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Topic: Selective serotonin reuptake inhibitor

Related Topics

SNRI

Antidepressant

Serotonin

Human serotonin transporter gene

Seratonin

Escitalopram oxalate

Desipramine

Citalopram

Antidepressant

Adverse effect (medicine)

Paroxetine

Tricyclic antidepressant

Venlafaxine

Fluoxetine

Monoamine oxidase inhibitor

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	Selective serotonin reuptake inhibitor - Wikipedia, the free encyclopedia
		Selective serotonin reuptake inhibitors (SSRIs) are a class of antidepressants used in the treatment of depression, anxiety disorders and some personality disorders.
		The resulting serotonin deficiency persists for some time, as the transporter inhibition occurs downstream to the cause of the deficiency, and is therefore not able to counterbalance it.
		Serotonin cannot be administered directly because when ingested orally, it will not cross the blood-brain barrier, and therefore won't have an effect on brain functions.
	en.wikipedia.org /wiki/Selective_serotonin_reuptake_inhibitor (2444 words)

	Selective serotonin reuptake inhibitors Encyclopedia of Medicine - Find Articles
		Selective serotonin reuptake inhibitors are medicines that relieve symptoms of depression.
		Selective serotonin reuptake inhibitors are used to treat serious, continuing depression that interferes with a person's ability to function.
		Selective serotonin reuptake inhibitors also are used to treat panic disorder, obsessive compulsive disorder (OCD), and have shown promise for treating a variety of other conditions, such as premenstrual syndrome, eating disorders, obesity, self-mutilation, and migraine headache.
	www.findarticles.com /p/articles/mi_g2601/is_0012/ai_2601001233 (1038 words)

	Anxiety Zone - Selective serotonin reuptake inhibitor
		Selective serotonin reuptake inhibitors (SSRIs) are a class of antidepressants.
		As a result, the serotonin stays in the synaptic gap longer than it normally would, and has the chance to be recognized again (and again) by the receptors of the recipient cell, which can finally be stimulated that way.
		The mode of action of these antidepressant drugs on their direct target, the serotonin transport protein, and possible regulatory mechanisms with respect to long-term alleviation of depression, although having been investigated both neurobiologically and clinically over the last years, are not yet understood.
	www.anxietyzone.com /glossary/selective_serotonin_reuptake_inhibitor.html (1360 words)

	Selective serotonin reuptake inhibitor
		Selective serotonin reuptake inhibitors (SSRIs) are a class of antidepressants for treating depression, anxiety disorders and some personality disorders.
		Pharmacologically, this delay is due to a side-effect of the initially high levels of serotonin within the synaptic gap: high serotonin levels will not only activate the postsynaptic receptors, but also flood the autoreceptors of the presynaptic cell, triggering a throttling of serotonin production.
		Selective serotonin reuptake inhibitors: {Alaproclate} {Etoperidone} {Citalopram} {Escitalopram} {Fluoxetine} {Fluvoxamine} {Paroxetine} {Sertraline} {Zimelidine}
	www.reboom.com /article/Selective_serotonin_reuptake_inhibitor.html (2250 words)

	Selective Serotonin Reuptake Inhibitors - Drug Comparisons - Compare Drugs - DrugDigest
		If serotonin levels are low, it is difficult for nerve endings in the brain to communicate well with each other.
		The selective serotonin reuptake inhibitors (SSRIs) block the ability of the nerve endings to bind and break down serotonin so that more serotonin is available to help the brain process nerves messages more efficiently and correctly.
		Is baseline agitation a relative contraindication for a selective serotonin reuptake inhibitor: a comparative trial of fluoxetine versus imipramine.
	www.drugdigest.org /DD/Comparison/NewComparison/0,10621,67-11,00.html (1483 words)

