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Topic: Resveratrol


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In the News (Sun 20 Dec 09)

  
 Resveratrol : by Ray Sahelian, M.D., Resveratrol Benefits, Anti-Aging potential
Resveratrol is a potent chemical and studies show it has anti-inflammatory, antioxidant, anti-infective properties, and it activates the longevity gene in fruit flies and worms.
Resveratrol 's anti-influenza activity seems to center on its ability to interfere with key "host-cell functions" that are essential for virus replication, the authors explain in The Journal of Infectious Diseases, May 15, 2005.
After resveratrol treatment, the apoptosis rate of the neuroblastoma cells significantly increased, a significant accumulation of cells occurred at the S phase of the cell cycle, p21 was downregulated, and cyclin E was upregulated.
www.raysahelian.com /resveratrol.html   (4066 words)

  
 Resveratrol
Melissa Q.B. McElderry, M.S., R.D. Resveratrol (trans-3,5,4'-trihydroxystilbene), a compound found largely in the skins of red grapes, is a component of Ko-jo-kon, an oriental medicine used to treat diseases of the blood vessels, heart [1,2], and liver [2].
Resveratrol is a phytoalexin, a class of antibiotic compounds produced as a part of a plant's defense system against disease [1].
Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor.
www.quackwatch.org /01QuackeryRelatedTopics/DSH/resveratrol.html   (1183 words)

  
 Resveratrol: Cutting-Edge Technology Available Today
Resveratrol is the first natural medicinal to have solid evidence behind it showing that it blocks or stops many stages of cancer.
Resveratrol is a broad-spectrum agent that stops cancer in many diverse ways, from blocking estrogen and androgens to modulating genes.
Resveratrol inhibits human breast cancer cell growth and may mitigate the effect of linoleic acid, a potent breast cancer cell stimulator.
www.lef.org /resveratrol   (3021 words)

  
 Resveratrol - Herbal Index - herbindex.net
Resveratrol was first isolated from an extract of the Peruvian legume Cassia quinquangulata in 1974.
Resveratrol is available as a mass-produced nutritional supplement but not as a therapeutic agent (though it is now registered as an investigational drug).
Resveratrol has been shown to induce Fas/ Fas ligand mediated apoptosis, p53 and cyclins A, B1 and cyclin-dependent kinases cdk 1 and 2, furthermore it possesses antioxidant and anti-angiogenic properties.
www.herbindex.net /resveratrol.html   (1062 words)

  
 Resveratrol
Resveratrol is one of a group of compounds (called phytoalexins) that are produced in plants during times of environmental stress, such as adverse weather or insect, animal, or pathogenic attack.
Resveratrol has been identified in more than 70 species of plants, including mulberries and peanuts, and the skins of red grapes, which are a particularly rich source (Jang et al.
Application of 1, 5, 10 or 25 [micromoles] of resveratrol together with TPA twice a week for 18 weeks reduced the number of skin tumors per mouse by 68, 81, 76 or 98% respectively, and the percentage of mice with tumors was lowered by 50, 63, 63 or 88%, respectively.
www.alternativehealth.co.nz /cancer/vitamins/resveratol.htm   (4757 words)

  
 Resveratrol
Resveratrol is a naturally occurring phytoalexin produced by some higher plants in response to injury or fungal infection.
Resveratrol is the parent molecule of a family of polymers called viniferins.
In a rat study of the effect of resveratrol on ischemia-reperfusion, it was found that the substance had a dramatic effect against ischemia-reperfusion-induced arrhythmias and mortality.
www.pdrhealth.com /drug_info/nmdrugprofiles/nutsupdrugs/res_0224.shtml   (2355 words)

  
 Resveratrol - Wikipedia, the free encyclopedia
Resveratrol is produced by plants as an antifungal chemical.
Resveratrol has recently been reported to be effective against neuronal cell dysfunction and cell death, and may be of use for diseases such as Huntington's disease
Inhibition of cardiac fibroblast proliferation and myofibroblast differentiation by resveratrol.
en.wikipedia.org /wiki/Resveratrol   (1465 words)

  
 Resveratrol
Resveratrol is a phytoalexin, a class of antibiotic compounds.
Resveratrol now exists as a mass-produced nutritional supplement but not as a beneficial agent (though it is now registered as an investigational drug).
It has been clinically researched that resveratrol appears to be the first molecule to consistently cause life extension across very different animal groups such as worms, insects, and fish, and it could become the starting molecule for the design of drugs for the prevention of human aging-related diseases.
www.getnutri.com /Resveratrol.html   (663 words)

