
	Where results make sense

Topic: Quinidine

Related Topics

ATC code C

ATC code C01

Digitoxin

Lidocaine

ATC code N

Pharmaceutical

Cardiology

Anatomical Therapeutic Chemical Classification System

Ketamine

ATC code N01

Alkaloid

Digitalis

In the News (Tue 1 Dec 09)

Northern Trust

Marvin Harrison

Peter Chernin

Gary Locke

Match Play

Penelope Cruz

Mickey Rourke

AR Rahman

Danny Boyle

Hugh Jackman

	Quinidine - AFF
		Quinidine is used to treat a variety of arrhythmias including atrial fibrillation and ventricular tachycardia.
		Quinidine is classified as a class IA antiarrhythmic drug, meaning that one of its effects is to slow the rapid inward rush of sodium ions that is involved in activating heart muscle fibers.
		Quinidine may terminate or prevent the occurrence of a number of cardiac arrhythmias including atrial fibrillation and flutter, as well as supraventricular tachycardia and ventricular arrhythmias.
	www.affacts.org /Medications/quinidine.html (861 words)

	quinidine - Heart Disease and other cardiovascular conditions on MedicineNet.com
		When quinidine is used for this indication, a second agent such as digoxin is used to slow conduction from the atria to the ventricles.
		Quinidine is avoided in patients who might be adversely affected by an agent with vagus nerve blocking effects (anticholinergic), such as those with the disease myasthenia gravis.
		Liver metabolism of quinidine is accelerated by phenobarbital, phenytoin (Dilantin), and rifampin (Rifamate), requiring an increase in quinidine dose.
	www.medicinenet.com /quinidine/article.htm (748 words)

	Quinidine (PIM 463)
		Quinidine reduces the permeability of heart muscle to electrolytes (membrane stabilizer) and is a general cardiac depressant (Brandfonbrener et al, 1966).
		Quinidine slows the rate of firing of the normal and of ectopic rhythmic foci; it raises the threshold for electrically induced arrhythmias; it protects against ventricular arrhythmias; and it prevents or terminates circus movement flutter (Goodman and Gillman, 1985).
		Quinidine concentrations are increased by antacids, cimetidine, verapamil and amiodarone; the risk of quinidine toxicity is increased by terfenadine, astemizole, and thiazide and loop diuretics.
	www.inchem.org /documents/pims/pharm/quinidin.htm (3952 words)

	Einthoven, Quinidine
		Quinidine is an antiarrhythmic agent, whose predominant electrophysiological effect is the block of the fast inward sodium channels (Class 1).
		Disposal: non metabolized quinidine (20 - 30%) and its metabolites are excreted by the kidney.
		Quinidine may "organize" atrial fibrillation in atrial flutter, possibly with a slow cycle, rarely determining 1:1 atrioventricular conduction.
	www.xagena.it /einthoven/eint0103.htm (677 words)

	MedlinePlus Drug Information: Quinidine (Systemic) (Site not responding. Last check: 2007-09-20)
		However, quinidine has been used during pregnancy and, although serious side effects are uncommon, it has been shown to cause mild uterine contractions, premature labor, and blood problems in the neonate.
		Although there is no specific information comparing use of quinidine in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults.
		However, quinidine may remain in the bodies of older adults longer than it does in younger adults, which may increase the risk of side effects and which may require lower doses.
	www.nlm.nih.gov /medlineplus/druginfo/uspdi/202498.html (1498 words)

	MedlinePlus Drug Information: Quinidine Oral
		Quinidine usually is used only to treat life-threatening arrhythmias.
		Quinidine is used to treat abnormal heart rhythms.
		Immediate-acting quinidine usually is taken three or four times a day.
	www.nlm.nih.gov /medlineplus/druginfo/medmaster/a682396.html (741 words)

	HighBeam Encyclopedia - quinidine (Site not responding. Last check: 2007-09-20)
		QUINIDINE [quinidine], heart muscle relaxant used to maintain regular heart rhythm patterns.
		Quinidine slows the rate of blood flow in heart chambers and lowers the excitability of the muscle.
		Quinidine is a general relaxant of smooth muscle and acts as a dilator of larger blood vessels.
	encyclopedia.infonautics.com /html/q/quinidin.asp (251 words)

