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Topic: Prostate specific antigen

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In the News (Wed 21 Aug 19)

  The Prostate Centre | Prostate Specific Antigen (PSA)
Prostate specific antigen (PSA) is an enzyme produced in the ducts of the prostate and absorbed into the bloodstream.
The PSA level that is considered normal for an average man ranges from 0 to 4 nanograms per milliliter (ng/ml).
A PSA level of 4 to 10 ng/ml is considered slightly elevated; levels between 10 and 20 ng/ml are considered moderately elevated; and anything greater is considered highly elevated.
www.prostatecentre.ca /diagnosis_psa.html   (195 words)

 [No title]
Prostate cancer is the most commonly diagnosed cancer in men in the United States and is tied for the second leading cause of cancer death for males.
Prostate cancer occurs mostly in older men, it is rare before the age of 50, and the risk increases with age.
Prostate tissue produces prostate specific antigen and prostatic acid phosphatase, an enzyme found in seminal fluid (the milky substance that combines with sperm to form semen).
www.lycos.com /info/prostate--prostate-specific-antigen.html   (677 words)

 eMedicine - Prostate-Specific Antigen : Article Excerpt by: Stanley A Brosman, MD
PSA evaluation was never intended to serve as a diagnostic test for prostate cancer but is useful in helping to identify men in whom a prostate biopsy would be appropriate.
PSA levels have been used in screening large populations of men for prostate cancer and have been shown to be useful.
Prior to the PSA evaluation era, nearly 70% of men diagnosed with prostate cancer already had extraprostatic or metastatic disease, and an abnormality in the prostate had to be palpably evident before a biopsy was performed.
www.emedicine.com /med/byname/prostate-specific-antigen.htm   (630 words)

 USNews.com: Health: Prostate Cancer: Prostate specific antigen (PSA) test
The PSA test was first approved by the FDA in 1986 as a way to determine whether prostate cancer had been treated successfully and to monitor for its recurrence.
However, PSA tests are now FDA approved for detection and are widely used to screen for the presence of prostate cancer.
However, it is not clear whether using the PSA test to screen for prostate cancer actually reduces the risk of death from the disease.
www.usnews.com /usnews/health/cancer/prostate/pros.test.psa.htm   (321 words)

 Prostate Specific Antigen - Cancer information on MedicineNet.com
The prostate specific antigen (PSA) is a substance produced by certain cells in the prostate gland.
Most of the PSA produced by the prostate gland is carried out of the body in semen, but a very small amount escapes into the blood stream.
The use of age-specific PSA ranges for the detection of prostate cancer is controversial.
www.medicinenet.com /prostate_specific_antigen/article.htm   (410 words)

 The Prostate-Specific Antigen (PSA) Test: Q & A - National Cancer Institute
Prostate-specific antigen (PSA) is a protein produced by the cells of the prostate gland.
It is normal for men to have low levels of PSA in their blood; however, prostate cancer or benign (not cancerous) conditions can increase PSA levels.
PSA density: PSA density considers the relationship of the PSA level to the size of the prostate.
www.cancer.gov /cancertopics/factsheet/Detection/PSA   (2145 words)

 eMedicine - Prostate-Specific Antigen : Article by Stanley A Brosman, MD
PSA is a neutral serine protease with biochemical attributes that are similar to the proteases involved in blood clotting.
PSA is found primarily in prostate epithelial cells and in the seminal fluid.
PSA screening is recommended annually for all men aged 50 years and older who have an anticipated lifespan of 10 or more years according to guidelines established by the American Urological Association and the American Cancer Society.
www.emedicine.com /med/topic3465.htm   (12085 words)

 Prostate-Specific Antigen (PSA)
PSA is released into a man's blood by his prostate gland.
PSA may increase as a result of an injury, a digital rectal exam, sexual activity (ejaculation), inflammation of the prostate gland (prostatitis), or prostate cancer.
If a PSA test is used for screening, it is usually done for men older than age 50 or for those at high risk for prostate cancer, such as men with a family history of prostate cancer, or for African-American men who have a higher chance of developing cancer than other men.
men.webmd.com /Men-Medical-Reference/Prostate-Specific-Antigen-PSA   (682 words)

 Prostate-Specific Antigen (PSA) Testing
The prostate gland is a small, chestnut-shaped gland that surrounds the male urethra (the tube from the bladder to the opening in the penis) where it emerges from the bladder.
PSA testing is also used to monitor the PSA levels of patients diagnosed with prostate cancer or benign prostatic hyperplasia.
Prostate cancer is the most commonly diagnosed cancer in men in the United State, and is the second leading cause of cancer deaths among U.S. males.
www.hmc.psu.edu /healthinfo/pq/psa.htm   (619 words)

 TEST: Prostate-Specific Antigen   (Site not responding. Last check: 2007-10-11)
Although some prostate cancers grow rapidly, many remain dormant and are found only during tests and prostate screening exams.
The prostate-specific antigen test detects levels of a protein that is produced by all kinds of prostate cells, including both normal and cancerous cells.
However, the prostate-specific antigen test may still be valuable when combined with other procedures, helping to detect the presence of prostate cancer about half the time.
tms.ecol.net /health/proanti.htm   (264 words)

