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Topic: Pseudomembranous colitis


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In the News (Sun 29 Nov 09)

  
  eMedicine - Pseudomembranous Colitis: Surgical Perspective : Article by Said Fadi Yassin, MD
Pseudomembranous colitis is an inflammatory disease of the colon that has changed in the last 100 years from a fatal disease caused by a postoperative event.
Pseudomembranous colitis is a surprisingly rare disease in infants and young children—a population recognized as frequent asymptomatic colonizers.
Pseudomembranous colitis usually is associated with antibiotic use, which may alter the balance of normal gut flora and allow overgrowth of certain organisms.
www.emedicine.com /med/topic2743.htm   (4326 words)

  
 Colitis - Wikipedia, the free encyclopedia
Colitis is a digestive disease characterized by inflammation of the colon.
Signs and symptoms of colitis include pain, tenderness in the abdomen, fever, swelling of the colon tissue, bleeding, erythema (redness) of the surface of the colon, rectal bleeding, and ulcerations of the colon.Tests that show these signs are plain X-rays of the colon, testing the stool for blood and pus, sigmoidoscopy, and colonoscopy.
Treatment of colitis may include the administration of antibiotics and general anti-inflammatory medications such as Mesalamine or its derivatives; steroids, or one of a number of other drugs that ameliorate inflammation.
en.wikipedia.org /wiki/Colitis   (338 words)

  
 Lifespan's A - Z Health Information Library - Pseudomembranous colitis   (Site not responding. Last check: 2007-10-09)
Pseudomembranous colitis is a complication of antibiotic therapy that causes severe inflammation in areas of the colon (large intestine).
In addition to antibiotic use, chemotherapy, advanced age, recent surgery, and history of previous pseudomembranous colitis are risk factors for this condition.
Pseudomembranous colitis is rare in infants less than 12 months old because they have protective antibodies from the mother and because the toxin does not cause disease in most infants.
www.lifespan.org /adam/healthillustratedencyclopedia/1/000259.html   (393 words)

  
 Pseudomembranous Colitis
Colonoscopy revealed pseudomembranous colitis extending from the ascending colon to the cecum, and Clostridium difficile toxin was positive in the feces.
Clostridium difficile causes pseudomembranous colitis and antibiotic-associated diarrhea.
The presence of atrophic micro-crypts, lamina propria hemorrhage, full-thickness mucosal necrosis, diffuse involvement of all the surface of all biopsies by pseudomembranes, and the endoscopic impression of a localized process, polyp, or mass were also markers of ischemia, while the endoscopic identification of diffuse pseudomembranes favored the diagnosis of C difficile.
www.thedoctorsdoctor.com /diseases/pseudomembranous_colitis.htm   (7901 words)

  
 Pseudomembranous colitis - Wikipedia, the free encyclopedia
Pseudomembranous colitis is an infection of the colon often, but not always, caused by the bacterium Clostridium difficile.
Even though they are not particularly likely to cause pseudomembranous colitis, but, rather, due to their very frequent use, cephalosporin antibiotics (such as cefazolin and cephalexin) account for a large percentage of cases.
The appearance of "pseudomembranes" on the surface of the colon or rectum is diagnostic of the condition.
en.wikipedia.org /wiki/Pseudomembranous_colitis   (1011 words)

  
 Lifespan's A - Z Health Information Library - Colitis   (Site not responding. Last check: 2007-10-09)
Colitis is an inflammation of the large intestine (colon).
Colitis may be identified by flexible sigmoidoscopy or colonoscopy  -- in both of these tests, a flexible tube is inserted in the rectum, and specific areas of the colon are evaluated.
Colitis may result in bleeding, ulceration, perforation (a hole in the colon), or toxic megacolon.
www.lifespan.org /adam/healthillustratedencyclopedia/1/001125.html   (318 words)

  
 Pseudomembranous colitis
Pseudomembranous colitis is an inflammatory condition of the colon (large intestine) that occurs in some people who have used antibiotics.
Pseudomembranous colitis occurs more often in adults than in children, and it's rare in infants because of protective antibodies they received from their mothers.
Pseudomembranous colitis is more common in certain people in hospitals and nursing homes, often when they're receiving drugs or undergoing surgery in which antibiotics are part of the treatment regimen.
edition.cnn.com /HEALTH/library/DS/00797.html   (1750 words)

  
 Clostridial Infections
Pseudomembranous colitis is caused by Clostridium difficile, bacteria that usually live harmlessly in the intestines of about 50% to 70% of newborns, 20% to 50% of infants, and 3% of adults.
Pseudomembranous colitis happens when the antibiotics used to treat childhood illnesses also kill "friendly" bacteria that normally live in the intestines.
In mild cases of pseudomembranous colitis, a child has abdominal cramps with a little watery-brown diarrhea that is not bloody.
www.kidshealth.org /parent/infections/bacterial_viral/clostridium.html   (1340 words)

