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Topic: Ribavirin

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	Hepatitis C: Current Treatment
		The addition of ribavirin to interferon alpha is superior to interferon alpha alone in the treatment of chronic hepatitis C. Ribavirin is a synthetic nucleoside that has activity against a broad spectrum of viruses.
		In several studies, oral ribavirin was examined as a single agent for the treatment of adults with chronic hepatitis C. Although decreases in serum ALT activities were seen with treatment, the overall results of these studies were discouraging as sustained-responses were rarely achieved.
		Ribavirin is associated with a significant risk of abnormal fetal development and women of childbearing potential should not begin therapy until a report of a negative pregnancy test has been obtained and not become pregnant during treatment.
	cpmcnet.columbia.edu /dept/gi/ribavirin.html (1691 words)

	Encyclopedia: Ribavirin (Site not responding. Last check: 2007-10-18)
		The primary serious adverse effect of ribavirin is hemolytic anemia, which may worsen preexisting cardiac disease.
		Due to its effect on genetic material, significant teratogenic effects have been noted in all animal species on which ribavirin has been tested.
		Therefore, two simultaneous forms of birth control are recommended during treatment of either partner and continued for six months after treatment.
	www.nationmaster.com /encyclopedia/Ribavirin (666 words)

	Simple FactSheet: ribavirin (Copegus, Rebetol, Ribasphere)
		Ribavirin is approved for use in combination with pegylated interferon to treat hepatitis C (HCV) infection.
		Ribavirin used alone does not have any effect on HCV or HIV, but it helps pegylated interferon to be more effective.
		Ribavirin should not be taken with didanosine (Videx) due to the risk of potentially fatal lactic acidosis.
	www.aegis.com /factshts/network/simple/riba.html (1148 words)

	MedlinePlus Drug Information: Ribavirin (Systemic) (Site not responding. Last check: 2007-10-18)
		Ribavirin (rye-ba-VYE-rin) is used to treat severe virus pneumonia in infants and young children.
		Ribavirin taken by mouth (oral) treats a viral liver infection known as hepatitis C. It is used in combination with injectable interferon alfa-2b (in-ter-FEER-on AL-fa-2b) or with injectable peginterferon alfa-2b (peg-in-ter-FEER-on AL-fa-2b).
		Ribavirin for oral use should not be used while you are pregnant, if you plan on becoming pregnant, or by men whose female partners are pregnant or are planning to become pregnant.
	www.nlm.nih.gov /medlineplus/druginfo/uspdi/202509.html (1619 words)

	Ribavirin
		Ribavirin is an odorless, white powder used in hospitals as an anti-viral drug to treat respiratory syncytial virus (RSV) infection.
		Ribavirin absorbed into the body is cleared from plasma in a few hours, but may remain in red blood cells for several weeks.
		Environmental monitoring of health care workers who are exposed to ribavirin aerosol during oxygen tent or mask administration has shown that their exposures are often greater than levels that are recommended to protect against harm to the fetus.
	www.dhs.ca.gov /ohb/HESIS/riba.htm (1262 words)

	Hepatitis Central, Current Information On Hepatitis C for the medical professional and patient.
		Sequential versus concomitant administration of ribavirin and interferon alfa-n3 in patients with chronic hepatitis C not responding to interferon alone
		Ribavirin monotherapy in patients with chronic hepatitis C
		Interferon alpha with ribavirin for the treatment of chronic hepatitis C in non-responders or relapsers to interferon monotherapy
	hepatitis-central.com /hcv/ribavirin/toc.html (1025 words)

	Ribavirin (Site not responding. Last check: 2007-10-18)
		Intravenous ribavirin therapy in a neonate with disseminated adenovirus infection undergoing extracorporeal membrane oxygenation: pharmacokinetics and clearance by hemofiltration.
		Ribavirin therapy in bone marrow transplant recipients with viral respiratory tract infections.
		Precipitation of ribavirin causing obstruction of a ventilation tube.
	www.umdnj.edu /rspthweb/bibs/ribavirn.htm (1131 words)

	Ribavirin
		FDA approval is pending for Ribavirin and Interferon in combination for patients who have never undergone treatment.
		Pilot study of the combination of interferon alfa and ribavirin as therapy of recurrent hepatitis C after liver transplantation.
		Ribavirin enhances the efficacy but not the adverse effects of interferon in chronic hepatitis C. Meta-analysis of individual patient data from European centers.
	www.cpmc.org /advanced/liver/patients/topics/ribavirin.html (604 words)

