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Topic: Sensitivity (human)


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In the News (Sat 19 Dec 09)

  
  Sensitivity of Human Ear
This incredible sensitivity is enhanced by an effective amplification of the sound signal by the outer and middle ear structures.
In addition to its remarkable sensitivity, the human ear is capable of responding to the widest range of stimuli of any of the senses.
The structures of the outer and middle ear contribute to both the remarkable sensitivity and the wide dynamic range of human hearing.
hyperphysics.phy-astr.gsu.edu /hbase/sound/earsens.html   (513 words)

  
 Thymidine Phosphorylase Mediates the Sensitivity of Human Colon Carcinoma Cells to 5-Fluorouracil -- Schwartz et al. ...
Human TP has been reported to be identical to the angiogenic factor platelet-derived endothelial cell growth factor (PD-ECGF)(11, 12, 13), and studies indicate that the catalytic activity of the enzyme is indispensable for its angiogenic effects(14, 15, 26).
Human colon carcinoma HT-29 cells were maintained in RPMI 1640 with 10% heat-inactivated fetal bovine serum and gentamicin, in a humidified CO incubator at 37 °C. Recombinant human thymidine phosphorylase (also known as platelet-derived endothelial cell growth factor) was obtained from Rand Systems (Minneapolis, MN).
A human ovarian cancer cell line derived from a biopsy of a FUra-resistant tumor was found to have a 70% reduction in TP activity and FdUMP levels compared to a cell line derived from the tumor in the same patient prior to the development of FUra resistance(36).
www.jbc.org /cgi/content/full/270/32/19073   (4182 words)

  
 Evolution of taste receptor may have shaped human sensitivity to toxic compounds
It is widely believed that behavioral and dietary choices may have reduced the importance of such chemical perception in higher primates, and particularly in humans.
The research team analyzed the nucleotide sequence of a human gene encoding a bitter-taste receptor that mediates recognition of a class of naturally ubiquitous, but toxic, cyanide-releasing compounds.
By analyzing sequences from a large sample of individuals representing 60 human populations, the researchers found evidence that specific variants of the receptor gene have been strongly favored in the early stages of human evolution.
www.eurekalert.org /pub_releases/2005-07/cp-eot072005.php   (364 words)

  
 Maximum Sensitivity Region of Human Hearing   (Site not responding. Last check: 2007-09-17)
This is associated with the resonance of the auditory canal.
There is another enhanced sensitivity region at about 13,500 Hz which may be associated with the third harmonic resonance of the auditory canal.
The maximum sensitivity regions of human hearing can be modeled as closed tube resonances of the auditory canal.
hyperphysics.phy-astr.gsu.edu /hbase/sound/maxsens.html   (125 words)

  
 Sensitivity (human) - Wikipedia, the free encyclopedia
This article is about the human feeling of insensitivity.
The sensitivity or insensitivity of a human, often considered with regard to a particular kind of stimulus, is the strength of the feeling it results in, in comparison with the strength of the stimulus.
A person with sensitive skin, which easily becomes painful or inflamed.
en.wikipedia.org /wiki/Sensitivity_(human)   (177 words)

  
 PHOTOPIC LUMINOUS EFFICIENCY FUNCTION OF THE HUMAN RETINA
The complete spectral sensitivity of the human eye is shown in the following figure under a variety of conditions.
The darkest area is the region generally described as the scotopic spectral sensitivity function or frequently the "scotopic luminous efficiency function." The heavy line enclosing the scotopic area and the lighter gray area on the right defines the photopic spectral sensitivity function or the "photopic luminous efficiency function.
The common wisdom has been that the human eye has no ultraviolet sensitivity and that its response to ultraviolet light was due to fluorescence within the eye.
www.4colorvision.com /files/photopiceffic.htm   (1472 words)

  
 Effects of discontinuation of zidovudine treatment on zidovudine sensitivity of human immunodeficiency virus type 1 ...
This reduction is due to mutations causing amino acid substitutions at five codons (41, 67, 70, 215, and 219) on the reverse transcriptase enzyme of HIV.
Sensitivity could be determined for six isolate pairs: one showed a decline in the 50% inhibitory zidovudine concentration after therapy discontinuation; four pairs did not show a change.
This study of isolates from a small group of individuals at different stages of disease, who had been taking zidovudine for 1 to 2 years, shows that a period of 1 year without zidovudine may be required to achieve a change from a mutant or mixed virus population to a wild-type virus population.
www.aegis.com /aidsline/1993/dec/M93C0103.html   (503 words)

