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Topic: Reserpine

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	MedlinePlus Drug Information: Reserpine, Hydralazine, and Hydrochlorothiazide
		Reserpine, hydralazine, and hydrochlorothiazide is no longer available in the U.S. If you are currently taking reserpine, hydralazine, and hydrochlorothiazide, you should call your doctor to discuss switching to another treatment.
		The combination of reserpine, hydralazine, and hydrochlorothiazide is used to treat high blood pressure.
		Reserpine and hydralazine work by relaxing the blood vessels so that blood can flow more easily through the body.
	www.nlm.nih.gov /medlineplus/druginfo/medmaster/a601108.html (740 words)

	Reserpine - Wikipedia, the free encyclopedia
		Reserpine depletion of monoamine neurotransmitters in the synapses is often used to bolster the theory that depletion of the neurotransmitters causes subsequent depression in humans.
		Reserpine was isolated in 1952 from the dried root of Rauwolfia serpentina (Indian snakeroot),
		Reserpine may be used as a sedative for horses.
	en.wikipedia.org /wiki/Reserpine (528 words)

	Reserpine- an alkaloid derived from Rauwolfia Vomitoria Root Bark. (Site not responding. Last check: 2007-10-13)
		Reserpine is a naturally occurring drug that has been used for centuries in ancient India.
		The purified alkaloid, reserpine, was isolated in 1952 and is considered the first modern drug for the treatment of hypertension.
		Reserpine irreversibly binds to the storage vesicles of neurotransmitters, particularly norepinephrine, serotonin and dopamine.
	www.indo-world.com /reserpine/reserpine.htm (232 words)

	Reserpine (PIM 467)
		The potential for reserpine toxicity should be considered in cases where there is no specific history of ingestion but there is potential access to reserpine, the presence of hypertension treated with unknown medications, or the use of unidentified herbal medications.
		Reserpine inhibits normal sympathetic activity by decreasing the storage of catecholamines at the pre-synaptic, CNS, and peripheral neuron.
		Reserpine assays are not generally performed, and it is unlikely that they would be of benefit in the management of reserpine toxicity.
	www.inchem.org /documents/pims/pharm/reserpn.htm (3785 words)

	Reserpine India, rauwolfia serpentina India, rauwolfia serpentina hypertension, reserpine for horses, reserpine ... (Site not responding. Last check: 2007-10-13)
		Reserpine was the first drug found to interfere with the human sympathetic nervous system, and it initiated the effective pharmacotherapeutic control of hypertension.
		Reserpine impairs the storage of biogenic amines by interfering with an uptake mechanism.
		Reserpine is principally advocated in case of mild to moderate hypertension, insomnia and in psychiatric disorder but with extreme precaution.
	www.sssbiotic.com /product/reserpine.asp (392 words)

	The biological fate of reserpine -- Stitzel 28 (3): 179 -- Pharmacological Reviews
		Orally administered reserpine is readily absorbed from the GI tract.
		metabolism in the biotransformation of reserpine in vivo are not known.
		rapid redistribution of the reversibly bound reserpine from the tissues.
	pharmrev.aspetjournals.org /cgi/content/abstract/28/3/179 (473 words)

	MedlinePlus Drug Information: Reserpine
		Reserpine is used to treat high blood pressure.
		Reserpine controls high blood pressure or symptoms of agitation, but does not cure them.
		Abruptly stopping reserpine may increase blood pressure and cause unwanted side effects.
	www.nlm.nih.gov /medlineplus/druginfo/medmaster/a601107.html (723 words)

	reserpine (Site not responding. Last check: 2007-10-13)
		By reducing sympathetic activity to blood vessels, reserpine relaxes capacitance vessels and reduces total peripheral resistance.
		Reserpine enters the brain, and depletion of cerebral amine stores causes sedation, nightmares, mental depression, and parkinsonism symptoms.
		Reserpine disappears rapidly from the circulation, but its effects persist much longer owing to the irreversible inactivation of catecholamine storage granules.
	lysine.pharm.utah.edu /netpharm/netpharm_00/druglist/reserpine.htm (175 words)

