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Topic: Radioiodine

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	Austin Radiological Association - Radiology Services & Exams - Radioiodine Treatment (Site not responding. Last check: 2007-11-04)
		Radioiodine, also known as I-131, is a form of iodine that is accumulated by the thyroid gland identically to regular iodine.
		Radioiodine treatment is a common, well accepted form of treatment that has been used all over the world for more than 40 years.
		The radioiodine dose that is given for other thyroid treatment is not considered strong enough to affect the salivary glands, so this step is not necessary unless you are being treated for thyroid cancer.
	www.ausrad.com /rse_le_nm_radioiodine.shtml (1485 words)

	Radioiodine definition - Medical Dictionary definitions of popular medical terms
		Radioiodine: An isotope of the chemical element iodine that is radioactive.
		Radioiodine is used in diagnostic tests as well as in radiotherapy of an hyperactive thyroid gland (hyperthyroidism), most often due to Graves disease.
		Radioiodine is the preferred initial therapy for the hyperthyroidism of Graves disease in North America while antithyroid drugs are used as the first line of treatment in most of the rest of the world.
	www.medterms.com /script/main/art.asp?articlekey=5187 (214 words)

	Radioiodine Ablation and Treatment for Papillary and Follicular Thyroid Cancer
		Radioiodine ablation is radiation therapy in which radioactive iodine is administered to destroy or ablate residual healthy thyroid tissue remaining after thyroidectomy.
		Radioiodine treatment is radiation therapy in which radioactive iodine is administered to destroy or ablate thyroid cancer by irradiating that tissue.
		Other physicians use “ablation” to mean the administration of radioiodine to eliminate any normal thyroid tissue remaining in the neck after initial surgery and “treatment” to mean the subsequent administration of radioiodine for the elimination of metastatic disease in the neck or elsewhere.
	www.thyca.org /ablation.htm (731 words)

	The Effect of Methimazole on Thyroid Uptake of Pertechnetate and Radioiodine in Normal Cats
		Administration of methimazole prior to radioiodine treatment is recommended by some clinicians so that cats have relief from the hyperthyroid state for several weeks in order to evaluate renal function and make the cats more stable medically for isolation during treatment.
		Radioiodine treatment is not reversible, as is methimazole dosage, and effective treatment of hyperthyroidism in a cat with concurrent renal failure may result in decreased glomerular filtration and uncompensated renal failure.
		Since altered radioiodine uptake was not present 15 and 24 days after stopping methimazole treatment, recommendations to discontinue this antithyroid medication for to weeks before radioiodine treatment seem reasonable.
	www.vspn.org /Library/Journals/VSPN_AbstractOWeek031403.htm (899 words)

	Newswise
		Typically, radioiodine treatment for cancer of the thyroid gland requires temporary discontinuation of thyroid hormone replacement for several weeks, leading to weight gain, constipation, fatigue, slowed thinking, depressed mood, muscle cramps, intolerance of cold temperatures and other symptoms.
		Paradoxically, for radioiodine treatment to be effective, thyroid hormone treatments previously had to be suspended, according to Ladenson.
		As they were prepared for radioiodine treatment, the group denied thyroid hormone therapy had significantly higher total symptom scores at weeks two and four.
	www.newswise.com /articles/view/517188 (667 words)

	AllThyroid.org: Ask the Doctor - Risks of Radioiodine
		The exposure to the gonads (ovaries or testicles) from a typical dose of radioiodine used to treat hypothyroidism is very similar to that from a number of other common radiologic procedures, for example, a barium enema, intravenous pyelography (kidney x-ray), or pelvic CT scan.
		Since all the dormant eggs are exposed to the radioiodine at the time of treatment, there is no logical basis for a recommendation regarding the interval during which a woman should avoid conception.
		In controlled clinical studies, the incidence of birth defects in babies born to mothers who have taken radioiodine was identical to the incidence found in mothers who had not taken radioiodine.
	www.tsh.org /askthedoctor/radioiodinerisks.html (486 words)

