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Topic: RET


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 Gene RETID76
RET expression is found in several crest-derived cell lines, spleen, thymus, lymph nodes, salivary glands, spermatogonia, and recently in normal thyroid tissue, thyroid adenoma and both papillary and follicular thyroid cell neoplasias.
RET rearrangement as RET/PTC1 is mostly detected in typical sporadic papillary thyroid carcinoma, RET/PTC3 occured at high frequency in chilhood papillary thyroid carcinoma from areas contaminated by the Chernobyl nuclear reactor accident.
Mutations of the RET proto-oncogene in Hirschsprung's disease.
www.infobiogen.fr /services/chromcancer/Genes/RETID76.html   (904 words)

  
 RET - RET proto-oncogene (multiple endocrine neoplasia MEN2A, MEN2B and medullary thyroid carcinoma 1, Hirschsprung ...
Mutation of the RET protooncogene in sporadic medullary thyroid carcinoma.
Pattern of radiation-induced RET and NTRK1 rearrangements in 191 post-chernobyl papillary thyroid carcinomas: biological, phenotypic, and clinical implications.
Distinct pattern of ret oncogene rearrangements in morphological variants of radiation-induced and sporadic thyroid papillary carcinomas in children.
www.cancerindex.org /geneweb/RET.htm   (1150 words)

  
 DuPont™ Elvaloy® RET in polymer modified asphalt (bitumen) pavement binder
The beams made with hard and soft asphalts modified with Elvaloy® RET failed at 1,000,000 and at 10,000,000 cycles, respectively, as shown in the test results.
The results indicate that Elvaloy® RET works as an antistrip agent and at the same time improves the indirect tensile strength of the mixes.
The data shows that the tensile strength of the Elvaloy® RET modified system was much higher in the dry samples.
www.dupont.com /asphalt/link4.html   (1044 words)

  
 The Sensitivity of Activated Cys Ret Mutants to Glial Cell Line-Derived Neurotrophic Factor Is Mandatory To Rescue ...
Ret was immunoprecipitated (Ip) from control and GDNF-stimulated cell lysates, and its tyrosine phosphorylation was then assessed by anti-Ptyr Western blotting.
RET activation by germ-line MEN2A and MEN2B mutations.
Arg mutation in the RET proto-oncogene associated with familial medullary thyroid carcinoma and maternally transmitted Hirschsprung's disease suggesting a role for imprinting.
mcb.asm.org /cgi/content/full/21/20/6719   (5547 words)

  
 Requirement of signalling by receptor tyrosine kinase RET for the directed migration of enteric nervous system ...
At the end of the culture period, explants were stained for RET (n,p,r) and Tuj1 (o,q,s) and counterstained with DAPI (inset in n,p).
The number of RET+ cells emigrating from small intestine towards GDNF-deficient caecum (J) or towards wild-type caecum in the presence of anti-GDNF blocking antibodies (N) is significantly reduced.
Abnormal migration of ENS progenitor cells in embryos homozygous for mutant alleles of Ret.
dev.biologists.org /cgi/content/full/129/22/5151   (7113 words)

  
 Phenotype variation in two-locus mouse models of Hirschsprung disease: Tissue-specific interaction between Ret and ...
the genes encoding the RET receptor tyrosine kinase and the endothelin
Singly, the null alleles of Ret and Ednrb are strictly recessive for the enteric phenotype.
) mice (A) and a piebald homozygous (Ret
www.pnas.org /cgi/content/full/100/4/1826   (4769 words)

  
 Highly Recurrent RET Mutations and Novel Mutations in Genes of the Receptor Tyrosine Kinase and Endothelin Receptor B ...
Highly Recurrent RET Mutations and Novel Mutations in Genes of the Receptor Tyrosine Kinase and Endothelin Receptor B Pathways in Chinese Patients with Sporadic Hirschsprung Disease -- Garcia-Barceló et al.
of the receptor tyrosine kinase (RET) and endothelin receptor
Germline mutations of the RET ligand GDNF are not sufficient to cause Hirschsprung disease.
www.clinchem.org /cgi/content/full/50/1/93   (4339 words)

