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	Retinoblastoma Treatment - National Cancer Institute
		Retinoblastoma is a disease in which malignant (cancer) cells form in the tissues of the retina.
		Retinoblastoma is sometimes caused by a gene mutation passed from the parent to the child.
		Retinoblastoma that is caused by an inherited gene mutation is called hereditary retinoblastoma.
	www.cancer.gov /cancerinfo/pdq/treatment/retinoblastoma/patient (892 words)

	DJO \| Digital Journal of Ophthalmology
		Retinoblastoma is a disease that causes the growth of malignant tumors in the retinal cell layer of the eye.
		It is important to remember that the retinoblastoma gene produces cancer in approximately 80 to 90 percent of patients who carry the gene and, therefore, about 40 percent of the patients' offsprings will have retinoblastoma, while some offspring may simply carry the gene and never develop the disease.
		Every case of retinoblastoma is unique, and the treatments, or combination of treatments, vary according to size, shape, and location of the tumor, whether both eyes are affected or not, and whether or not the tumor has spread (metastasis).
	www.djo.harvard.edu /site.php?url=/patients/pi/436 (2447 words)

	Retinoblastoma
		Retinoblastoma is a rare cancer of the retina (the innermost layer of the eye, located at the back of the eye, that receives light and images necessary for vision).
		In inherited retinoblastoma (40 percent of the cases), the first mutation is inherited from a parent, while the second occurs during the development of the retina.
		When retinoblastoma is diagnosed, tests will be performed to determine the size, number, location of the tumors, and if the tumors have spread to the other parts of the body.
	www.healthsystem.virginia.edu /uvahealth/peds_oncology/retino.cfm (1055 words)

	Retinoblastoma
		Retinoblastoma represents the phenotypic expression of an abnormal or absent tumor suppressor gene known as the retinoblastoma gene (RB1).
		Retinoma: spontaneous regression of retinoblastoma or benign manifestation of the mutation?
		Cutaneous malignant melanoma in survivors of heritable retinoblastoma.
	www.moffitt.org /moffittapps/ccj/v5n4/article2.html (3239 words)

	Retinoblastoma: (Site not responding. Last check: 2007-11-05)
		Retinoblastoma is a relatively uncommon tumor of childhood that arises in the retina and accounts for about 3% of the cancers occurring in children younger than 15 years.
		Trilateral retinoblastoma is a well-recognized syndrome that consists of unilateral or bilateral germline retinoblastoma associated with an intracranial neuroblastic tumor.
		Intraocular retinoblastoma is localized to the eye and may be confined to the retina or may extend to involve the globe; however, it does not extend beyond the eye into the tissues around the eye or to other parts of the body.
	www.acor.org /cnet/62846.html (5484 words)

	Retinoblastoma - Genetics Home Reference
		Retinoblastoma is a rare type of eye cancer that develops in the retina, the part of the eye that detects light and color.
		Retinoblastoma is a chromosomal condition related to chromosome 13.
		A person with retinoblastoma may inherit an altered copy of the gene from one parent, or the altered gene may be the result of a new mutation.
	ghr.nlm.nih.gov /condition=retinoblastoma (876 words)

	Retinoblastoma Encyclopedia of Medicine - Find Articles
		Retinoblastoma is a rare childhood cancer of the eye.
		Retinoblastoma is a malignant tumor which usually appears in infants or young children.
		Treatment for retinoblastoma depends on the size and number of tumor locations (foci) in the eye, as well as whether the disease is found in one or both eyes.
	www.findarticles.com /p/articles/mi_g2601/is_0011/ai_2601001188 (785 words)

	Encyclopedia - Retinoblastoma
		Retinoblastoma is the most common eye cancer of children, occurring in one of every 20,000 births.
		Retinoblastoma is often an inherited condition, although it can occur without a family history.
		If retinoblastoma occurs in one child, young brothers and sisters should be observed for signs of the cancer.
	www.visionrx.com /library/enc/enc_retinoblast.asp (394 words)

	Retinoblastoma: Definition, Symptoms, and Treatment - Kellogg Eye Center
		Retinoblastoma is a malignant (cancerous) tumor of the retina.
		Retinoblastoma is usually confined to the eye but, if left untreated, will spread to nearby tissues and other parts of the body.
		If your child has retinoblastoma, particularly the hereditary type, there is an increased chance that he or she may develop a second cancer in later years.
	www.kellogg.umich.edu /patientcare/conditions/retinoblastoma.html (679 words)

