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Topic: Protein disulfide isomerase


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In the News (Tue 14 Feb 12)

  
  Literature Review: Evolution caught in the act?
They decided that a good candidate would be a protein called thioredoxin, because they knew it had a structure similar to one of the components of the trashed system, and has the basic chemical material needed for the job.
proteins (parts/functions) all of which or most of which are essential for the flagella to even exist and beyond that to perform its function of moving a bacterium.
The thioredoxin is then intentionally modified in four key places such that it is then identical to or at least similar to the missing native protein system that normally performs the task of creating these disulfide bonds in one of the proteins of the flagella.
www.iscid.org /boards/ubb-get_topic-f-18-t-000029.html   (3616 words)

  
 Publications
A fluorescence-based assay for the reductase activity of protein disulfide isomerase.
Menestrina G. Interaction of ostreolysin, a cytolytic protein from the edible mushroom Pleurotus ostreatus, with lipid membranes and modulation by lysophospholipids Eur J Biochem 270: 1199-1210.
In The comprehensive sourcebook of bacterial protein toxins.
tn-ibf-cnr.itc.it /pages/pubblicazioni.html   (1688 words)

  
 Cognetix   (Site not responding. Last check: 2007-09-10)
Conotoxin GI: disulfide bridges, synthesis, and preparation of iodinated derivatives.
Influence of precursor sequences and protein disulfide isomerase.
Propeptide does not act as an intramolecular chaperone but facilitates protein disulfide isomerase-assisted folding of a conotoxin precursor.
www.cognetix.com /news_publications.asp   (4884 words)

  
 Cooper
We showed that the altered region of a mutated protein in Huntington disease (HD) is a good TGase substrate in vitro.
Sam Bruschi (Washington University, Seattle) and colleagues showed that six mitochondrial proteins are targeted (thioacylated) in the rat kidney in vivo by TFEC.
Four of these proteins were identified as mitAspAT, aconitase and the Ek2 and E3 subunits of the a-ketoglutarate dehydrogenase complex (KGDHC).
www.burke.org /research/staff/cooper.htm   (2856 words)

  
 Encyclopedia of Molecular Biology, Volumes 1-4
Focusing on the fundamentals of molecular biology and encompassing all aspects of the expression of genetic information, this encyclopedia will become the first point of reference for both newcomers and established professionals in molecular biology needing to learn about any particular aspect of the field.
Aspartic Acid (Asp, D) Aspartyl Proteinase Inhibitors, Protein
Cyclic Amp Receptor Protein (CRP)/Catabolite Gene Activator Protein (CAP)
knovel.com /knovel2/Toc.jsp?SpaceID=10163&BookID=737   (147 words)

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