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Topic: Promethazine

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	Promethazine (PIM 439)
		Promethazine is metabolized principally to promethazine sulphoxide and to a lesser degree desmethylpromethazine.
		Promethazine rapidly crosses the blood brain barrier and it is thought that the sedative effects of antihistamines are due to blockade of H1 receptors in the brain (Quach et al., 1979).
		Promethazine is unstable in aqueous and organic solvents (Meaking et al., 1978) and, due to its large volume of distribution, is present in very low concentrations in body fluids.
	www.inchem.org /documents/pims/pharm/prometha.htm (6795 words)

	Parkinsn's List Drug DataBase promethazine HCL / Phenegran
		Although promethazine is classified as a phenothiazine, its ability to antagonize dopamine is approximately one-tenth that of chlorpromazine.
		Promethazine is classified as pregnancy category C. Antihistamines generally are not recommended for use in pregnancy, especially during the third trimester, because there is a risk of seizures in the fetus, although promethazine may be used as a sedative during labor.
		Promethazine is extensively metabolized in the liver, hepatic impairment may lead to a decrease in metabolism, a subsequent increase in drug levels, and an added risk of toxicity.
	www.parkinsons-information-exchange-network-online.com /drugdb/110.html (2347 words)

	Promethazine - Wikipedia, the free encyclopedia
		Promethazine is a first-generation H1 receptor antagonist antihistamine and antiemetic medication.
		Previously it was used as an antipsychotic, although it is generally not administered for this purpose now; promethazine has only approximately 1/10 of the antipsychotic strength of chlorpromazine.
		Promethazine should not be given to children under two years of age; there is potential for fatal respiratory depression in this age group.
	en.wikipedia.org /wiki/Promethazine (422 words)

	Drug Profiles: Phenergan® for Migraines
		Promethazine is a phenothiazine however it is not used clinically as a neuroleptic.
		Promethazine is a versatile drug but is used predominantly as an antiemetic or to prevent motion sickness.
		Promethazine is administered orally, rectally, intramuscularly, and intravenously.
	www.migraines.org /treatment/prophnrg.htm (491 words)

	MedlinePlus Drug Information: Promethazine
		Promethazine should not be given to babies or children who are younger than 2 years old and should be given with caution to children who are 2 years of age or older.
		Promethazine is used to relieve the symptoms of allergic reactions such as allergic rhinitis (runny nose and watery eyes caused by allergy to pollen, mold or dust), allergic conjunctivitis (red, watery eyes caused by allergies), allergic skin reactions, and allergic reactions to blood or plasma products.
		Promethazine comes as a tablet and syrup (liquid) to take by mouth and as a suppository to use rectally.When promethazine is used to treat allergies, it is usually taken one to four times daily, before meals and/or at bedtime.
	www.nlm.nih.gov /medlineplus/druginfo/medmaster/a682284.html (1330 words)

	Promethazine Information on Healthline
		Promethazine oral should not be given to a child younger than 2 years old.
		Promethazine oral is used to treat allergy symptoms such as itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes.
		Promethazine oral also prevents motion sickness, and treats nausea and vomiting or pain after surgery.
	www.healthline.com /multumcontent/promethazine (801 words)

	Phenergan Indications, Dosage, Storage, Stability - Promethazine - RxList Monographs
		If necessary, promethazine HCl with a reduced dose of analgesic may be repeated once or twice at four-hour intervals in the course of a normal labor.
		The average effective dose of promethazine HCl for the active therapy of nausea and vomiting in children or adults is 25 mg.
		Usual adult dosage is 50 mg promethazine HCl with an equal amount of meperidine and the required amount of a belladonna alkaloid.
	www.rxlist.com /cgi/generic/prometh_ids.htm (1384 words)

	Howstuffworks "Promethazine: A Profile of an Antihistamine"
		Promethazine, a phenothiazine derivative, is prescribed for a wide range of conditions.
		Promethazine also (1) works at the vomiting center in the brain and can be used for the prevention or treatment of nausea and vomiting; (2) is a central nervous system (brain and spinal cord) depressant, which produces light sleep or mild sedation; and (3) prevents motion sickness.
		Promethazine can cause extreme drowsiness when combined with alcohol or other central nervous system depressants (drugs that slow the activity of the brain and spinal cord), such as barbiturates, benzodiazepine tranquilizers, muscle relaxants, narcotics, and pain medications, or with tricyclic antidepressants.
	health.howstuffworks.com /define-promethazine.htm (1052 words)