	AMCCC.com \| Veterinary Specialists of South Florida
		Radioiodine therapy has some distinct advantages over the other methods of treatment but it also has at least one drawback.
		The advantages are that it eliminated the need for lifetime medication, there is no chance that the patient will develop a problem with the antithyroid medication, it eliminates the need for anesthesia and the risk of hypocalcemia (low blood calcium.) The major drawback is that it requires a brief period of isolation from the family.
		The bulk of the remainder is excreted primarily in the urine and to a lesser degree the feces.
	www.amccc.com /report.html (2810 words)

	Radioiodine I-131 therapy
		Radioactive Iodine I-131 (also called Radioiodine I-131) therapy is a treatment for an overactive thyroid, a condition called hyperthyroidism.
		Radioiodine should never be used in a patient who is pregnant or nursing.
		The radioiodine I-131 is swallowed in a single dose, in capsule or liquid form, and is quickly absorbed into the bloodstream in the gastrointestinal (GI) tract and concentrated from the blood by the thyroid gland, where it begins destroying the gland's cells.
	radiologyinfo.org /en/info.cfm?pg=radioiodine (1034 words)

	Radioiodine Information Sheet
		In a recent study of 524 hyperthyroid cats treated with radioiodine1, the overall response to treatment was considered good in 94% of the cats.
		Radioiodine treatment has been used in human medicine for over 50 years and is recognized as a safe and effective method of treating human patients with hyperthyroidism.
		The dose of radioiodine used to treat hyperthyroid cats is very small and people and other animals are at very low risk from the radiation.
	vmthpub.vetmed.wisc.edu /sa_services/med/int_med/radioiodine.htm (735 words)

	Calibrating Germanium Detectors for Assaying Radioiodine in Charcoal Cartridges Daniel Montgomery Analytics (Site not responding. Last check: 2007-11-04)
		Since radioiodine may be present in various chemical forms including elemental iodine, organic iodide species and other inorganic species, the charcoal cartridges are impregnated with KI or TEDA (tetraethylenediamine) to convert organic iodide species to forms that are collected on charcoal.
		The fraction of particulate radioiodine is variable and dependent on the source of radioiodine and other conditions such as pre‑release treatment of the effluent stream (e.g.
		The thickness of the radioiodine distribution corresponded to 0-mm, 3-mm, 5-mm, I0-mm, 15-mm, and 25-mm (homogeneous).
	www.analyticsinc.com /paper3.htm (2509 words)

	[No title]
		Treatment with radioiodine avoids the inconvenience of daily oral administration and the side effects associated with antithyroid drugs, as well as the risks and postoperative complications associated with anesthesia and surgical thyroidectomy.2,3 Ideally, administration of a single dose of radioiodine would restore euthyroidism without inducing hypothyroidism.
		In 1986, we initiated a protocol for subcutaneous radioiodine treatment of cats with hyperthyroidism in which the dose was determined on the basis of severity of the cat's clinical signs, thyroid tumor size, and magnitude of the serum T4 concentration.
		Estimation of radioiodine dose--On the day cats were admitted to the hospital for radioiodine treatment, a complete physical examination (including careful digital palpation of the thyroid gland) was performed, and serum T4 concentration was determined.
	www.vet.purdue.edu /vcs/scottmon/ptrsonar.doc (1695 words)

	Radioiodine Plus Prednisone for Grave's Disease is Less Likely to Worsen Ophthalmopathy and More Likely to Cause ...
		Patients treated with radioiodine for Grave's disease are more likely to have worsening of eye findings when compared with those patients who treated with radioiodine plus prednisone or methimazole.
		Patients are more likely to have regression of their eye findings if treated with radioiodine plus prednisone compared with those who treated with radioiodine alone or methimazole.
		The radioiodine groups (with and without steroids), the patients with preexisting ophthalmopathy were more likely to have worsening of their disease, compared with those patients with no previous eye findings.
	www.med.umich.edu /pediatrics/ebm/cats/graves.htm (574 words)

	PATIENT INFORMATION FOR PATIENTS UNDERGOING RADIOIODINE THERAPY
		Radioiodine treatment uses a form of iodine that is radioactive.
		Radioiodine can occasionally cause slight neck and face discomfort and a temporary increase in thyroid activity which goes away within 2 weeks and usually within a few days.
		NO, 40 years of experience of using radioiodine shows no effect on the health of the children of patients who have had radioiodine.
	www.beaumont.ie /depts/lab/endocrinology/Radio-Iodine.htm (3738 words)

