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Topic: Sertraline

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	Sertraline - Wikipedia, the free encyclopedia
		Sertraline is used medically mainly to treat the symptoms of depression and anxiety.
		Sertraline can have adverse effects, including: insomnia, asthenia, gastrointestinal complaints, tremors, confusion, dizziness, anorgasmia, and decreased libido; it can induce mania or hypomania in around 0.5% of patients.
		Sertraline is manufactured by Pfizer and sold as Zoloft in the United States as small green 25 mg tablets, blue 50 mg tablets, and yellow 100 mg tablets (Generic 100 mg sertraline tablets are also yellow), each of which is scored to allow easy halving.
	en.wikipedia.org /wiki/Sertraline (1839 words)

	SERTRALINE
		Sertraline and norsertraline plasma levels were measured in 3 mother-infant pairs, with maternal doses ranging from 50 to 100 mg/day.
		Sertraline levels were less than 2 ng/mL in 7 of the infants, and the metabolite levels were also low, less than or equal to 6 ng/mL, in 7 of the infants.
		A 9-year-old ingested an unknown quantity of sertraline and presented to the emergency department with tachycardia, hypertension, hallucinations, hyperthermia, vasodilation, and tremors in all extremities.
	www.antidepressantsfacts.com /sertraline2.htm (3099 words)

	Sertraline ~Zoloft
		The pharmacokinetics of sertraline have not been studied in patients with renal impairment and, until adequate numbers of patients with mild, moderate or severe renal impairment have been evaluated during chronic treatment with sertraline, it should be used with caution in such patients.
		The safety of sertraline during pregnancy and lactation has not been established and therefore, it should not be used in women of childbearing potential or nursing mothers, unless, in the opinion of the physician, the potential benefits to the patient outweigh the possible hazards to the fetus.
		Although sertraline did not potentiate the cognitive and psychomotor effects of alcohol in experiments with normal subjects, the concomitant use of sertraline and alcohol in depressed patients has not been studied and is not recommended.
	endoflifecare.tripod.com /huntdiseasefaqs/id52.html (1403 words)

	Mosby's Drug Consult Top 200
		Sertraline hydrochloride is a white crystalline powder that is slightly soluble in water and isopropyl alcohol, and sparingly soluble in ethanol.
		Sertraline plasma clearance in a group of 16 (8 male, 8 female) elderly patients treated for 14 days at a dose of 100 mg/day was approximately 40% lower than in a similarly studied group of younger (25-32 years old) individuals.
		Sertraline and other SSRIs may also have clinical utility in a number of other disorders including eating disorders, substance abuse, headaches, and social phobia, although none of these uses is approved by the FDA for sertraline.
	www.mosbysdrugconsult.com /DrugConsult/Top_200/Drugs/e3087.html (11952 words)

	Sertraline
		Sertraline is used to treat depression, control feelings of panic, and obsessions and compulsions that interfere with daily living.
		Sertraline has the potential to interact with over-the-counter medications and herbal compounds so it is important that your physician or pharmacist knows about other products you are taking.
		Sertraline has been found in the milk but at as significantly lower concentration than in the blood of the person taking the medication.
	www.tthhivclinic.com /sertraline.html (525 words)

	SERTRALINE
		Sertraline is a naphthylamine derivative that is a serotonin reuptake inhibitor used as an antidepressant.
		Hindmarch and Bhatti (1988) observed increases in objective measurements of alertness with sertraline in doses of 50, 75, and 100 milligrams in a double-blind, placebo-controlled study.
		Sertraline- induced serotonin syndrome was diagnosed (Pao and Tipnis, 1997).
	www.antidepressantsfacts.com /zoloft.htm (3088 words)

	Anxiety Zone - Sertraline
		Sertraline is used medically mainly to treat the symptoms of depression.
		Sertraline is manufactured by Pfizer as small green 25 mg tablets, blue 50 mg tablets, or off-yellow 100 mg tablets.
		One property of sertraline is that it appears to be also a minor inhibitor of dopamine reuptake.
	www.anxietyzone.com /drugs/sertraline.html (316 words)

