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Topic: Progressive multifocal leukoencephalopathy


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 Progressive multifocal leukoencephalopathy - Wikipedia, the free encyclopedia
Progressive multifocal leukoencephalopathy (PML), also known as progressive multifocal leukoencephalitis, is a rare and usually fatal viral disease that is characterized by progressive damage (-pathy) or inflammation (-itis) of the white matter (leuko-) of the brain (-encephalo-) at multiple locations (multifocal).
The cause of PML is a type of polyomavirus called the JC virus (JCV), after the initials of the patient in whom it was first discovered.
Berger, J.R. (2003) Progressive multifocal leukoencephalopathy in acquired immunodeficiency syndrome: explaining the high incidence and disproportionate frequency of the illness relative to other immunosuppressive conditions.
en.wikipedia.org /wiki/Progressive_multifocal_leukoencephalopathy   (608 words)

  
 Progressive Multifocal Leukoencephalopathy
The detection and semiquantitation of JC virus (JCV) DNA in cerebrospinal fluid (CSF) is prognostic of survival and is a marker of the course of progressive multifocal leukoencephalopathy (PML).
PML was the presenting manifestation of AIDS in 5 (71.4%) of 7 long-term survivors compared with 8 (17.8%) of 45 short-term survivors.
Progressive multifocal leukoencephalopathy (PML), a frequently fatal demyelinating disease caused by JC virus, occurs as an opportunistic infection in patients with acquired immunodeficiency syndrome.
www.thedoctorsdoctor.com /diseases/pml.htm   (6283 words)

  
 Progressive multifocal leukoencephalopathy   (Site not responding. Last check: 2007-10-08)
Progressive multifocal leukoencephalopathy (PML) is a rare, usually fatal demyelinating disease of the brain caused by the JC virus (JCV).
PML may be suspected when computed tomography or magnetic resonance imaging demonstrates multiple areas of cerebral white matter demyelination.
PML is a progressive, usually lethal demyelinating disease due to infection by JCV.
www.ccm.lsuhsc-s.edu /BugBytes/Volume2/bb-v2n10.htm   (463 words)

  
 Viral Infections: Progressive Multifocal Leukoencephalopathy (PML)
PML is a rare neurological disease believed to be caused by reactivation of latent JCV infection, resulting in demyefination of the central nervous system.
PML does not appear to be contagious, and the primary infection probably occurs in childhood.
Progressive multifocal leukoencephalopathy: disease progression, stabilization and response to intrathecal ARA-C in 26 patients.
www.hivpositive.com /f-Oi/OppInfections/4-Viral/4-Vir-PML.html   (480 words)

  
 SF AIDS Fdn: BETA 9/97 -- Progressive Multifocal Leukoencephalopathy
PML is rarely found in early HIV disease; when it does occur, it is almost always found in people with late-stage HIV disease.
PML is progressive in that there is continuous expansion of brain lesions caused by the JC virus.
PML lesions typically begin at the junction between the grey matter and the underlying white matter of the brain.
www.sfaf.org /treatment/beta/b34/b34pml.html   (3473 words)

  
 Progressive Multifocal Leukoencephalopathy | AHealthyMe.com
Progressive multifocal leukoencephalopathy (PML) is a rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells (oligodendrocytes and astrocytes) by the JC virus (JCV).
PML is an opportunistic infection associated with AIDS and certain cancers.
In PML, the JCV infects and kills the cells (oligodendrocytes) that produce myelin, which is needed to form the sheath that surrounds and protects nerves.
www.ahealthyme.com /topic/topic100587348   (544 words)

  
 AidsPortugal - Progressive Multifocal leukoencephalopathy   (Site not responding. Last check: 2007-10-08)
Progressive multifocal leukoencephalopathy (PML) is a fatal, demyelinating disease caused by JC virus (JCV) in patients with severe immunosuppression.
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by a reactivation of the polyomavirus JC (JCV) within a setting of immunosuppression.
PML was confirmed by clinical symptoms, measurable MRI lesions, and brain biopsy or CSF JC virus PCR; HIV was confirmed by serology.
www.aidsportugal.com /article.php?sid=606   (2580 words)

  
 Progressive Multifocal Leukoencephalopathy Information Page: National Institute of Neurological Disorders and Stroke ...
Progressive multifocal leukoencephalopathy (PML) is an infrequent disorder of the nervous system that primarily affects individuals with suppressed immune systems (including, allograft recipients such as kidney transplant patients; patients with cancers such as leukemia or lymphoma; and nearly 10% of patients with acquired immune deficiency syndrome — AIDS.
The disorder, which is caused by a common human polyomavirus, JC virus, is characterized by demyelination or destruction of the myelin sheath that covers nerve cells.
Symptoms of PML include mental deterioration, vision loss, speech disturbances, ataxia (inability to coordinate movements), paralysis, and, ultimately, coma reflecting the multifocal distribution of brain lesions.
www.ninds.nih.gov /disorders/pml/pml.htm   (346 words)

  
 Progressive Multifocal Leukoencephalopathy
Progressive multifocal leukoencephalopathy (PML) is a rare disorder of the nervous system that primarily affects individuals with suppressed immune systems -- such as patients with cancers leukemia, lymphoma, or acquired immune deficiency syndrome (AIDS).
The disorder, which is caused by a virus, is characterized by demyelination or destruction of the myelin sheath that covers nerve cells.
Symptoms of PML include mental deterioration, vision loss, speech disturbances, ataxia (inability to coordinate movements), paralysis, and, ultimately, coma.
healthlink.mcw.edu /article/921450160.html   (168 words)

