| | Genome Biology | Full text | The rhomboids: a near ubiquitous family of intramembrane serine proteases evolved via ... |
 | | Although the near universal presence of the rhomboid family in bacteria, archaea and eukaryotes appears to suggest that this protein is part of the heritage of the last universal common ancestor, phylogenetic tree analysis indicates bacterial origin with subsequent dissemination via horizontal gene transfer. |
 | | Rhomboids are missing in the microsporidium Encephalitozoon cuniculi, a eukaryotic intracellular parasite with a highly degraded genome, the archaea Methanothermobacter thermoautotrophicus and Thermoplasma volcanium, and several bacterial species, primarily parasites with small genomes but also species with moderate-size genomes, such as Xylella fastidiosum (see COG0705 at http://www.ncbi.nlm.nih.gov/COG/). |
 | | The phylogenetic tree of the rhomboid family tree shown in Figure 2 clearly follows neither the "standard model" scenario [22,23], with the major split between the archaeo-eukaryotic and bacterial lineages nor the "mitochondrial" scenario, which postulates acquisition of a gene by eukaryotes from the pro-mitochondrial endosymbiont. |
| genomebiology.com /2002/3/11/preprint/0010 (3961 words) |