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Topic: Rickettsia prowazekii

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Epidemic typhus

Typhus (disease)

Typhus

Rickettsia

Endemic typhus

Bergen Belsen

Robusta

Neisseria gonorrheae

Entamoeba histolytica

Incubation period

Pediculus humanus

Rakhine

Bolitaenidae

Yersinia pestis

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	Rickettsia - MicrobeWiki
		Rickettsia conorii causes Mediterranean spotted fever in humans and is contracted by contact with infected brown dog ticks.
		In addition to this, the genome of Rickettsia prowazekii is similar to mitochondrial genomes; phylogenetically, R.
		Rickettsia bacteria are obligate intracellular pathogens that are dependent on entry, growth, and replication within the cytoplasm of a eukaryotic host cell.
	microbewiki.kenyon.edu /index.php/Rickettsia (774 words)

	Epidemic typhus - Wikipedia, the free encyclopedia
		Epidemic typhus, also called Jail Fever, is a form of typhus caused by the bacillus Rickettsia prowazekii, carried by the human body louse Pediculus humanus.
		prowazekii grows in the louse's gut and is excreted in the feces.
		Henrique da Rocha Lima in 1916 then proved that the bacteria Rickettsia prowazekii was the agent responsible for typhus; he named bacteria after H.
	en.wikipedia.org /wiki/Epidemic_typhus (892 words)

	Pathogenic mechanisms of diseases caused by Rickettsia
		Rickettsiae attach to a protein-dependent receptor on the host cell membrane and induce focal host cell cytoskeletal rearrangements at the site of attachment, resulting in their entry into the host cell even in nonprofessional phagocytes by a mechanism requiring rickettsial metabolic activity (Walker, et al., 2003).
		Rickettsia attach to a protein dependent receptor on the host cell membrane and induce focal host cell cytoskeletal rearrangements at the site of attachment, resulting in their entry into the host cell even in nonprofessional phagocytes by a mechanism requiring rickettsial metabolic activity (Walker et al., 2003).
		Rickettsia attach to a protein dependent receptor on the host cell membrane and induce focal host cell cytoskeletal rearrangements at the site of attachment, resulting in their entry into the host cell even in nonprofessional phagocytes by a mechanism requiring rickettsial metabolic activity (Walker et al.,2003).
	pathport.vbi.vt.edu /minet/xmlfiles/Rickettsia_prowazekii.xml (1068 words)

	nature genome gateway - papers - Rickettsia prowazekii (Site not responding. Last check: 2007-10-23)
		prowazekii is of interest as being possibly the closest extant relative of the ancestor to mitochondria.
		As an intracellular parasite in eukaryotic cells, the Rickettsia genome, like that of mitochondria, shows the effects of the evolutionary forces reducing its complexity.
		The genome sequence of Rickettsia prowazekii and the origin of mitochondria
	www.nature.com /genomics/papers/r_prowazekii.html (123 words)

	STEFAN KRYNSKI, EUGENIUSZ BECLA, MARIAN MACHEL - WEIGL'S METHOD OF INTRARECTAL INOCULATION OF LICE IN RODUCTION OF ... (Site not responding. Last check: 2007-10-23)
		Rickettsiae released into the intestinal lumen start to attack healthy epithelial cells and the second period of louse infection is thus initiated.
		The supernatant containing rickettsiae is withdrawn and the residue is washed twice The rickettsial suspension is then subjected to centrifugation during 1 h at the speed of 5000-6000 r.p.m.
		Rickettsia rocha-limae in spite of abundant multiplication in epithelium cells of louse stomach does not cause its reddening and death.
	www.lwow.home.pl /Weigl/krynski/teoria.html (8475 words)

	Gene and protein applicable to the preparation of vaccines for rickettsia prowazekii and rickettsia typhi and the ...
		prowazekii is the etiological agent of epidemic typhus and is well established in its primary host, man. The human body louse is the primary vector.
		The etiologic agent of epidemic typhus, Rickettsia prowazekii, is an obligate intracellular bacterium.
		The invention is also accomplished by the deduced amino acid sequence of the S-layer protein of R. prowazekii derived from the DNA sequence of the encoding gene homologs, and variants together with a suitable vector.
	freepatentsonline.com /5783441.html (5079 words)

