclerosing cholangitis is a rare progressive disorder characterized by inflammation, thickening, and abnormal formation of fibrous tissue (fibrosis) within the passages that carry bile from the liver (bile ducts).
		Primary sclerosing cholangitis is characterized by episodes of interrupted or obstructed bile flow from the liver (cholestasis), resulting from inflammation, thickening, and/or abnormal formation of fibrous tissue (fibrosis) within the passages that carry bile from the liver (bile ducts).
		In addition, primary sclerosing cholangitis may progress to cause scarring and damage to the liver (cirrhosis) and increased blood pressure in the veins carrying blood from the gastrointestinal (GI) tract back to the heart through the liver (portal hypertension).
	www.cigna.com /healthinfo/nord418.html (1355 words)

	Primary sclerosing cholangitis - Wikipedia, the free encyclopedia
		Primary sclerosing cholangitis (PSC) is an inflammatory disease of the bile duct, which leads to cholestasis (blockage of bile transport to the gut).
		Ascending cholangitis, or infection of the bile duct.
		PSC is associated with cholangiocarcinoma, which are tumors involving the biliary tree.
	en.wikipedia.org /wiki/Primary_sclerosing_cholangitis (650 words)

	PRIMARY SCLEROSING CHOLANGITIS / Liver Disease - Articles
		Primary sclerosing cholangitis is a disease in which the bile ducts inside and outside the liver become narrowed due to inflammation and scarring.
		Primary sclerosing cholangitis has been considered a rare disease, but recent studies suggest that it is more common than previously thought.
		The various symptoms of primary sclerosing cholangitis often respond effectively to medications that control itching, antibiotics when recurrent infections occur, and vitamins to replace those that are deficient.
	www.illness-disease.com /rec/295-PRIMARY-SCLEROSING-CHOLANGITIS (508 words)

	Primary Sclerosing Cholangitis and Primary Biliary Cirrhosis - Patients - American College of Gastroenterology
		Primary sclerosing cholangitis (PSC) is an uncommon, chronic disorder that involves scarring and inflammation of the large bile ducts of the liver.
		In PSC, the bile ducts both within and outside of the liver may have areas of narrowing (strictures) and dilatations producing a beaded appearance that is characteristic of this disease.
		Primary Biliary Cirrhosis (PBC) is a chronic liver disease that is characterized by inflammation and destruction of the bile ducts.
	www.acg.gi.org /patients/gihealth/sclerosing.asp (2458 words)

	Slcerosing Cholangitis
		By Howard J. Worman, M. Primary sclerosing cholangitis (PSC) is a chronic liver disease characterized by inflammation, destruction and fibrosis of the intrahepatic and extrahepatic bile ducts that leads to cirrhosis of the liver.
		PSC is often complicated by recurrent episodes of bacterial cholangitis (infection of the bile ducts with bacteria).
		PSC is a progressive disease that leads to cirrhosis and liver failure.
	cpmcnet.columbia.edu /dept/gi/PSC.html (947 words)

	Canadian Liver Foundation \| Primary Sclerosing Cholangitis
		Primary sclerosing cholangitis is a liver disease in which the bile ducts (small tubes through which bile flows from the liver to the gall bladder and intestines) progressively decrease in size due to inflammation and scarring.
		Although primary sclerosing cholangitis has been considered a rare disease, recent studies suggest that it is more common than originally thought.
		Primary sclerosing cholangitis affects both sexes, but is more common in men.
	www.liver.ca /Liver_Disease/Adult_Liver_Diseases/Primary_Sclerosing_Cholangitis.aspx (349 words)

	Primary Sclerosing Cholangitis
		Primary sclerosing cholangitis is another diseases which induces alkaline phosphatase.
		This disease differs from primary biliary cirrhosis in that the large bile ducts, the extra hepatic biliary tree are affected.
		Patients with primary sclerosing cholangitis have problems associated with strictures in the large bile ducts.
	www.gastromd.com /education/primarysclerosingcholangitis.html (262 words)

