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Topic: Rhinovirus

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	Rhinovirus - Wikipedia, the free encyclopedia
		Human rhinovirus A (HRV-A) Human rhinovirus B (HRV-B) Rhinovirus (from the Greek rhin-, which means "nose") is a genus of the Picornaviridae family of viruses.
		Interferon-alpha used intranasally was shown to be protective to rhinovirus infections.
		Rhinovirus: an unstoppable cause of the common cold?
	en.wikipedia.org /wiki/Rhinovirus (690 words)

	Rhinovirus Infection Induces Expression of Its Own Receptor Intercellular Adhesion Molecule 1 (ICAM-1) via Increased ...
		Rhinovirus Induces ICAM-1 Cell Surface Protein Expression in A549 Cells and in Primary Bronchial Epithelial Cells-- Preliminary studies indicated that rhinovirus infection of A549 cells up-regulated ICAM-1 surface expression at 8 h postinoculation.
		Rhinovirus infection of A549 respiratory epithelial cells induced a significant up-regulation of ICAM-1 surface expression at multiplicities of infection of 0.5, 1, and 2, with peak induction occurring at an MOI of 1.
		rhinovirus serotypes and that the induction was not receptor-restricted.
	www.jbc.org /cgi/content/full/274/14/9707 (7640 words)

	CDC - Epidemiology and Prevention of Pediatric Viral Respiratory Infections in Health-Care Institutions
		Although nosocomial rhinovirus infection is not as substantial a problem as RSV and influenza on pediatric wards, it can have serious sequelae in premature neonates and children with chronic diseases or immunosuppression (32).
		The Virginia group demonstrated that adults with experimental rhinovirus colds readily contaminated their hands and that rhinovirus could be recovered from 43% of plastic tiles they touched with their contaminated fingers (39).
		Adults with natural rhinovirus colds contaminated their hands in 39% of cases, and virus was found on 6% of objects in their homes (35,40).
	www.cdc.gov /ncidod/eid/vol7no2/goldmann.htm (3897 words)

	CDC - Respiratory Picornaviruses and Respiratory Syncytial Virus as Causative Agents of Acute Expiratory Wheezing in ...
		In infants, RSV was found in 54% and respiratory picornaviruses (rhinovirus and enteroviruses) in 42% of the cases.
		Rhinovirus was cultivated in 25 (38%) of 65 specimens with PCR-positive results, enteroviruses in 14 (24%) of 59 specimens with PCR-positive results, and rhino/enterovirus in 1 (2%) of 46 specimens with PCR-positive results.
		Detection of rhinovirus, respiratory syncytial virus, and coronavirus infections in acute otitis media by reverse transcriptase polymerase chain reaction.
	www.cdc.gov /ncidod/eid/vol10no6/03-0629.htm (3623 words)

	Rhinovirus
		Rhinovirus has also been implicated in causing bronchitis and is the virus most often seen in attacks of asthma.
		Rhinovirus will not grow if the temperature varies a few degrees.
		For now the best cure is to get plenty of fluids and take over the counter medications such as nasal decongestants, antihistamines, and analgesics.
	web.umr.edu /~microbio/BIO221_1998/rhinovirus.html (383 words)

	Drug Development Technology - RUPINTRIVIR - EXPERIMENTAL TREATMENT FOR THE COMMON COLD
		Rhinovirus infection is the most common cause of colds, producing the classic symptoms of a runny nose, blocked sinuses, headache and cough.
		Rhinovirus infections can be more serious in patients suffering from chronic respiratory diseases, triggering acute exacerbations of asthma, emphysema and chronic obstructive pulmonary disease (COPD).
		In May 2003 scientists in Germany discovered that the coronavirus implicated in SARS possess similar protease enzymes to those seen in rhinovirus and raised the intriguing prospect that protease inhibitors might be effective against this new disease.
	www.drugdevelopment-technology.com /projects/ag7088/index.html (745 words)

	Association of Rhinovirus Infections with Asthma -- Gern and Busse 12 (1): 9 -- Clinical Microbiology Reviews
		Rhinovirus inhalation causes long-lasting excessive airway narrowing in response to methacholine in asthmatic subjects in vivo.
		Comparison of standard virology and PCR in diagnosis of rhinovirus and respiratory syncytial virus infections in nasal aspirates from children hospitalized with wheezing illness and bronchiolitis.
		Rhinovirus stimulation of interleukin-6 in vivo and in vitro.
	cmr.asm.org /cgi/content/full/12/1/9 (6682 words)

	The Science Creative Quarterly » RHINOVIRUS: AN UNSTOPPABLE CAUSE OF THE COMMON COLD
		The route of entry for rhinovirus is via the upper respiratory tract.
		Rhinovirus is made up of a protein capsid with a genome of one strand of RNA.
		A proposed mechanism for the infection of cells with rhinovirus.
	www.scq.ubc.ca /?p=438 (1479 words)

	Medical Dictionary: Rhinovirus - WrongDiagnosis.com
		Rhinovirus (medical condition): A class of viruses commonly causing the common cold.
		Rhinovirus: genus of viruses comprising the common cold viruses.
		Rhinovirus : genus of viruses comprising the common cold viruses.
	www.wrongdiagnosis.com /medical/rhinovirus.htm (203 words)

