| | A brief history of schizophrenia |
 | | Schizophrenia is extremely uncommon before adolescence and puberty, suggesting that the surge of altered steroid hormone biosynthesis associated with this stage of development, and possibly also those steroid hormones which are elevated in response to stress during these critical career-forming years of life, may also be implicated in the etiology of schizophrenia. |
 | | Interest in an inherited causality for schizophrenia came from observations that schizophrenia often appeared to be clustered in families, an identical (monozygous) twin having a 40 to 50% chance of developing the illness, and a child of a schizophrenic parent around 10%. |
 | | Schizophrenia is a disabling condition with an age of onset which is earlier for men (15-25) than for women (25-35), with a lifetime prevalence of 1.3% within the U.S. population (NIMH, or 2-3 million Americans, of whom fewer than 1 in 5 recover fully. |
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