
	Where results make sense

Topic: Retinal pigment epithelium

	Retinal Physician
		Congenital hypertrophy of the RPE with halo superiorly and central depigmented lacuna.
		The retinal vessels within and overlying the lesion are often stretched or tortuous and are obscured by white fibroglial tissue at the level of the vitreoretinal interface.
		Adenocarcinoma arising from congenital hypertrophy of the retinal pigment epithelium.
	www.retinalphysician.com /article.aspx?article=100087 (1462 words)

	Retinal Pigment Epithelium (RPE) Detachment
		RPE detachment is a non-specific anatomical alteration that may result from any number of choroidal disorders that disrupt the normal junction between the basement membrane of the RPE and the inner collagenous layer of Bruch’s membrane.
		In cases of idiopathic RPE detachment, a striking similarity with ICSC is seen in the predisposed patient population; i.e.
		RPE detachment in patients over 55 years of age should be considered secondary to choroidal neovascular membrane, rather than idiopathic, until proven otherwise.
	www.revoptom.com /handbook/SECT42a.HTM (599 words)

	Retinal pigment epithelium - Wikipedia, the free encyclopedia
		The retinal pigment epithelium is the pigmented cell layer just outside the neurosensory retina that nourishes retinal visual cells, and is firmly attached to the underlying choroid and overlying retinal visual cells.
		The RPE is composed of a single layer of hexagonal cells.
		"Relative contributions of the neurosensory retina and retinal pigment epithelium to macular hypofluorescence." Arch Ophthalmol.
	en.wikipedia.org /wiki/Pigmented_layer (242 words)

	Evaluation and Management of Suspected Retinal Detachment - April 1, 2004 - American Family Physician
		Retinal detachment is relatively uncommon, affecting only one in 10,000 people per year, or approximately one in 300 patients in the course of a lifetime.
		Retinal detachment results when physiologic and anatomic mechanisms of retinal attachment are overcome and the retina separates from the underlying retinal pigment epithelium (Figure 1, lower right).
		The plane of separation in retinal detachment is between the retina and the retinal pigment epithelium.
	www.aafp.org /afp/20040401/1691.html (3346 words)

	Neural Retina Limits the Nonviral Gene Transfer to Retinal Pigment Epithelium in an In Vitro Bovine Eye Model
		Blood-retinal barrier is composed of the endothelia of retinal capillaries and retinal pigment epithelium (RPE).
		The RPE cells that were living before fixation were selected for analysis by gating; the dead RPE cells and the possible erythrocytes, photoreceptor outer segments, and pigment granules were excluded on the basis of their size and other scattering properties.
		Therefore, the transfer of oligonucleotide to the RPE may be slowed down by the protein binding and gradual release from the protein depot.
	aapspharmsci.org /view.asp?art=aapsj060325 (5213 words)

	[No title]
		Because it is located between the neural retina and the pigment epithelium, the IPM is in a strategic position to perform several important functions for the retina; the IPM appears to be involved in retinal nutrition, retinoid transport, and enzymatic digestion of shed outer-segment material.
		We have hypothesized that age-related macular degeneration (AMD) is an acquired lysosomal storage disease, caused by accumulation of lipofuscin in the retinal pigment epithelium (RPE).
		We are describing the relationships of the retinal vascular networks to the neuronal layers of monkey and human retinas and mapping the topography of retinal thickness to derive a three-dimensional picture of the fovea and other regions of the retina.
	www.eri.harvard.edu /training/retinal.html (3964 words)

	A novel function for Hedgehog signalling in retinal pigment epithelium differentiation -- Perron et al. 130 (8): 1565 ...
		RPE, with the overlying choroid and underlying non-pigmented epithelium,
		the pigmentation was abnormal, notably in the RPE (Fig.
		(A) A molecular gradient in the RPE of Xenopus tadpole embryos.
	dev.biologists.org /cgi/content/full/130/8/1565 (8734 words)

	The apical and basal environments of the retinal pigment epithelium regulate the maturation of tight junctions during ...
		RPE was isolated from E7 (A,B) and E14 (C,D) embryos and cultured with SF3 medium in the basal chamber and either SF3 (A,C) or rcSF3 (B,D) in the apical chamber.
		RPE was isolated from E7 (A,B), E10 (C,D) and E14 (E,F) embryos and cultured with SF2 medium in the basal chamber and either SF3 (A,C,E) or rcSF3 (B,D,F) in the apical chamber.
		RPE was isolated from E14 embryos and cultured with CEF medium in the basal chamber and either SF3 (A) or rcSF3 (B) in the apical chamber.
	jcs.biologists.org /cgi/content/full/117/15/3307 (7120 words)