	Consumer Reports Medical Guide - Promethazine
		Promethazine should not routinely be used to treat vomiting in children; it should only be used in specific cases when a doctor decides that it is needed.
		Promethazine is also used to prevent and control upset stomach and vomiting that may occur after surgery, and to help relieve pain after surgery.
		If you are giving promethazine to a child, watch the child to be sure he or she does not get hurt while riding a bike or participating in other activities that could be dangerous.
	www.consumerreports.org /mg/drug-reports/promethazine.htm (1450 words)

	ACS :: Cancer Drug Guide: promethazine hydrochloride
		Promethazine hydrochloride belongs to a general class of antinausea drugs called antihistamines.
		Promethazine hydrochloride is given as a pill or liquid by mouth, as a rectal suppository, or as an injection in a vein over 5 minutes or in a muscle.
		Promethazine hydrochloride may cause increased risk of confusion, sedation, and drowsiness in the elderly.
	www.cancer.org /docroot/CDG/content/CDG_promethazine_hydrochloride.asp (507 words)

	promethazine, Phenergan - drug class, medical uses, medication side effects, and drug interactions by MedicineNet.com
		Promethazine should not be used in children less than two years of age because it can depress respiration and has caused fatalities in children under two. It should be used cautiously in children older than two.
		Promethazine should not be used with propylthiouracil (PTU) due to the increased risk of dangerous drops in the white blood cell count which can increase the risk of infections.
		Promethazine should be stopped at least 48 hours before myelography and not restarted until at least 24 hours after myelography.
	www.medicinenet.com /promethazine/article.htm (800 words)

	Promethazine (marketed as Phenergan): Patient Information Sheet
		Promethazine is an antihistamine which can be taken by mouth as a tablet or syrup, rectally as a suppository, or by injection.
		Promethazine should not be used in patients with poor lung function such as chronic obstructive lung disease or breathing problems while sleeping (sleep apnea).
		Promethazine should be used with caution in patients with seizures or who are on other medicines which may also increase the risk of seizures.
	www.fda.gov /cder/drug/InfoSheets/patient/promethazinePIS.htm (666 words)

	codeine and promethazine - [Medication]
		Promethazine is used alone to treat allergic symptoms and reactions such as itchy, runny nose; sneezing; itchy, watery eyes; and hives or itchy skin rashes.
		Promethazine is also used to cause sedation (sleep), to assist in controlling postoperative pain, to control nausea and vomiting (especially after surgery), and to prevent motion sickness.
		Codeine and promethazine is used to treat coughs and other respiratory and nasal symptoms of allergies and the common cold.
	www.peacehealth.org /kbase/multum/d03357a1.htm (1447 words)

	Antihistamine promethazine: Warning for kids under 2 - MayoClinic.com (Site not responding. Last check: 2007-09-11)
		Federal health officials are warning parents and doctors not to give medications containing the antihistamine promethazine, marketed as Phenergan, to children younger than 2 years old.
		Promethazine is a prescription antihistamine commonly used to treat allergy signs and symptoms, such as a stuffy or runny nose.
		Promethazine is not safe for children younger than age 2.
	www.mayoclinic.com /health/promethazine/DI00064 (252 words)

	[No title]
		Promethazine is an antihistamine that is used for allergy relief, mild sedation, prevention and control of nausea. If you or your child is on Promethazine (Phenergan®, Promacot®, Promethegan®, Promethazine HCI syrup® and generic products) or if you are considering the use of Promethazine, please read the FDA information provided below.
		Promethazine may cause drowsiness which may impair your ability to ride a bike, drive a car, or operate machinery. This may be worsened if taken with alcohol or other drugs that also cause central nervous system (CNS) slowing such as sedatives, pain medicines, tranquilizers or certain drugs for depression.
		Increased risk of seizures. ; Promethazine should be used with caution in patients with seizures or who are on other medicines which may also increase the risk of seizures.
	www.pritzkerlaw.com /Promethazine (873 words)

	Phenergan Online, Description, Chemistry, Ingredients - Promethazine - RxList Monographs
		Promethazine hydrochloride is a racemic compound; the empirical formula is C
		Promethazine hydrochloride occurs as a white to faint yellow, practically odorless, crystalline powder which slowly oxidizes and turns blue on prolonged exposure to air.
		Each rectal suppository of Phenergan contains 12.5 mg, 25 mg, or 50 mg promethazine hydrochloride with ascorbyl palmitate, silicon dioxide, white wax, and cocoa butter.
	www.rxlist.com /cgi/generic/prometh.htm (344 words)

	NASA - Exploration Systems - Bioavailability and Performance Effects of Promethazine During Space Flight (PMZ) (Site not responding. Last check: 2007-09-11)
		Promethazine is a motion sickness medication taken by the Space Shuttle astronauts.
		Promethazine (PMZ) is used to treat space motion sickness (SMS) during Shuttle missions.
		Promethazine (PMZ) is a drug that is used for the treatment of space motion sickness for the Space Shuttle astronauts.
	exploration.nasa.gov /programs/station/PMZ_lite.html (640 words)