	Johns Hopkins Gazette \| January 17, 2006
		Paradoxically, for radioiodine treatment to be effective, thyroid hormone treatments previously had to be suspended, Ladenson said.
		Before radioiodine treatment, Billewicz scores revealed the groups to be comparable, with mild and transient symptoms reported by only eight patients in each group.
		Eight months after radioiodine therapy, tests showed that remaining thyroid cells had been successfully destroyed in all patients in both groups, the study reported.
	www.jhu.edu /~gazette/2006/17jan06/17thyroi.html (624 words)

	I131 AUDIT of radioiodine treatment of thyrotoxicosis (Site not responding. Last check: 2007-11-04)
		The amount of radioiodine given should be sufficient to achieve euthyroidism in most patients within 2 to 3 months with a moderate rate of hypothyroidism thereafter i.e.: 15-20% at two years.
		If radioiodine is used in patients with ophthalmopathy, prophylactic steroids should be considered and hypothyroidism avoided.
		All patients who received radioiodine treatment in the year 1997-98 were identified by liasing with Northampton general hospital.
	www.guthormones.co.uk /audit.htm (1174 words)

	UpToDate Radioiodine treatment of differentiated thyroid cancer
		Like iodine, radioiodine is taken up and concentrated in thyroid follicular cells because they have a membrane sodium-iodide transporter [1].
		Compared with normal thyroid follicular cells, thyroid cancer cells have reduced expression of the transporter, which may account for the low 131-I uptake in thyroid cancer tissue [1].
		Radioiodine therapy for differentiated thyroid cancer is reviewed here.
	patients.uptodate.com /topic.asp?file=thyroid/10531 (580 words)

	Comparison of radioiodine and antithyroid drugs in the treatment of thyrotoxicosis (Site not responding. Last check: 2007-11-04)
		The purpose of the present study is to compare the two choices of treatment, the radioiodine and antithyroid drug therapy.
		Patients unresponsive to at least six months of drug therapy or patients with disease recurrence after, at least, a three month remission period, were treated with 8-15 mci, of radioiodine and continuation of antithyroid therapy until reaching a euthyroid state.
		Conclusion: On a short term basis, the outcome of thyrotoxicosis for remission is similar either by radioiodine or antithyroid drug therapy, but development of hypothyroidism in the former and persistance of hyperthyroid state in the latter, gives radioiodine therapy priority.
	www.ijem.org /iranian/13/5.html (410 words)

	Iodine-131 - Wikipedia, the free encyclopedia
		Iodine-131, also called radioiodine, is a radioisotope of iodine.
		Patients receiving radioiodine treatment are warned not to have sexual intercourse for seven days, not to hug or hold children, a one or two metre distance may be recommended, and women are told not to become pregnant for six months afterwards.
		For security reasons, there is no information available in the public domain on which airports use radiation detectors.
	en.wikipedia.org /wiki/Radioiodine (413 words)

	Radioiodine Facilities
		Some methods of radioiodine dose determination rely on the physical palpation of the thyroid gland alone to estimate tumor size.
		Some facilities that perform radioiodine therapy rely on patient care and monitoring provided by veterinary technicians who report to off site veterinarians regarding the condition of the hospitalized patients.
		At Advanced Veterinary Medical Imaging all patients receiving radioiodine therapy are evaluated, treated and then supervised for the duration of their hospital stay by Dr. Michael Broome.
	www.avmi.net /NewFiles/Hyperthyroidism/RadioiodineFacilities.html (1043 words)

	Disposition of Radioiodine 131I Therapy for Thyroid Carcinoma in a Patient with Severely Impaired Renal Function on ...
		Disposition of Radioiodine 131I Therapy for Thyroid Carcinoma in a Patient with Severely Impaired Renal Function on Chronic Dialysis: a Case Report -- Magné et al.
		Radioiodine treatment of thyroid carcinoma in patients on maintenance hemodialysis.
		Management of thyroid papillary carcinoma with radioiodine in a patient with end stage renal disease on hemodialysis.
	jjco.oxfordjournals.org /cgi/content/full/32/6/202 (1411 words)

