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Topic: Sertoli cell

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	Sertoli-Sertoli and Sertoli-Germ Cell Interactions and Their Significance in Germ Cell Movement in the Seminiferous ...
		of germ cell migration in the seminiferous epithelium.
		Sertoli cells are indispensable to the release of mature spermatids
		(163) and that germ cells and testicular macrophages
	edrv.endojournals.org /cgi/content/full/25/5/747 (9403 words)

	Endotext.com - Endocrinology Of Male Reproduction, Endocrinology of the Male Reproductive System
		Further examples of the involvement of Sertoli cells arise from their ability to produce locally, a range of proteins which are essential for spermatogenesis but cannot gain access to the seminiferous epithelium because of the blood-testis barrier.
		The close association between germ cells and Sertoli cells is reflected by the capacity for germ cells to influence the metabolic activity of the Sertoli cells.
		The data indicate that the metabolic activity of the Sertoli cell is influenced by the populations of germ cells that are found at a particular stage of the seminiferous cycle (69-71).
	www.endotext.org /male/male1/male1_2.htm (7209 words)

	Sertoli Cell Tumors of the Testis (Site not responding. Last check: 2007-10-19)
		To assess Sertoli cell differentiation in a rare malignant biphasic testicular tumor, we compared the immunophenotypic profile of the tumor with that of Sertoli cell nodules and adenomas and mullerian carcinosarcomas.
		Sclerosing Sertoli cell tumor of the testis: a distinct histological subtype.
		None of these cells stained with a variety of markers used for neoplastic germ cells, and in one case in which the non-neoplastic Sertoli cells were strongly reactive for inhibin but the neoplastic Sertoli cells were not, all the germ cells within the tumor occurred adjacent to inhibin-positive Sertoli cells.
	www.thedoctorsdoctor.com /diseases/testis_sertolicelltumor.htm (4258 words)

	Journal of Negative Results in BioMedicine \| Full text \| Cortactin and phagocytosis in isolated Sertoli cells
		Sertoli cell monocultures were incubated with or without follicle stimulating hormone (FSH; 0.1 μg/ml) in the presence or absence of cytochalasin D (2 μM), as an actin disrupter.
		Sertoli cells were isolated from 16-day-old Sprague-Dawley rats (Harlan) by sequential enzymatic digestion with trypsin and collagenase, as previously described by Cameron et al [23].
		Sertoli cells were fixed with 100% ethanol and immunostained for cortactin, as described by Wine and Chapin [25], using 10 μg/ml anti-cortactin (p80/p85), clone 4F11 (Upstate) as the primary antibody.
	www.jnrbm.com /content/4/1/11 (2626 words)

	Sertoli-Leydig Cell Tumor of the Ovary (Site not responding. Last check: 2007-10-19)
		Sertoli cell tumors of the ovary: a clinicopathologic and immunohistochemical study of 54 cases.
		The cells usually had pale to occasionally densely eosinophilic cytoplasm, but 6 tumors were composed of cells with prominent foamy cytoplasm, falling in the category of "lipid-rich" Sertoli cell tumor, and one had cells with clear non-foamy cytoplasm.
		Calcifying Sertoli cells neoplasms have been described in the testis, but this case appears to be the first description of a case with similar features in the ovary.
	www.thedoctorsdoctor.com /diseases/ovary_sertolileydig.htm (4060 words)

	Sertoli cell transplants show promise (Site not responding. Last check: 2007-10-19)
		These results suggest that sertoli cells may be implicated in the regeneration of damaged neural connections in PD, or possibly in prolonging the life of the remaining dopamine-producing neural cells.
		Sertoli cells appear both to promote the survival and growth of transplanted grafts via the production of growth factors, and to provide protection from brain microglia which form a component of the immune system.
		This vital first step in the clinical use of sertoli cells has huge potential in the treatment of PD. Dr Sanberg believes that the treatment of PD, and the slowing of its progression are dependent upon preventing neuronal cell death, which is beyond the scope of current therapy options.
	www.parkinsonsdisease.com /news/news9_arc.htm (417 words)

	College of Pharmacy : UT Austin
		The Sertoli cell of the seminiferous epithelium is recognized as the primary cellular target for phthalate-induced testicular injury based on Sertoli cell specific biochemical and morphological alterations.
		The Sertoli cell is responsible for orchestrating the differentiation of germ cells as well as providing their nutritional and physical support.
		In further characterizing the effects of MEHP on the Sertoli cell, the influence of MEHP on Sertoli cell vimentin filaments was investigated.
	www.utexas.edu /pharmacy/divisions/pharmtox/faculty/richburg/mechanisms.html (846 words)

