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| | Guidelines for Preventing Opportunistic Infections Among HIV-Infected Persons -- 2002 |
 | | Discontinuing primary prophylaxis among patients meeting these criteria is recommended because, apparently, prophylaxis adds limited disease prevention for MAC or for bacterial infections and because discontinuing drugs reduces pill burden, potential for drug toxicity, drug interactions, selection of drug-resistant pathogens, and cost. |
 | | However, the majority of HIV specialists recommend that antifungal prophylaxis not be used routinely to prevent cryptococcosis because of the relative infrequency of cryptococcal disease, lack of survival benefits associated with prophylaxis, possibility of drug interactions, potential antifungal drug resistance, and cost. |
 | | Prophylaxis with fluconazole or itraconazole should not be initiated during pregnancy because of the low incidence of cryptococcal disease, lack of a recommendation for primary prophylaxis against cryptococcosis among nonpregnant adults, and potential teratogenic effects of these drugs during pregnancy (DIII) (86,87). |
| www.cdc.gov /mmwr/preview/mmwrhtml/rr5108a1.htm (16459 words) |
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