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Topic: Prostaglandin and leukotriene metabolism

	Equine Feed Supplement Ingredients Glossary (Site not responding. Last check: 2007-10-30)
		Stimulates enzymes of the energy metabolism; involved in the synthesis of fatty acids*, cholesterol and protein.
		Has a beneficial influence on the prostaglandin and leukotriene metabolism alleviating circulatory problems, skin disease and inflammation.
		The beneficial effects of these plants is related their ability to provide precursors of the prostaglandins where enzymatic* conversion of linoleic acid to gama-linolenic acid is deficient.
	www.buyselect.com /reference/glossary.htm (0 words)

	The Effects of Ethanol and Acetaldehyde on the Metabolism of Prostaglandin E2 and Leukotriene B4 in Isolated Rat ...
		The Effects of Ethanol and Acetaldehyde on the Metabolism of Prostaglandin E2 and Leukotriene B4 in Isolated Rat Hepatocytes -- Hankin et al.
		on the metabolic inactivation of prostaglandins and leukotrienes.
		Murphy RC and Wheelan P (1997) Metabolism of leukotrienes in vitro and in vivo, in From SRS-A to Leukotrienes: The Dawning of a New Treatment (Dahlén SE and Holgate S, eds) Chapter 7, pp 101-120 Blackwell Science, London.
	jpet.aspetjournals.org /cgi/content/full/285/1/155 (0 words)

	Polyunsaturated Fat Metabolism
		The omega-6 fatty acids suppress the metabolism of the omega-3 fatty acids and vice versa, at the rate limiting step (cyclo-oxygenase) and they both suppress the metabolism of n-9 fatty acids.
		N-6 linoleic is converted to arachidonic acid and the potent aggregatory prostaglandin thromboxane A2 (in platelet membranes) and leukotriene B
		Thus diets rich in corn, safflower, sunflower and peanut oils all of which are high in n-6 and low in n-3 can lead to n-3 fatty acid deficiency, and a high ratio of n-6 to n-3 accentuates this deficiency (Connor AJCN 1999; 69: 827-8).
	www.healthyeatingclub.com /info/articles/fats-chol/fat-metabolism.htm (0 words)

	CMRO 13-7-1996-417 Prostaglandin and Leukotriene
		There is some evidence that the inflammatory process is, at least in part, influenced and caused by prostaglandins and leukotrienes.
		The leukotriene synthesis was markedly decreased in concentrations of 10
		The prostaglandin synthesis was not affected by 5-ASA (or PAS), as shown in Figures 1 and 2.
	www.priory.com /cmro/cmro1085.htm (0 words)

	Chemistry Portfolio - Syllabi - Chem 160B (Site not responding. Last check: 2007-10-30)
		The course can be considered to consist of three important and related areas: bioenergetics, the process by which organisms capture, use and transform energy; metabolic pathways, which can be subdivided into catabolic (degradative, oxidative) and anabolic (synthetic, reductive) pathways; and regulation, the process by which metabolism is controlled.
		Draw, at a minimum, one metabolic pathway for each of the major groups of macromolecules, and describe the "logic" underpinning the series of reactions.
		The group sessions are designed to help you master concepts involving metabolism so that you can apply knowledge gained in lecture to novel problem situations.
	www.csus.edu /portfolio/prog/chem/2Syllabi160b.stm (0 words)

	Pure Encapsulations (Site not responding. Last check: 2007-10-30)
		Glucosamine is a naturally occurring compound necessary for the synthesis of proteoglycans, the protein molecules responsible for giving cartilage its strength and resilience.
		Boswellia serrata is an Ayurvedic herb that has a long history of use for connective tissue and joint support.
		Boswellic acids, the active terpenoid constituents of boswellia, may maintain healthy 5–lipoxygenase enzyme activity and healthy leukotriene metabolism to promote joint comfort.
	www.purecaps.com /itemdy00.asp?T1=EDG2 (0 words)