  
 Instruction Set RET   (Site not responding. Last check: 2007-10-21)
The address is usually placed on the stack by a CALL instruction, and the return is made to the instruction that follows the CALL.
The optional numeric parameter to RET gives the number of stack bytes (OperandMode=16) or words (OperandMode=32) to be released after the return address is popped.
If these registers refer to segments that cannot be used by the new privilege level, they are set to 0 to prevent unauthorized access from the new privilege level.
www.online.ee /~andre/i80386/Opcodes/RET.html   (251 words)

  
 Familial Medullary Thyroid Carcinoma with Noncysteine RET Mutations: Phenotype-Genotype Relationship in a Large Series ...
The protooncogene RET comprises 21 exons and encodes a receptor tyrosine
Distribution of the protooncogene RET mutations in the 148 patients belonging to the 47 kindreds with the FMTC phenotype studied
In conclusion, FMTC kindreds with RET mutations in exon 13,
jcem.endojournals.org /cgi/content/full/86/8/3746   (5905 words)

  
 The RET Receptor Is Linked to Stress Response Pathways -- Myers and Mulligan 64 (13): 4453 -- Cancer Research
Real-time PCR quantitation of gene expression in response to RET.
Mograbi B, Bocciardi R, Bourget I, et al The sensitivity of activated Cys Ret mutants to glial cell line-derived neurotrophic factor is mandatory to rescue neuroectodermic cells from apoptosis.
The high transforming potency of erbB-2 and ret is associated with phosphorylation of paxillin and a 23 kDa protein.
cancerres.aacrjournals.org /cgi/content/full/64/13/4453   (7356 words)

  
 Multiple endocrine neoplasia type 2 and RET: from neoplasia to neurogenesis -- Hansford and Mulligan 37 (11): 817 -- ...   (Site not responding. Last check: 2007-10-21)
RET's functions in normal and tumorigenic cells are mediated by a complex series of downstream interactions.
Heterogeneous mutation of the RET proto-oncogene in subpopulations of medullary thyroid carcinoma.
RET alternative splicing influences the interaction of activated RET with the SH2 and PTB domains of Shc, and the SH2 domain of Grb2.
www.jmedgenet.com /cgi/content/full/37/11/817   (6910 words)

  
 Research Experience for Teachers (RET)
The RET is part of our long-range strategy for reaching out to multiple sectors of the educational community.
RET participants will be active members of our faculty's research groups, conducting research in one of four areas: Microstructured Polymers, Crystalline Organic Semiconductors, Magnetic Heterostructures, the Nanoparticle-Based Materials Proto-IRG, or one of the various Seed groups.
Each RET participant will work in a team under the direction of a specific principal investigator (PI), with post doctoral/graduate students from the PI’s group and, where appropriate, with a REU student.
www.mrsec.umn.edu /ehr/retdescription.shtml   (444 words)

  
 Reverse Engineering Team
A few stood out from the crowd, but always in time they took their place among the rest, except with their sites being mirrored and their knowledge they brought to the people stored for a time.
When we came together as a group, RET was nothing more than an idea, but over the last while, we have become stronger and stronger as a group and are well on our way to producing a great amount of very useful tools and information.
Our goal is to always move one step further than the rest of the knowledge out there so that we might increase our understanding and the understanding of people around us.
www.reteam.org   (237 words)

  
 Various Mechanisms Cause RET-mediated Signaling Defects in Hirschsprung's Disease -- Pelet et al. 101 (6): 1415 -- ...
and expression of the ret proto-oncogene encoding a tyrosine kinase
of the ret proto-oncogene with MEN2A or MEN2B mutation.
mutations of the RET ligand, GDNF, are not sufficient to cause
www.jci.org /cgi/content/full/101/6/1415   (5026 words)