	Rhinovirus infection induces mucus hypersecretion -- Yuta et al. 274 (6): 1017 -- AJP - Lung Cellular and Molecular ...
		Rhinovirus 39 infection in allergic and nonallergic subjects.
		Effect of experimental rhinovirus 16 colds on airway hyperresponsiveness to histamine and interleukin-8 in nasal lavages in asthmatic subjects in vivo.
		Effect of rhinovirus 39 (rv-39) infection on immune and inflammatory parameters in allergic and non-allergic subjects.
	ajplung.physiology.org /cgi/content/full/274/6/L1017 (3693 words)

	A Rhinovirus Outbreak among Residents of a Long-Term Care Facility -- Wald et al. 123 (8): 588 -- Annals of Internal ...
		Epidemiology of infections with rhinovirus types 43 and 55 in a group of University of Wisconsin student families.
		Rhinovirus and influenza type A infections as precipitants of asthma.
		Rhinovirus infection in acute exacerbations of chronic bronchitis: a controlled prospective study.
	www.annals.org /cgi/content/full/123/8/588 (3825 words)

	Low Grade Rhinovirus Infection Induces a Prolonged Release of IL-8 in Pulmonary Epithelium -- Johnston et al. 160 (12): ...
		Rhinovirus induced increased expression of IL-8 mRNA in A549 cells, which was clearly visible at 1, 3, and 24 h after inoculation.
		Rhinovirus type 9 was inoculated at an MOI of 1 onto A549 cells and adsorbed for 30 min.
		Detection of rhinovirus infection of the nasal mucosa by oligonucleotide in-situ hybridisation.
	www.jimmunol.org /cgi/content/full/160/12/6172 (7348 words)

	AAAAI - Media Center: JACI Highlights: Rhinovirus infections in infancy may predict development of persistent wheezing
		Rhinovirus infections in infancy may predict development of persistent wheezing
		Rhinovirus infections occur more commonly in fall and spring, and their findings convincingly demonstrate that 63% of infants who wheezed during these seasons continued to wheeze in the third year of life compared to only 20% of all other infants.
		Thus, infants who wheeze with respiratory infections during rhinovirus seasons should be followed closely during early childhood so that therapy can be instituted both acutely and/or or chronically that may help reduce the frequency and/or severity of any future wheezing episodes.
	www.aaaai.org /media/jaci/2005/09/rhinovirus.stm (135 words)

	Rhinovirus
		West Lafayette, IND (4/13/98)- The determination of the three-dimensional structure the receptor used by the rhinovirus could lead to the long-sought treatment for the common cold.
		The current research reveals that the rhinovirus bypasses the structure ICAM-1 uses to bind to white blood cells, and binds instead to another part of the receptor to gain entry into the cell, says Jordi Bella, a postdoctoral researcher working with Rossmann on the study.
		While the new findings could lead to ways to slow down rhinovirus infection, it may not slow down the 30% of colds caused by other viruses, he added.
	www.accessexcellence.org /WN/SUA12/rhino498.html (688 words)

	Efficacy of Organic Acids in Hand Cleansers for Prevention of Rhinovirus Infections -- Turner et al. 48 (7): 2595 -- ...
		Rhinovirus type 39 was used for these studies.
		in a reduction in the incidence of rhinovirus infection in the
		Inactivation of rhinovirus on human fingers by virucidal activity of glutaric acid.
	aac.asm.org /cgi/content/full/48/7/2595 (3277 words)

	Human rhinovirus (HRV)
		The type strain of the genus is human rhinovirus type A (HRV-1A).
		Along with other members of the family Picornaviridae, the HRV are unenveloped viruses with a positive sense, single-stranded RNA genome that is preceded by a genome-linked proteoin (5' VPg) and terminated with a poly(A) tract (3').
		Schematic representation of the human rhinovirus (HRV) (+)ssRNA genome.
	www.uq.edu.au /vdu/VDURhinovirus.htm (104 words)

	Laboratory Diagnosis of Rhinoviruses Infection, Rhinovirus Diagnosis
		The diversity of rhinovirus serotypes and the lack of cross-protection during reinfection with heterologus serotypes makes prevention by vaccination unlikely to succeed.
		Attention has therefore focused on the development of antiviral molecules such as interferons and synthetic anti- rhinovirus compounds which could be used therapeutically as well as prophylactically.
		One of these compounds, R61837 was shown to be effective in vivo when it significantly suppressed the appearance of colds in volunteers given this compound prophylactically.
	www.virology-online.com /viruses/CORZA3.htm (1117 words)

	Rhinovirus
		To begin the study, people with colds were recruited to spend 5 hours awake in hotel rooms before going to bed and 2 awake hours in their rooms the next morning.
		Thirty five percent of the objects had residual virus, demonstrating that people with colds do not have to be present for their germs to linger.
		The RNA of rhinovirus is surrounded by proteins that help it bind to other cells.
	www.healthsystem.virginia.edu /internet/news/archives06/rhinovirus.cfm (617 words)