	Retinoblastoma
		Retinoblastoma (RB) is a malignant tumor of the developing retina that occurs in children, usually before the age of five years.
		Predispositon to retinoblastoma is caused by germline mutations in the
		In those individuals with a family history of retinoblastoma and in uncommon circumstances in which the child presents with strabismus or poor vision, the retinal tumors may be small and can be seen on clinical examination not to affect the optic nerve or extend outside the retina.
	www.geneclinics.org /profiles/retinoblastoma/details.html (3867 words)

	Retinoblastoma (Site not responding. Last check: 2007-11-05)
		Retinoblastoma is a malignant tumor of the retina, which is a thin membrane on the back of the eye that works like a camera, taking pictures of what you see.
		Retinoblastoma also has the potential to spread throughout the retina, into the eye tissue under the retina, into the eye socket, the optic nerve and brain, or more distantly, to the bones and the bone marrow.
		Retinoblastoma serves as the model for understanding the heredity and genetics of childhood cancer.
	www.stjude.org /disease-summaries/0,2557,449_2167_3003,00.html (1041 words)

	Retinoblastoma
		Retinoblastoma is a childhood cancer that occurs in the retina.
		Most cases of retinoblastoma are diagnosed before the age of five by a doctor called an ophthamologist, which is a doctor specializing in the eye.
		Retinoblastoma of both eyes is usually diagnosed at a younger age than cases involving only one eye.
	www.hmc.psu.edu /childrens/healthinfo/r/retinoblastoma.htm (766 words)

	Retinoblastoma
		Retinoblastoma is a relatively uncommon tumor of childhood that arises in the retina.[2] The estimated annual incidence is between 1 in 15,000 and 1 in 34,000.
		Retinoblastoma is a tumor that occurs in hereditary (40%) and nonhereditary (60%) forms.
		Patients with the hereditary type of retinoblastoma have a markedly increased frequency of additional malignancies.[9] The cumulative incidence is about 26 +/-10% in nonirradiated and 58 +/-10% in irradiated patients by 50 years after diagnosis of retinoblastoma.[10] Most of the excess cancers were osteosarcomas, soft tissue sarcomas, or melanomas.
	www.uoc.muni.cz /guidelines/1deti/RETINOBL.htm (2190 words)

	Retinoblastoma American Family Physician - Find Articles
		Retinoblastoma, a neuroblastic tumor, is the most common primary intraocular malignancy of childhood.
		The retinoblastoma gene is a tumor suppressor gene, located on the long arm of chromosome 13 at region 14, that codes for the RB protein.
		Approximately 60 percent of retinoblastoma occurrences are secondary to somatic, nonhereditary mutations.
	www.findarticles.com /p/articles/mi_m3225/is_6_73/ai_n16119207 (839 words)

	Retinoblastoma - WrongDiagnosis.com
		Seventy-five percent of retinoblastomas are unilateral; 60% occur sporadically.
		Retinoblastoma is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH).
		Retinoblastoma is usually confined to the eye but can spread to the brain via the optic nerve.
	www.wrongdiagnosis.com /r/retinoblastoma/intro.htm (851 words)

	Eye Conditions > Retinoblastoma -- EyeMDLink.com
		Retinoblastoma is the most common intraocular malignancy of childhood.
		The average age at diagnosis is 15 months for patients with bilateral retinoblastomas and 24 months for patients with unilateral retinoblastomas.
		Retinoblastoma may also occur in the brain (pinealoblastoma), although this is rare and almost uniformly fatal.
	www.eyemdlink.com /Condition.asp?ConditionID=392 (468 words)

	Retinoblastoma and Your Child’s Eyes
		Retinoblastoma is a malignant tumor on the retina, the light-sensing part of the eye, and is highly curable if treated early.
		About 40% of all cases of retinoblastoma are inherited, meaning the cancer is passed on from parent to child.
		Retinoblastoma occurs about 75% of the time in one eye, and 25% of the time in both eyes.
	www.webmd.com /content/article/63/72013.htm (861 words)

	eMedicine - Retinoblastoma : Article by Marichelle L Aventura, MD (Site not responding. Last check: 2007-11-05)
		Causes: Retinoblastoma is caused by the so-called retinoblastoma gene, which is a mutation in the long arm of chromosome 13.
		Retinoblastomas also may arise by hypermethylation of the promoter region of the retinoblastoma gene, which deactivates this gene but does not alter the DNA sequence.
		Retinoblastoma is a rare but extremely important disease to the ophthalmologist since its misdiagnosis is one of the few errors in the practice of ophthalmology that can lead to the death of a child.
	www.emedicine.com /oph/topic346.htm (7063 words)