  
 Functional haplotypes of the RET proto-oncogene promoter are associated with Hirschsprung disease (HSCR) -- Fitze et ...   (Site not responding. Last check: 2007-10-21)
RET polymorphisms are over- or under-represented in HSCR populations.
Eng, C. (1996) The RET proto-oncogene in multiple endocrine neoplasia type 2 and Hirschsprung's disease.
Patrone, G., Puliti, A., Bocciardi, R., Ravazzolo, R. and Romeo, G. (1997) Sequence and characterisation of the RET proto-oncogene 5' flanking region: analysis of retinoic acid responsiveness at the transcriptional level.
hmg.oxfordjournals.org /cgi/content/full/12/24/3207   (4828 words)

  
 Assessment of RET/PTC Oncogene Activation and Clonality in Thyroid Nodules with Incomplete Morphological Evidence of ...
RET activation was analyzed in 46 thyroid nodules by immunohistochemistry with RET(TK) antibodies.
RET Activation and Clonality in Thyroid Nodules with Minimal or Incomplete Evidence of Papillary Carcinoma
Santoro M, Carlomagno F, Romano A, Bottaro DP, Dathan NA, Grieco M, Fusco A, Vecchio G, Matoskova B, Kraus MH, Di Fiore PP: Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B.
ajp.amjpathol.org /cgi/content/full/160/6/2157   (5848 words)

  
 Familial Medullary Thyroid Carcinoma with Noncysteine RET Mutations: Phenotype-Genotype Relationship in a Large Series ...
Familial Medullary Thyroid Carcinoma with Noncysteine RET Mutations: Phenotype-Genotype Relationship in a Large Series of Patients -- Niccoli-Sire et al.
in the protooncogene RET, mainly in exons 10, whereas noncysteine
Screening of six risk exons of the RET proto-oncogene in families with medullary thyroid carcinoma in the Czech Republic
jcem.endojournals.org /cgi/content/abstract/86/8/3746   (675 words)

  
 Oncological implications of RET gene mutations in Hirschsprung's disease -- Sijmons et al. 43 (4): 542 -- Gut
Oncological implications of RET gene mutations in Hirschsprung's disease
Germline mutations of the RET proto-oncogene identical to those found in the tumour predisposition syndrome multiple
Sixty patients with Hirschsprung's disease were screened for RET mutations.
gut.bmjjournals.com /cgi/content/abstract/43/4/542   (374 words)

  
 retnetwork.org -2003 RET Conference
Examine impacts in the classroom instruction and professional practices of RET Participants.
Look at benefits to mentor scientists including improved awareness of K-12 science criteria, necessity of teacher resources, and mentoring and supervisory strategies.
Address the value of the RET program for departments, research centers, and institutions.
www.retnetwork.org   (59 words)

  
 Polymorphisms G691S/S904S of RET as Genetic Modifiers of MEN 2A -- Robledo et al. 63 (8): 1814 -- Cancer Research
RET have a modifier effect on the age at onset of MEN 2A.
The RET proto-oncogene encodes a tyrosine kinase receptor
Borrego S., Saez M. E., Ruiz A., Gimm O., Lopez-Alonso M., Antinolo G., Eng C. Specific polymorphisms in the RET proto-oncogene are over-represented in patients with Hirschsprung disease and may represent loci modifying phenotypic expression.
cancerres.aacrjournals.org /cgi/content/full/63/8/1814   (3360 words)

  
 The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in ...
The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells -- Schuetz et al.
The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells
Ret, which binds specifically to a PDZ-binding motif present
www.jcb.org /cgi/content/abstract/167/5/945   (267 words)

  
 Molecular Modeling of the Extracellular Domain of the RET Receptor Tyrosine Kinase Reveals Multiple Cadherin-like ...
RET sequence delineated four distinct N-terminal domains, each
We have also investigated the role of Ca in ligand binding by RET and found that Ca ions are required for RET binding to GDNF but not for GDNF binding
Phenotype-genotype correlation in Hirschsprung disease is illuminated by comparative analysis of the RET protein sequence
www.jbc.org /cgi/content/abstract/276/38/35808   (588 words)