	Selective Serotonin Reuptake Inhibitors (SSRIs)
		When serotonin is released in the brain, it is reabsorbed by the brain cells to be used at another time for another message.
		Not surprisingly, serotonin receptors are especially plentiful in the areas of the brain controlling emotion.
		While it's apparent that serotonin is of vital importance in the development of depression, scientists aren't so sure that it's a simple cause-and-effect relationship; the brain's biochemical pathways for emotion and mood are just too complex.
	www.webmd.com /content/article/87/99352.htm (1485 words)

	Selective serotonin reuptake inhibitor definition - Depression symptoms, causes, and treatments including clinical and ...
		Selective serotonin reuptake inhibitor definition - Depression symptoms, causes, and treatments including clinical and manic depression.
		Selective serotonin reuptake inhibitor: A selective serotonin reuptake inhibitor (SSRI) is one of the commonly prescribed drugs for treating depression.
		This process is termed "reuptake." SSRIs work by inhibiting the reuptake of serotonin, an action which allows more serotonin to be available to be taken up by other nerves.
	www.medterms.com /script/main/art.asp?articlekey=10864 (257 words)

	Serotonin-norepinephrine reuptake inhibitor - Wikipedia, the free encyclopedia
		Serotonin-norepinephrine reuptake inhibitors (SNRIs) are a class of antidepressant used in the treatment of clinical depression and other affective disorders.
		This can be contrasted with the more widely-used selective serotonin reuptake inhibitors (SSRIs), which act only on serotonin.
		Activity on norepinephrine reuptake is thought necessary for an antidepressant to be effective on neuropathic pain, a property shared with the older tricyclic antidepressants but not with the SSRIs.
	en.wikipedia.org /wiki/Serotonin-norepinephrine_reuptake_inhibitor (690 words)

	Selective Serotonin Reuptake Inhibitors
		Selective Serotonin Reuptake Inhibitors (SSRIs) are a group of antidepressants that includes drugs such as citalopram (brand name of Celexa), fluoxetine (brand name of Prozac), paroxetine (brand name of Paxil) and sertraline (brand name of Zoloft).
		Selective serotonin reuptake inhibitors (SSRIs) are relatively new antidepressant medicines which, doctors believe, relieve depression by making more of the brain chemical serotonin available to activate nerve cells.
		The first two drugs are selective serotonin reuptake inhibitors, while the others have different acute pharmacological effects.
	www.healthinsite.gov.au /topics/Selective_Serotonin_Reuptake_Inhibitors (504 words)

	eMedicine - Toxicity, Selective Serotonin Reuptake Inhibitor : Article by Mohamed Badawy, MD (Site not responding. Last check: 2007-08-19)
		Serotonin binds one of seven postsynaptic 5-hydroxytryptophan (5-HT) receptors.
		Serotonin and 5-hydoxyindolacetic acid measurement: Although serotonin and its metabolite (5-hydroxyindolacetic acid) can be measured, this data would not be readily available and, therefore, would have limited clinical utility.
		Spirko BA, Wiley JF 2nd: Serotonin syndrome: a new pediatric intoxication.
	www.emedicine.com /ped/topic2786.htm (3511 words)

	The Selective Serotonin Reuptake Inhibitor Citalopram Induces the Storage of Serotonin in Catecholaminergic Terminals ...
		The Selective Serotonin Reuptake Inhibitor Citalopram Induces the Storage of Serotonin in Catecholaminergic Terminals -- Suarez-Roca and Cubeddu 302 (1): 174 -- Journal of Pharmacology And Experimental Therapeutics
		The observation that nomifensine, an inhibitor of the catecholamine neuronal transporter, antagonized the increase in efflux
		Manfridi A, Clavenna A and De Simoni MG (1992) Serotonin uptake inhibition: in vivo effect of sertraline in rats.
	jpet.aspetjournals.org /cgi/content/full/302/1/174 (3846 words)