  
 Grape Seed Extract resveratrol antioxidant grape skin
The authors reviewed studies examining resveratrol's ability to suppress proliferation of a wide variety of tumor cells, including lymphoid and myeloid cancers; cancers of the breast, colon, pancreas, stomach, prostate, head and neck, ovary, liver, lung and cervical cancers; melanoma; and muscles.
Besides inhibiting proliferation, resveratrol was also shown to induce apoptosis through one of two pathways (inducing Fas-dependent apoptosis in some cell lines, and Fas-independent apoptosis in others) in b-cell and t-cell lymphomas; myeloid leukemia; breast, colon, pancreas, stomach, prostate, thyroid and head and neck, ovary, liver, lung, and cervical cancers; and melanoma.
Discovering the mechanisms of resveratrol is important to developing the compound as a cancer-preventive agent for humans, said John Pezzuto, a University of Illinois at Chicago researcher who first reported resveratrol's link to red wine and fighting cancer in 1997.
www.allvita.net /resverat.htm   (978 words)

  
 resveratrol index page
Resveratrol, a natural compound from nature, appears to be the first molecule to consistently cause life extension across very different animal groups such as worms, insects and fish, and could become the starting molecule for drugs for the prevention of human aging-related diseases.
Trans resveratrol, considered the more biologically active molecule, is the form of resveratrol known to activate the Sirtuin 1 DNA-repair gene.
Longevinex introduced its synergistic combination red wine extract dietary supplement (trans resveratrol, quercetin, rice bran, lecithin) in 2004 (patent applied for), which is designed to synergistically preserve and prolong the biological action of trans resveratrol in a dietary supplement.
www.resveratrolnews.com   (772 words)

  
 Page title - should be under 70 characters
In both model systems, resveratrol suppressed the deleterious effects of mutant huntingtin, as assessed by loss of the twitch response in the worms and cell death of the mouse neurons.
Resveratrol is commonly referred to as a 'dirty' molecule in the pharmaceutical industry, meaning that it seems to interact with many different proteins, including COX1/2, ribonucleotide reductase and SIRT1.
Similarly, in mouse neurons, the action of resveratrol is blocked by the Sir2 inhibitors sirtinol and nicotinamide.
www.resveratrolnews.com /page23.htm   (1194 words)

  
 RESVERATROL
Resveratrol, found in grapes and wine, reduces the harmful effects of cholesterol and halts many stages of cancer
Resveratrol is one of the most versatile and effective plant compounds there is It represents a novel solution to many common problems encountered by aging humans.
Resveratrol (chemical formula 3,5,4’-trihydroxy-trans-stilbene) is only found in any quantity in the skin of young unripe red grapes, (as well as the skins of peanuts and a herb known as Knotweed).
www.antiaging-systems.com /a2z/resveratrol.htm   (490 words)

  
 RESVERATROL 50 mg - health-marketplace.com
Resveratrol supplements significantly reversed the trend.[4] In this respect, resveratrol is similar to Viagra, which also affects nitric oxide.
Finally, resveratrol also stops the proliferation of cells in blood vessels that narrow the arteries,[5] and it also keeps blood cells from sticking together.[6] Both are very important for preventing heart attacks.
Researchers in Austria have done elaborate studies showing that resveratrol blocks the ability of cancer cells to metastasize to bone (30-71%).[24] The highest results were for pancreas, breast, and renal cancer.
www.health-marketplace.com /Resveratrol-50.htm   (3025 words)

  
 Dimerization of Resveratrol by the Grapevine Pathogen Botrytis cinerea
Resveratrol (trans-3,4',5-trihydroxystilbene) is produced by grapes (Vitis spp.) in response to microbial attack by the fungal grapevine pathogen Botrytis cinerea.
Resveratrol is then transformed by the plant into several more potent antifungal agents.
In addition, we are interested in using microorganisms both as in vitro models to mimic and predict the metabolic fate of resveratrol in mammalian systems and as biocatalysts to prepare new resveratrol analogues that may possess significant biological activity.
pubs.acs.org /cgi-bin/jtextd?jnprdf/63/i01/html/np990266n   (4290 words)

  
 Resveratrol definition - Medical Dictionary definitions of popular medical terms
Resveratrol is a type of polyphenol called a phytoalexin, a class of compounds produced as part of a plant's defense system against disease.
It is produced in the plant in response to an invading fungus, stress, injury, infection, or ultraviolet irradiation.
Resveratrol has been shown to reduce tumor incidence in animals by affecting one or more stages of cancer development.
www.medterms.com /script/main/art.asp?articlekey=25930   (225 words)