	Salivary and Lacrimal Gland Dysfunction (Sicca Syndrome) After Radioiodine Therapy -- Solans et al. 42 (5): 738 -- The ...
		of radioiodine therapy on the salivary and lacrimal glands.
		Salivary gland scintigraphy stages depend on salivary gland uptake and excretion: stage 1, normal uptake and excretion; stage 2, mild to moderate dysfunction; stage 3, moderate to severe dysfunction; and stage 4, severe dysfunction.
		Radioiodine was orally administered in a single dose according
	jnm.snmjournals.org /cgi/content/full/42/5/738 (3547 words)

	Radioiodine and thyroid eye disease -- Walsh et al. 319 (7202): 68 -- BMJ
		The mechanism by which radioiodine exacerbates ophthalmopathy is poorly understood, as is the pathogenesis of thyroid eye
		Radioiodine may be used in patients with mild eye disease but
		Lazarus JH, on behalf of the Radioiodine Audit Subcommittee of the Royal College of Physicians Committee on diabetes and Endocrinology, and the Research Unit of the Royal College of Physicians.
	bmj.bmjjournals.com /cgi/content/full/319/7202/68 (852 words)

	Unusual uptake of radioiodine in the chest in a patient with thyroid carcinoma -- Nair et al. 77 (913): 63 -- The ...
		Unusual uptake of radioiodine in the chest in a patient with thyroid carcinoma -- Nair et al.
		Unusual uptake of radioiodine in the chest in a patient with thyroid carcinoma
		Radioiodine uptake in rheumatoid arthritis associated lung disease mimicking thyroid cancer metastases.
	bjr.birjournals.org /cgi/content/full/77/913/63 (1705 words)

	Long Term Effects of Radioiodine Ablation
		Developed in the 1950’s, the iodine radioisotope I-131, the form of radioiodine most often used, is generally created as a byproduct of nuclear waste or by nuclear fission.
		The effects of radioiodine on thyroid cells include both cell destruction and cell mutations.
		Generally regarded as safe, recent studies of survivors of radioiodine fallout and long-term studies of treated hyperthyroid patients question long-term safety.
	www.suite101.com /article.cfm/graves_disease/60453 (490 words)

	Radioiodine Treatment of Hyperthyroidism--Prognostic Factors for Outcome -- Allahabadia et al. 86 (8): 3611 -- Journal ...
		Radioiodine Treatment of Hyperthyroidism--Prognostic Factors for Outcome -- Allahabadia et al.
		The use of radioiodine in hyperthyroidism is increasing, particularly
		Radioiodine ablation of the thyroid to prevent recurrence of amiodarone-induced thyrotoxicosis in patients with resistant tachyarrhythmias
	jcem.endojournals.org /cgi/content/full/86/8/3611 (4663 words)

	Antithyroid Drugs and Radioiodine Therapy: A Grain of (Iodized) Salt -- Cooper 121 (8): 612 -- Annals of Internal ...
		radioiodine in variable-fraction patients who were not pretreated
		Discontinuation of antithyroid therapy before ablation with radioiodine in Graves' disease.
		A reappraisal of the role of methimazole and other factors on the efficacy and outcome of radioiodine therapy of Graves' hyperthyroidism.
	www.annals.org /cgi/content/full/121/8/612 (1543 words)

	Prophylactic Use of Potassium Iodide (KI) in Radiological Emergencies*: Information for Physicians
		The radiation dose to the thyroid that results from the uptake of radioiodine increases the risk of thyroid cancer, especially among children.
		Potassium iodide when taken before, or shortly after exposure to radioiodine, is effective in reducing radioiodine uptake by the thyroid gland.
		FDA indicates that across populations at risk for radioiodine exposure, the overall benefits of KI far exceed the risks of overdosing, especially in children, although it continues to emphasize particular attention to dose in infants.
	www.health.state.ny.us /environmental/radiological/potassium/ki_md.htm (1198 words)

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