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Topic: Reticulocyte


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In the News (Fri 14 Jun 19)

  
  Reticulocyte Count | Caremark Health Resources
Reticulocytes were first described as transitional forms of red blood cells by Wilhelm H. Erb in 1865.
A low reticulocyte count indicates that the bone marrow is not producing a normal number of red blood cells.
A dye that is used to stain the blood cells for the reticulocyte count.
healthresources.caremark.com /topic/topic100587405   (654 words)

  
  Reticulocyte count
A reticulocyte count is usually performed when patients are evaluated for anemia and response to its treatment.
Reticulocytes were first described as transitional forms of red blood cells by Wilhelm H. Erb in 1865.
A low reticulocyte count indicates that the bone marrow is not producing a normal number of red blood cells.
www.lifesteps.com /gm/Atoz/ency/reticulocyte_count_pr.jsp   (778 words)

  
 Reticulocyte - Wikipedia, the free encyclopedia
Reticulocytes are also slightly larger, which can be picked up as a high MCV (mean corpuscular volume) with a full blood count done by machine.
The reticulocyte count is the percentage of circulating red blood cells that are in the reticulocyte stage.
Reticulocytes increase in number and percentage when there is increased production of red blood cells such as in a haemolytic anaemia or sickle cell anemia.
en.wikipedia.org /wiki/Reticulocyte   (351 words)

  
 INTEGRATED CASE: HEMATOLOGY #1
Reticulocytes are defined as immature red cells seen in the peripheral blood that contain at least two dots of reticulin material reactive with new methylene blue (NMB) in their cytoplasm.
Reticulocytes are counted as the number of NMB-reactive cells per 1,000 red cells and expressed as percent reticulocytes (absolute number per 100 red cells).
Interobserver variation and uneven distribution of reticulocytes on the new methylene blue smear introduces a high analytic variation in reticulocyte counting; interlaboratory coefficients of variation in the 20% range are common, a degree of imprecision of which every clinician should be aware.
www.meddean.luc.edu /lumen/MEdEd/mech/cases/case7/answer1.htm   (1479 words)

  
 Medicare News Update, Issue 99-#8
Reticulocytes are immature, anucleated RBCs containing remnants of ribonucleic acid (RNA), which appear as a dark blue network (reticulum) after incubation in new methylene blue or brilliant cresyl blue.
The reticulocyte count is therefore usually corrected for the anemia by multiplying the measured percentage (reticulocyte count) by the ratio of the patient's hematocrit against a normal hematocrit to obtain the reticulocyte index.
The reticulocyte count is commonly indicated in the evaluation of unexplained anemia and may be useful in the evaluation of response to therapeutic intervention.
www.urmc.rochester.edu /path/Medicare/reticulo.htm   (920 words)

  
 Reticulocyte Count: The Test
The reticulocyte count is ordered to help determine if the bone marrow is responding adequately to the body’s need for RBCs and to help determine the cause of and classify different types of anemia.
The number of reticulocytes must be compared to the number of RBCs to calculate a percentage of reticulocytes; thus, the test is ordered along with a RBC count.
A reticulocyte count may be ordered when a patient has a decreased RBC count and/or a decreased hemoglobin and hematocrit and the doctor wants to evaluate bone marrow function.
www.labtestsonline.org /understanding/analytes/reticulocyte/test.html   (919 words)

  
 Reticulocyte Count - Health CentersNews Story - WTAE Pittsburgh
This is a test that measures the percentage of reticulocytes (slightly immature red blood cells) in blood.
The number of reticulocytes in the blood indicates how quickly they are being produced and released by the bone marrow.
The reticulocyte count may be increased during pregnancy.
www.thepittsburghchannel.com /encyclopedia/6864700/detail.html   (772 words)

  
 Reticulocyte Count - Good Health by SETON
The reticulocyte count rises when there is a lot of blood loss or in certain diseases in which red blood cells are destroyed prematurely, such as hemolytic anemia.
The reticulocyte count is given as the percentage of red blood cells that are reticulocytes (the number of reticulocytes divided by the total number of red blood cells, multiplied by 100).
A reticulocyte count may help a doctor decide other tests that need to be done to diagnose a specific type of anemia or other disease.
www.goodhealth.com /health_a_to_z/health_library/medical_test/reticulocyte_count   (879 words)