  
 Reflections on the Ethos of the Human Body in Works of Artistic Culture
The artistic objectivation [sic] of the human body in its male and female nakedness, in order to make it first of all a model and then the subject of the work of art, is always to a certain extent a going outside of this original and, for the body, its specific configuration of interpersonal donation.
The process of refining personal human sensitivity is certainly a factor and fruit of culture.
In this way, in the processes of human culture understood in the wide sense, we note—even in man's state of hereditary sinfulness—quite an explicit continuity of the nuptial meaning of the body in its masculinity and femininity.
www.ewtn.com /library/PAPALDOC/JP2TB60.HTM   (1263 words)

  
 Electrostatic Discharge Association
Damage to an ESDS device by the ESD event is determined by the device's ability to dissipate the energy of the discharge or withstand the current levels involved.
The Human Body Model is the oldest and most commonly used model for classifying device sensitivity to ESD.
They allow easy grouping and comparing of components according to their ESD sensitivity and the classification gives you an indication of the level of ESD protection that is required for the component.
www.esda.org /esdbasics5.htm   (1703 words)

  
 Human Vision
The human vision system perceives images in colour using receptors on the retina of the eye which respond to three relatively broad colour bands in the regions of red, green and blue (RGB) in the colour spectrum (red, orange, yellow, green, blue, indigo, violet).
The vertical scale is the contrast sensitivity of human vision, which is the ratio of the maximum visible range of intensities to the minimum discernible peak-to-peak intensity variation at the specified frequency.
A final feature of human vision, which is useful for compression, is that the contrast sensitivity to a given pattern is reduced in the presence of other patterns (activity) in the same region.
cnx.org /content/m11084/latest   (1093 words)

  
 Oxytocin increases the [Ca2+]i sensitivity of human myometrium during the falling phase of phasic contractions -- ...
Oxytocin increases the [Ca2+]i sensitivity of human myometrium during the falling phase of phasic contractions -- McKillen et al.
Oxytocin receptors and human parturition: a dual role for oxytocin in the initiation of labor.
Oxytocin-stimulated phosphoinositide hydrolysis in human myometrial cells: involvement of pertussis toxin-sensitive and -insensitive G-proteins.
ajpendo.physiology.org /cgi/content/full/276/2/E345   (3280 words)

  
 Color, Part I: Human Perception
I'll first discuss the human notion of color (this month), and next move into why color is such a vital measurement in astronomy.
However, for most people, red cones are sensitive over a broad range of wavelengths from 0.4 to 0.8 microns and peak at about 0.58 microns; green cones have sensitivity over the same range, but peak at about 0.54 microns and have a relative shift over the range of typically 0.03 microns.
In your article you explain that the red cones are sensitive at the shortest visible wavelengths, and that this explains why violet appears to us to be a mixture of red and blue light, even though the...
www.suite101.com /article.cfm/astronomy/31240   (517 words)

  
 Electromagnetic Field Sensitivity
Of the 75, 25 had no reactions to blanks, whereas 50 did, and thus were discarded from the study; even though we felt that some of the reactions to blanks might be evidence of delayed reaction to previous frequencies, or prolonged response to the previous positive challenge, as well as true placebo reactions.
As a result of the weak field levels and short exposure time, the responses were mild except in two patients whose symptoms were so severe (e.g., drop attack, severe itching) that they received intravenous vitamin C, magnesium, and oxygen as a result of the prolonged and delayed reactions.
It is clear that EMF sensitivity is a real phenomenon in some environmentally sensitive patients, because some had consistent reactions while none of the controls did.
www.aehf.com /articles/em_sensitive.html   (2925 words)

  
 Good news for "wusses": Research links pain sensitivity to gene
People vary greatly in their sensitivity to pain: A tetanus shot's pinprick for one person is another's misery.
The researchers were the first to identify sections of the human and rodent mu receptor gene almost a decade ago.
The human studies trail the mouse ones, says Uhl, but they, too, suggest the same relation between gene variation, numbers of receptors and relief of pain.
www.eurekalert.org /pub_releases/1999-07/JHMI-GnfR-190799.php   (757 words)