	Primary Sclerosing Cholangitis - HIV: health and medical information about HIV and AIDS
		Primary sclerosing cholangitis (PSC) is a chronic disorder of the liver in which the bile ducts outside the liver (the extrahepatic bile ducts) and often the bile ducts inside the liver (the intrahepatic bile ducts) become inflamed, thickened (sclerotic), narrowed, and finally obstructed.
		As PSC progresses, the disease causes cirrhosis of the liver (irreversible scarring of the liver) and liver failure, leading to the consideration of liver transplantation.
		The diagnosis of PSC is suspected from the symptoms and signs and abnormal laboratory tests and then is confirmed by demonstration of thickened bile ducts using a special radiological test called cholangiography in which dye is injected into the bile ducts and then x-rays are taken of the injected ducts.
	www.medicinenet.com /primary_sclerosing_cholangitis/article.htm (662 words)

	Primary sclerosing cholangitis - WrongDiagnosis.com
		Misdiagnosis of Underlying Causes of Primary sclerosing cholangitis
		Primary sclerosing cholangitis: A rare progressive disorder involving inflammation and fibrosis of the bile ducts which carry bile from the liver.
		Primary sclerosing cholangitis is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH).
	www.wrongdiagnosis.com /p/primary_sclerosing_cholangitis/intro.htm (514 words)

	Primary Sclerosing Cholangitis - Diagnosis and Treatment Options at Mayo Clinic
		Primary sclerosing cholangitis is a disease in which the ducts inside and outside the liver are narrowed due to inflammation.
		PSC most often affects people in their 30s to 50s; the average age at diagnosis is 40.
		The cause of PSC is unknown, but it is thought to be an immune response in which the body attacks the cells lining the bile ducts of the liver.
	www.mayoclinic.org /primary-sclerosing-cholangitis (538 words)

	Primary Sclerosing Cholangitis (PSC) - Patient UK
		The term primary is used to distinguish this condition from bile duct strictures that are secondary to bile duct injury, cholelithiasis or ischaemia.
		Patients with PSC and ulcerative colitis have an increased risk of colorectal cancer.
		MacFaul GR, Chapman RW; Sclerosing cholangitis.; Curr Opin Gastroenterol.
	www.patient.co.uk /showdoc/40002280 (1967 words)

	Primary Sclerosing Cholangitis (PSC)
		Primary sclerosing cholangitis is a disease primarily of the bile ducts, both inside and outside the liver.
		PSC often starts between the ages of 30 and 50, and it occurs most often in men.
		Primary sclerosing cholangitis is a slow, progressive disease.
	www.gicare.com /pated/ecdlv35.htm (1096 words)

	Primary Sclerosing Cholangitis (PSC): Gallbladder and Bile Duct Disorders: Merck Manual Professional
		Primary sclerosing cholangitis is a chronic cholestatic syndrome characterized by patchy inflammation, fibrosis, and strictures of the intrahepatic and extrahepatic bile ducts.
		However, primary sclerosing cholangitis (PSC) is strongly associated with inflammatory bowel disease, occurring in about 5% of patients with ulcerative colitis and in about 1% with Crohn's disease.
		Sclerosing cholangitis in HIV‑infected patients may be due to cryptosporidiosis or cytomegalovirus.
	www.merck.com /mmpe/sec03/ch030/ch030f.html (733 words)

	Primary Sclerosing Cholangitis (PSC): Fatty Liver, Cirrhosis, and Related Disorders: Merck Manual Home Edition
		Primary sclerosing cholangitis is inflammation and eventual scarring and obstruction of the bile ducts inside and outside the liver.
		It differs from primary biliary cirrhosis because the bile ducts both inside and outside the liver are affected.
		Primary sclerosing cholangitis may require liver transplantation (see Transplantation: Liver Transplantation), which is the only known cure for this otherwise fatal disorder.
	www.merck.com /mmhe/sec10/ch136/ch136e.html (540 words)

