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Topic: Ribofuranose


In the News (Fri 27 Nov 09)

  
 Process for the preparation of ribofuranose derivatives - Patent 6891036
It is therefore subject of the present invention a process for the preparation of ribofuranose derivatives of formula(I): ##STR7##
Further subject of this invention are the ribofuranose derivatives of formula (I): ##STR11##
The mixture is stirred for 1 hour then slowly cooled down to 20° C. It is filtered under vacuum and the panel is washed with 10.38 Kg of toluene and with 6 Kg of hexane.
www.freepatentsonline.com /6891036.html   (6497 words)

  
 [No title]   (Site not responding. Last check: 2007-10-18)
Toyocamycin and some analogues have shown potent antitumor activities; however, none of them could be used clinically primarily owing to their cytotoxicity to normal human cells.
In order to overcome the weakness of these nucleoside analogues, substitution of a variety of modified sugars for the ribofuranose was explored in our laboratories with expectation that certain sugar-modified toyocamycin analogues may be selectively cytotoxic to cancer cells.
In this article, we report synthesis and cytotoxicity of 4´-C- and 5´-C-substituted toyocamycins, which were prepared via the condensations of 4-C- and 5-C-substituted ribofuranose derivatives 11, 12, 13, 20, 21, and 26 with the silylated form of 4-amino-6-bromo-5-cyanopyrrolo[2,3-d]pyrimidine (27) and subsequent debromination and debenzoylation.
www.elsevier.com /cdweb/journals/09680896/articles/9/1/S096808960000221.abstract.en   (173 words)

  
 Cytidine : Deoxycytidine   (Site not responding. Last check: 2007-10-18)
Cytidine is a molecule (known as a nucleoside) that is formed when cytosine is attached to a ribose ring (also known as a ribofuranose) via a β-N1-glycosidic bond.
Cytidine is a molecule (known as a nucleoside) that is formed when cytosine is attached to a ribose ring (also known as a ribofuranose) via a β-N
If cytosine is attached to a deoxyribose ring, it is known as a deoxycytidine.
www.termsdefined.net /de/deoxycytidine.html   (207 words)

  
 Herbicidal ribofuranose derivatives - Patent 5683963   (Site not responding. Last check: 2007-10-18)
The present invention relates to herbicidal ribofuranose derivatives, particularly hydantocidin derivatives, compositions comprising said derivatives and methods of use.
This invention relates to herbicidal ribofuranose derivatives, and particularly to hydantocidin derivatives, compositions comprising said derivatives and methods of treating weeds utilizing the application of said derivatives to a locus where control is desired.
It has now been discovered that certain novel ribofuranose derivatives have good herbicidal and plant growth regulating activity when applied either pre or post emergence, but particularly post emergence and when used against annual and perennial grasses and broad leaf weeds.
freepatentsonline.com /5683963.html   (2695 words)

  
 Ribofuranose - Encyclopedia Glossary Meaning Explanation Ribofuranose   (Site not responding. Last check: 2007-10-18)
Here you will find more informations about Ribofuranose.
If you find this encyclopedia or its sister projects useful,
Ribofuranose is the chemical name for the 5-carbon sugar (pentose) commonly referred to as ribose.
www.encyclopedia-glossary.com /en/Ribofuranose.html   (63 words)

  
 Victor Brantl Patent Inventor Schliengen, DE
Schliengen, DE Use of ribofuranose derivatives against inflammatory bowel diseases
20050009768 - Use of ribofuranose derivatives against inflammatory bowel diseases
20050153907 - Use of ribofuranose derivatives against inflammatory bowel diseases
www.freshpatents.com /Victor-Brantl-Schliengen-invdirb.php   (112 words)

  
 Mutating Three Residues in the Bovine Rod Cyclic Nucleotide-Activated Channel Can Switch a Nucleotide from Inactive to ...
Rp- and Sp-8-CPT-cGMP are modified at the C8 position on the purine.
The ribofuranose binding pocket is formed, in part, by E523, R538, and T539.
contacting the ribofuranose are conserved in all members of the
www.biophysj.org /cgi/content/full/78/5/2321   (5835 words)

  
 [No title]   (Site not responding. Last check: 2007-10-18)
A method of treatment [or prophylaxis] of an inflammatory bowel disease in a subject in need of said treatment [or prophylaxis], said method comprising:
carbon of the ribofuranose moiety is [D or] L; and
administering said one or more ribofuranose derivatives to said subject in an amount effective to treat [or revent] said inflammatory bowel disease.
www.uspto.gov /web/patents/patog/week33/OG/html/1297-3/US06930093-20050816.html   (128 words)

  
 Nucleic Acids
Nucleic acids are divided into classes on the basis of the sugar used to form the nucleotides.
Deoxyribonucleic acid (DNA) contains a modified ribofuranose in which the -OH group on the second carbon atom has been removed, as shown in the fiugre below.
The amines that form nucleic acids fall into two categories: purines and pyrimidines.
chemed.chem.purdue.edu /genchem/topicreview/bp/1biochem/nucleic8.html   (610 words)

  
 NMR Application Probes a Novel and Ubiquitous Family of Enzymes That Alter Monosaccharide Configuration -- Ryu et al. ...
It was observed that the anomeric exchange of only ribofuranose,
It is tempting to speculate that the evolutionary choice of
ribofuranose as a component of nucleic acids might have resulted
www.jbc.org /cgi/content/full/279/24/25544   (2463 words)

  
 U.S. Pregrant 20040175808 - Process to ribofuranose sugar derivatives as intermediates to branched-chain nucleosides   (Site not responding. Last check: 2007-10-18)
U.S. Pregrant 20040175808 - Process to ribofuranose sugar derivatives as intermediates to branched-chain nucleosides
Process to ribofuranose sugar derivatives as intermediates to branched-chain nucleosides
A novel process is provided for the preparation of ribofuranose sugar derivatives which are useful in the synthesis of branched-chain ribonucleoside inhibitors of HCV polymerase for the treatment of HCV infection.
cxp.paterra.com /uspregrant20040175808.html   (176 words)

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