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| | eMedicine - Pulmonary Fibrosis, Interstitial (Nonidiopathic) : Article by Eleanor M Summerhill, MD |
 | | It is thought to begin with acute injury to the pulmonary parenchyma, leading to chronic interstitial inflammation, then fibroblast activation and proliferation, and finally progressing to the common end point of pulmonary fibrosis and tissue destruction. |
 | | Pulmonary manifestations of rheumatologic/connective-tissue disease may develop in advance of, coincident with, or many years after the onset of articular disease. |
 | | Radiation fibrosis is restricted to the previous radiation port but also may have an upper lung zone predominance, as may sarcoidosis, PLCH, HSP, pneumoconioses, and drug-related DPLD due to gold or nitrofurantoin therapy. |
| www.emedicine.com /MED/topic1961.htm (3986 words) |
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