	PainX by Biogenesis Nutraceuticals
		It is this property along with its ability to inhibit both the classical and alternative complement pathways that accounts for its anti-inflammatory properties.
		Studies show that curcumin inhibits leukotriene synthesis, platelet aggregation, neutrophil inflammatory response, blocks activation of NF Kappa B and promotes fibrinolysis.
		In one small study, consisting of 10 individuals, complaining of chronic muscular pain and discomfort, ginger relieved the pain and swelling in 100% of the individuals.
	www.rockwellnutrition.com /product.asp?itemid=716 (0 words)

	Effect of Peroxisome Proliferator-Activated Receptor alpha Activation on Leukotriene B4 Metabolism in Isolated Rat ...
		Latruffe N and Vamecq J (1997) Peroxisome proliferators and peroxisome proliferator activated receptors (PPARs) as regulators of lipid metabolism.
		Leier I, Muller M, Jedlitschky G and Keppler D (1992) Leukotriene uptake by hepatocytes and hepatoma cells.
		Murphy RC and Hankin JA (1999) Metabolism of leukotrienes and formation of new leukotriene structures, in Novel Inhibitors of Leukotrienes.
	jpet.aspetjournals.org /cgi/content/full/299/2/691 (0 words)

	Alibris: Prostaglandin
		Prostaglandin Synthetase Inhibitors: Their Effects on Physiological Functions and Pathological States; Sponsored Jointly by the Royal Society of Medic
		Prostaglandin Symposium of the Worcester Foundation for Experimental Biology, October 16-17, 1967; [proceedings]
		This volume is the proceedings of the 11th International Conference on Advances in Prostaglandin and Leukotriene Research: Basic Science and New Clinical Applications, held in Florence, Italy, on June 4-8, 2000, which continues the tradition of covering both basic and clinical aspects of prostaglandin and leukotriene research.
	www.alibris.com /search/books/subject/Prostaglandin (0 words)

	Pathway analysis (Site not responding. Last check: 2007-10-30)
		grisea genes potentially coding for enzymes in a variety of metabolic pathways were identified by homology to Saccharomyces cerevisiae genes defined by KEGG as encoding enzymes belonging to these pathways.
		By selecting a pathway and pressing "Submit" a list will be produced of M.
		grisea ORFs that potentially encode the enzymes in this metabolic pathway - based on the yeast gene they are most similar to from the S.
	www.dcs.ex.ac.uk /~hmw203/mgrisea/pathway.html (0 words)

	RGD Gene Report: Alox5 (RGD: 2096)
		catalyzes the conversion of arachidonate to leukotriene A4 Gene Ontology
		lipoxygenase mediated pathway of arachidonic acid metabolism, leukotriene metabolic pathway, prostaglandin and leukotriene metabolic pathway (details...)
		RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.
	rgd.mcw.edu /tools/genes/genes_view.cgi?id=2096 (0 words)

	RGD Gene Report: Alox15 (RGD: 70493)
		active in synthesis of bioactive prostagladins, thromboxanes and leukotrienes
		electron transport, negative regulation of cell volume, leukotriene metabolism...
		lipoxygenase mediated pathway of arachidonic acid metabolism, prostaglandin and leukotriene metabolic pathway (details...)
	rgd.mcw.edu /tools/genes/genes_view.cgi?id=70493 (0 words)

	Botany online: Basic Metabolism - Biosyntheses - Lipids
		Botany online: Basic Metabolism - Biosyntheses - Lipids
		The synthesis of an extensive group of plant lipids as well as compounds of a lipid nature start with isoprene.
		Numerous of the compounds generated this way cannot be counted among the primary metabolism.
	www.biologie.uni-hamburg.de /b-online/e19/19i.htm (0 words)

	Green Lipped Mussel - 200mg Capsules x 100 (Site not responding. Last check: 2007-10-30)
		It also contains Glucosamine and Chondroitin Sulphate which are important building blocks for joint cartilage, and may assist in the repair of joint structures.
		Green Lipped Mussel works by affecting the inflammatory pathway of prostaglandin and leukotriene metabolism and inhibits inflammatory responses.
		Caution should be taken for people that are allergic to shell fish.
	www.lifetimehealth.com /en/page.asp?E_Page=209561&product=384690 (0 words)