  
 Pseudomembranous Colitis
Pseudomembranous colitis (PMC) is an acute colitis characterized by the formation of an adherent inflammatory membrane (pseudomembrane) overlying sites of mucosal injury.
Antibiotic- associated colitis implies a clear history of antibiotic therapy and biopsy evidence of colitis with or without formation of pseudomembrane.
Leukocytosis as a harbinger and surrogate marker of Clostridium difficile infection in hospitalized patients with diarrhea.
www.histopathology-india.net /PCo.htm   (718 words)

  
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pseudomembranous-colitis.my001.info   (146 words)

  
 Pseudomembranous Colitis: Spectrum of Imaging Findings with Clinical and Pathologic Correlation -- Kawamoto et al. 19 ...
Pseudomembranous colitis (PMC) is an acute infectious colitis
Pseudomembranous colitis: a consideration in the barium enema differential diagnosis of acute generalized ulcerative colitis.
Pseudomembranous colitis with associated fulminant ileitis in the defunc-tionalized limb of a jejunal-ileal bypass: report of a case.
radiographics.rsnajnls.org /cgi/content/full/19/4/887   (4295 words)

  
 [No title]
Pseudomembranous colitis is a form of inflammatory colitis characterized by the pathologic presence of pseudomembranes consisting of mucin, fibrin, necrotic cells, and polymorphonuclear leukocytes.
This form of colitis is pathognomonic of infection by toxin-producing Clostridium difficile and develops as a result of altered normal microflora (usually by antibiotic therapy) that favors overgrowth and colonization of the intestine by Clostridium difficile and production of its toxins.
Ulcerative colitis (UC) is a chronic, relapsing mucosal disorder that extends in continuous fashion proximally from the rectum and is limited to the colon.
www.lycos.com /info/colitis--colons.html?page=2   (679 words)

  
 Emergency Medicine
Pseudomembranous colitis was first described in 1893 when a patient with severe diarrhea was found to have "diphtheritic colitis" at autopsy.
Histologic studies show that the pseudomembrane typically arises from a point of superficial ulceration and is accompanied by an acute or chronic inflammatory infiltrate in the lamina propria.
Pseudomembranous colitis should be considered in any patient with diarrhea and recent exposure to antimicrobials.
www.emedmag.com /html/pre/gic/consults/061503.asp   (1682 words)

  
 Collagenous colitis
Biopsy specimens from the terminal ileum of 32 patients with the histopathological diagnosis of lymphocytic colitis or collagenous colitis and 11 control individuals were evaluated for the presence or absence of ileal mucosal abnormalities and for the number of intraepithelial lymphocytes, assessed by immunohistochemical stains for the pan T-cell marker, CD3.
OBJECTIVES: Collagenous colitis is a chronic diarrheal disease characterized by a normal or near-normal mucosa endoscopically and microscopic inflammation in the lamina propria, surface epithelial injury and a thick subepithelial collagen layer.
In collagenous colitis patients the life-time relative risk of colorectal cancer and the relative risk after the diagnosis of colitis with a mean observation period of 7 years was not increased.
www.thedoctorsdoctor.com /diseases/collagenous_colitis.htm   (8819 words)

  
 eMedicine - Pseudomembranous Colitis : Article by Joseph Lee, MD
This condition may also be called antibiotic-associated colitis, C difficile colitis, or C difficile diarrhea, reflecting the range of severity of this disease from mild diarrhea to life-threatening colitis.
Evaluation of PMC or antibiotic-associated colitis primarily focuses on the detection of C difficile or its toxins in stool.
The criterion standard for diagnosing PMC in patients involves the visualization of pseudomembranes on bowel mucosa or on microscopic examination of a biopsy sample, which is accomplished through a lower GI endoscopy.
www.emedicine.com /med/topic1942.htm   (3353 words)

  
 eMedicine - Clostridium Difficile Colitis : Article by Craig A Gronczewski, MD
Pathophysiology: C difficile colitis results from a disturbance of the normal bacterial flora of the colon, colonization with C difficile, and release of toxins that cause mucosal inflammation and damage.
Causes: C difficile colitis results from a disruption of the normal bacterial flora of the colon, colonization with C difficile, and release of toxins that cause mucosal inflammation and damage.
Pseudomembranes are observed in 14-25% of patients with mild disease and 87% of patients with fulminant disease.
www.emedicine.com /med/topic3412.htm   (3297 words)