	Promethazine - Patient UK
		Promethazine is used to relieve allergies such as skin rashes, itching and symptoms of hayfever.
		Promethazine can also be used to treat sickness, vertigo (loss of balance or dizziness), travel sickness and problems affecting the inner ear and balance.
		Promethazine is available in tablet, oral liquid and injection form.
	www.patient.co.uk /showdoc/30002738 (666 words)

	Promethazine - FLORIDA RX - Online prescriptions source for Florida
		Pregnancy-Methdilazine, promethazine, and trimeprazine have not been studied in pregnant women.
		In animal studies, promethazine has not been shown to cause birth defects.
		Also, the newborn baby may have blood clotting problems if promethazine is taken by the mother within 2 weeks before delivery.
	www.florida-rx.com /promethazine.html (2928 words)

	dextromethorphan and promethazine - Drug Finder - MSN Health & Fitness (Site not responding. Last check: 2007-09-11)
		Dextromethorphan and promethazine is used to treat coughs; runny nose; sneezing; and congestion associated with allergies or the common cold.
		Dextromethorphan and promethazine is in the FDA pregnancy category C. This means that it is not known whether dextromethorphan and promethazine will harm an unborn baby.
		Dextromethorphan and promethazine is available with a prescription generically and under the brand name Phenergan with dextromethorphan.
	health.msn.com /drugfinder/articlepage.aspx?cp-documentid=100106834 (1192 words)

	Promethazine HCI (marketed as Phenergan) Information
		Medications containing promethazine hydrochloride (HCl) should not be used for children less than two years of age because of the potential for fatal respiratory depression.
		Cases of respiratory depression including fatalities have been reported with use of promethazine HCl in children less than two years of age.
		Caution should also be exercised when administering promethazine HCl in any form to pediatric patients two years of age and older.
	www.fda.gov /cder/drug/infopage/promethazine/default.htm (176 words)

	Promethazine (Site not responding. Last check: 2007-09-11)
		Promethazine is an antihistamine used to relieve allergic rhinitis (seasonal allergy) symptoms including sneezing, runny nose, itching, and watery eyes and itching and swelling associated with uncomplicated allergic skin reactions.
		Promethazine is available as a nonprescription product alone and in a combination product to treat symptoms of allergy, colds, and upper respiratory infections.
		It is also available in prescription products with codeine, to treat coughs associated with colds and upper respiratory infections.
	www.kroger.com /hn/Drug/Promethazine.htm (396 words)

	promethazine
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	promethazine.cheap-tabs.info (2621 words)

	Promethazine
		This medicine is used to prevent or treat motion sickness and nausea/vomiting (from various causes).
		Promethazine works in preventing or decreasing hormone (dopamine) effects on the brain's vomiting center.
		By decreasing dopamine's effect on the vomiting center, nausea and vomiting are prevented, decreased, or stopped.
	www.umm.edu /altmed/ConsDrugs/Promethazinecd.html (559 words)

	codeine and promethazine
		You may not be able to take codeine and promethazine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.
		Codeine and promethazine may increase the sensitivity of your skin to sunlight.
		Codeine and promethazine is available with a prescription under the brand name Phenergan with Codeine.
	hw.healthdialog.com /kbase/multum/d03357a1.htm (1595 words)

	promethazine Side Effects, Interactions and Information - Drugs.com
		Promethazine oral can cause side effects that may impair your thinking or reactions.
		To be sure you get the correct dose of promethazine oral syrup, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon.
		Your pharmacist has more information about promethazine oral written for health professionals that you may read.
	www.drugs.com /Promethazine/index.html (1515 words)

	promethazine side effects (Site not responding. Last check: 2007-09-11)
		Promethazine is used to treat allergic symptoms and reactions such as itching, runny nose; sneezing; itchy, watery eyes; hives; and itchy skin rashes.
		Promethazine is in the FDA pregnancy category C. This means that it is not known whether promethazine will harm an unborn baby.
		Promethazine may increase the sensitivity of your skin to sunlight.
	www.medicationadvisor.com /side_effects/promethazine.htm (1351 words)

	Use of Promethazine with Cough Syrup
		Abuse of promethazine with codeine is increasing at an exponential rate.
		The drug Promethazine with Codeine is commonly known "on the street" as "syrup" and/or "lean," the latter due to the abusers’ propensity of having difficulty in standing up straight.
		A prescription for Promethazine with Codeine can also be checked by observing whether or not the presenter has symptoms consistent with the medication requested.
	www.tsbp.state.tx.us /Newsletter/Promethazine8.htm (691 words)

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