	Inhibition of Nuclear Import and Alteration of Nuclear Pore Complex Composition by Rhinovirus -- Gustin and Sarnow 76 ...
		in the cytoplasm of cells infected with rhinovirus.
		mock infected or infected with rhinovirus for 6 h.
		Cells were either uninfected (mock infected) or infected with rhinovirus for 6 h (rhinovirus infected).
	jvi.asm.org /cgi/content/full/76/17/8787 (7150 words)

	Virucidal hand treatments for prevention of rhinovirus infection -- Turner and Hendley 56 (5): 805 -- Journal of ...
		Rhinovirus infections are the most frequent cause of common
		During a rhinovirus cold, virus replicates primarily in the
		Rhinovirus inactivation by aqueous iodine in vitro and on skin.
	jac.oxfordjournals.org /cgi/content/full/56/5/805 (1588 words)

	Role of p38 Mitogen-Activated Protein Kinase in Rhinovirus-Induced Cytokine Production by Bronchial Epithelial Cells -- ...
		The role of oxidative stress in rhinovirus induced elaboration of IL-8 by respiratory epithelial cells.
		Rhinovirus infection of primary cultures of human tracheal epithelium: role of ICAM-1 and IL-1ß.
		Rhinovirus induces major histocompatibility complex class I and costimulatory molecule up-regulation on respiratory epithelial cells.
	www.jimmunol.org /cgi/content/full/165/9/5211 (6523 words)

	Effects of Rhinovirus Infection on Hydrogen Peroxide- induced Alterations of Barrier Function in the Cultured Human ...
		Effects of Rhinovirus Infection on Hydrogen Peroxide- induced Alterations of Barrier Function in the Cultured Human Tracheal Epithelium -- OHRUI et al.
		A consistent observation is that rhinovirus infection is not cytotoxic for human tracheal epithelial cells, in that cell viability
		Infection of a human respiratory epithelial cell line with rhinovirus: induction of cytokine release and modulation of susceptibility to infections by cytokine exposure.
	ajrccm.atsjournals.org /cgi/content/full/158/1/241 (4401 words)

	Antigenic Variation Strategy of rhinoviruses
		While each virus serotype does not exhibit much variability other than the antigenic drift due to genomic replication, the rhinovirus group as a whole includes over 100 different serotypes.
		Rhinovirus 14, as solved by cryo-electron microscopy and image reconstruction.
		Rhinovirus 14, radially depth cued with anitgenic sites highlighted, as solved by X-ray crystallography.
	www.brown.edu /Courses/Bio_160/Projects1999/av/rhinovirus.html (131 words)

	Nitric Oxide Inhibits Rhinovirus-Induced Granulocyte Macrophage Colony-Stimulating Factor Production in Bronchial ...
		Human rhinovirus (HRV) infections are the predominant cause of the common cold and have been associated with exacerbations
		that rhinovirus infections induce asthma exacerbations by increasing
		Rhinovirus stimulation of interleukin-6 in vivo and in vitro: evidence for nuclear factor
	ajrcmb.atsjournals.org /cgi/content/full/24/3/317 (5976 words)

	Rhinovirus 16 3C Protease Induces Interleukin-8 and Granulocyte-Macrophage Colony-Stimulating Factor Expression in ... (Site not responding. Last check: 2007-10-29)
		Rhinovirus 16 3C Protease Induces Interleukin-8 and Granulocyte-Macrophage Colony-Stimulating Factor Expression in Human Bronchial Epithelial Cells -- FUNKHOUSER et al.
		Subauste MC, Jacoby DB, Richards SM, Proud D 1995 Infection of a human respiratory epithelial cell line with rhinovirus: induction of cytokine release and modulation of susceptibility to infection by cytokine exposure.
		Garofalo R, Sabry M, Jamaluddin M, Yu RK, Casola A, Ogra PL, Brasier AR 1996 Transcriptional activation of the interleukin-8 gene by respiratory syncytial virus infection in alveolar epithelial cells: nuclear translocation of the RelA transcription factor as a mechanism producing airway mucosal inflammation.
	www.pedresearch.org /cgi/content/full/55/1/13 (3472 words)

	Rhinovirus infection of primary cultures of human tracheal epithelium: role of ICAM-1 and IL-1beta -- Terajima et al. ...
		Rhinovirus infection of primary cultures of human tracheal epithelium: role of ICAM-1 and IL-1beta -- Terajima et al.
		Detection of rhinovirus RNA and cytokine mRNA by reverse transcription-polymerase chain reaction.
		For rhinovirus and each cytokine, mRNA expressions in human tracheal epithelial cells were examined before and at 1, 3, and
	ajplung.physiology.org /cgi/content/full/273/4/L749 (6250 words)

	Rhinovirus - WrongDiagnosis.com
		A class of viruses commonly causing the common cold.
		More detailed information about the symptoms, causes, and treatments of Rhinovirus is available below.
		You may also want to research other symptoms in our Symptoms Center.
	www.wrongdiagnosis.com /r/rhinovirus/intro.htm (237 words)

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