	Quinidine, Serum
		It major uses are to maintain sinus rhythm after conversion of atrial flutter or fibrillation, to prevent ventricular tachycardia, and for long-term prophylaxis in patients with AV nodal reentrant tachycardia and automatic atrial tachycardia.
		Because it slows conduction and prolongs the refractory period of the accessory pathway and suppresses automaticity of ectopic pacemakers, quinidine may prevent recurrences of paroxysmal supraventricular tachycardia caused by reentry over a concealed pathway or AV reciprocating tachycardia associated with the Wolff-Parkinson-White syndrome.
		Quinidine is often preferred to procainamide for long-term therapy because elevated antinuclear antibody titers and drug-induced lupus are common during prolonged therapy with procainamide.
	www.labcorp.com /datasets/labcorp/html/chapter/mono/td036700.htm (410 words)

	Notice to Readers: Availability and Use of Parenteral Quinidine Gluconate for Severe or Complicated Malaria
		Pharmacists and clinicians requiring quinidine gluconate in hospitals in which an immediate source cannot be located should contact their local or regional distributor to request quinidine gluconate.
		Quinidine gluconate for malaria is administered as an initial intravenous loading dose of 10 mg/kg salt (equivalent to 6.25 mg/kg quinidine base) infused over 1--2 hours.
		Quinidine gluconate is administered subsequently as a continuous infusion of 20 µg/kg/min quinidine gluconate salt (equivalent to 12.5 µg/kg/min quinidine base) (2).
	www.cdc.gov /mmwr/preview/mmwrhtml/mm4950a5.htm (761 words)

	What You Need to Know About Quinidine
		Quinidine is used to treat irregular heartbeats (arrhythmias).
		It is important that you take quinidine regularly on the exact schedule prescribed for you, even if you have to wake up during the night to take it.
		Before quinidine is prescribed, tell your health care provider if you have heart, liver or kidney disease; asthma or another lung disease; myasthenia gravis; muscle weakness; an infection; or allergies to quinidine or quinine (a substance used to treat malaria and found in some nonprescription cold medicines).
	www.clevelandclinic.org /health/health-info/docs/0700/0728.asp?index=4921 (657 words)

	Quinidine
		Therefore, people taking quinidine should have their blood potassium and magnesium levels checked regularly and might need to supplement with both minerals, especially when taking potassium-depleting diuretics.
		Therefore, quinidine should be consistently taken with a meal to enhance drug action and to avoid potential problems.
		Sodium bicarbonate reduces the amount of quinidine eliminated from the body, which might result in increased drug side effects and toxicity.
	www.pccnaturalmarkets.com /health/Drug/Quinidine.htm (662 words)

	Rapid Induction of Histone Hyperacetylation and Cellular Differentiation in Human Breast Tumor Cell Lines following ...
		Quinidine is a natural product therapeutic agent originally used as an anti-malarial and as an anti-arrhythmic agent.
		quinidine for 0.5, 1, 2, 6, 12, 24, or 48 h; histones (20 µg/lane) were electrophoresed in 15% polyacrylamide gels containing 1% SDS and assayed for the presence of acetylated H4 by immunoblotting.
		quinidine for 15, 20, and 30 min or 9, 12, 24, or 48 h (E) or 0.5, 1, 2, or 6 h (F); extracts were electrophoresed (50 µg protein/lane) and assayed for HDAC1 protein by immunoblotting.
	www.jbc.org /cgi/content/full/275/45/35256 (5587 words)

	Modulation of quinidine-induced arrhythmias by temperature in perfused rabbit heart -- Spear and Moore 274 (3): 817 -- ...
		Quinidine was introduced directly into the perfusate from a stock solution to attain concentrations of 2 or 4 mg/l (2.5 or
		Quinidine caused a significant prolongation of the activation-recovery interval at all heart rates and temperatures.
		Quinidine preferentially blocks the slow delayed rectifier potassium channel in the resting state.
	ajpheart.physiology.org /cgi/content/full/274/3/H817 (5545 words)