  
 [Progressive multifocal leukoencephalopathy]
Progressive multifocal leucoencephalopathy (PML) is a rarely occurring demyelinating disease of the central nervous system caused by a neurotropic papovavirus named JC virus (JCV).
The course of the disease is still most often rapidly progressive and fatal, but several cases with prolonged survival and even remission have been reported, and various antiviral treatments have been tried.
Suspicion of PML should lead to an extensive immunological investigation before considering of brain biopsy, which is still the only specific test.
www.aegis.com /aidsline/1995/may/M9550624.html   (471 words)

  
 Progressive multifocal leukoencephalopathy (PML) : Epilepsy.com/Professionals
Progressive multifocal leukoencephalopathy (PML) is a subacute demyelinating disease caused by an opportunistic papovavirus, usually the Jamestown Canyon strain.
PML is characterized by the presence of multiple (in part confluent) areas of CNS demyelination, primarily in subcortical white matter.
As the disease progresses, the demyelinated plaques coalesce to form large lesions.
professionals.epilepsy.com /page/infectious_pml.html   (240 words)

  
 Progressive Multifocal Leucoencephalopathy (PML) | The New Mexico Aids Info Net
Progressive multifocal leucoencephalopathy is a serious viral infection of the brain.
PML can be diagnosed using a scan of the brain by magnetic resonance imaging (MRI).
PML is a viral infection of the brain.
www.aidsinfonet.org /articles.php?articleID=516&newLang=en   (730 words)

  
 OI: PML -- ÆGIS
PML is caused by the JC virus (JCV).
PML is generally a "late stage" disease that shows up only with a severely damaged immune system.
Once PML begins, it is usually quite aggressive and fatal.
www.aegis.com /topics/oi/oi-pml.html   (321 words)

  
 MedlinePlus Medical Encyclopedia: Progressive multifocal leukoencephalopathy
PML is a rare inflammatory disorder that leads to loss of myelin in multiple areas within the white matter of the brain.
It is a virus-induced disease seen in people with poor immune function (immunocompromised).
Symptoms and signs include loss of coordination, clumsiness, memory loss, progressively worsening weakness of the legs, and to a lesser extent, arms.
www.nlm.nih.gov /medlineplus/ency/article/000674.htm   (265 words)

  
 Crohn's Disease therapy: Natalizumab and progressive multifocal leukoencephalopathy   (Site not responding. Last check: 2007-10-08)
Adelman, B., Sandrock, A., Panzara, M. Natalizumab and Progressive Multifocal Leukoencephalopathy.
Berger, J. R., Koralnik, I. Progressive Multifocal Leukoencephalopathy and Natalizumab -- Unforeseen Consequences.
Kleinschmidt-DeMasters, B.K., Tyler, K. Progressive Multifocal Leukoencephalopathy Complicating Treatment with Natalizumab and Interferon Beta-1a for Multiple Sclerosis.
content.nejm.org /cgi/content/short/353/4/362   (544 words)

  
 The Body: PML (Progressive Multifocal Leukoencephalopathy)
Progressive Multifocal Leukoencephalopathy (PML) Fact Sheet (September 2000)
Clinical and Virological Correlates of Longer Survival in AIDS-Associated Progressive Multifocal Leukoencephalopathy (January 31, 2000)
The Molecular Pathogenesis of Progressive Multifocal Leukoencephalopathy (February 3, 1998)
www.thebody.com /treat/neuro_pml.html   (241 words)

  
 Progressive Multifocal Leukoencephalopathy and multiple sclerosis treatment complications   (Site not responding. Last check: 2007-10-08)
Progressive Multifocal Leukoencephalopathy and multiple sclerosis treatment complications
Progressive Multifocal Leukoencephalopathy Complicating Treatment with Natalizumab and Interferon Beta-1a for Multiple Sclerosis
PML was diagnosed on the basis of the
content.nejm.org /cgi/content/short/353/4/369   (482 words)

  
 Gale Encyclopedia of Medicine: Progressive multifocal leukoencephalopathy   (Site not responding. Last check: 2007-10-08)
Save a personal copy of this article and quickly find it again with Furl.net.
"Progressive Multifocal Leukoencephalopathy." In Harrison's Principles of Internal Medicine, edited by Kurt J. Isselbacher et al.
"Update on Progressive Multifocal Leukoencephalopathy." The Hopkins HIV Report, 9 (March 1997).
www.findarticles.com /p/articles/mi_g2601/is_0011/ai_2601001116   (595 words)

  
 PML - Progressive multifocal leukoencephalopathy Information
If you have developed PML due to Tysabri use, please fill out this simple form to contact Weitz and Luxenberg for a free case evaluation.
Have you been diagnosed with progressive multifocal leukoencephalopathy (PML)?
Tysabri, PML and Avonex from sources such as the FDA - Learn More
www.weitzlux.com /tysabripmlavonex/pml_1917.html   (398 words)

  
 Dr. Koop - Progressive multifocal leukoencephalopathy
Home > Health Reference > Progressive multifocal leukoencephalopathy
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition.
You should promptly seek professional medical care if you have any concern about your health, and you should always consult your physician before starting a fitness regimen.
www.drkoop.com /ency/1/000674trt.html   (164 words)

  
 Progressive Multifocal Leukoencephalopathy
Progressive Multifocal Leukoencephalopathy Information Page National Institute of Neurological Disorders and Stroke
Progressive Multifocal Leukoencephalopathy (PML) New Mexico AIDS InfoNet (also in Spanish)
All medical information needs to be carefully reviewed with your health care provider.
www.noah-health.org /en/bns/disorders/other/progresleuko.html   (100 words)

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