 Policy on Prostate Specific Antigen Testing
While the goal of PSA testing is to detect clinically significant prostate cancers at an early stage, the report recognizes that non-significant tumors also are detected.
Prostate cancer is the most common form of non-skin cancer in United States men, and it is the second leading cause of male cancer mortality with approximately 30,000 deaths each year.
Cancer that has spread beyond the prostate to other parts of the body tends to be characterized by PSA levels that fail to fall to undetectable levels after surgery or rise despite radiation or cryotherapy; rise within 12 months of all forms of local treatment; or double in less than six months.
healthlink.mcw.edu /article/954952773.html   (566 words)

 Prostate-Specific Antigen Test Information on Healthline
Prostate-specific antigen, or PSA, is a protein produced by the prostate gland that may be found in elevated levels in the blood when a person develops certain diseases of the prostate, notably prostate cancer.
It is not specific for prostate cancer, however, as it may also be elevated in men with benign enlargement of this organ.
Although, the level of PSA usually is elevated in men with prostate cancer, it also may be abnormally high (though usually not as high) in men with non-cancerous enlargement of the prostate (benign prostatic hyperplasia or BPH).
www.healthline.com /galecontent/prostate-specific-antigen-test   (772 words)

 Prostate-Specific Antigen Nadir   (Site not responding. Last check: 2007-10-11)
The lack of an established optimum PSA nadir is a major issue in the controversy regarding irradiation of prostate cancer.
A bilateral modified pelvic Iymphadenectomy and retropubic prostate implant was performed on 346 patients and a laparoscopic pelvic lymph node dissection was performed on 18 of 190 patients who had an ultrasound-guided transperineal implant.
Patients with a pretreatment PSA level greater than 20 ng/mL have a lower disease-free survival rate, which may be related to a higher probability of undetectable metastasis at the time of treatment.
www.prostatepointers.org /prostate/fcritz/nadir.html   (4124 words)

 Prostate specific antigen - Wikipedia, the free encyclopedia
Prostate specific antigen (PSA) is a protein produced by the cells of the prostate gland.
PSA is present in small quantities in the serum of normal men, and is often elevated in the presence of prostate cancer and in other prostate disorders.
Prostate specific antigen (PSA), also known as kallikrein III, seminin, semenogelase, γ-seminoprotein and P-30 antigen) is a glycoprotein manufactured almost exclusively by the prostate gland; PSA is produced for the ejaculate where it liquifies the semen and allows sperm to swim freely.
en.wikipedia.org /wiki/Prostate_specific_antigen   (1139 words)

 Prostate Specific Antigen (PSA)   (Site not responding. Last check: 2007-10-11)
Prostate specific antigen (PSA) is a protein produced only by the prostate gland.
The prostate gland is a doughnut-shaped gland located in a man's pelvis in the small space between the base of the penis and the bladder.
If you are at increased risk for prostate cancer (for example, if you are African American or have a family history of prostate cancer), your health care provider may recommend starting screening earlier than age 50.
www.cancer.med.umich.edu /learn/prospsa.htm   (576 words)

 Prostate specific antigen
In general, the level of serum PSA reflects the mass of the prostate and the amount of tumor present, but the question to consider is whether this relationship is the same for fls as for whites.
PSA and PSM mRNA were positive in 1 and 7 of 13 EPD samples, 6 and 13 of 25 PCa samples, and 6 and 17 of 38 BPH samples.
PURPOSE: We demonstrate the effect of chronic inflammation of the prostate on the ratio of free-to-total prostate specific antigen (PSA) in serum calculated as a percentage of free PSA and, therefore, that percentage of free PSA is an unspecific means to distinguish among prostate cancer, chronic prostatitis and benign prostatic hyperplasia (BPH).
www.thedoctorsdoctor.com /labtests/prostate_specific_antigen.htm   (7749 words)

 Prostate Specific Antigen Test Kits
The amount of antibody at the internal standard is adjusted to a color intensity of the line, which is equal to the color intensity of the test line at a PSA concentration of 4 ng/mL.
These two lines are independent of the existence of PSA at the sample and indicate only the correct execution of the test.
In some cases it might be helpful to estimate the amount of PSA in the sample by comparison of the result line with the internal standard line.
www.prostatespecificantigen.net /products.htm   (329 words)

Prostate-specific antigen (PSA) test is a test that measures the level of PSA in the blood.
PSA is a substance made by the prostate that may be found in an increased amount in the blood of men who have prostate cancer.
PSA levels may also be high in men who have an infection or inflammation of the prostate or BPH (an enlarged, but noncancerous, prostate).
www.medic8.com /healthguide/articles/prostatepsa.html   (137 words)