  
 Resvert™, 25mg Resveratrol & 100 mg Proanthrocyanadins per capsule, qnt: 60 capsules.   (Site not responding. Last check: 2007-11-03)
Resveratrol is a compound produced by many plant species and is thought to be helpful in reducing serum lipids and may have favorable cardiovascular implications.
Resveratrol is studied by nutritionists and biochemists because of its potential as an anticancer and cardioprotective compound.
Resveratrol's antioxidant properties may again be the mechanism at work in reducing the oxidation of LDL cholesterol.
www.youngagain.com /resvert.html   (1110 words)

  
 Resveratrol-phytonutrient in grapes -WINE
Published research on resveratrol -- a phytonutrient found in fresh grapes -- has nearly tripled in the past two years, indicating strong interest in the health benefits of this compound.
Resveratrol, found mainly in the skins of grapes, is noted for its antioxidant and anti-inflammatory properties and its potential to prevent cancer and heart disease.
Researchers at the University of Missouri-Kansas found that resveratrol and quercetin alone inhibited oral cancer cell growth, but when cells were treated with a combination of resveratrol and quercetin, the inhibitory effect on cell growth was enhanced.
www.annieappleseedproject.org /resingrap.html   (745 words)

  
 Inhibition of gastric cancer cell proliferation by resveratrol: role of nitric oxide -- Holian et al. 282 (5): 809 -- ...
Resveratrol is a dietary phytochemical that has been shown to inhibit proliferation of a number of cell lines, and it behaves
Inhibition of DNA synthesis by resveratrol was statistically significant in the absence and presence of all H
Suppression of nitric oxide synthase and the down-regulation of the activation of NF B in macrophages by resveratrol.
ajpgi.physiology.org /cgi/content/full/282/5/G809   (4971 words)

  
 ScienceDaily: Red Wine's Health Benefits May Be Due In Part To "Estrogen" In Grape Skin   (Site not responding. Last check: 2007-11-03)
The substance, resveratrol, is highly concentrated in the skin of grapes and is abundant in red wine.
Resveratrol has a molecular structure similar to that of diethylstilbestrol, a synthetic estrogen.
The researchers also found that resveratrol could replace estradiol in supporting the proliferation of certain breast cancer cells that require estrogen for growth.
www.sciencedaily.com /releases/1997/12/971219062019.htm   (1951 words)

  
 Resveratrol Revelations
Resveratrol is most abundant in vine fruits, especially red grapes; pine trees; peanuts; and most abundantly in polygonum cuspidatum, an Asian plant used for centuries for heart and liver ailments.
This is why it is thought that the water- and fat-soluble vitamins, such as C and E, appear to help prevent heart disease, as they each protect against certain free radicals that oxidize the bad "fats/proteins" in the blood.
Because resveratrol is highest in polygonum cuspidatum, combining this single phytonutrient in pharmaceutical grade with red wine, whole grape polyphenols (RWP), as naturally found in nature, is likely the best supplemental approach.
www.chiroweb.com /archives/22/09/15.html   (1529 words)

  
 USNews.com: Red wine: a toast to lower cholesterol
A spate of recent studies point to a possible reason: France's equally strong taste for red wines that contain resveratrol, a chemical compound proven to extend the lives of yeast cultures and fruit flies, and which may have similarly beneficial effects on humans by lowering cholesterol levels.
Resveratrol, which Sinclair thinks should be renamed "reversatrol" for its life-sustaining properties, is produced naturally by grapes to fight off fungal diseases that can take hold when it's damp outside.
For example, since resveratrol is found primarily on grape skins, it is almost nonexistent in most white wines, which are fermented only after the skins are removed.
www.usnews.com /usnews/culture/articles/030929/29wine.div.htm   (563 words)

  
 Pure Encapsulations   (Site not responding. Last check: 2007-11-03)
* Resveratrol is a compound often associated with the health benefits of red wine, because of its powerful antioxidant and cardioprotectant properties.
Pure Encapsulations Resveratrol is derived from one of the richest known sources, Polygonum cuspidatum, an herb utilized for centuries.
Resveratrol is standardized to contain 20% trans resveratrol and 10% emodin, providing enhanced cardiovascular and antioxidant support.
www.purecaps.com /itemdy00.asp?T1=RE1   (134 words)

  
 Resveratrol enhances the expression of non-steroidal anti-inflammatory drug-activated gene (NAG-1) by increasing the ...
Resveratrol enhances the expression of non-steroidal anti-inflammatory drug-activated gene (NAG-1) by increasing the expression of p53 -- Baek et al.
Resveratrol enhances the expression of non-steroidal anti-inflammatory drug-activated gene (NAG-1) by increasing the expression of p53
Resveratrol induces apoptosis in a p53-dependent manner (11)
carcin.oxfordjournals.org /cgi/content/full/23/3/425   (5342 words)

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