	Intravenous Ifosfamide/Mesna Is Associated with Depletion of Plasma Thiols without Depletion of Leukocyte Glutathione ...
		thiol status of proteins, reduction of ribonucleotides to deoxyribonucleotides, metabolism
		of leukotriene and prostaglandin, and conversion of methylglyoxal
		Deleve L. D., Kaplowitz N. Glutathione metabolism and its role in hepatotoxicity.
	clincancerres.aacrjournals.org /cgi/content/full/6/4/1314 (0 words)

	Biozon search engine
		A researcher might call up the structures of proteins related to cancer, then identify the genes that code for those proteins.
		Or, to take a more technical example, search for "3D structures of proteins that are involved in phosphorylation interactions and are part of the Prostaglandin and leukotriene metabolism pathway." The results returned are ranked, using a first-of-a-kind biological ranking system that resembles the methods implemented in Google.
		Beyond complex searches, Biozon also supports"fuzzy" searches that will find things similar to the search key.
	www.news.cornell.edu /Chronicle/05/3.17.05/Biozon_search.html (439 words)

	[No title]
		glycogen, trehalose) YFR015C: KEGG: ot00500 Metabolism; Carbohydrate Metabolism; Starch and sucrose metabolism GOBP: GO:0005977 glycogen metabolism GOMF: GO:0004373 glycogen (starch) synthase activity GOCC: GO:0005737 cytoplasm GO:0005739 mitochondrion MIPS: 01.05.01.03.02.01 glycogen biosynthesis 02.19 metabolism of energy reserves (e.g.
		glycogen, trehalose) YLR258W: KEGG: ot00500 Metabolism; Carbohydrate Metabolism; Starch and sucrose metabolism GOBP: GO:0005977 glycogen metabolism GOMF: GO:0004373 glycogen (starch) synthase activity GOCC: GO:0005737 cytoplasm MIPS: 01.05.01.03.02.01 glycogen biosynthesis 01.05.04 regulation of C-compound and carbohydrate utilization 02.19 metabolism of energy reserves (e.g.
		glycogen, trehalose) YGR032W: KEGG: ot00500 Metabolism; Carbohydrate Metabolism; Starch and sucrose metabolism GOBP: GO:0006075 beta-1,3 glucan biosynthesis GO:0007047 cell wall organization and biogenesis GOMF: GO:0003843 1,3-beta-glucan synthase activity GOCC: GO:0000148 1,3-beta-glucan synthase complex GO:0005628 prospore membrane GO:0030478 actin cap MIPS: 01.05.01.03.02 polysaccharide biosynthesis 02.19 metabolism of energy reserves (e.g.
	www.cs.princeton.edu /~chuttenh/genedump.txt (0 words)

	PATHWAY List (Site not responding. Last check: 2007-10-30)
		Synthesis and degradation of ketone bodies - Schizosaccharomyces pombe(2/2)
		Urea cycle and metabolism of amino groups - Schizosaccharomyces pombe(15/17)
		Glycine, serine and threonine metabolism - Schizosaccharomyces pombe(23/30)
	udgenome.ags.udel.edu /fungi/pathway/path.php (0 words)

	DrugBank: Masoprocol
		Although the exact mechanism of action is not known, studies have shown that masoprocol is a potent 5-lipoxygenase inhibitor and has antiproliferative activity against keratinocytes in tissue culture, but the relationship between this activity and its effectiveness in actinic keratoses is unknown.
		Masoprocol also inhibits prostaglandins but the significance of this action is not yet known.
		Symptoms of overdose or allergic reaction include bluish coloration of skin, dizziness, severe, or feeling faint, wheezing or trouble in breathing.
	redpoll.pharmacy.ualberta.ca /drugbank/cgi-bin/getCard.cgi?CARD=APRD01084 (0 words)

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