	Rickettsia, Chlamydia, Mycoplasma
		The rickettsia have many of the metabolic capabilities of bacteria, but require an exogenous supply of cofactors to express these capabilities.
		Under poor nutritional conditions, the rickettsia cease dividing and grow into long filamentous forms, which subsequently undergo rapid and multiple division into the typical short rod forms when fresh nutrient is added.
		In their arthropod vectors, the rickettsia multiply in the epithelium of the intestinal tract; they are excreted in the feces, but occasionally gain access to the arthropods salivary glands.
	www.kcom.edu /faculty/chamberlain/Website/Lects/RICKETT.HTM (2941 words)

	eMedicine - Typhus : Article by Jason F Okulicz, MD
		Rickettsia prowazekii, which is the etiologic agent of typhus, lives in the alimentary tract of the louse.
		Typhus is an acute febrile illness caused by rickettsial organisms.
		Saah AJ: Rickettsia prowazekii (epidemic or louse-borne typhus).
	www.emedicine.com /med/topic2332.htm (3185 words)

	Detection of Rickettsia prowazekii in Body Lice and Their Feces by Using Monoclonal Antibodies -- Fang et al. 40 (9): ...
		Rickettsia prowazekii is the causative agent of epidemic typhus,
		prowazekii antigen (SDS-PAGE); lanes 3, 5, and 7, MAb P11A12; lanes 4, 6, and 8, MAb P9G1; lane 9, polyclonal antisera against native antigen (lanes 3, 4, and 9), heated antigen (lanes 5 and 6), and proteinase K-digested antigen (lanes 7 and 8).
		Detection and characterization of mouse monoclonal antibodies to epidemic typhus rickettsiae.
	jcm.asm.org /cgi/content/full/40/9/3358 (2775 words)

	In Vitro Activities of Telithromycin (HMR 3647) against Rickettsia rickettsii, Rickettsia conorii, Rickettsia africae, ... (Site not responding. Last check: 2007-10-23)
		In Vitro Activities of Telithromycin (HMR 3647) against Rickettsia rickettsii, Rickettsia conorii, Rickettsia africae, Rickettsia typhi, Rickettsia prowazekii, Coxiella burnetii, Bartonella henselae, Bartonella quintana, Bartonella bacilliformis, and Ehrlichia chaffeensis -- Rolain et al.
		In vitro antibiotic susceptibility of Rickettsia rickettsii and Rickettsia conorii: plaque assay and microplaque colorimetric assay.
		In vitro susceptibilities of 27 rickettsiae to 13 antimicrobials.
	aac.asm.org /cgi/content/full/44/5/1391 (1363 words)

	Characterization of the gene coding for the Rickettsia prowazekii DNA primase analogue. (Site not responding. Last check: 2007-10-23)
		Characterization of the gene coding for the Rickettsia prowazekii DNA primase analogue.The gene (dnaG) coding for DNA primase in the obligate intracellular parasitic bacterium, Rickettsia prowazekii, has been isolated and characterized.
		The R. prowazekii dnaG gene failed to complement an E. coli dnaG temperature sensitive mutation perhaps due to poor expression of the gene or inability to function properly in E. coli.
		Based on aa sequence comparisons of DNA primase from R. prowazekii, Escherichia coli, Salmonella typhimurium and Bacillus subtilis, we propose that R. prowazekii dnaG begins 69 bp into the ORF and encodes 593 aa with a calculated M(r) of 68,683.
	www.pdg.cnb.uam.es /UniPub/iHOP/gp/81323.html (241 words)

	[No title] (Site not responding. Last check: 2007-10-23)
		Rickettsia prowazekii is a member of alpha proteobacteria and the etiologic agent of epidemic typhus.
		The sequencing and analysis of the entire R. prowazekii genome have provided evidence for an exclusive obligate intracellular parasite with massive genomic reduction and a general genomic rearrangement in addition to an unusually high fraction (24) of non-coding regions.
		A comparative analysis between the complete genomes of the R. prowazekii and the Chlamydia trachomatis, a distantly related obilgate intracellular parasite, uncovered a total of 325 genes with significant homology between the two genomes.
	dbase.irandoc.ac.ir /00234/00234081.htm (411 words)