	Zoloft Warnings, Precautions, Pregnancy, Nursing, Abuse - Sertraline Hcl - RxList Monographs
		A clinical study comparing sertraline pharmacokinetics in healthy volunteers to that in patients with renal impairment ranging from mild to severe (requiring dialysis) indicated that the pharmacokinetics and protein binding are unaffected by renal disease.
		When female rats received sertraline during the last third of gestation and throughout lactation, there was an increase in the number of stillborn pups and in the number of pups dying during the first 4 days after birth.
		The prescriber should be mindful that the evidence relied upon to conclude that sertraline is safe for use in children and adolescents derives from clinical studies that were 10 to 52 weeks in duration and from the extrapolation of experience gained with adult patients.
	www.rxlist.com /cgi/generic/sertral_wcp.htm (3302 words)

	Zoloft (Sertraline hydrochloride) 50mg 56 Tablets (Site not responding. Last check: 2007-10-21)
		Sertraline is a potent and specific inhibitor of neuronal serotonin (5-HT) uptake in vitro, which results in the potentiation of the effects of 5-HT in animals.
		Sertraline did not produce either the stimulation and anxiety associated with d-amphetamine or the sedation and psychomotor impairment associated with alprazolam.
		Since sertraline has not been evaluated in patients with a seizure disorder, it should be avoided in patients with unstable epilepsy and patients with controlled epilepsy should be carefully monitored.
	www.globaldrug.tv /product.asp?ProdID=1132&CtgID= (1392 words)

	Sertraline (PIM 177) (Site not responding. Last check: 2007-10-21)
		Diagnosis of sertraline poisoning is clinical and based on history of overdose and/or access to sertraline and the presence of minor neurological and/or gastroenterological symptoms.
		Sertraline is a potent inhibitor of serotonin re-uptake by central nervous system neurones and may interact with other drugs or circumstances which cause serotonin release.
		Sumatriptan: the manufacturer recommends to not prescribe sertraline concomitantly with sumatriptan, which is a selective agonist at serotonin type 1D receptors, because of possible hypertensive crises and severe coronary vasoconstriction, and advises a washout period of 1 week after cessation of sertraline.
	www.inchem.org /documents/pims/pharm/pim177.htm (3659 words)

	MedlinePlus Drug Information: Sertraline
		Sertraline is in a class of medications called selective serotonin reuptake inhibitors (SSRIs).
		To treat premenstrual dysphoric disorder, sertraline is taken once a day, either every day of the month or on certain days of the month.
		Sertraline is also used sometimes to treat headaches and sexual problems.
	www.nlm.nih.gov /medlineplus/druginfo/medmaster/a697048.html (1094 words)

	Sertraline Drug Information
		Sertraline (SER-tra-leen) is used to treat mental depression, obsessive-compulsive disorder, panic disorder, premenstrual dysphoric disorder, posttraumatic stress disorder, and social anxiety disorder.
		However, sertraline can cause a decrease in appetite and children who take this medicine for a long time should have their growth and body weight measured by the doctor at regular visits.
		Sertraline may be taken with or without food on a full or empty stomach.
	www.drugs.com /cons/Sertraline.html (2679 words)

	Sertraline
		Studies have shown that children and teenagers who take antidepressants ('mood elevators') such as sertraline may be more likely to think about harming or killing themselves or to plan or try to do so than children who do not take antidepressants.
		If your child’s doctor has prescribed sertraline for your child, you should watch his or her behavior very carefully, especially at the beginning of treatment and any time his or her dose is increased or decreased.
		Your child’s doctor will want to see your child often while he or she is taking sertraline, especially at the beginning of his or her treatment.Your child’s doctor may also want to speak with you or your child by telephone from time to time.
	www.safemedication.com /displaydrug.cfm?id=697048 (1058 words)

	9425SRN
		Single case report of dependence seen in a neonate whose mother had taken SRN 200mg/day throughout her pregnancy and for three weeks after the birth, when it was stopped abruptly.
		Sertraline was then resumed and increased to 200mg daily.
		Paroxetine (17), sertraline (4), fluoxetine (3), fluvoxamine (2).
	www.socialaudit.org.uk /9425srn.htm (1207 words)

	RemedyFind: patient ratings of Zoloft etc. (Sertraline) for Depression
		As Sertraline has a fairly long half life of approximately 26 hours (the amount of time before it is eliminated by the body), it can be taken once-daily, and discontinuation or withdrawal side-effects tend to be less than some other antidepressants with shorter half-lives.
		Sertraline was found to produce a significantly greater response than placebo for depression and anxiety and was well tolerated with the most frequent placebo adjusted adverse events, being nausea, diarrhea, insomnia and dry mouth.
		Sertraline may have advantages over the SSRIâs paroxetine, fluoxetine and fluvoxamine in elderly patients because of the drug's comparatively low potential for drug interactions, which is of importance in patient groups such as the elderly who are likely to receive more than one drug regimen.
	www.remedyfind.com /treatments/9/1431 (1557 words)