	Cell Biology of the Retinal Pigment Epithelium
		The retinal pigment epithelium (RPE) plays a central role in retinal physiology by forming the outer blood-retinal barrier and supporting the function of the photoreceptors.
		These retinal factors differ from those that decrease the permeability of the monolayer, and may act indirectly through effects on the structure of the apical microvilli.
		In the photo above, the RPE monolayer is viewed en face with the tight junctions illuminated by fluorescent tags for the tight junction protein, ZO-1, and the subadjacent circumferential band of actin.
	info.med.yale.edu /surgery/anatomy/Rizzolo/rizzolo.html (1311 words)

	eMedicine - Retinal Detachment, Tractional : Article Excerpt by: Lihteh Wu, MD (Site not responding. Last check: 2007-10-29)
		RPE cells, glial cells, fibrocytes, macrophages, and collagen fibrils are important components of these membranes.
		It has been shown that the amount of RPE cells in the vitreous cavity correlates with the size of the retinal breaks.
		TRD may occur in a number of ocular pathologic conditions, such as proliferative diabetic retinopathy (PDR), sickling hemoglobinopathies, retinal venous obstructions, and retinopathy of prematurity (ROP), that are characterized by progressive retinal ischemia.
	www.emedicine.com /oph/byname/retinal-detachment-tractional.htm (623 words)

	Degenerative (Site not responding. Last check: 2007-10-29)
		Classically, clumps of pigment arising from the photoreceptor layer dispersed throughout the peripheral retina in a perivascular pattern, often assuming a " bone spicule " arrangement.
		Pigment spots that are often arranged in groups to resemble the footprints of animals, They are usually grouped in one sector of the fundus
		It is a degenerative disease of the vitreous of unknown cause.It is characterized by the development of white or yellow white spherical bodies composed of calcium soap within the collagen framework of the vitreous.
	www.yemenweb.com /algorafi/new_page_5.htm (940 words)

	Light-Evoked Responses of the Mouse Retinal Pigment Epithelium -- Wu et al. 91 (3): 1134 -- Journal of Neurophysiology
		apical membrane of the retinal pigment epithelium (RPE) (Oakley
		a hyperpolarization of the basal membrane of the RPE in response
		Retinal pigment epithelial cell contributions to the electroretinogram and electrooculogram.
	jn.physiology.org /cgi/content/full/91/3/1134 (5575 words)

	Ocular Transplantation, LLC - A Hope for Macular Degeneration (Site not responding. Last check: 2007-10-29)
		There are two types of cells that degenerate in retinal diseases, such as retinitis pigmentosa and macular degeneration: the nourishing cell layer called the retinal pigment epithelium; and the light-sensitive photoreceptor cells which are nourished by the retinal pigment epithelium.
		End of the 80's, it was shown by two different research groups that transplantation of healthy retinal pigment epithelium cells can "rescue" photoreceptors in animals with defective retinal pigment epithelium.
		Several research groups in the field have transplanted the retinal tissue as cell suspension, broken-up pieces or as intact sheets.
	www.retinaltransplantation.com /background.html (150 words)

	Age-related changes of glycosidases in human retinal pigment epithelium.
		This study was undertaken to determine whether there are age-related changes in the specific activities of several glycosidases in fresh retinal pigment epithelial cells (RPE) isolated from the posterior pole of human donor eyes.
		RPE cells were isolated from the posterior third of the retina using the conventional rush method and homogenized with a glass, Broeck tissue grinder.
		All post-nuclear supernatants were analyzed for glycosidase activity; a smaller number of nuclear pellets were assayed to verify that the majority of the enzyme activity was associated with the post-nuclear sypernatants.
	www.aegis.com /aidsline/1996/dec/M96C1125.html (543 words)

	eMedicine - Retinal Detachment, Exudative : Article Excerpt by: Lihteh Wu, MD (Site not responding. Last check: 2007-10-29)
		The direction of flow is influenced by the relative hyperosmolarity of the choroid with respect to the vitreous and the RPE that actively pumps ions and water from the vitreous into the choroid.
		For instance, certain pathological conditions are characterized by the presence of abnormal blood vessels that leak profusely.
		Damage to the RPE prevents the pumping action of fluid.
	www.emedicine.com /oph/byname/retinal-detachment-exudative.htm (468 words)

	Substrate specificity of retinyl ester hydrolase activity in retinal pigment epithelium -- Mata et al. 39 (3): 604 -- ...
		in the RPE and in the liver (12) (13).
		Abbreviations: REH, retinyl ester hydrolase; RPE, retinal pigment epithelium;
		Bridges, C. Vitamin A and the role of the pigment epithelium during bleaching and regeneration of rhodopsin in the frog eye.
	www.jlr.org /cgi/content/full/39/3/604 (4091 words)

	Iris pigment epithelium - Wikipedia, the free encyclopedia
		The iris pigment epithelium (IPE) is a two-cell thick layer of cuboidal cells lying behind the iris.
		The ciliary epithelium is continuous in its turn with the multilayered retina, which has an outermost pigmented layer, the retinal pigment epithelium (RPE).
		Despite their very different functions and histological appearances, these regions have a common origin from the two layers of the embryological optic cup, which is derived from the neural crest.
	en.wikipedia.org /wiki/Iris_pigment_epithelium (409 words)