	Primary Sclerosing Cholangitis (Site not responding. Last check: 2007-10-23)
		PSC appears to be associated with ulcerative colitis, a type of inflammatory bowel disease.
		PSC is diagnosed through cholangiography, which involves injecting dye into the bile ducts and taking an x ray.
		Treatment includes medication to relieve itching, antibiotics to treat infections, and vitamin supplements, as people with PSC are often deficient in vitamins A, D, and K. In some cases, surgery to open major blockages in the common bile duct is also necessary.
	digestive.niddk.nih.gov /ddiseases/pubs/primarysclerosingcholangitis (524 words)

	eMedicine - Primary Sclerosing Cholangitis : Article by Lynette Gillis, MD
		Background: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown etiology that is recognized increasingly in children.
		The biliary injury may be initiated by an immune-mediated destruction of the hepatobiliary tract that is perhaps caused by transient infection or the absorption of bacterial byproducts in genetically predisposed individuals with colonic disease.
		PSC is characterized by a slow insidious progression to cirrhosis.
	www.emedicine.com /ped/topic1895.htm (3387 words)

	Course and Complications of Ulcerative Colitis
		Ulcerative colitis has a significant association with primary sclerosing cholangitis (PSC), a progressive inflammatory disorder of small and large bile ducts.
		As many as 5% of patients with ulcerative colitis may progress to develop primary sclerosing cholangitis.
		The effect of ulcerative colitis on mortality is unclear, but it is thought that the disease primarily affects quality of life, and not lifespan.
	www.colitisinfo.org /course-complications (192 words)

	PSC Partners Seeking a Cure Foundation: HomePage/Mission
		PSC Partners Seeking a Cure is a foundation that endeavors to find a cure for Primary Sclerosing Cholangitis.
		PSC is affecting the lives of too many people including young children, college students, mothers, fathers, and grandparents.
		PSC Partners Seeking a Cure has recently donated $20,000 to support the STOPSC research initiative of the Morgan Foundation; see press release from Memphis Business News, Jan 8, 2007.
	www.pscpartners.org (501 words)

	CHRIS KLUG, OLYMPIAN: PRIMARY SCLEROSING CHOLANGITIS
		Your liver is supposed to remove breakdown products of metabolism from your bloodstream, concentrate them into liquid called bile, which is supposed to travel along special ducts to be stored in your gall bladder.
		Klug knew that his hero, Walter Payton, the great running back for the Chicago Bears Football Team had primary sclerosing cholangitis and in 1999, died at age 45 of bile duct cancer.
		I was under the impression that Primary Sclerosing Cholangitis patients didn't die, and I was scared to death.
	www.drmirkin.com /fitness/9891.html (707 words)

	NEJM -- Primary Sclerosing Cholangitis
		Drewe, E., Zaitoun, A. M., Walker, D. A., Mukherjee, S. Case 11-2003: Ulcerative Colitis and Primary Sclerosing Cholangitis in a 14-Year-Old Boy.
		Bader, T. R., Beavers, K. L., Semelka, R. MR Imaging Features of Primary Sclerosing Cholangitis: Patterns of Cirrhosis in Relationship to Clinical Severity of Disease.
		K-ras mutations in the bile of patients with primary sclerosing cholangitis.
	content.nejm.org /cgi/content/short/332/14/924 (534 words)

	Primary sclerosing cholangitis - MayoClinic.com (Site not responding. Last check: 2007-10-23)
		Primary sclerosing cholangitis (PSC) is a condition in which the bile ducts — both inside and outside of the liver — may become inflamed and eventually obstructed.
		PSC most often occurs in men and may be associated with inflammatory bowel disease.
		In this procedure, an X-ray is taken after dye is injected into the bile ducts.
	www.mayoclinic.com /health/primary-sclerosing-cholangitis/AN01009 (204 words)

	Liver Disease in Saudi Arabia - Liver Diseases - Sclerosing Cholangitis
		Liver Disease in Saudi Arabia - Liver Diseases - Sclerosing Cholangitis
		Itching, jaundice-yellowing of the skin and whites of the eyes, episodes of fever, shaking and chills.
		Antibiotics to treat infections, and vitamin supplements, as people with PSC are often deficient in vitamins A, D, and K. In some cases, surgery to open major blockages in the common bile duct is also necessary.
	www.liverme.org /liver_diseases/sclerosing_cholangitis.htm (174 words)

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