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Topic: Pyridoxine

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	Olympus MIC-D: Polarized Light Gallery - Pyridoxine (Vitamin B-6)
		As one of the central vitamins in the B-complex, pyridoxine (better known as vitamin B-6) is a water-soluble nutrient that is vital as a precursor to a coenzyme involved in transaminations, decarboxylations, racemizations, and numerous modifications to amino acid side chains.
		Pyridoxine was discovered in the 1930s as the result of a series of nutritional investigations of rats fed vitamin-free diets.
		Commercially synthesized in a hydrochloride formulation, pyridoxine is known to organic chemists as 3,4-pyridinedimethanol, 5-hydroxy-6-methyl hydrochloride or pyridoxol hydrochloride.
	www.olympusmicro.com /micd/galleries/polarized/vitaminb6a.html (339 words)

	Vitamin B6 - pyridoxine information page. All about vitamin B6 (also known as pyridoxine) and the role it plays in your ...
		Pyridoxine is required for the balancing of hormonal changes in women as well as assisting the immune system and the growth of new cells.
		Pyridoxine might also be of benefit for children with learning difficulties, as well as assisting in the prevention of dandruff, eczema and psoriasis.
		Pyridoxine should be taken together with the entire B group vitamins, and in supplementation the quantity of B6 should be nearly the same as B2, as the B 2 is needed to activate the Pyridoxine.
	www.anyvitamins.com /vitamin-b6-pyridoxine-info.htm (731 words)

	* Pyridoxine - (Disease): Definition (Site not responding. Last check: 2007-11-06)
		Pyridoxine (B6): Deficiency in this vitamin has resulted in glucose intolerance, and it is important to include this in a hypoglycemic supplement plan.
		Pyridoxine (vitamin B6) is used to counteract nervous tissue damage.
		Vitamin B6 (pyridoxine) is one of the B group of vitamins.
	www.bestknows.com /disease/pyridoxine.html (351 words)

	Vitamin B6 ( Pyridoxine )
		Pyridoxine (Vitamin B6) is an essential coenzyme for many, if not all, of the biochemical reactions involving amino acids, the individual substances that make up protein.
		One example is the requirement for pyridoxine in the conversion of the amino acid tryptophan to niacin.
		This role may apply to heart disease, because many doctors believe that the initial defect in heart disease is in the structure of the arteries, that the integrity of the vessels is damaged and that this lays the groundwork for later deposition of fat and minerals in the vessel.
	www.herbs2000.com /vitamins/v_b6.htm (1622 words)

	Indian Pediatrics - Editorial
		Pyridoxine should be administered as a diagnostic test in all cases of convulsive disorders of infancy in which no other diagnosis is evident.
		The seizures in pyridoxine dependency are probably due to the defective synthesis of GABA resulting from an inborn abnormality of the binding of pyridoxal phosphate to GAD-65(4).
		Pyridoxine should be administered as a diagnostic test in all cases of convulsive disorders of infancy in which no other diagnosis is evident(8).
	www.indianpediatrics.net /july2003/july-633-638.htm (2221 words)

	Vitamin B6 -- Pyridoxine - Elson M. Haas M.D. - HealthWorld Online
		Pyridoxine is absorbed readily from the small intestine and used throughout the body in a multitude of functions.
		Pyridoxine may somehow be related to the development and health of the myelin covering of the nerves, which allows them to conduct impulses properly.
		Pyridoxine is a natural diuretic and is often helpful not only for the previously mentioned premenstrual problems but also in overweight and fluid-retaining people and as an adjunct to blood pressure control.
	www.healthy.net /library/books/haas/vitamins/b6.htm (2234 words)

	VITAMIN B-6 (PYRIDOXINE) (Site not responding. Last check: 2007-11-06)
		Pyridoxine supplementation should be considered in psychiatric patients with drug-induced movement disorders, such as Parkinsonism and tardive dyskinesia.
		An underlying pyridoxine deficiency in these patients may increase the risk of these drug-induced disorders, as well as worsen psychotic behavior.
		The effects of pyridoxine on movement disorders, and on psychosis, seem related to its enhancing serotonin and melatonin functions.
	www.chemicalbalance.com /vitamin_b_6.htm (1247 words)

