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	Roderick MacKinnon - Wikipedia, the free encyclopedia
		Roderick MacKinnon (born 19 February 1956 in Burlington, Massachusetts) is a professor of Molecular Neurobiology and Biophysics at Rockefeller University who in 2003 was awarded the Nobel Prize in Chemistry for his work on the structure and operation of ion channels.
		A professor of Molecular Neurobiology and Biophysics at the Rockefeller University and an investigator with Howard Hughes Medical Institute, MacKinnon was elected to the U.S. National Academy of Sciences in 2000.
		MacKinnon has received numerous awards for his research, including the 2000 Rosenstiel Award and the 2001 Gairdner Foundation International Award.
	en.wikipedia.org /wiki/Roderick_MacKinnon (398 words)

	Columbia's Horwitz Prize Awarded to Nobel Laureate Roderick Mackinnon
		Roderick MacKinnon, a 2003 Nobel Laureate (in chemistry) and professor of molecular neurobiology and biophysics at Rockefeller University, is the recipient of this year's Louisa Gross Horwitz Prize.
		MacKinnon was honored for his studies of ion channels, work that sheds light on how salts (ions) are transported in and out of cells.
		MacKinnon's prize-winning research focuses on the biophysical, structural and functional aspects of ion channels, which control the electrical potential of cell membranes in the natural world.
	www.columbia.edu /cu/news/04/03/horowitz_prize.html (217 words)

	Roderick MacKinnon - Biophysicist and the Ion Channel
		Roderick MacKinnon was born in 1956 in Burlington, Massachusetts, a town northwest of metropolitan Boston.
		MacKinnon was encouraged to go his own way, a trait that has led to a series of turns in his career path that proved to be the right turns.
		In 1998, MacKinnon published the first three-dimensional structure of a protein, the potassium ion channel; his achievement was hailed as a significant breakthrough.
	www.suite101.com /article.cfm/biographies_scientists/109849 (641 words)

	C&EN: AHA! MOMENTS - RODERICK MACKINNON
		oderick MacKinnon, a biophysicist and self-taught X-ray crystallographer at Rockefeller University, was awarded the 2003 Nobel Prize in Chemistry for elucidating the chemical mechanisms of potassium ion channels.
		MacKinnon and others spent more than a decade trying to determine the chemical basis of potassium channels' exquisite selectivity by carefully mutating individual amino acids in the protein.
		In MacKinnon's high-resolution structures, a queue of potassium ions (green; their electron density is shown as blue mesh) can be seen in ion pathway of the potassium channel protein KcsA.
	pubs.acs.org /cen/aha!/8144mackinnon.html (404 words)

	HHMI News: Visualizing a Potassium Channel
		Roderick MacKinnon at The Rockefeller University unveils the crystal structure that shows the potassium channel's surprising architecture.
		MacKinnon's laboratory and others around the world understood that a complete picture of a potassium channel was badly needed.
		In collaboration with Rockefeller colleagues Steven Cohen and Brian Chait, MacKinnon's team showed that the scorpion toxin binds to a slightly modified bacterial potassium channel, confirming that the two channels are structurally similar.
	www.hhmi.org /news/mackinnon.html (759 words)

	MacKinnon profile (Site not responding. Last check: 2007-10-21)
		Last year, MacKinnon was praised by colleagues when he solved the molecular structure of the potassium ion channel--an accomplishment hailed by Science magazine as one of its "Breakthroughs of the Year," and described in a commentary by a fellow scientist as "a remarkable achievement."
		MacKinnon is acclaimed in his field for his penetrating ability to make sense of technical information and bring it to a clear resolution in his mind.
		MacKinnon also is very grateful to Miller for taking him under his wing and helping him develop a fuller understanding in physics and chemistry.
	www.rockefeller.edu /pubinfo/profilemackinnon.html (931 words)

	MacKinnon lecture coverage (Site not responding. Last check: 2007-10-21)
		MacKinnon, who spoke on "Potassium Channels" for the 2004 James B. Sumner Lecture Oct. 29 in Cornell's Call Alumni Auditorium, brought an apt audience of students and faculty-researchers up to date on his latest ideas about what regulates the flow of potassium ions through the channels' pores.
		Since his 1998 landmark work, when MacKinnon determined the spatial structure of the potassium channel and provided a partial explanation of how ion channels can be opened and closed by different cellular signals, he has focused much of his research on the finer points of voltage-dependent ion channel gating.
		At Rockefeller University, MacKinnon is a professor in the laboratory of Molecular Neurobiology and Biophysics and a Howard Hughes Medical Investigator.
	www.news.cornell.edu /chronicle/04/11.4.04/MacKinnon_cover.html (470 words)