	Sertoli cell - Wikipedia, the free encyclopedia
		The cell is also responsible for establishing and maintaining the spermatogonial stem cell niche, which ensures the renewal of stem cells and the differentiation of spermatogonia into mature germ cells that progress stepwise through the long process of spermatogenesis, ending in the release of spermatozoa.
		During the Maturation phase of spermiogenesis, the Sertoli cells consume the unneeded portions of the spermatazoa.
		Sertoli-Leydig cell tumour are part of the sex cord-stromal tumour group of ovarian neoplasms.
	en.wikipedia.org /wiki/Sertoli_cell (612 words)

	Sertoli Cell Tumor (Site not responding. Last check: 2007-10-19)
		A Sertoli cell tumor is a tumor in the testicles that involves the specific cells called Sertoli cells.
		Sertoli cell tumors are usually slow growing and noninvasive, although 10 to 20 percent may be malignant.
		Sertoli cell tumors are the most common tumors that cause a male feminizing syndrome due to changes in sex hormone production.
	www.petplace.com /dogs/sertoli-cell-tumor/page1.aspx (599 words)

	A rapid method of Sertoli cell isolation by DSA lectin, allowing mitotic analyses. (Site not responding. Last check: 2007-10-19)
		In addition, we have studied the proliferative activity of Sertoli cells isolated by lectin binding from rats of different ages.
		Sertoli cells exhibited a characteristic pattern of proliferation which was a function of the donor animal age.
		A similar pattern was observed when the mitotic activity of Sertoli cells in response to mitogens present in the testicular extracts from 5 day-old rats was evaluated.
	www.arclab.org /medlineupdates/abstract_10022769.html (269 words)

	Canine Reproduction Part 5
		Sertoli cell tumor: Sertoli cells are located on the walls of the seminiferous tubules within the testicles and support the development of the spermatozoa.
		Sertoli tumors present as a firm nodule on the testis, and may reach significant size prior to diagnosis in an abdominal testis.
		Interstitial cell tumors: Interstitial cell tumors originate from the Leydig cells of the testicle, which are testosterone-secreting cells.
	www.labbies.com /reproduction5.htm (5904 words)

	Sertoli cell nodules in the undescended testis: a histochemical, immunohistochemical, and ultrastructural study of ...
		Sertoli cell nodules in the undescended testis: a histochemical, immunohistochemical, and ultrastructural study of hyaline deposits -- Govender et al.
		Sertoli cell nodules in the undescended testis: a histochemical, immunohistochemical, and ultrastructural study of hyaline deposits
		Hyperplasia and the immature appearance of Sertoli cells in primary testicular disorders.
	jcp.bmj.com /cgi/content/full/57/8/802 (2246 words)

	Sertoli cell nodules in the undescended testis: a histochemical, immunohistochemical, and ultrastructural study of ...
		Sertoli cell nodules in the undescended testis: a histochemical, immunohistochemical, and ultrastructural study of hyaline deposits -- Govender et al.
		Sertoli cell nodules in the undescended testis: a histochemical, immunohistochemical, and ultrastructural study of hyaline deposits
		Hyperplasia and the immature appearance of Sertoli cells in primary testicular disorders.
	jcp.bmjjournals.com /cgi/content/full/57/8/802 (2246 words)

	Sertoli Cell Tumor (Site not responding. Last check: 2007-10-19)
		The reticulocytes (young, recently released red cells from the bone marrow) might be counted to determine whether the bone marrow was responding to the anemia appropriately by producing new young red cells.
		The preputial swabs of animals under the influence of elevated estrogen levels typically have cells that are cornified, which is a specific change in the cell characteristics that occur due to higher estrogen levels.
		The treatment of choice for Sertoli cell tumors, either scrotal or cryptorchid is the surgical removal of the affected testicle.
	www.petplace.com /dogs/sertoli-cell-tumor/page3.aspx (1394 words)