	Healthopedia.com Drugs Information - Pyridoxine (Vitamin B 6) (Rodex, Vitabee 6, Beesix, Doxine, Nestrex, Pyri)
		Pyridoxine (peer-i-DOX-een) (vitamin B 6) is necessary for normal breakdown of proteins, carbohydrates, and fats.
		Claims that pyridoxine is effective for treatment of acne and other skin problems, alcohol intoxication, asthma, hemorrhoids, kidney stones, mental problems, migraine headaches, morning sickness, and menstrual problems, or to stimulate appetite or milk production have not been proven.
		Pyridoxine is found in various foods, including meats, bananas, lima beans, egg yolks, peanuts, and whole-grain cereals.
	www.healthopedia.com /drugs/detailed/pyridoxine-vitamin-b-6 (620 words)

	pyridoxine (vitamin B6), Eastern Carolina
		Pyridoxine is important for the breakdown of protein, fats, and carbohydrates (sugars) in the foods we eat.
		Pyridoxine is used to prevent and to treat deficiencies of pyridoxine that may be caused by an inadequate diet, medications, or genetic problems with metabolism.
		Pyridoxine is in the FDA pregnancy category A. This means that pyridoxine is considered to be safe for use during pregnancy.
	www.uhseast.com /148348.cfm (844 words)

	Vitamin B6 (Pyridoxine)
		Pyridoxine is an especially important vitamin for maintaining healthy nerve and muscle cells and it aids in the production of DNA and RNA, the body's genetic material.
		In addition to other B complex vitamins, pyridoxine is considered an "anti-stress" vitamin because it is believed to enhance the activity of the immune system and improve the body's ability to withstand stressful conditions.
		Efficacy of pyridoxine to ameliorate the cutaneous toxicity associated with doxorubicin containing pegylated (Stealth) liposomes: a randomized, double-blind clinical trial using a canine model.
	www.umm.edu /altmed/ConsSupplements/VitaminB6Pyridoxinecs.html (2754 words)

	PYRIDOXINE/vitamin B6
		Pyridoxine is a water-soluble B complex vitamin naturally present in many foods.
		Pyridoxine requirements are increased during pregnancy and breast-feeding and also in patients taking birth control or hormone replacement therapy.
		Pyridoxine should be stored in a cool (15-30C) dry place, protected from light and well out of the reach of children.
	www.tthhivclinic.com /page13473.html (537 words)

	NEL, Pyridoxine and melatonin secretion
		The melatonin onset, peak, mean and area under the curve (AUC) values after pyridoxine (3.2±1.6 pg/ml, 47.2±22.6 pg/ml, 31.5±11.0 pg/ml and 173.5 ± 138.4 pg/ml x min, respectively) were similar to the values after placebo administration (4.7± 1.6 pg/ml, 53.9± 26.0 pg/ml, 37.2± 2.8 pg/ml and 205.3± 137.8 pg/ml x min, respectively).
		The activity of pyridoxine as a coenzyme in the tryptophan metabolism was described in the kinurenine and methoxyindole pathways (5).
		The effect of pyridoxine on aromatic amino acid decarboxylase activity supports a regulatory role of pyridoxine on the synthesis of neurotransmitters (6-7).
	www.nel.edu /23_3/NEL230302A02_Luboshitzky.htm (641 words)

	Epilepsy Action: Pyridoxine Responsive Epilepsy
		Pyridoxine (also called vitamin B6, which is one of the B-complex vitamins) dependency is a very rare condition that has been recognised for about 50 years.
		The pyridoxine is then continued, either indefinitely or certainly for the next 12 months before deciding whether to undertake another ‘therapeutic challenge’ by stopping the drug.
		The dose of pyridoxine is based on the child’s weight; some children need only a small dose, while others need quite high doses, depending on how quickly the seizures stop after pyridoxine is prescribed.
	www.epilepsy.org.uk /info/pyridoxine.html (961 words)

	Product Abstract: Vitamin B6 (Pyridoxine)
		The daily doses of pyridoxine hydrochloride varied from 40 to 100 mg early in the study and from 120 to 200 mg in the later period of the investigations.
		Because the supplementation of pyridoxine (vitamin B6) improves the glucose tolerance in gestational diabetes and adult onset diabetes, pyridoxine deficiency has been considered to be one of the factors that cause diabetes mellitus.
		Pyridoxine deficiency is surely one of the factors that impair the endocrine pancreas by multifactorial derangement of metabolism besides the tryptophan-nicotinic acid pathway.
	www.lef.org /prod_hp/abstracts/php-ab417.html (7378 words)

	Product Abstract: Vitamin B6 (Pyridoxine)
		All patients were treated with vitamin B6 (pyridoxine) 100 mg/day for 14 days by mouth, after which the pyridoxine deficiency disappeared and the oral glucose tolerance improved considerably.
		Because the major neurologic complication is a peripheral neuropathy and the causes of this condition are myriad, pyridoxine may cause neuropathy only in patients with a pre-existing susceptibility to this condition.
		Their diets are deficient in pyridoxine, zinc and magnesium vs the RDA and copper and folate vs the TAD.
	www.lef.org /prod_hp/abstracts/php-ab417a.html (7261 words)