	Quinidine Sulfate, side effects, drug interactions, overdose, dosage
		Quinidine is used to correct certain types of irregular heart rhythms and to slow an abnormally fast heartbeat.
		Quinidine is prescribed only for certain specific types of heart irregularity, and should be avoided when other irregularities are present.
		Quinidine is reserved for certain kinds of dangerously rapid heart irregularities.
	www.pdrhealth.com /drug_info/rxdrugprofiles/drugs/qui1368.shtml (660 words)

	quinidine drug information, quinidine side effects
		Quinidine is an antimalarial schizonticide and an antiarrhythmic agent with Class Ia activity; it is...
		Quinidine gluconate is the gluconate salt of quinidine; its chemical...
		The MULTIGENT Quinidine assay is intended for the quantitative determination of quinidine in human serum or plasma on...
	www.drugs.com /sch/quinidine (463 words)

	Ethanol Excitation of Dopaminergic Ventral Tegmental Area Neurons Is Blocked by Quinidine -- Appel et al. 306 (2): 437 ...
		Quinidine concentrations (1, 5, 10, 20, and 40 µM) were tested in 7, 8, 10, 9, and 5 neurons, respectively.
		In the presence of 40 µM quinidine, the excitatory effect of ethanol was blocked and the mean change in firing rate in response to ethanol was a small decrease (–1.7 ± 4.2%).
		In the presence of 20 µM quinidine, the magnitude of ethanol excitation was reduced to 7.8%.
	jpet.aspetjournals.org /cgi/content/full/306/2/437 (6801 words)

	Quinidine as an Antiarrhythmic -- RuDusky and Alpert 119 (5): 1617 -- Chest
		quinidine remains a drug of first choice for maintaining sinus rhythm.
		La Pointe, NM, Li, P (2000) Continuous intravenous quinidine infusion for the treatment of atrial fibrillation or flutter: a case series.
		LaPointe, NM, Li, P (2000) Continuous intravenous quinidine infusion for the treatment of atrial fibrillation or flutter: a case series.
	www.chestjournal.org /cgi/content/full/119/5/1617 (1689 words)

	Quinidine (Systemic)
		Quinidine passes into breast milk and, because of the potential for problems in the nursing infant, it is generally not recommended in mothers who are breast-feeding.
		Quinidine has not been widely studied in children; however, it is used in children to treat abnormal heart rhythms and to treat malaria.
		It is very important that your doctor check your progress at regular visits to make sure that the quinidine is working properly and does not cause unwanted effects.
	allnutritionals.com /drugs/q/quinidine-systemic.shtml (1507 words)

	Quinidine - Drugs & Vitamins - Drug Library - DrugDigest
		Quinidine can help your heart to return to and maintain a normal rhythm.
		Because your condition and the use of quinidine carry some risk, it is a good idea to carry an identification card, necklace or bracelet with details of your condition, medications and prescriber or health care professional.
		Quinidine may make your skin and eyes more sensitive to sun or ultraviolet light.
	www.drugdigest.org /DD/DVH/Uses/0,3915,582\|Quinidine,00.html (785 words)

	quinidine - [Medication]
		Quinidine may be taken with food to lessen stomach upset.
		Quinidine is in the FDA pregnancy category C. This means that it is not known whether quinidine will be harmful to an unborn baby.
		Quinidine is available with a prescription under several brand and generic names.
	www.peacehealth.org /kbase/multum/d00020a1.htm (1159 words)

	Saccharomyces cerevisiae Multidrug Transporter Qdr2p (Yil121wp): Localization and Function as a Quinidine Resistance ...
		to quinidine and barban was examined by Northern blot analysis.
		The cell suspensions used to prepare the spots in b and c were 1:2 and 1:4 dilutions of the cell suspension used in a, respectively.
		QDR2 transcription is not stimulated by the presence of quinidine or barban.
	aac.asm.org /cgi/content/full/48/7/2531 (4776 words)

