| | News - Aldosterone Antagonists Prevent RAAS Escape and May Help Prevent Target Organ Damage |
 | | Aldosterone receptor antagonists can inhibit renin-angiotensin-aldosterone system (RAAS) escape mechanisms that can occur during therapeutic RAAS blockade and may be useful in preventing target-organ injury, according to a review article on the subject. |
 | | Aberrations in the RAAS have been implicated in congestive heart failure, elevated arterial blood pressure, kidney disease, and other disease states, while agents that target the RAAS, such as angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) have been shown to be protective in multiple ways. |
 | | Aldosterone receptor antagonists appear to antagonize the effects of RAAS escape in experimental animal models. |
| www.docguide.com /news/content.nsf/news/8525697700573E1885256D96003112F5 (585 words) |