  
 In Vivo Sensitivity of Human Melanoma to Tumor Necrosis Factor (TNF)-{{alpha}} Is Determined by Tumor Production of the ...
the in vitro and in vivo sensitivity of the tumor to TNF.
Human tumors were inoculated in the hind limb-flank region by s.c.
In vivo and in vitro TNF sensitivity of wild-type 1286 and Pmel melanomas.
cancerres.aacrjournals.org /cgi/content/full/59/1/205   (5291 words)

  
 Neutralization Sensitivity of Human Immunodeficiency Virus Type 1 Primary Isolates to Antibodies and CD4-Based ...
Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120.
Neutralization sensitivity of human immunodeficiency virus type 1 is determined in part by the cell in which the virus is propagated.
Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus populations.
jvi.asm.org /cgi/content/full/72/3/1876   (7191 words)

  
 Human Hearing: Amplitude Sensitivity Part 1
Much is made of the ear’s sensitivity at the mid and upper-mid range portions of the audible spectrum (as well it should be), but the realities presented by the ELLC all add up to the requirement of low-level LF distortion that cannot be ignored either, where it comes to the accurate reproduction of music.
And that’s just as sensitive as the ear needs to be: were it any more sensitive than that, we’d be treated to the never-ending white noise of molecular density fluctuations, or Brownian movement.
The resultant range is owing to varying methodologies used by the researchers and, of course, the response of the human hearing apparatus to the applied acoustic signals.
www.audioholics.com /techtips/roomacoustics/HumanHearingAmplitude.php   (1921 words)

  
 Electrostatic Discharge Association: Fundamentals of ESD
In Part Two of this series, we indicated that a key element in a successful static control program was the identification of those items (components, assemblies, and finished products) that are sensitive to ESD and the level of their sensitivity.
One of the most common causes of electrostatic damage is the direct transfer of electrostatic charge through a significant series resistor from the human body or from a charged material to the electrostatic discharge sensitive (ESDS) device.
Device failure models and device test methods define the sensitivity of the electronic devices and assemblies to be protected from the effects of ESD.
www.esda.org /basics/part5.cfm   (1849 words)

  
 Improved Photometer
The photometer measures only a third of the visual spectrum and is blind to the remaining two/thirds.  Now ask any 100 pro photographers whether the sensitivity of their $500 light meter is based on the sensitivity of film or on the sensitivity of the human brain?  Careful now, it could be a trick question.
Two primary curves for human spectral sensitivity have been standardized by means of the psychophysical techniques of brightness equivalence matching as a function of radiance and wavelength.
The CIE adopted the CIE standard photopic observer in 1931 for the fully light-adapted human observer and the CIE standard scotopic observed in 1951 for the dark-adapted human observer.
www.plumeltd.com /Photometer.htm   (1094 words)

  
 [No title]
With single-blind, placebo-controlled screening challenges, 100 subjects with asthma (30 subjects with a history of Oriental restaurant asthma attacks; 70 subjects with a negative history) were challenged with 2.5 g of MSG.
MSG challenges in subjects with and without a perceived sensitivity to MSG failed to induce signs or symptoms of asthma.
Those who had a history of oriental asthma attacks found that their problems were not a result of MSG, but were able to identify other causes, including food allergies and heartburn caused by overeating.
www.msgfacts.com /safety/msgsafety16.html   (646 words)

  
 Myofibrillar Calcium Sensitivity of Isometric Tension Is Increased in Human Dilated Cardiomyopathies . Role of Altered ...
Myofibrillar Calcium Sensitivity of Isometric Tension Is Increased in Human Dilated Cardiomyopathies.
Hajjar, R.J. Gwathmey, G.M. Briggs, and J.P. Morgan (1988) Differential effect of DPI on the sensitivity of the myofilaments to Ca in intact and skinned trabeculae from control and myopathic human hearts.
Taylor, and H.S. Slayter (1992) Light chain 2 profile and activity of human ventricular myosin during dilated cardiomyopathy: identification of a causal agent for impaired myocardial function.
www.jci.org /cgi/content/full/98/1/167   (5493 words)

  
 Quantitative Analyses of Dynamic Strain Sensitivity in Human Skin Mechanoreceptors -- Edin 92 (6): 3233 -- Journal of ...
Collins DF and Prochazka A. Movement illusions evoked by ensemble cutaneous input from the dorsum of the human hand.
Grill SE and Hallett M. Velocity sensitivity of human muscle spindle afferents and slowly adapting type II cutaneous mechanoreceptors.
Tactile sensibility in the human hand: receptive field characteristics of mechanoreceptive units in the glabrous skin area.
jn.physiology.org /cgi/content/full/92/6/3233   (6367 words)