  
 Emergency Medicine
Pseudomembranes develop when serum proteins, mucus, and inflammatory cells flow from the ulcer and form a membranous layer covering it.
Clostridium difficile colitis in a patient with inflammatory bowel disease may be missed because the symptoms of diarrhea, abdominal pain, and low-grade fever are attributed to a flare-up of the underlying disease process.
Severe pseudomembranous colitis, which occurs in 3% to 5% of patients with CDC, is associated with a mortality of about 65% and must be aggressively treated.
www.emedmag.com /html/pre/gic/consults/011505.asp   (3033 words)

  
 AllRefer Health - Pseudomembranous Colitis (Antibiotic Associated Colitis, Colitis - Pseudomembranous, Necrotizing ...
Pseudomembranous colitis is a complication of antibiotic therapy that causes severe inflammation (irritation and swelling with presence of excess immune cells) in areas of the colon.
Risk factors are antibiotic usage, chemotherapy for cancer, advanced age, recent surgery, and history of previous pseudomembranous colitis.
Pseudomembranous colitis is rare in infants less than 12 months old because of the presence of protective maternal antibodies.
health.allrefer.com /health/pseudomembranous-colitis-info.html   (354 words)

  
 Antibiotic-Associated Diarrhea, Pseudomembranous Colitis, and Clostridium Difficile
The incidence of pseudomembranous colitis has been diminishing in recent years, most likely due to early diagnosis of the disease and prompt antimicrobial therapy.
Thus, in recent years the terms "C difficile diarrhea" and "C difficile disease" have come to be associated with a spectrum of diseases, including pseudomembranous colitis as well as diarrhea and colitis in the absence of pseudomembranes.
Diagnosis of pseudomembranous colitis requires demonstration of pseudomembranes by colonoscopy, and C difficile can be isolated from the stools of almost all patients with this disease.
www.ncbi.nlm.nih.gov /books/bv.fcgi?rid=mmed.section.1122   (1752 words)

  
 MoonDragon's Pediatric Information - Childhood Infections: Clostridial Infections
Symptoms of pseudomembranous colitis usually begin after a child has been taking antibiotics for four to eight days, but they may start as late as five to 21 days after a child has finished taking antibiotics.
Once this is done, symptoms of mild pseudomembranous colitis often improve within two days and are usually gone within seven to ten days.
If your health care provider suspects that your child has pseudomembranous colitis, he or she will probably tell you to stop giving your child the antibiotics that caused the illness.
www.moondragon.org /obgyn/pediatric/clostridium.html   (1373 words)

  
 Postgraduate Medicine: Recurrent Clostridium difficile colitis
Pseudomembranous colitis became more prevalent in the 1970s with the proliferation of broad-spectrum antibiotics and the increased use of empirical antibiotic therapy (3).
The prevalence of complicating pseudomembranous colitis is variable but can be as great as 10% in patients taking clindamycin or lincomycin (6).
Endoscopy is not often performed for diagnosis of C difficile colitis, but it can be a useful adjunct for patients with recurrent disease and to rule out a structural comorbidity.
www.postgradmed.com /issues/2002/11_02/joyce3.htm   (2544 words)

  
 Pseudomembranous colitis
Pseudomembranous colitis is the most dramatic manifestation of C.
Methods: We report four cases of pseudomembranous colitis and review the literature.
Key words: Pseudomembranous colitis, colitis due to clostridium difficile, antibiotic- associated diarrhea.
www.imbiomed.com.mx /Gastro/Gav62n2/english/Zge72-08.html   (191 words)

  
 Clostridium difficile-Induced Colitis: Digestive Disorders: Merck Manual Home Edition
Clostridium difficile-induced colitis (also called antibiotic-associated colitis and pseudomembranous colitis) is inflammation of the large intestine that results in diarrhea.
Clostridium difficile-induced colitis should be suspected in anyone who develops diarrhea within 2 months of using an antibiotic or within 72 hours of being admitted to a hospital.
A temporary ileostomy (a surgically created connection between the small intestine and an opening in the abdominal wall that diverts stool from the large intestine and rectum) or surgical removal of the large intestine (colectomy) occasionally is needed in these severe cases as a lifesaving measure.
www.merck.com /mmhe/print/sec09/ch127/ch127a.html   (979 words)

  
 Signs of Pseudomembranous Colitis - WrongDiagnosis.com
The phrase "signs of Pseudomembranous Colitis" should, strictly speaking, refer only to those signs and symptoms of Pseudomembranous Colitis that are not readily apparent to the patient.
The word "symptoms of Pseudomembranous Colitis" is the more general meaning; see symptoms of Pseudomembranous Colitis.
This medical information about signs and symptoms for Pseudomembranous Colitis has been gathered from various sources, may not be fully accurate, and may not be the full list of Pseudomembranous Colitis signs or Pseudomembranous Colitis symptoms.
www.wrongdiagnosis.com /p/pseudomembranous_colitis/signs.htm   (343 words)

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