	Epochtimes English Edition- (Site not responding. Last check: 2007-10-21)
		Biochemists Peter Agre, 54, and Roderick MacKinnon, 47, were lauded for work that will help the search to conquer illnesses that strike the kidneys, heart, muscles and nervous system in particular.
		But Agre and MacKinnon are young and their research is recent, both of which reflect the fast-growing importance of molecular biology.
		MacKinnon "surprised the whole research community", the jury said, when he in 1998 was able to determine the spatial structure of a potassium channel.
	english.epochtimes.com /news/3-10-8/9449.html (722 words)

	Roderick MacKinnon wins 2003 Nobel Prize in Chemistry
		Roderick MacKinnon, a Howard Hughes Medical Institute (HHMI) investigator at The Rockefeller University, is one of two scientists who were awarded the 2003 Nobel Prize in Chemistry for discoveries concerning channels in cell membranes.
		In 1998, much to the surprise of colleagues, MacKinnon and his colleagues determined the three-dimensional structure of a pore that allows cells to control their intake of potassium ions.
		After bombarding the crystals with x-rays, MacKinnon and his colleagues were able to deduce that the potassium channel is made up of four identical subunits assembled in the shape of an inverted teepee.
	www.eurekalert.org /pub_releases/2003-10/hhmi-rmw100803.php (968 words)

	Roderick MacKinnon - Wikipedia, the free encyclopedia (Site not responding. Last check: 2007-10-21)
		Roderick MacKinnon (born 1956 in Burlington, Massachusetts) An award-winning scientist, in the biophsicist field, he has produced groundbreaking research detailing the way the body's electrical systems function, by unlocking the secrets of the body's ion channel proteins.
		In 2003 he was awarded the Nobel Prize in Chemistry (shared with Peter Agre) for his work on structural and mechanistic studies of ion channels.
		But in 1998, MacKinnon unlocked the channel's secrets, resulting in one of the biggest scientific breakthroughs of the year.
	wikipedia.lotsofinformation.com /wiki/index.php/Roderick_MacKinnon (360 words)

	Cornell News: Former Cornellians win Nobels
		Roderick MacKinnon, a visiting researcher at Cornell High Energy Synchrotron Source (CHESS), was a co-recipient of the Nobel Prize in Chemistry.
		MacKinnon, a professor at The Rockefeller University and an investigator at the Howard Hughes Medical Institute, shared the chemistry Nobel with Peter Agre of Johns Hopkins University School of Medicine for work explaining how a class of membrane proteins, called channels, help to regulate cells.
		MacKinnon, a biophysicist and self-taught X-ray crystallographer, did much of the work leading to the prize primarily at CHESS, an X-ray facility supported by the National Science Foundation and the National Institutes of Health, and the National Synchrotron Light Source at the U.S. Department of Energy's Brookhaven National Laboratory.
	www.news.cornell.edu /releases/Oct03/CHESS.MacKinnon.deb.html (863 words)

	Roderick MacKinnon (Site not responding. Last check: 2007-10-21)
		Lalonde and Roderick Family History Ancestral database with roots in Canada and New York, compiled by Lucinda G (Cindy) LaLonde Roderick and Thad P Roderick, Snr.
		MacKinnon Descendants of Donald Mackinnon and Mary McLeod from the Isle of Skye, SCT.
		Roderick M. Chisholm At Brown University, where Roderick Chisholm, a dominant figure in American 20th century epistemology, was a professor.
	www.serebella.com /encyclopedia/article-Roderick_MacKinnon.html (271 words)

	Brandeis University - News (Site not responding. Last check: 2007-10-21)
		Such channels are the fundamental molecular hardware of cellular electrical activity; their importance is underscored by the fact that of the 3,000 known drugs targeted at human diseases and disorders, close to half act by binding to ion channels.
		MacKinnon's early work employed close biophysical analysis of ion channel behavior to establish the overall molecular construction of the family of voltage-gated ion channels.
		MacKinnon's contributions to science have previously been recognized with a Pew Scholarship and a McKnight Scholars Award in 1992, the Biophysical Society's Young Investigator Award in 1995, the McKnight Investigator Award in 1997, and the Newcomb Cleveland Prize of the American Association for the Advancement of Science in 1998.
	www.brandeis.edu /news/rosenstiel.html (540 words)

	Nobel Prize winner in Chemistry used ESRF biocrystallography facilities - ESRF (Site not responding. Last check: 2007-10-21)
		Roderick MacKinnon was a visiting scientist at ESRF several times in the year 2000 and worked on potassium and chloride channels.
		Professor Mackinnon is currently the head of the Laboratory of Molecular Neurobiology and Biophysics at the Rockefeller University in New York, USA.
		This year, the Nobel Prize in Chemistry 2003 was awarded “for the discoveries concerning channels in cell membranes”, with half of the prize to Roderick MacKinnon and the other half to Peter Agre for the discovery of water channels.
	www.esrf.fr /NewsAndEvents/News/MacKinnon/printview (250 words)