	Specific Staining of Sertoli Cell Nuclei and Evaluation of Sertoli Cell Number and Proliferative Activity in Meishan ...
		Stereological enumeration of Sertoli cells is a labor-intensive
		Sertoli cell development of pig testis in the fetal and neonatal period.
		Proliferation of spermatogonia and Sertoli cells in maturing mice.
	www.biolreprod.org /cgi/content/full/64/2/689 (4735 words)

	Population Council Projects \| Physiology of Sertoli Cells
		It was shown that the addition of cAMP or FSH to primary cultures of purified rat Sertoli cells results in a two- to three-fold increase in the metabolism of retinol to retinoic acid; the metabolism of retinol to retinyl esters, especially retinyl palmitate, was also increased by approximately five-fold relative to untreated Sertoli cells.
		Culture of the Sertoli cells in the presence of all-trans retinoic acid also increased the rate of retinol metabolism.
		These results indicate that one function of FSH (and/or cAMP) in Sertoli cells is to increase the metabolism of retinol to the biologically active metabolite retinoic acid and to retinyl esters.
	www.popcouncil.org /projects/BIO_PhysSertoliCells.html (763 words)

	An Ex Vivo Analysis of Sertoli Cell Actin Dynamics Following Gonadotropic Hormone Withdrawal -- Show et al. 25 (6): ...
		expression of the cofilin gene was unaffected in Sertoli cells
		Sertoli cell ectoplasmic specializations in the seminiferous epithelium of the testosterone-suppressed adult rat.
		Reduced intratesticular testosterone concentration alters the polymerization state of the Sertoli cell intermediate filament cytoskeleton by degradation of vimentin.
	www.andrologyjournal.org /cgi/content/full/25/6/1013 (4460 words)

	Sertoli cell definition - Dictionary - MSN Encarta
		Sertoli cell definition - Dictionary - MSN Encarta
		Search for "Sertoli cell" in all of MSN Encarta
		nourishing cell for sperm: a cell, found in large numbers lining the semen-producing tubules of the testis, that provides support and nourishment for developing sperm
	encarta.msn.com /dictionary_561535097/Sertoli_cell.html (88 words)

	StockInterview.com - Sertoli Cells: Mother Nature's Anti-Rejection Drug
		Islet cells are the beta cells (brown) in the pancreas responsible for producing the hormone insulin.
		It is the testicular Sertoli cell which keeps the human body's immune system from destroying a man's sperm.
		When the beta cells fail to produce insulin, or too little of it, sugar stagnates in the blood and is not moved into the cells to produce energy for the body.
	www.stockinterview.com /News/10042006/Sertoli.html (1495 words)

	Amazon.com: Sertoli Cell Biology, Volume 1: Books: Michael K. Skinner,Michael D. Griswold (Site not responding. Last check: 2007-10-19)
		It addresses such highly topical areas as stem cells, genomics, and molecular genetics, as well as provides historical information on the discovery of this type of cell, and the pathophysiology of male infertility.
		Enrico Sertoli was 18 years old when he began his studies in medicine and research at the University of Pavia in Northern Italy in 1860 (3).
		Cell Endocrinol, Cell Biol, New York, Cell Res, Elsevier Science, Sinha Hikim, Tissue Cell, Cell Tissue Res, Cancer Res, Cell Sci, Enrico Sertoli, Genes Der, Nucleic Acids Res, The Physiology of Reproduction, Kim Boekelheide, Brain Res, Lonnie Russell, Rajpert-De Meyts, Recent Prog, Biology of Reproduction, Nobel Prize, Steroid Biochem, Belo Horizonte, Cell Biochem, Cell Motil
	www.amazon.com /Sertoli-Cell-Biology-Michael-Skinner/dp/0126477515 (936 words)

	Enrico Sertoli (www.whonamedit.com)
		A rare and usually benign hormone-producing tumour in the testicle originating from Leydig interstitial cells or similar hilu cells in the ovary.
		Enrico Sertoli Sertoli was born in Sondrio, Valtellina, the upper valley of the Adda River from its sources in the Ortles mountains westward to its entry into Lake Como.
		From 1870 to 1907 Sertoli was professor of anatomy and physiology, and after 1907 of physiology only, at the Advanced Royal School of Veterinary Medicine in Milan, which, at that time, enjoyed university status.
	www.whonamedit.com /doctor.cfm/556.html (455 words)