	Macrophage and Retinal Pigment Epithelium Phagocytosis: Apoptotic Cells and Photoreceptors Compete for {alpha}v{beta}3 ...
		Macrophage and Retinal Pigment Epithelium Phagocytosis: Apoptotic Cells and Photoreceptors Compete for {alpha}v{beta}3 and {alpha}v{beta}5 Integrins, and Protein Kinase C Regulates {alpha}v{beta}5 Binding and Cytoskeletal Linkage -- Finnemann and Rodriguez-Boulan 190 (6): 861 -- The Journal of Experimental Medicine
		Bok, D., Hall, M.O. The role of the pigment epithelium in the etiology of inherited retinal dystrophy in the rat.
		Hall, M.O., Abrams, T.A. The phagocytosis of ROS by RPE cells is not inhibited by mannose-containing ligands.
	www.jem.org /cgi/content/full/190/6/861 (7991 words)

	Arch Ophthalmol -- Abstract: A New Model of Retinal Pigment Epithelium Transplantation With Microspheres, September ... (Site not responding. Last check: 2007-10-29)
		Arch Ophthalmol -- Abstract: A New Model of Retinal Pigment Epithelium Transplantation With Microspheres, September 1999, Oganesian et al.
		pigment epithelium cells, with a mild local inflammatory response.
		investigations in the area of retinal pigment epithelium transplantation.
	archopht.ama-assn.org /cgi/content/abstract/117/9/1192 (267 words)

	Dorsal Retinal Pigment Epithelium Differentiates as Neural Retina in the Microphthalmia (mi/mi) Mouse -- Bumsted and ...
		Dorsal Retinal Pigment Epithelium Differentiates as Neural Retina in the Microphthalmia (mi/mi) Mouse
		retinal histogenesis is dependent on the presence of a differentiated
		1A, arrows), in mi/mi RPE pigmentation was absent, and
	www.iovs.org /cgi/content/full/41/3/903 (3915 words)

	Vascular Endothelial Growth Factor Expression in the Retinal Pigment Epithelium Is Essential for Choriocapillaris ...
		ciliary pigment epithelium and of the ciliary margin of the
		Sarks JP, Sarks SH, Killingsworth MC: Evolution of geographic atrophy of the retinal pigment epithelium.
		Raymond SM, Jackson IJ: The retinal pigmented epithelium is required for development and maintenance of the mouse neural retina.
	ajp.amjpathol.org /cgi/content/full/167/5/1451 (4307 words)

	PARTICIPATION OF THE RETINAL PIGMENT EPITHELIUM IN THE ROD OUTER SEGMENT RENEWAL PROCESS -- Young and Bok 42 (2): 392 ...
		Bipolar assembly of caveolae in retinal pigment epithelium
		Degradation of extracellular ATP by the retinal pigment epithelium
		Mutation of the receptor tyrosine kinase gene Mertk in the retinal dystrophic RCS rat
	www.jcb.org /cgi/content/abstract/42/2/392 (1968 words)

	Fluorescence, aging, lipofuscin, human retinal pigment epithelium, rpe, autofluorescence (Site not responding. Last check: 2007-10-29)
		Ultraviolet (UV) excited pale yellow emission in retinal pigment epithelial (rpe) cells from 82 year old donor (original color photograph used for Stark et al., 1984 chapter).
		A scanning electron micrograph(SEM) which shows the association of the retinal pigment epithelial (rpe) cells with the rod cells in a fracture through a rat retina
		Demonstration of the orders-of-magnitude sensitivity error from spectrofluorometers which led researchers to be over 100 nm too short on the emission spectrum of lipofuscin (from Eldred et al., 1982)
	starklab.slu.edu /lipofuscin1.htm (413 words)

	Morphogenesis of the Retinal Pigment Epithelium: Toward Understanding Retinal Degenerative Diseases -- MARMORSTEIN et ...
		Morphogenesis of the Retinal Pigment Epithelium: Toward Understanding Retinal Degenerative Diseases -- MARMORSTEIN et al.
		or basolateral pathway in RPE cells cannot be predicted by the
		Proteomic Characterization of Isolated Retinal Pigment Epithelium Microvilli
	www.annalsnyas.org /cgi/content/abstract/857/1/1 (529 words)

	Protein Database, Human Retinal Pigment Epithelium -- West et al. 2 (1): 37 -- Molecular & Cellular Proteomics
		Protein Database, Human Retinal Pigment Epithelium -- West et al.
		The retinal pigment epithelium (RPE) is a single cell layer
		in retinal physiology and the biochemistry of vision.
	www.mcponline.org /cgi/content/abstract/2/1/37 (480 words)

Try your search on: Qwika (all wikis)