	News - Potential role of head lice as vectors of Rickettsia prowazekii
		LBET, which is caused by infection with Rickettsia prowazekii, is one of the most devastating illnesses to a.ict human kind.
		By destroying the rickettsiae in the host, the bacteria could not be transmitted by any head or body lice that survived delousing.
		Thus, the role of head lice in transmission of R. prowazekii during epidemics of LBET cannot be determined since both head lice and body lice were eliminated.
	www.headlice.org /news/2003/robinsonetal.htm (2123 words)

	Expression of the Rickettsia prowazekii citrate synthase gene in Escherichia coli. (Site not responding. Last check: 2007-10-23)
		Expression of the Rickettsia prowazekii citrate synthase gene in Escherichia coli.
		Expression of the Rickettsia prowazekii citrate synthase gene in Escherichia coli.Analysis of citrate synthase activity in crude extracts revealed that the enzyme expressed in E. coli retains the regulatory control mechanisms characteristic of the rickettsial enzyme.
		Recombinant DNA techniques were used to isolate the Rickettsia prowazekii citrate synthase gene on the plasmid vector pBR322 by functional complementation of a gltA mutation of Escherichia coli K-12.
	www.pdg.cnb.uam.es /UniPub/iHOP/gp/4470539.html (76 words)

	Rickettsia (Site not responding. Last check: 2007-10-23)
		The Rickettsia are Gram-negative, obligate intracellular bacteria that infect mammals and arthropods.
		Rickettsia replicate in the cytoplasm and nucleus of their host cell; Coxiella replicate only in the phagolysosome.
		Typhus, spotted fever and trench fever are transmitted via arthropod vectors; Q fever is acquired via inhalation or ingestion of contaminated milk or food.
	www.cehs.siu.edu /fix/medmicro/ricke.htm (461 words)

	Rickettsia_prowazekii (Site not responding. Last check: 2007-10-23)
		Rickettsia prowazekii is an obligate intracellular Gram-negative parasite.
		As an intracellular parasite in eukaryotic cells, the Rickettsia genome, like that of mitochondria, shows the effects of the evolutionary forces reducing its complexity and insight into adaptations of the obligate intracellular lifestyle.
		The bacterium is named after two typhus researchers who died of the disease in the early 20th century, H.T. Ricketts and S.J.M. Prowazek.
	www.ebi.ac.uk /2can/genomes/bacteria/Rickettsia_prowazekii (145 words)

	NTI: Typhus (Rickettsia prowazekii)
		Caused by a rickettsial pathogen (Rickettsia prowazekii), the classic, epidemic form of typhus is transmitted by the human body louse Pediculus, and the pathogen is also carried along by infected rats and other rodents such as the flying squirrel.
		No longer considered a significant BW threat in the modern era, a number of biological warfare (BW) programs have investigated typhus as a weapon, including the United States (World War II) and the former Soviet Union.
		In the classic form of illness, R. prowazekii organisms multiply at the focus of the insect bite, and being parasites these bacteria grow within the cellular tissue.
	www.nti.org /e_research/profiles/NK/Biological/236.html (346 words)

	Transposon Mutagenesis of the Obligate Intracellular Pathogen Rickettsia prowazekii -- Qin et al. 70 (5): 2816 -- ...
		Rickettsiae were purified from the yolk sacs of
		Gene synthesis, bacterial expression and purification of the Rickettsia prowazekii ATP/ADP translocase.
		Transformation of Rickettsia prowazekii to erythromycin resistance encoded by the Escherichia coli ereB gene.
	aem.asm.org /cgi/content/full/70/5/2816 (3527 words)

	Rickettsia and Associated Pathology (Site not responding. Last check: 2007-10-23)
		Vaccines exist for several of the pathogenic rickettsia and are recommended for at risk populations.
		This scratching spreads rickettsia shed in the feces into the bite and blood stream of the person.
		prowazekii, the rickettsia is shed in the feces of the insect vector and scratching of the bite site by the person spreads the infected feces into the bite.
	www.ivytech.net /twmurphy/text_pg/ricket.htm (861 words)

	Rickettsia prowazekii
		The Rickettsia prowazekii Madrid E genome page is provided by TIGR (The Institute of Genome Research) as part of their Comprehensive Microbial Resource, a tool that allows the researcher to access all of the bacterial genome sequences completed to date.
		Gene pairs for Rickettsia prowazekii Madrid E is provided by The Institute of Genome Research (TIGR) as part of their "Predicting operons in microbial genomes" resource.
		This resource is based on a method developed at TIGR to detect and analyse conserved gene pairs; the method revealed that a large number of gene clusters are conserved between microbial genomes.
	bioresearch.ac.uk /browse/mesh/D012283.html (277 words)