	Carilion - Reserpine, Hydralazine, and Hydrochlorothiazide(Systemic) - [Medication] (Site not responding. Last check: 2007-10-13)
		Reserpine, hydralazine, and hydrochlorothiazide re-SER-peen, hye-DRAL-a-zeen, and hye-droe-KLOR-oh-THYE-a-zide combinations are used to treat high blood pressure (hypertension).
		Pregnancy—Too much use of reserpine and hydrochlorothiazide during pregnancy may cause unwanted effects (jaundice, blood problems, low potassium, difficult breathing, low temperatures, and loss of appetite) in the baby.
		Although there is no specific information comparing use of reserpine, hydralazine, and hydrochlorothiazide combination in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults.
	www.carilion.com /kbase/htm/mdx-/drde/2025/06/mdx-drde202506.htm (2704 words)

	Reserpine For Veterinary Use
		Reserpine is used as a long acting tranquilizer in horses.
		Reserpine was once used in pregnant mares in an attempt to treat "fescue toxicosis." Domperidone has largely replaced reserpine for this use.
		• Reserpine is a prohibited substance in most sanctioned competition and is a frequent cause of drug violations due to the long and variable withdrawal period.
	www.wedgewoodpharmacy.com /monographs/reserpine.asp (704 words)

	BioMed Central \| Abstract \| Reserpine methonitrate, a novel quaternary analogue of reserpine augments urinary excretion ...
		Reserpine, an alkaloid from Rauwolfia serpentina was widely used for its antihypertensive action in the past.
		In the present investigation, reserpine methonitrate (RMN), a novel quaternary analogue of reserpine was synthesised and evaluated biochemically for its central and peripheral amine depleting actions in rats while its influence on the blood pressure was measured in anaesthetized rats in comparison with reserpine
		Reserpine treatment (5 mg/kg) produced a significant increase in the urinary excretion of VMA, 5-HIAA and HVA while RMN at doses of equal to and double the equimolar doses of reserpine (5 and 10 mg/kg) produced significant increase in VMA and 5-HIAA excretion without producing any effect on HVA excretion compared to control animals.
	www.biomedcentral.com /1471-2210/4/30/abstract (368 words)

	Medical Dictionary: Reserpine - WrongDiagnosis.com
		Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
		Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals.
		Reserpine : alkaloid isolated from the root of Rauwolfia species, used as an antihypertensive and sedative.
	www.wrongdiagnosis.com /medical/reserpine.htm (301 words)

	Uni Serp Drug Information
		Reserpine lowers blood pressure by decreasing the levels of certain chemicals in your blood.
		Hydralazine/ hydrochlorothiazide/ reserpine is in the FDA pregnancy category C. This means that it is not known whether hydralazine/ hydrochlorothiazide/ reserpine will harm an unborn baby.
		Hydralazine/ hydrochlorothiazide/ reserpine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants.
	www.drugs.com /mtm/U/Uni_Serp.html (1634 words)

	The Stork Synthesis of (-)-Reserpine
		The history of reserpine (3), isolated from the Indian shrub Rauwolfia serpentina, is storied.
		The anxiolytic activity of reserpine, the first tranquilizer, pointed the way to the development by Hoffmann-LaRoche of the blockbuster drugs Librium and Valium.
		Condensation of 2 with 6-methoxytryptamine (1) led to reserpine (3).
	www.organic-chemistry.org /Highlights/2006/01May.shtm (373 words)

	Reserpine, Hydralazine, and Hydrochlorothiazide (Systemic) - MayoClinic.com
		Too much use of reserpine and hydrochlorothiazide during pregnancy may cause unwanted effects (jaundice, blood problems, low potassium, difficult breathing, low temperatures, and loss of appetite) in the baby.
		Reserpine passes into breast milk and may cause unwanted effects (difficult breathing, low temperature, loss of appetite) in infants of mothers taking large doses of it.
		The dose of reserpine, hydralazine, and hydrochlorothiazide combination will be different for different patients.
	www.mayoclinic.com /health/drug-information/DR202506 (2742 words)

	RESERPINE TABLETS
		Reserpine acts centrally to produce characteristic sedation and tranquillisation; it also produces a generalised increase in parasympathetic activity and a depression of responses to peripheral adrenergic nerve activity.
		Reserpine is recommended for the treatment of hypertension, mild anxiety states and chronic psychoses.
		In severe hypertension or long established cases of hypertension, reserpine may be used together with more potent hypertensives (allowing them to be used in smaller doses) and in which case, the reserpine enhances the reaction to bring about the desired relief within a short time.
	home.intekom.com /pharm/lennon/reserpin.html (365 words)

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