	Ribavirin -- Facts, Info, and Encyclopedia article (Site not responding. Last check: 2007-10-18)
		The aerosol form is used to treat Respiratory Syncytial Virus (Click link for more info and facts about RSV) RSV diseases in children.
		The primary serious adverse effect of ribavirin is (Anemia resulting from destruction of erythrocytes) hemolytic anemia, which may worsen existing cardiac disease.
		Therefore, two (2) forms of (Limiting the number of children born) birth control should be used during treatment of either partner and continued for six (6) months after treatment.
	www.absoluteastronomy.com /encyclopedia/r/ri/ribavirin.htm (263 words)

	Disposition and Metabolic Profiles of [14C]Viramidine and [14C]Ribavirin in Rat and Monkey Red Blood Cells and Liver -- ...
		and ribavirin in the RBC and livers of rats and monkeys.
		Ribavirin uptake by human erythrocytes and the involvement of nitrobenzylthioinosine-sensitive (es)-nucleoside transporters.
		Ribavirin disposition in high-risk patients for acquired immunodeficiency syndrome.
	aac.asm.org /cgi/content/full/48/5/1872 (2332 words)

	Rebetol Online, Description, Chemistry, Ingredients - Ribavirin - RxList Monographs (Site not responding. Last check: 2007-10-18)
		• The primary toxicity of ribavirin is hemolytic anemia.
		In addition, ribavirin has a multiple-dose halflife of 12 days, and so it may persist in nonplasma compartments for as long as 6 months.
		Each milliliter of the solution contains 40 mg of ribavirin and the inactive ingredients sucrose, glycerin, sorbitol, propylene glycol, sodium citrate, citric acid, sodium, benzoate, natural and artificial flavor for bubble gum #15864, and water.
	www.rxlist.com /cgi/generic2/rebetol.htm (408 words)

	PWA Health Group: ribavirin
		Ribavirin was one of the first antiviral drugs ever discovered.
		Ribavirin increased the effect of ddI ten-fold in vitro.
		Long term use of ribavirin may lead to a build up of iron in the liver, which could be harmful.
	www.aidsinfonyc.org /pwahg/info/riba.html (1206 words)

	Ribavirin Pregnancy Registry, Charles River Laboratories Clinical Services, North Carolina
		The Ribavirin Pregnancy Registry is an important public health program established to assess any birth defects occurring in outcomes of pregnancy exposed to ribavirin in-utero.
		Exposures to ribavirin are direct exposures through the pregnant female taking ribavirin or indirect exposures through her male sexual partner who has taken ribavirin.
		The success of the Registry depends on the continued participation of health-care providers and their ribavirin exposed patients for registration and follow-up.The support and participation of patients and providers who have participated are greatly appreciated.
	www.ribavirinpregnancyregistry.com (165 words)

	Rebetol (ribavirin) / Copegus (ribavirin) - Complete Coverage
		Ribavirin Monotherapy Is Effective in Kidney Allograft Recipients with Chronic Hepatitis C
		Low-dose Ribavirin Monotherapy Is Well Tolerated in Transplant Recipients with Recurrent HCV Disease and Is Associated with a Significant Delay in Fibrosis Progression
		Weight-adjusted Higher Doses of Ribavirin Are Associated with Early Virologic Responses to Therapy for HCV
	www.hivandhepatitis.com /hep_c/hepc_news_ribavirin.html (735 words)

	Your Online Hepatitis C Encyclopedia (Site not responding. Last check: 2007-10-18)
		Hepatitis Central, Adding ribavirin to interferon -2b for chronic hepatitis C infection increased virological response and nausea
		Hepatitis Central, Interferon / Ribavirin Combination Therapy In Relapsers, Current Information On Hepatitis C and treatments for the medical professional and patient.
		Hepatitis Central, Sequential Versus Concomitant Administration of Ribavirin and Interferon Alfa-n3 in Patients With Chronic Hepatitis C Not Responding to Interferon Alone: Results of a Randomized, Controlled Trial
	hepatitis-central.com /sitemap.htm (8440 words)

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