	NTI: Typhus (Rickettsia prowazekii)
		Caused by a rickettsial pathogen (Rickettsia prowazekii), the classic, epidemic form of typhus is transmitted by the human body louse Pediculus, and the pathogen is also carried along by infected rats and other rodents such as the flying squirrel.
		No longer considered a significant BW threat in the modern era, a number of biological warfare (BW) programs have investigated typhus as a weapon, including the United States (World War II) and the former Soviet Union.
		In the classic form of illness, R. prowazekii organisms multiply at the focus of the insect bite, and being parasites these bacteria grow within the cellular tissue.
	www.thenti.com /e_research/profiles/NK/Biological/236.html (346 words)

	The Rickettsia prowazekii Invasion Gene Homolog (invA) Encodes a Nudix Hydrolase Active on Adenosine ...
		The Rickettsia prowazekii Invasion Gene Homolog (invA) Encodes a Nudix Hydrolase Active on Adenosine (5')-pentaphospho-(5')-adenosine -- Gaywee et al.
		The Rickettsia prowazekii Invasion Gene Homolog (invA) Encodes a Nudix Hydrolase Active on Adenosine (5')-pentaphospho-(5')-adenosine
		Rickettsia prowazekii is the etiologic agent of epidemic typhus
	www.mcponline.org /cgi/content/full/1/3/179 (3264 words)

	ExactAntigen rickettsia prowazekii monoclonal antibodies (Site not responding. Last check: 2007-10-23)
		(2004) Proteome analysis of Madrid E strain of Rickettsia prowazekii.
		(2004) Cysteine-scanning mutagenesis and thiol modification of the Rickettsia prowazekii ATP/ADP translocase: evidence that transmembrane regions I and II, but not III, are structural components of the aqueous translocation channel.
		(2003) Genomic studies of Rickettsia prowazekii virulent and avirulent strains.
	www.exactantigen.com /species/others/r/rickettsia-prowazekii-antibodies.html (230 words)

	Rickettsia diagnosis, detection, research and treatments (Site not responding. Last check: 2007-10-23)
		In South Africa, in addition to practicing as a surgeon, she also assisted her husband in his general practice.
		For the last years, she has focused on the subject of Rickettsia and her approach has naturally been that of a clinician.
		To understand why she took the Rickettsial approach her background needs to be explained.
	www.cfsresearch.org /rickettsia (254 words)

	Characterization of the Gene Encoding the Protective Paracrystalline- Surface-Layer Protein of Rickettsia prowazekii: ...
		Characterization of the Gene Encoding the Protective Paracrystalline- Surface-Layer Protein of Rickettsia prowazekii: Presence of a Truncated Identical Homolog in Rickettsia typhi -- Carl et al.
		A complementary 8.7-kilobase EcoRI fragment of Rickettsia typhi DNA was cloned.
		J. TEMENAK, and A. Real-Time PCR Duplex Assay for Rickettsia prowazekii and Borrelia recurrentis
	www.pnas.org /cgi/content/abstract/87/21/8237 (438 words)

	Typhus
		Several different illnesses called "typhus" exist, all of them caused by one of the bacteria in the family Rickettsiae.
		The specific type of Rickettsia that causes the disease also varies, as does the specific insect that can pass the bacteria along.
		Epidemic typhus is caused by Rickettsia prowazekii, which is carried by body lice.
	www.healthatoz.com /healthatoz/Atoz/ency/typhus.jsp (957 words)

	Rickettsia prowazekii, Rickettsia canadensis (Formerly R. canada) - Material Safety Data Sheets (MSDS)
		Rickettsia prowazekii, Rickettsia canadensis (Formerly R. canada) - Material Safety Data Sheets (MSDS)
		SURVIVAL OUTSIDE HOST: Rickettsia may remain viable in louse fecal material and the dead louse for weeks
		Newly discovered hazards are frequent and this information may not be completely up to date.
	www.phac-aspc.gc.ca /msds-ftss/msds128e.html (508 words)

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