	Retinoblastoma
		Retinoblastoma (RB) is the most common eye cancer in children and it can be inherited.
		Although the most common eye cancer in children, retinoblastoma is quite rare and occurs in approximately 1 in every 20,0000 births.
		The goal with retinoblastoma is early detection to maximize the visual outcome and the quality of life of the affected child.
	www.retinoblastoma.ca (262 words)

	Sloan-Kettering - Retinoblastoma
		Retinoblastoma, the most common type of eye tumor seen in children, occurs most often in young children before the age of five and affects boys and girls in equal numbers.
		Retinoblastoma affects one in every 15,000 to 30,000 live babies born in the United States and is found in boys and girls from all backgrounds.
		Our treatment of retinoblastoma is customized for each patient, and depends upon the age of the child, the involvement of one or both eyes, and whether or not the cancer has spread to other parts of the body.
	www.mskcc.org /mskcc/html/2867.cfm (500 words)

	Retinoblastoma
		Retinoblastoma is an extremely rare malignant tumor that develops in the nerve-rich layers that line the back of the eyes (retina).
		The most typical finding associated with retinoblastoma is the reflection of light off a tumor behind the lens of the eye, which causes the pupil to appear white, the so called "cat’s eye reflex" (leukokoria).
		The presence of a retinoblastoma may cause a rise in the pressure in the eyeball (glaucoma).
	www.webmd.com /hw/vision/nord289.asp (454 words)

	Retinoblastoma - My Child Has - Children's Hospital Boston
		Retinoblastoma can occur in either eye, however, in about 25 to 30 percent of the cases, the tumor is present in both eyes.
		Retinoblastoma cells can, in rare cases, spread (metastasize) to other areas of the body, including the bone marrow.
		Sporadic means "occurs by chance." Retinoblastoma occurs due to mutations in a tumor suppressor gene (called RB1) located on chromosome #13.
	www.childrenshospital.org /az/Site1523/mainpageS1523P0.html (1845 words)

	MedlinePlus Medical Encyclopedia: Retinoblastoma
		Retinoblastoma is a malignant tumor (cancer) of the retina (part of the eye) that generally affects children under the age of 6.
		Retinoblastoma occurs when a cell of the growing retina develops a mutation in the RB gene (a tumor-suppressor gene).
		Call your health care provider if signs or symptoms of retinoblastoma are present, especially if your child's eyes look abnormal or appear abnormal in photographs.
	www.nlm.nih.gov /medlineplus/ency/article/001030.htm (607 words)

	Retinoblastoma
		Retinoblastoma is a rare tumour of the eye which develops in the cells of the retina, most patients are under 5 years old.
		Retinoblastoma Society, The (UK) A national organisation providing support and information for people with retinoblastoma and their families.
		Retinoblastoma (USA) Part of a SEER report on cancer incidence and survival among children and adolescents; 1975-1995.
	www.cancerindex.org /ccw/guide2r.htm (1079 words)

	Retinoblastoma
		In fact, retinoblastoma was one of the first cancers recognized as "hereditary".
		They found that deletions or mutations of the "retinoblastoma" gene within the q14 band of chromosome 13 are highly associated with a predisposition to retinoblastoma.
		Retinoblastoma is treated by surgery (enucleation), chemotherapy, cryotherapy, light coagulation, and radiation.
	www.acor.org /ped-onc/diseases/retino.html (505 words)

	Retinoblastoma
		Retinoblastoma is usually confined to the eye and does not spread to nearby tissue or other parts of the body.
		This is called trilateral retinoblastoma, and patients should be periodically monitored by the doctor for the possible development of this rare condition during and after treatment.
		If your child has retinoblastoma, particularly the hereditary type, there is also an increased chance that he or she may develop other types of cancer in later years.
	cancerweb.ncl.ac.uk /cancernet/200993.html (1761 words)

	Retinoblastoma - Wikipedia, the free encyclopedia
		Retinoblastoma may occur on the basis of a hereditary (genetically inherited) predisposition.
		Children with non-hereditary form of retinoblastoma, which is present in about half of all patients, develop tumors in one eye only (unilateral retinoblastoma).
		Hereditary retinoblastoma is caused by an inherited mutation in a single copy of the RB1-gene thus resulting in a heterozygous individual.
	en.wikipedia.org /wiki/Retinoblastoma (627 words)

	Retinoblastoma
		Retinoblastoma is a rare cancer of the eye.
		It may be hereditary, and one-third of the cases involve both eyes.
		Retinoblastoma often can be seen by looking at the young person's eye but is usually diagnosed by an examination under general anesthesia using an ophthalmoscope, an instrument used in examining the interior of the eye.
	healthlink.mcw.edu /article/926232702.html (247 words)

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