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Topic: Rofecoxib

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In the News (Fri 22 Jun 18)

  Rheumatoid Arthritis: Encyclopedia of Medicine
Unlike the NSAIDs, the COX-2 inhibitors do not carry a high risk of gastrointestinal ulcers and bleeding, because they do not inhibit COX-1, which is the enzyme that protects the stomach lining.
Celecoxib has been approved by the FDA for the treatment of RA and osteoarthritis, and is taken once or twice daily by mouth.
Rofecoxib is approved for RA and osteoarthritis, and for acute pain caused by primary dysmenorrhea and surgery.
health.enotes.com /medicine-encyclopedia/rheumatoid-arthritis   (2348 words)

 MedlinePlus Drug Information: Rofecoxib
Merck & Co., Inc. announced a voluntary withdrawal of rofecoxib (Vioxx) from the U.S. and worldwide market due to safety concerns of an increased risk of cardiovascular events (including heart attack and stroke) in patients on rofecoxib.
Rofecoxib is used to relieve the pain, tenderness, inflammation (swelling), and stiffness caused by arthritis and to treat painful menstrual periods and pain from other causes.
Rofecoxib is in a class of nonsteroidal anti-inflammatory medications (NSAIDs) called COX-2 inhibitors.
www.nlm.nih.gov /medlineplus/druginfo/medmaster/a699046.html   (752 words)

 Vioxx Drug Description - Rofecoxib - HealthScout
On Sept. 30, 2004 Merck & Co., Inc. announced a voluntary worldwide withdrawal of VIOXX® (rofecoxib).
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www.healthscout.com /rxdetail/1/73/1/main.html   (61 words)

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