	Quinidine Interactions With Human Atrial Potassium Channels : Developmental Aspects -- Nenov et al. 83 (12): 1224 -- ...
		B, Mean data showing the effect of quinidine on the current-voltage relationship for the sustained current (n=6 to 9).
		Currents before and after quinidine exposure were elicited by the voltage protocol shown in the top left corner of (C).
		Effects of quinidine on the transmembrane potentials of young and adult canine cardiac Purkinje fibers.
	circres.ahajournals.org /cgi/content/full/83/12/1224 (4261 words)

	Inhibition of P-Glycoprotein—Mediated Drug Transport : A Unifying Mechanism to Explain the Interaction Between Digoxin ...
		injection, unlabeled quinidine was dissolved in 5% glucose and
		Quinidine 5 µmol/L was applied to 1 compartment (basal or apical), and percentage of radioactivity appearing in opposite compartment at defined time points was measured.
		Inhibition of the intestinal digoxin absorption and exsorption by quinidine.
	circ.ahajournals.org /cgi/content/full/99/4/552 (4239 words)

	HighBeam Research: Library Search: Results (Site not responding. Last check: 2007-09-20)
		States in which a delay in obtaining quinidine gluconate for intravenous therapy was...
		The effects of quinine and quinidine on isolated retinal...
		appears to be correlated with the dose of quinidine, plateauing at a serum quinidine concentration...
	www.highbeam.com /library/search.asp?FN=SS&search_newspapers=on&search_magazines=on&q=quinidine&refid=ency_botnm (899 words)

	On the Mechanism by which 4-Aminopyridine Occludes Quinidine Block of the Cardiac K+ Channel, hKv1.5 -- Chen and Fedida ...
		Quinidine is an antiarrhythmic drug that blocks cardiac Na channels to alter action potential duration and slow conduction
		Superimposed are traces from the same cells after addition of different doses of quinidine until achievement of a steady state response.
		Allosteric modulation of quinidine binding by the presence of 4-AP, and vice-versa, occurs.
	www.jgp.org /cgi/content/full/111/4/539 (7238 words)

	Quinidine Drug Information
		Breast-feeding-Quinidine passes into breast milk and, because of the potential for problems in the nursing infant, it is generally not recommended in mothers who are breast-feeding.
		Amiodarone-Effects may be increased because levels of quinidine in the body may be increased
		Liver disease-Effects may be increased because of slower removal of quinidine from the body
	www.drugs.com /cons/Quinidine.html (1775 words)

	Lilly: Quinidine Gluconate Injection
		The most important ill effects of acute quinidine overdoses are ventricular arrhythmias and hypotension.
		Toxicity data for quinidine sulfate and quinidine gluconate injection (8%) solution are presented where indicated.
		Quinidine gluconate injection (8% solution) - Rat, median lethal dose 72 to 77 mg/kg, immediate circulatory collapse, reduced activity.
	ehs.lilly.com /msds/msds_quinidine_gluconate_injection.html (838 words)

	Quinidine Sulfate?
		With their doctors tend to be more satisfied with you and audio tapes and videotapes that Quinidine Sulfate?
		On alternative complementary methods of drug how should this medicine be afraid that a myth many.
		Dizzy or lightheaded and could cause dangerous problems if medicines are not stored in a refrigerator.
	pharmacy-on.builtfree.org /Quinidine-Sulfate-.html (471 words)

	Quinaglute Online, Description, Chemistry, Ingredients, Blackbox - Quinidine Gluconate - RxList Monographs
		Quinidine is an antimalarial schizonticide and an antiarrhythmic agent with Class Ia activity; it is the d-isomer of quinine, and its molecular weight is 324.43.
		Quinidine gluconate is the gluconate salt of quinidine; its chemical name is cinchonan-9-ol, 6'-methoxy-, (9S)-, mono-D-gluconate.
		Each QUINAGLUTE DURA-TABS® tablet contains 324 mg of quinidine gluconate (202 mg of quinidine base) in a matrix to provide extended-release; the inactive ingredients include confectioner's sugar, magnesium stearate, corn starch and other ingredients.
	www.rxlist.com /cgi/generic/quinidine.htm (132 words)

Try your search on: Qwika (all wikis)