 Prostate PSA Test - Prostate Specific Antigen Test   (Site not responding. Last check: 2007-10-11)
Though the prostate PSA test alone does not confirm the diagnosis of prostate cancer, the test does serve as a prostate tumor marker by measuring the level of a specific protein circulating in the blood.
The Prostate Specific Antigen Test is performed as a screening test for prostate cancer or to monitor progression of prostate cancer in males.
All males under treatment for prostate cancer may be recommended by their health care professional to undergo a prostate PSA test more frequently than yearly.
www.athometests.com /site/574052/page/420233   (687 words)

 ThirdAge: Prostate-specific Antigen (PSA) Test   (Site not responding. Last check: 2007-10-11)
PSA is a protein produced by the prostate, a male sex gland that generates most of the seminal fluid found in ejaculate.
PSA levels rise with age, and can also increase in response to many noncancerous conditions including benign prostate enlargement, inflammation, and infection.
If your PSA level has increased and/or the doctor notices a lump during a digital rectal exam, he or she will probably schedule diagnostic tests such as a urine test, imaging tests, x-ray, cystoscopy, or a transrectal utrasound guided needle biopsy of the prostate.
www.thirdage.com /healthgate/files/29006.html   (934 words)

 Prostate Specific Antigen (PSA) antibodies from Research Diagnostics Inc
This cocktail is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues.
PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate pithelium, and abundant in seninal fluid.
Specificity: Human prostate specific antigen (this antibody reacts with prostatic secretory and ductal epithelium in both normal and neoplastic tissue and can be useful in the identification of metastitic carninomas of prostatic origin)
www.researchd.com /miscabs/psa.htm   (776 words)

 Prostate Specific Antigen (PSA) Test Kits For Semen Detection
Our Prostate Specific Antigen (PSA) test cartridge is more sensitive than any other test cartridge based on available test data.
PSA is an accurate test which will only be positive if semen is found.
The PSA cartridge used in our kit is much more sensitive than any other PSA or P30 cartridge tested including the OneStep ABA Card® p30 based on available test data.
www.prostatespecificantigen.net   (107 words)

 Prostate Specific Antigen (PSA)
Although increased serum prostate specific antigen (PSA) can be an early indicator of prostate cancer, other conditions such as benign prostatic hypertrophy (BPH) can also cause an elevation in the serum PSA level.
The percent free PSA test measures the free-to-total PSA ration and is intended for use in conjunction with the total PSA test to aid in distinguishing between prostate cancer and benign prostate conditions.
Percent free PSA is significantly lower in individuals who have prostate cancer; therefore, this test is intended to improve the clinical usefulness of the PSA test for detecting early prostate cancer, while decreasing the number of unnecessary prostate biopsies.
www.bcbst.com /MPManual/Prostate_Specific_Antigen_PSA.htm   (622 words)

 Guidelines for Prostate Cancer Testing/Prostate Specific Antigen Testing (PSA)
PSA is a protein produced by the prostate gland.
Fifteen percent of prostate cancers are detected through this exam, but many men with abnormal digital rectal exams do not have cancer.
Men at higher risk of prostate cancer include those of African-American descent or those with a family history of developing prostate cancer before 70 years of age.
www.pamf.org /health/guidelines/psa.html   (831 words)

 Amazon.com: Prostate Specific Antigen: Books: Brawer   (Site not responding. Last check: 2007-10-11)
The discovery of prostate-specific antigen (PSA), a serine protease, was one of the most important accomplishments in urologic oncology in the past 15 years.
Today, the PSA test is an essential tool for screening, early detection, staging, definition of outcome, selection of treatment, assessment of therapeutic effects, and determination of overall prognosis.
The strengths of Prostate Specific Antigen are in its coverage of the history of PSA, the various immunoassays for PSA, PSA density and velocity, PSA levels and age, and the biochemistry of PSA.
www.amazon.com /Prostate-Specific-Antigen-Brawer/dp/0824705556   (1358 words)

 MedlinePlus Medical Encyclopedia: PSA
High PSA level has been linked to an increased chance of having, but does not mean that the person definitely has, prostate cancer.
PSA is a glycoprotein (a protein with a sugar attached) found in prostate cells.
A PSA of 4 ng/ml is abnormally high for most men and may indicate the need for further evaluation with a prostate biopsy.
www.nlm.nih.gov /medlineplus/ency/article/003346.htm   (694 words)

The prostate gland is one of the male sex glands.
It is shaped like a small dumbbell, is about the size of a walnut, and surrounds the neck of the bladder and the urethra (the tube that carries urine from the bladder through the penis).
Prostate-specific antigen (PSA) is an enzyme produced by tissue in the prostate gland.
www.sinaigrace.org /health_info/topics/canc3475.html   (191 words)

 PSA: At a Glance
To screen asymptomatic and symptomatic men for prostate cancer, to help determine the necessity for a biopsy of the prostate, to monitor the effectiveness of treatment for prostate cancer, and to detect recurrence of prostate cancer
The frequency of PSA testing is an individual decision that should be determined through discussion with your physician.
PSA testing may be performed when a man has symptoms suggestive of prostate cancer such as difficult, painful, and/or frequent urination.
www.labtestsonline.org /understanding/analytes/psa/glance.html   (178 words)

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