	Sertoli-Leydig cell tumor
		The Sertoli cells, which are located in the male gonads (the testes), provide nourishment to the sperm cells.
		The Leydig cells secrete the male sex hormone testosterone.
		Arrhenoblastomas are a type of ovary tumor whose cells (Sertoli-Leydig cells) produce and secrete a male sex hormone, causing virilization (male physical characteristics such as facial hair and deep voice) in women.
	www.mercydesmoines.org /ADAM/Encyclopedia/ency/001172.asp (199 words)

	eMedicine - Sertoli-Cell-Only Syndrome : Article by Edward David Kim, MD, FACS
		As an example, Klinefelter syndrome is characterized by SCO and Leydig cell hyperplasia.
		A congenital absence of germ cells due to failure of migration of gonocytes is theoretically possible.
		Nistal M, Jimenez F, Paniagua R: Sertoli cell types in the Sertoli-cell-only syndrome: relationships between Sertoli cell morphology and aetiology.
	www.emedicine.com /med/topic2104.htm (2016 words)

	Selective Loss of Sertoli Cell and Germ Cell Function Leads to a Disruption in Sertoli Cell-Germ Cell Communication ...
		Selective Loss of Sertoli Cell and Germ Cell Function Leads to a Disruption in Sertoli Cell-Germ Cell Communication During Aging in the Brown Norway Rat -- Syed and Hecht 64 (1): 107 -- Biology of Reproduction
		Selective Loss of Sertoli Cell and Germ Cell Function Leads to a Disruption in Sertoli Cell-Germ Cell Communication During Aging in the Brown Norway Rat
		receptor and a novel gene, are induced in Sertoli cells by meiotic
	www.biolreprod.org /cgi/content/abstract/64/1/107 (434 words)

	PRESS RELEASE Pheromone Builds Scientific Advisory Board: Sertoli Cell Expert Dr. Jannette Dufour to Help Develop ... (Site not responding. Last check: 2007-10-19)
		Currently Assistant Professor in the Department of Cell Biology and Biochemistry at Texas Tech University Health Sciences Center in Lubbock Texas, Dr. Dufour's research was instrumental in developing the technology leading to some of the Sertoli cell patents now licensed exclusively to Pheromone.
		While there she received five postdoctoral fellowships to study the use of Sertoli cells as a way to immunoprotect transplanted islets.
		Dufour is now an Assistant Professor at Texas Tech University Health Sciences Center where she continues to investigate the immunoprotective properties of Sertoli cells with the goal of developing ways to improve the survival of transplanted islets.
	www.marketwire.com /mw/release_html_b1?release_id=149476&tsource=3 (351 words)

	Research Corporation Technologies \| Bioventures \| Sertoli Technologies Inc.
		The Sertoli Technologies Inc. technology is based on work at the University of Tennessee Medical Center that showed Sertoli cells protect foreign islets from rejection by producing immune inhibitors directly at the graft site.
		The technology harnesses Sertoli cells' natural ability to modulate the immune system to create a local immunoprivileged site for therapeutic-cell transplantation and cell-based gene therapy.
		Sertoli cells protect themselves and other co-transplanted cell types from destruction by the host's immune system without the need for chronic use of immunosuppressive drugs.
	www.rctech.com /bioventures/sertoli.php (317 words)

	AllRefer Health - Sertoli-Leydig Cell Tumor (Arrhenoblastoma)
		The Sertoli cells, which are located in the male gonads, provide nourishment to the sperm cells.
		The Leydig cells secrete the male sex hormone testosterone.
		Arrhenoblastomas are a type of ovarian tumor whose cells (Sertoli-Leydig cells) produce and secrete a male sex hormone, causing virilization (the appearance of male physical characteristics) in women.
	health.allrefer.com /health/sertoli-leydig-cell-tumor-info.html (281 words)

	PRESS RELEASE Sernova's Sertoli Cell Research Hopes to Replace Anti-Rejection Drugs in Edmonton Protocol Islet ... (Site not responding. Last check: 2007-10-19)
		To overcome the immune system response, Sernova's proposed solution is to use the Sertoli cell's proven ability to create a immunologically protected environment for transplanted cells.
		The working hypothesis presupposes that once islets and Sertoli cells are injected into a small vascularized chamber implanted below the skin, the islets can produce insulin in response to the body's demands while the Sertoli cells protect the islets by masking their presence from the immune system.
		The Company owns the exclusive rights to over 20 patents related to the therapeutic use of Sertoli cells.
	www.marketwire.com /mw/release_html_b1?release_id=168372 (491 words)

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