	SELECTIVE SEROTONIN REUPTAKE INHIBITOR (Site not responding. Last check: 2007-08-19)
		These agents work by selectively inhibiting the reuptake of the neurotransmitter 5-hydroxytryptophan (serotonin) by the nerve cells.
		This leads to the accumulation of serotonin in the brain and increased serotonin stimulation.
		Increasing serotonin activity in the patient who is depressed appears to improve the condition in many patients.
	www.medhelp.org /glossary2/new/GLS_4151.HTM (133 words)

	Selective serotonin reuptake inhibitor treatment in the UK: risk of relapse or recurrence of depression -- CLAXTON et ...
		Selective serotonin reuptake inhibitor treatment in the UK: risk of relapse or recurrence of depression -- CLAXTON et al.
		Selective serotonin reuptake inhibitor treatment in the UK: risk of relapse or recurrence of depression
		Donoghue, J. Prescribing patterns of selective serotonin reuptake inhibitors in primary care: a naturalistic follow-up study.
	bjp.rcpsych.org /cgi/content/full/177/2/163 (3377 words)

	Selective serotonin reuptake inhibitors (SSRIs) for PMS and PMDD
		Selective serotonin reuptake inhibitors (SSRIs) can be taken orally every day, or only between the day you ovulate and your period (approximately the 2 weeks leading up to your period).
		An SSRI affects the brain's use of a chemical messenger (neurotransmitter) called serotonin.
		This improvement in serotonin use is known to be connected to and to improve physical and emotional PMS symptoms, depression, anxiety, hot flashes, and chronic pain.
	www.webmd.com /hw/womens_conditions/hw138203.asp (488 words)

	Platelet/Endothelial Biomarkers in Depressed Patients Treated With the Selective Serotonin Reuptake Inhibitor ...
		Role of thromboxane and serotonin as mediators in the development of spontaneous alterations in coronary blood flow and neointimal proliferation in canine models with chronic coronary artery stenoses and endothelial injury.
		Serotonin is associated with coronary artery disease and cardiac events.
		Serotonin as a mediator of cyclic flow variations in stenosed canine coronary arteries.
	circ.ahajournals.org /cgi/content/full/108/8/939 (3347 words)

	Guidelines for choice of selective serotonin reuptake inhibitor in depressive illness -- Anderson and Edwards 7 (3): ...
		Claxton, A. J., Li, Z. and McKendrick, J. (2000) Selective serotonin reuptake inhibitor treatment in the UK: risk of relapse or recurrence of depression.
		Goldstein, D. and Sundell, K. (1999) A review of the safety of selective serotonin reuptake inhibitors during pregnancy.
		Goodnick, P. and Goldstein, B. a) Selective serotonin reuptake inhibitors in affective disorders.
	apt.rcpsych.org /cgi/content/full/7/3/170 (4956 words)

	SSRI
		Block reuptake of Serotonin, less effect on Histaminic and Muscuranic receptors.
		SSRI should not be given to patients taking deprenyl for the risk of development of toxic serotonin syndrome.
		Adverse Effects of Selective Serotonin Reuptake Inhibitors - Arch of Family Medicine June 99
	www.neuroland.com /psy/ssri.htm (338 words)

	Maternal Selective Serotonin Reuptake Inhibitor Use During Pregnancy and Newborn Neurobehavior -- Zeskind and Stephens ...
		Emslie G, Judge R. Tricyclic antidepressants and selective serotonin reuptake inhibitors: use during pregnancy, in children/adolescents and in the elderly.
		Selective serotonin reuptake inhibitors in the treatment of affective disorders-III.
		Hansson SR, Hoffman BJ, Mezey E. Serotonin transporter messenger RNA in the developing rat brain: early expression in serotonergic neurons and transient expression in non-serotonergic neurons.
	pediatrics.aappublications.org /cgi/content/full/113/2/368 (5657 words)