	Roderick on Encyclopedia.com (Site not responding. Last check: 2007-10-21)
		Roderick was probably killed in the battle, but according to some, he continued to resist the Muslim conquest of Spain until he was slain in 713.
		Roderick MacKinnon Roderick MacKinnon, 47 ans, professeur de neurobiologie moléculaire et de biophysique à l'Institut médi.
		Roderick John Scott (2e en haut) journaliste britannique tué en Tchétchénie en septembre Dix-neuf journalistes ont été tué.
	www.encyclopedia.com /html/R/Roderick.asp (827 words)

	The Lasker Foundation \| Former Award Winners, Basic Medical Research
		MacKinnon is professor and head of the Laboratory of Molecular Neurobiology and Biophysics, Howard Hughes Medical Institute, Rockefeller University, New York City.
		MacKinnon recounts the amusing "white board" story from his days at Harvard and reflects on the overall state of ion channel research.
		MacKinnon and Miller discuss what they see as a psychological wall that is crumbling with the emergence of structures from the works of MacKinnon and others.
	www.laskerfoundation.org /awards/library/1999b_int_mr1.shtml (326 words)

	RODERICK MACKINNON FACTS AND INFORMATION (Site not responding. Last check: 2007-10-21)
		Roderick MacKinnon (born 19_February 1956 in Burlington,_Massachusetts) is a professor of Molecular Neurobiology and Biophysics at Rockefeller_University who in 2003 was awarded the Nobel_Prize_in_Chemistry for his work on the structure and operation of ion_channels.
		A professor of Molecular Neurobiology and Biophysics at the Rockefeller_University and an investigator with Howard_Hughes_Medical_Institute, MacKinnon was elected to the U.S. National Academy of Sciences in 2000.
		MacKinnon has received numerous awards for his research, including the 2000 Rosenstiel_Award and the 2001 Gairdner Foundation International Award.
	www.brolgas.com /Roderick_MacKinnon (348 words)

	Encyclopedia: Roderick MacKinnon
		X-ray crystallography is a technique in crystallography in which the pattern produced by the diffraction of X-rays through the closely spaced lattice of atoms in a crystal is recorded and then analyzed to reveal the nature of that lattice.
		A toxin, in a scientific context, is a biologically produced substance that causes injury to the health of a living thing on contact or absorption, typically by interacting with biological macromolecules such as enzymes and receptors.
		Jump to: navigation, search In 1971, the Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Resarch was established as an expression of the conviction that educational institutions have an important role to play in the encouragement and development of basic science as it applies to medicine.
	www.nationmaster.com /encyclopedia/Roderick-MacKinnon (1132 words)

	Nobelist To Give Stetten Lecture On Ion Channels, Oct. 27 - October 12, 2004 NIH Record - National Institutes of Health ...
		MacKinnon first became interested in ion channels when he was completing a residency in internal medicine at Beth Israel Hospital in Boston.
		MacKinnon was attracted to the quantitative rigor of studying ion channels and in particular to two issues: channel discrimination and gating.
		MacKinnon received a B.A. in biochemistry in 1978 from Brandeis University and an M.D. in 1982 from Tufts University.
	www.nih.gov /nihrecord/10_12_2004/story04.htm (666 words)

	MacKinnon lab's newest picture tells action potential story
		MacKinnon and colleagues have eclipsed their own already formidable contributions to the field of ion channel research -- contributions that widen a foot trail into an avenue for an entire new area of medical study on ion channel diseases.
		A colleague of MacKinnon, Rockefeller Professor David Gadsby, who heads a separate lab and also studies ion channels and their functioning, cites MacKinnon's attentiveness to conserved parts as one of the keys to his canny leadership.
		MacKinnon insists the secret to his success is the team of hardworking, exemplary researchers who seek him out.
	www.eurekalert.org /pub_releases/2003-04/ru-mln043003.php (1404 words)

	2 scientists share Nobel Prize for chemistry
		Peter Agre and Roderick MacKinnon have won the Nobel Prize in Chemistry for 2003 for discoveries concerning channels in cell membranes.
		Agre, from Johns Hopkins University School of Medicine, Baltimore, USA, is credited with the discovery of water channels and Roderick MacKinnon, from the Howard Hughes Medical Institute, The Rockefeller University, New York, USA, with the structural and mechanistic studies of ion channels.
		Roderick MacKinnon surprised the whole research community when in 1998 he was able to determine the spatial structure of a potassium channel.
	ushome.rediff.com /news/2003/oct/08nobel.htm (427 words)

	Boston.com / News / Boston Globe / Health / Science / Nobel winner followed his heart into research
		But in just two years, MacKinnon and his small X-ray crystallography lab were able to see into the inner workings of a cell in a way that had never been done before.
		MacKinnon got a grant from the American Heart Association to study how the heart relaxes and contracts, which got him interested in potassium channels -- and on the path toward the Nobel.
		MacKinnon's achievement opens up new directions in basic research, and it eventually may help fix problems with electrical signals in the brain.
	www.boston.com /news/globe/health_science/articles/2003/10/21/nobel_winner_followed_his_heart_into_research?mode=PF (830 words)

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