	Pyridoxine (vitamin B6) (Site not responding. Last check: 2007-11-06)
		Pyridoxine (vitamin B6)was identified as a separate component of the B-complex family in 1939.
		B6 is a family of biologically active chemical entities called pyridoxine, pyridoxamine, and pyridoxol.
		Pyridoxine has numerous functions in the body and is of primary importance in the proper action of more than 60 enzymes.
	www.suite101.com /article.cfm/589/28294 (469 words)

	eMedicine - Pyridoxine Deficiency : Article by Richard E Frye, MD, PhD
		Background: Pyridoxine 5'-phosphate is an essential cofactor in various transamination, decarboxylation, hydrolysis of glycogen, and synthesis pathways involving carbohydrate, sphingolipid, amino acid, heme, and neurotransmitter metabolism.
		Pyridoxine 5'-phosphate is an essential cofactor in various transamination, decarboxylation, and synthesis pathways involving carbohydrates, sphingolipids, sulfur-containing amino acids, heme, and neurotransmitters.
		Pyridoxine breakdown is enhanced in conditions associated with increased alkaline phosphatase levels.
	www.emedicine.com /med/topic1977.htm (1778 words)

	AANP: Pyridoxine May Reduce Carpal Tunnel Symptoms (Site not responding. Last check: 2007-11-06)
		Use of pyridoxine is not associated with any toxic effects as are the treatments commonly used for treatment of CTS symptoms, such as high doses of nonsteroidal anti-inflammatory drugs (NSAIDs).
		Pyridoxine is also easier to use than is another standard treatment for CTS -- arm splints.
		Holm cautioned that pyridoxine is contraindicated in patients with neurologic disorders who take the drug levodopa.
	www.docguide.com /dg.nsf/PrintPrint/08E39872E733583885256D5800648985 (421 words)

	Jarrow Pyridoxine/Vitamin B6 50mg, 100 cap (Site not responding. Last check: 2007-11-06)
		Pyridoxine is a water-soluble B vitamin typically found in plant products including bananas, navy beans and walnuts.
		In the body, pyridoxine is found primarily in the liver and muscles.
		Pyridoxine is utilized by the liver to synthesize pyridoxal phosphate (PLP), the active coenzyme form.
	www.nutrivance.com /product_p/jr-138.htm (117 words)

	Vitamins : Pyridoxine Hydrochloride (Vitamin B6)
		Vitamin B6, also known as pyridoxine, is an essential vitamin to aid in the formation of healthy red blood cells and supports more vital bodily functions than any other vitamin.
		Pyridoxine hydrochloride is a colorless or white crystal or a white crystalline powder.
		Vitamin B6 or pyridoxine is a coenzyme for enzymes involved in amino acid metabolism.
	www.greatvistachemicals.com /vitamins-vitamin/pyridoxine-vitamin-b6.html (652 words)

	Gale Encyclopedia of Alternative Medicine: Pyridoxine (Site not responding. Last check: 2007-11-06)
		Symptoms of pyridoxine deficiency are nonspecific, but may include nervousness, irritability, muscle twitches, insomnia, confusion, weakness, loss of coordination, and anemia.
		Since meats are the best source of pyridoxine, followed by dairy and eggs, vegans are one of the groups at risk for deficiency.
		Pyridoxine requirements are increased by the medications hydralazine, penicillamine, isoniazid, and some immunosuppressive agents.
	www.findarticles.com /p/articles/mi_g2603/is_0001/ai_2603000104 (1164 words)

	Vitamin B6 (Pyridoxine)
		Vitamin B6, or pyridoxine is one of the water soluble B-vitamins.
		By replacing the -CH OH group on position 4 of the pyridoxine molecule with -CH and -CHO respectively, two related compounds, pyridoxamine and pyridoxal can be formed which are also vitamin active.
		In the body, pyridoxine is normally stored as pyridoxal-5-phosphate (PLP), the coenzyme form of the vitamin.
	www.chm.bris.ac.uk /webprojects2002/schnepp/vitaminb6.html (106 words)

	Herb World News Online · Research Reviews
		Pyridoxine was chosen for purposes of comparison because earlier research indicates that it can be effective in alleviating various symptoms of PMS, which may include nervousness, irritability, depression, bloating, breast tenderness, weight gain, and skin and digestive problems.
		In comparison with pyridoxine, Vitex was associated with "a considerably more marked alleviation of typical PMTS complaints, such as breast tenderness, edema, inner tension, headache, constipation, and depression." Overall, 77.1% of subjects taking Vitex reported improvements, compared to 60.6% of those in the pyridoxine group.
		Side effects were reported by 5 women in the pyridoxine group and 12 in the Vitex group, including headache, gastrointestinal and lower abdominal complaints, and skin problems.
	www.herbs.org /current/vitexpms.html (349 words)