  
 Revista Brasileira de Hematologia e Hemoterapia - Reticulocyte parameters in hemoglobinopathies and iron deficiency ...   (Site not responding. Last check: 2007-10-16)
New reticulocyte parameters have been used in the diagnosis and management of anemias, in the bone marrow transplant setting and in the monitoring of iron replacement or erythropoiet in therapy.
The reticulocyte count is clinically important for evaluating the erythropoietic activity of bone marrow and for diagnosis of anemia.
Reticulocyte maturity as an indicator for estimating qualitative abnormality of erythropoesis.
www.scielo.br /scielo.php?script=sci_arttext&pid=S1516-84842003000200005   (2426 words)

  
 Diagnostic Edge - January 2004
Reticulocytes are nonnucleated red blood cell precursors that typically do most of their maturation within the hematopoietic tissue of the bone marrow.
Reticulocyte counts are valuable in determining if an anemia is regenerative (adequate bone marrow response) or nonregenerative (inadequate bone marrow response), as well as in identifying underlying occult compensated hemolytic processes.
Reticulocytes with sufficient RNA in the cytoplasm can be identified in a peripheral blood film stained with a standard Romanovsky stain, including most quick stains used in practice.
www.idexx.com /animalhealth/education/diagnosticedge/200401.jsp   (1937 words)

  
 Anemias: Currents: UI Health Care
The reticulocyte count is expressed as a percentage of total cells counted and must be corrected to a total number of reticulocytes per microliter.
Reticulocyte counts that are normal or low (in the face of anemia) are suggestive of the inability of the bone marrow to respond to anemia (marrow failure).
Reticulocyte hemoglobin content may be a more accurate reflection of bone marrow iron stores and is a promising technology.
www.uihealthcare.com /news/currents/vol5issue4/03anemia.html   (2220 words)

  
 Anemia and aplastic
True aplastic crisis with very low reticulocyte count and only anemia is usually seen in children and associated with infection by the parvovirus B19.
When the anemia is stable and the reticulocyte count is at the patient’s normal level, discharge with less frequent monitoring is indicated.
Hemoglobin levels, reticulocyte counts, indirect bilirubin, and LDH should be determined on a regular basis during health maintenance to establish a baseline for each patient which will usually be relatively stable.
www.scinfo.org /anemia.htm   (2008 words)

  
 Medicare: RETICULOCYTE COUNTS   (Site not responding. Last check: 2007-10-16)
The reticulocyte count is therefore usually corrected for the anemia by multiplying the measured percentage (reticulocyte count) by the ratio of the patient's hematocrit against a normal hematocrit.
INDICATIONS and LIMITATIONS OF COVERAGE: The reticulocyte count is indicated in the evaluation of unexplained anemia and may be useful in the evaluation of the response to therapeutic intervention.
A reticulocyte count is not considered as a component of a complete blood count and routine screening studies are excluded from Medicare coverage.
library.umsmed.edu /medi-retic.html   (469 words)

  
 Reticulocyte Count
Reticulocytes circulate in the bloodstream for about 2 days before developing into mature red blood cells.
The reticulocyte count increases during rapid blood loss or in the course of certain diseases in which red blood cells are destroyed prematurely.
For example, a higher reticulocyte count indicates that iron replacement treatment or other treatment to reverse the anemia is effective.
www.webmd.com /a-to-z-guides/Reticulocyte-Count   (593 words)

  
 Reconstitution of the Steroid Receptor·hsp90 Heterocomplex Assembly System of Rabbit Reticulocyte Lysate -- Dittmar et ...
The GR must be associated with hsp90 for it to bind steroid (8), and conversion of the GR to a steroid binding form constitutes a rapid assay for heterocomplex assembly (4, 9).
Reticulocyte lysate was depleted of hsp70 by extraction of hsp70 onto a matrix of ATP-agarose exactly as described by Hutchison et al.
The components of the rabbit reticulocyte receptor·hsp90 heterocomplex assembly system were identified by analyzing the proteins that were bound to the chicken progesterone receptor (PR) at early and late stages of assembly of the PR·hsp90 heterocomplex (10, 12, 14, 19).
www.jbc.org /cgi/content/full/271/22/12833   (6463 words)

  
 Pathology
It is possible to count reticulocytes by precipitating the residual RNA using new methylene blue to form a reticular network in the cell.
The increased reticulocyte count would indicate that her marrow is responding with acclerated erythropoiesis.
You decided that the 44 year -old woman with a hematocrit of 0.15 and a reticulocyte count of 2% had an increased reticulocyte count indicating that her marrow is responding with increased RBC production thus you decide to watch and wait.
www.med-ed.virginia.edu /courses/path/innes/nh/normbasics2.cfm   (831 words)