	Portal infusion of a selective serotonin reuptake inhibitor enhances hepatic glucose disposal in conscious dogs -- ...
		Portal infusion of a selective serotonin reuptake inhibitor enhances hepatic glucose disposal in conscious dogs -- Moore et al.
		Serotonin (5-hydroxytryptamine), a novel regulator of glucose transport in rat skeletal muscle.
		Wieczorek I, Schulz C, Jarry H, and Lehnert H. The effects of the selective serotonin reuptake-inhibitor fluvoxamine on body weight in Zucker rats are mediated by corticotropin-releasing hormone.
	ajpendo.physiology.org /cgi/content/full/287/6/E1057 (4200 words)

	Selective serotonin reuptake inhibitor - Wikipedia, the free encyclopedia (via CobWeb/3.1 planetlab1.tamu.edu) (Site not responding. Last check: 2007-08-19)
		One of the "side effects" of high doses of L-dopa used at that time in about 10% of Parkinson patients was an increased sexual activity caused by L-dopa being a serotonin antagonist.
		We independently did the same experiment by injecting rats with para-chlorophenylalanine and measuring the reduction in serotonin levels.
		We also observed the rats' behavior and correlated the reduced serotonin level to a greatly increased level of sexual activity.
	en.wikipedia.org.cob-web.org:8888 /wiki/Selective_serotonin_reuptake_inhibitor (2587 words)

	In vitro biotransformation of the selective serotonin reuptake inhibitor citalopram, its enantiomers and demethylated ... (Site not responding. Last check: 2007-08-19)
		In vitro biotransformation of the selective serotonin reuptake inhibitor citalopram, its enantiomers and demethylated metabolites by monoamine oxidase in rat and human brain preparations
		This study was conducted to identify enzyme systems eventually catalysing a local cerebral metabolism of citalopram, a widely used antidepressant of the selective serotonin reuptake inhibitor type.
		The metabolism of citalopram, of its enantiomers and demethylated metabolites was investigated in rat brain microsomes and in rat and human brain mitochondria.
	www.nature.com /mp/journal/v7/n2/abs/4000946a.html (346 words)

	Interaction of a selective serotonin reuptake inhibitor with insulin in the control of hepatic glucose uptake in ...
		Interaction of a selective serotonin reuptake inhibitor with insulin in the control of hepatic glucose uptake in conscious dogs -- Moore et al.
		Articles by Moore, M. Articles by Cherrington, A. Interaction of a selective serotonin reuptake inhibitor with insulin in the control of hepatic glucose uptake in conscious dogs
		Portal infusion of a selective serotonin reuptake inhibitor enhances hepatic glucose disposal in conscious dogs.
	ajpendo.physiology.org /cgi/content/full/288/3/E556 (3990 words)

	Antiplatelet Activity During Coadministration of the Selective Serotonin Reuptake Inhibitor Paroxetine and Aspirin in ...
		Antiplatelet Activity During Coadministration of the Selective Serotonin Reuptake Inhibitor Paroxetine and Aspirin in Male Smokers: A Randomized, Placebo-Controlled, Double-blind Trial -- Kotzailias et al.
		Articles by Kotzailias, N. Articles by Jilma, B. Antiplatelet Activity During Coadministration of the Selective Serotonin Reuptake Inhibitor Paroxetine and Aspirin in Male Smokers: A Randomized, Placebo-Controlled, Double-blind Trial
		reuptake inhibitors for vascular diseases, bleeding events were
	jcp.sagepub.com /cgi/content/abstract/46/4/468?rss=1 (280 words)

	Selective Serotonin Reuptake Inhibitor - SSRIs
		SSRI's selective serotonin reuptake inhibitors were developed in the 1980's and are the most common prescribed today.
		In the most extreme cases, such a combination of medications (e.g., an SSRI and an MAOI) may result in a potentially serious or even fatal "serotonin syndrome," characterized by fever, confusion, muscle rigidity, and cardiac, liver, or kidney problems.
		Antidepressant-like profile and effects of rolipram (selective inhibitor of cyclic AMP) in the central nervous system.
	www.depression-guide.com /selective-serotonin-reuptake-inhibitors.htm (615 words)

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