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Topic: RNA gene


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RNA
DNA

In the News (Fri 27 Nov 09)

  
  Roles of PSF protein and VL30 RNA in reversible gene regulation.
This mechanism of reversible gene regulation appears to be involved in normal functions such as steroidogenesis and in pathological functions such as oncogenesis (5).
Tumor suppressor genes are frequently mutated in tumor cells, inactivating or deleting the encoded tumor suppressor protein (6).
Another mutation of the PSF gene, which is frequently detected in human papillary renal cell carcinomas, involves a translocation that fuses part of the PSF gene with the TFE3 gene, inactivating the normal function of the PSF protein (8, 9).
www.euchromatin.com /Song01.htm   (4438 words)

  
  Non-coding RNA - Wikipedia, the free encyclopedia
Ribosomal RNA (rRNA) is the primary constituent of ribosomes.
Small nucleolar RNA (snoRNA) is a class of small RNA molecules that are involved in chemical modifications of ribosomal RNAs (rRNAs) and other RNA genes, for example by methylation.
Efference RNA (eRNA) is derived from intron sequences of genes or from non-coding DNA.
en.wikipedia.org /wiki/RNA_gene   (1136 words)

  
 RNA in Gene De-Repression.
If these stimulated RNA species are found to be absent from non-stimulated cells, then the process of lymphocyte activation can be viewed as involving gene de-repression, and that is already suggested by the character of ultrastructural changes observed during lymphocyte activation [15].
Certain species of nuclear RNA appear capable of recognizing specific base sequences on the DNA template during such gene de-repression [3], and thus are strong candidates as the molecular species which effects locus-specific and strand-specific gene de-repression in animals [19].
De-repressor RNA (dRNA) is thought to bind to the anti-coding strand of the DNA templateduring gene de-repression [19], and therefore to be complementary in base sequence to operator RNA [29].
www.euchromatin.net /Rna00.htm   (2328 words)

  
 Non-Coding RNA Genes and the Modern RNA World.
Various cis-antisense RNAs have been observed in prokaryotes [50], plants [51] and animals [12], and their roles are unlikely to be limited to those in imprinting and chromatin structure.
RNA genes are immune to frameshift or nonsense mutations, and are often small and multicopy, which makes them difficult (even impossible) targets for recessive mutational screens.
Self-splicing RNA: autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena.
www.euchromatin.org /Eddy01.htm   (9521 words)

  
 RNA GENiE - RNA Gene Prediction
This program locates novel RNA genes based on the premise that all stable, functional RNAs share common structural elements and that sequences corresponding to these elements would occur preferentially in RNA genes.
Also UNCG tetraloops, tetraloop receptors and adenosine platforms are expected to occur in higher frequency in RNA genes and thus to be useful for their identification.
Since neural networks based on the occurrence of RNA structural elements can not be expected to identify non-RNA sequences in a positive manner, we used additional sequence based neural networks based on global sequence descriptors (previously applied to protein fold prediction) to discriminate RNA genes from non-RNA genes.
rnagene.lbl.gov   (269 words)

  
 RNA gene   (Site not responding. Last check: 2007-09-23)
An RNA gene is any gene that encodes RNA that functions without being translated into a protein.
Commonly-used synonyms of "RNA gene" are noncoding RNA or non-coding RNA (ncRNA) and small RNA (sRNA).
The most prominent examples of RNA genes are transfer RNA (tRNA) and ribosomal RNA (rRNA), both of which are involved in the process of translation.
usapedia.com /r/rna-gene.html   (815 words)

  
 RNA glossary
Because alternative RNA splicing allows different types of mRNA molecules to be created from a single gene, it generates the diversity of protein function and structure that is essential to complex organisms.
RNA molecules which hybridize to complementary sequences in either RNA or DNA altering the function of the latter.
Structural genomics of RNA will be most interesting when integrated with experimental and computational methods for identifying novel RNA genes and determining their biological relevance: an approach defined previously as 'ribonomics' [11].
www.genomicglossaries.com /content/RNA.asp   (5337 words)

  
 IBC Life Sciences
This mechanism, RNA interference, is activated when RNA molecules occur as double-stranded pairs in the cell.
It is of great importance for the regulation of gene expression, participates in defense against viral infections, and keeps jumping genes under control.
RNA interference is already being widely used in basic science as a method to study the function of genes and it may lead to novel therapies in the future.
www.ibclifesciences.com /news/first.xml   (319 words)

  
 Transcription
An enzyme, an RNA polymerase, binds to the complex of transcription factors.
In eukaryotes, this requires — at least for protein-encoding genes — that the nucleosomes in front of the advancing RNA polymerase (RNAP II) be removed.
DNA transcription of the genes for mRNA, rRNA, and tRNA produces large precursor molecules ("primary transcripts") that must be processed within the nucleus to produce the functional molecules for export to the cytosol.
users.rcn.com /jkimball.ma.ultranet/BiologyPages/T/Transcription.html   (2201 words)

  
 The RNAi Web: RNAi/RNAi Books
Gene Silencing by RNA Interference: Technology and Application provides background in the field and describes methods and protocols for gene silencing.
This book is a comprehensive guide to gene silencing by RNA interference methods for beginners and experienced professionals in the field.
The ability of double stranded RNA to inhibit the expression of genes with an appropriate sequence can be harnessed to silence target genes in vitro in a new and powerful way.
www.rnaiweb.com /RNAi/RNAi_Books   (543 words)

  
 OriGene - RNA - shRNA Gene Silencing Sets
Gene silencing through the use of shRNA has become a primary tool for characterizing gene involvement in disease states and interactive pathways.
In stable transfection, introduction of a plasmid expressing short hairpin RNA (shRNA) with a selection marker allows selection for cells that have continuous suppression of the gene through expression of the short hairpin construct.
HuSH-29 is considered the RNA interference method of choice because it can be easily adapted to the conditions, either transient or stable, required for any individual experiment.
www.origene.com /rna   (972 words)

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