	Pyridoxine pharmacology (Site not responding. Last check: 2007-11-06)
		Discontinuation of pyridoxine results in recurrence of seizures within 1-7 days in the neonate and 2-24 days in the older infant.
		Wherever possible the initial diagnostic administration of pyridoxine should be accompanied by EEG monitoring.
		Once a definite response to treatment with pyridoxine has been established, therapy should be continued indefinitely.
	www.adhb.govt.nz /newborn/DrugProtocols/PyridoxinePharmacology.htm (207 words)

	Epidemiology of pyridoxine dependent and pyridoxine responsive seizures in the UK -- Baxter 81 (5): 431 -- Archives of ...
		This is the largest reported study of pyridoxine dependent seizures and the first national population based study.
		Because of the rarity of pyridoxine dependency, trials of pyridoxine for seizures are frequently unrewarding.
		Goutieres F, Aicardi J. Atypical presentations of pyridoxine dependent seizures: a treatable cause of intractable epilepsy in infants.
	adc.bmjjournals.com /cgi/content/full/81/5/431 (1981 words)

	* Pyridoxine - (Diet): Definition (Site not responding. Last check: 2007-11-06)
		Vitamin B6, also known as pyridoxine, helps brain function and helps the body convert protein to energy.
		Vitamin B6 or pyridoxine is an organic compound composed of hydrogen, oxygen, and nitrogen.
		However, patients taking D-penicillamine may develop a deficiency of vitamin B-6 (pyridoxine), and the physician may prescribe a supplement of 25 mg daily...
	www.bestknows.com /diet/pyridoxine.html (124 words)

	A carrier-mediated mechanism for pyridoxine uptake by human intestinal epithelial Caco-2 cells: regulation by a ...
		Confluent monolayers of Caco-2 cells were incubated in Krebs-Ringer buffer at 37°C in the presence nanomolar (A) and micromolar (B) concentrations of pyridoxine at pH 5.5 and in the presence of micromolar concentration of pyridoxine at buffer pH 7.4 (C).
		The absorption of tritium-labeled pyridoxine hydrochloride in the rat.
		Uptake of pyridoxine hydrochloride by the rat jejunal mucosa in vitro.
	ajpcell.physiology.org /cgi/content/full/285/5/C1219 (4278 words)

	Vitamin B-6
		In the IUPAC Definitive Rules for the Nomenclature of Vitamins, published in 1960 [4], the term "pyridoxine" was recommended as a generic designation of the B-6 vitamins, and "pyridoxol" as the trivial name for the alcohol form (I; R = -CH OH) previously designated as pyridoxine (Rule V-7).
		"Pyridoxine" should not be used as a generic name synonymous with "vitamin B-6" [5,6].
		The 5'-phosphoric esters of pyridoxine, pyridoxal and pyridoxamine (II; R = -CH) should be designated pyridoxine 5'-phosphate (or pyridoxine-5'-P), pyridoxal 5'-phosphate (or pyridoxal-5'-P) and pyridoxamine 5'-phosphate (or pyridoxamine-5'-P) respectively.
	www.chem.qmul.ac.uk /iupac/misc/B6.html (1357 words)

	Pyridoxine dependent epilepsy: a suggestive electroclinical pattern -- Nabbout et al. 81 (2): 125 -- Archives of ...
		Pyridoxine dependency is a rare autosomal recessive disorder causing severe neonatal epilepsy.
		Pyridoxine dependency is usually suspected in cases of recurrent and intractable neonatal seizures.
		Pyridoxine dependent seizures are a rare autosomal recessive disorder.
	fn.bmjjournals.com /cgi/content/full/81/2/F125 (2274 words)

	Pyridoxine-Dependent Seizures Registry Information
		While neonatal seizures due to pyridoxine-dependency are felt to be quite rare (6), the reports of the late-onset and other atypical presentations (2, 3, 5) along with some recent demographic data from the UK (7, 8) suggest that this is a more common clinical entity than once thought (4).
		In order to learn more about the variety of clinical presentations of pyridoxine-dependent seizures (PDS), the response of the disorder to various dosage regimens of pyridoxine, the imaging (9) and EEG (10, 11) characteristics of the disorder, and the long term developmental consequences of PDS (2, 7), we have developed a PDS Registry.
		Pyridoxine dependency: report of a case of intractable convulsions in an infant controlled by pyridoxine.
	faculty.washington.edu /sgospe/pyridoxine/Webpages/about_registry.html (474 words)

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