  
 Various Mechanisms Cause RET-mediated Signaling Defects in Hirschsprung's Disease -- Pelet et al. 101 (6): 1415 -- ...
RET locus in HSCR is associated with various molecular mechanisms
Intrinsic susceptibility to misfolding of a hot-spot for Hirschsprung disease mutations in the ectodomain of RET
The RET proto-oncogene induces apoptosis: a novel mechanism for Hirschsprung disease
www.jci.org /cgi/content/abstract/101/6/1415   (1070 words)

  
 Badger Meter, Inc., Recordall Electronic Transmitters   (Site not responding. Last check: 2007-10-21)
The RET provides a scaled pulse output and optional 4-20 mA analog output signal.
The RET is environmentally sealed, making it ideally suited for submersible applications.
Badger's Line of ER registers are battery operated remote indicators designed for use with Badger's RET transmitters.
www.badgermeter.com /unisy.htm   (297 words)

  
 RET at Northeastern University
The Research Experiences for Teachers (RET) program at Northeastern University and University of Massachusetts-Lowell is a six-week summer research experience funded by the National Science Foundation for middle and high school mathematics and science teachers and Community College STEM faculty.
Participants work in research laboratories affiliated with the Colleges of Arts and Sciences and Engineering, the Center for Subsurface Sensing and Imaging Systems (CenSSIS) at Northeastern University, and the Centers for High-rate Nanomanufacturing at Northeastern University and the University of Massachusetts-Lowell.
Northeastern University does not discriminate on the basis of race, color, religion, religious creed, sex, sexual orientation, age, national origin, ancestry, veteran or disability status.
www.ret.neu.edu /overview.html   (186 words)

  
 Specific haplotypes of the RET proto-oncogene are over-represented in patients with sporadic papillary thyroid ...
Specific haplotypes of the RET proto-oncogene are over-represented in patients with sporadic papillary thyroid carcinoma -- Lesueur et al.
Specific haplotypes of the RET proto-oncogene are over-represented in patients with sporadic papillary thyroid carcinoma
of the RET proto-oncogene are present in up to 66% of sporadic
jmg.bmjjournals.com /cgi/content/abstract/39/4/260   (443 words)

  
 TTF-1 and RET promoter SNPs: regulation of RET transcription in Hirschsprung's disease -- Garcia-Barcelo et al. 14 (2): ...   (Site not responding. Last check: 2007-10-21)
TTF-1 and RET promoter SNPs: regulation of RET transcription in Hirschsprung's disease -- Garcia-Barcelo et al.
RET coding region haplotypes, their implication in the transcriptional
RET promoter SNPs in LD with the main coding region RET haplotype
hmg.oupjournals.org /cgi/content/abstract/14/2/191   (336 words)

  
 Multiple endocrine neoplasia type 2 and RET: from neoplasia to neurogenesis -- Hansford and Mulligan 37 (11): 817 -- ...
the RET receptor tyrosine kinase are found in the vast majority
Role of MEN2A-Derived RET in Maintenance and Proliferation of Medullary Thyroid Carcinoma
Familial medullary thyroid carcinoma and prominent corneal nerves associated with the germline V804M and V778I mutations on the same allele of RET
www.jmedgenet.com /cgi/content/abstract/37/11/817   (1048 words)

  
 RET Percussion Drums   (Site not responding. Last check: 2007-10-21)
RET Percussion's mission is to bring you "The Best of Both Worlds" by combining acoustic and electronic drum products.
Utilizing real drum heads for a true feel, RET Percussion has released its latest debut in its custom shop electronic drum line.
The NS2™ line from Rhythm Electronic Technology Percussion is the next generation of design in the Natural series kits.
shop.drumbalaya.com /s.nl/sc.2/category.344/.f   (300 words)

  
 Signal Transduction Pathways Activated by RET Oncoproteins in PC12 Pheochromocytoma Cells -- Xing et al. 273 (9): 4909 ...
Signal Transduction Pathways Activated by RET Oncoproteins in PC12 Pheochromocytoma Cells -- Xing et al.
Gene alterations in the ret proto-oncogene, which encodes a receptor tyrosine kinase, have been found to associate with several
In contrast, a RET mutant found in a patient
www.jbc.org /cgi/content/abstract/273/9/4909   (605 words)

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