  
 Transient adenoviral N-methylpurine DNA glycosylase overexpression imparts chemotherapeutic sensitivity to human breast ...
Methoxyamine sensitizes cells to the effects of alkylation by MMS, but this effect is dramatically increased for HA-MPG-overexpressing cells for both MMS and temozolomide.
The sensitivity to alkylation caused by MPG overexpression is
sensitivity was inferred from the observation that overexpressing
mct.aacrjournals.org /cgi/content/full/3/8/955   (7007 words)

  
 Sphingosine-1-Phosphate Lyase Regulates Sensitivity of Human Cells to Select Chemotherapy Drugs in a p38-Dependent ...
sensitivity to cisplatin and carboplatin as predicted from the
increases the sensitivity of the cells to cisplatin.
this enzyme to cisplatin sensitivity strengthen this correlation.
mcr.aacrjournals.org /cgi/content/full/3/5/287   (5315 words)

  
 CDC25B and p53 Are Independently Implicated in Radiation Sensitivity for Human Esophageal Cancers -- Miyata et al. 6 ...
in the sensitivity of cancer cells for radiation therapy.
sensitivity both in vitro and in vivo (23, 24).
Hoffmann I., Draetta G., Karsenti E. Activation of the phosphatase activity of human cdc25A by a cdk2-cyclin E dependent phosphorylation at the G1/S transition.
clincancerres.aacrjournals.org /cgi/content/full/6/12/4859   (4324 words)

  
 Sensitivity of human type II topoisomerases to DNA damage: stimulation of enzyme-mediated DNA cleavage by abasic, ...
Sensitivity of human type II topoisomerases to DNA damage: stimulation of enzyme-mediated DNA cleavage by abasic, oxidized and alkylated lesions -- Sabourin and Osheroff 28 (9): 1947 -- Nucleic Acids Research
Sensitivity of human type II topoisomerases to DNA damage: stimulation of enzyme-mediated DNA cleavage by abasic, oxidized and alkylated lesions
Human topoisomerase II was used as the experimental model for
nar.oxfordjournals.org /cgi/content/full/28/9/1947   (4242 words)

  
 Fas-mediated Signaling Enhances Sensitivity of Human Soft Tissue Sarcoma Cells to Anticancer Drugs by Activation of p38 ...
Fas-mediated Signaling Enhances Sensitivity of Human Soft Tissue Sarcoma Cells to Anticancer Drugs by Activation of p38 Kinase
Sensitivity of human soft tissue sarcoma (STS) cells to methotrexate,
Human Sarcoma Cells Express Fas and Fas-L. The expression of Fas and Fas-L protein was examined in six
mct.aacrjournals.org /cgi/content/full/1/14/1343   (3753 words)

  
 AN IN VITRO LARVAL MOTILITY ASSAY TO DETERMINE ANTHELMINTIC SENSITIVITY FOR HUMAN HOOKWORM AND STRONGYLOIDES SPECIES -- ...
The assay was unsuitable for examination of sensitivity to albendazole
Failure of mebendazole in treatment of human hookworm infections in the southern region of Mali.
In vitro studies on the relative sensitivity to ivermectin of Necator americanus and Ancylostoma ceylanicum.
www.ajtmh.org /cgi/content/full/71/5/608   (4564 words)

  
 Interleukin-12 Enhances the Sensitivity of Human Osteosarcoma Cells to 4-Hydroperoxycyclophosphamide by a Mechanism ...   (Site not responding. Last check: 2007-09-17)
Interleukin-12 Enhances the Sensitivity of Human Osteosarcoma Cells to 4-Hydroperoxycyclophosphamide by a Mechanism Involving the Fas/Fas-Ligand Pathway -- Duan et al.
Interleukin-12 Enhances the Sensitivity of Human Osteosarcoma Cells to 4-Hydroperoxycyclophosphamide by a Mechanism Involving the Fas/Fas-Ligand Pathway
the sensitivity of human OS cells to alkylating agents.
clincancerres.aacrjournals.org /cgi/content/full/10/2/777   (3086 words)

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