  
 Reticulocyte Count in Cats
A reticulocyte count is a measure of the number of reticulocytes circulating in the blood.
In the presence of anemia, a low reticulocyte count indicates that the body does not recognize the anemia and is not trying to correct the situation.
On the other hand, a high reticulocyte count indicates that the body does recognize the anemia and is responding by releasing the immature cells and “regenerating new cells”.
www.petplace.com /cats/reticulocyte-count-in-cats/page1.aspx   (674 words)

  
 Pathology
An increased reticulocyte count indicates loss or destruction of RBCs, with an appropriate bone marrow response, as in hemorrhage or hemolysis.
Reticulocytes circulate for about 1 day before they contain all their hemoglobin and are called erythrocytes.
His corrected reticulocyte count is not as abnormal as the observed reticulocyte count might suggest.
www.mcl.tulane.edu /classware/pathology/Krause/Notes/HAnemia.html.1   (1324 words)

  
 WRAL.com - Health Encyclopedia - Reticulocyte Count   (Site not responding. Last check: 2007-10-16)
This is a test that measures the percentage of reticulocytes (slightly immature red blood cells) in blood.
A lower-than-normal percentage of reticulocytes usually indicates a nutritional deficiency.
The reticulocyte count may be increased during pregnancy.
www.wral.com /encyclopedia/6864700/detail.html   (699 words)

  
 Flow cytometric reticulocyte analysis and the reticulocyte maturity index.   (Site not responding. Last check: 2007-10-16)
Reticulocyte analysis has evolved to one of the accepted and routinely practiced clinical applications of flow cytometry technology.
The ability to FCM instruments to quantitate fluorescence intensity has been utilized to derive a parameter of reticulocyte maturity, which we have termed the reticulocyte maturity index.
FCM reticulocyte analysis is still not fully mature, but is in a state of continued evolution.
www.arclab.org /medlineupdates/abstract_8494215.html   (195 words)

  
 Channel3000.com - Health Encyclopedia - Reticulocyte Count
Blood is drawn from a vein, usually from the inside of the elbow or the back of the hand.
A special stain can be used to identify reticulocytes, because they contain a substance called RNA, while fully mature red blood cells do not.
The number of reticulocytes in the blood indicates how quickly they are being produced and released by the bone marrow.
www.channel3000.com /encyclopedia/6864700/detail.html   (634 words)

  
 Optimize Your TNT(R) Reticulocyte Lysate Systems Reaction-eNotes
To maximize protein yield, the rabbit reticulocyte lysate in each of these systems is supplemented with the components needed for efficient transcription and translation, such as magnesium and potassium ions, NTPs and calf liver tRNA, and is tested for efficient transcription and translation.
Coupled Reticulocyte Lysate reaction to avoid degradation of the in vitro transcripts and a reduction in protein yields.
Coupled Reticulocyte Lysate Systems provide potassium and magnesium concentrations near these values, and for most templates, there is little advantage of adding additional potassium and magnesium to the reaction.
www.promega.com /enotes/applications/ap0058_tabs.htm   (2361 words)

  
 Reticulocyte hemoglobin detects iron deficit in infants American Family Physician - Find Articles   (Site not responding. Last check: 2007-10-16)
The authors of this study prospectively monitored 202 healthy infants nine to 12 months of age to compare reticulocyte hemoglobin content with hemoglobin in screening for iron deficiency.
The optimal cutoff level for detecting iron deficiency with reticulocyte hemoglobin content was 27.5 pg (sensitivity = 83 percent; specificity = 72 percent).
Bottom Line: A low reticulocyte hemogobin content has a higher sensitivity for the accurate detection of early iron deficiency in infants than a standard hemoglobin measurement.
www.findarticles.com /p/articles/mi_m3225/is_2_73/ai_n16088533   (405 words)

  
 The complete blood count and reticulocyte count--are they necessary in the evaluation of acute vasoocclusive ...
The complete blood count and reticulocyte count--are they necessary in the evaluation of acute vasoocclusive sickle-cell crisis?
the reticulocyte count in the evaluation of adult patients with acute
Full blood count and reticulocyte count in painful sickle crisis.
www.aemj.org /cgi/content/abstract/3/8/751   (363 words)

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