	Erowid Sertraline (Zoloft) Vault: Basics
		Sertraline is an SSRI (Selective Serotonin Reuptake Inhibitor) which changes the body's regulation of serotonin by blocking the reuptake of serotonin into 5HT neurons.
		Sertraline was introduced in 1986 as a treatment for depression and obsessive compulsive disorder.
		Anticonvulsants: sertraline may decrease the effectiveness of anticonvulsants and lower the seizure threshold.
	www.erowid.org /pharms/sertraline/sertraline_basics.shtml (215 words)

	N101 \| Sertraline (Site not responding. Last check: 2007-10-21)
		Sertraline is a member of the selective serotonin reuptake inhibitor (SSRI) family of drugs used to treat people with depression.
		The risk for SSRI-induced sodium depletion appears to be increased during the first few weeks of treatment in women, the elderly, and patients also using diuretics.
		In three men and two women treated with fluoxetine or sertraline (SSRI drugs closely related to paroxetine) for depression who experienced sexual dysfunction, addition of Ginkgo biloba extract (GBE) in the amount of 240 mg per day effectively reversed the sexual dysfunction.
	www.n101.com /Static/HNs/Drug/Sertraline.htm (1031 words)

	sertraline (Zoloft) - drug class, medical uses, medication side effects, and drug interactions by MedicineNet.com
		Sertraline was approved by the Food and Drug Administration in December, 1991.
		PRESCRIBED FOR: Sertraline is a drug that is used to treat depression, obsessive-compulsive disorder, panic disorder, and post-traumatic stress disorder.
		Cimetidine may increase the levels in blood of sertraline by reducing the elimination of sertraline by the liver.
	www.medicinenet.com /sertraline/article.htm (814 words)

	Sertraline, Zoloft Pharmacology - HealthyPlace.com (Site not responding. Last check: 2007-10-21)
		Renal Dysfunction: Sertraline is extensively metabolized and excretion of unchanged drug in the urine is a minor route of elimination.
		Pregnancy and Nursing: The safety of sertraline during pregnancy and nursing has not been established and therefore, it should not be used in women of childbearing potential or nursing mothers, unless, in the opinion of the physician, the potential benefits to the patient outweigh the possible hazards to the fetus.
		Sertraline should be administered with food once daily preferably with the evening meal, or, if administration in the morining is desired, with breakfast.
	www.healthyplace.com /medications/sertraline.htm (1425 words)

	ACS :: Cancer Drug Guide: sertraline hydrochloride
		Sertraline hydrochloride belongs to the general class of antidepressant drugs.
		Sertraline hydrochloride stops the uptake of serotonin by the nerves, thus making more serotonin available in the brain and central nervous system (CNS).
		Sertraline hydrochloride is a pill given by mouth once a day, either in the morning or evening.
	www.cancer.org /docroot/CDG/content/CDG_sertraline_hydrochloride.asp (556 words)

	Sertraline ( Zoloft ) data sheet
		Sertraline (Zoloft) is used in the treatment of all types of depression.
		Sertraline (Zoloft) works by helping to restore the balance of certain natural chemicals in the brain.
		Sertraline (Zoloft) has also been used to treat a severe form of premenstrual syndrome (premenstrual dysphoric disorder- PMDD) and a sexual function problem in men (premature ejaculation).
	psyweb.com /Drughtm/jsp/sertra.jsp (586 words)

	Zoloft - Drugs & Vitamins - Drug Library - DrugDigest
		Sertraline can also help people with an obsessive compulsive disorder, panic attacks, post-trauma stress, or social anxiety.
		Sertraline may also be prescribed for other purposes, like premenstrual dysphoric disorder (PMDD), a severe type of premenstrual syndrome.
		Sertraline has the potential to interact with a variety of medications, check with your healthcare professional.
	www.drugdigest.org /DD/DVH/Uses/0,3915,606\|Zoloft,00.html (863 words)

	Sertraline-Zoloft (Site not responding. Last check: 2007-10-21)
		Studies in animals also suggest that sertraline is a potent and selective inhibitor of neuronal serotonin reuptake and has only very weak effects on norepinephrine and dopamine neuronal reuptake.
		Previous research has shown sertraline to be effective in preventing relapse in patients suffering non-chronic episodes of major depression.
		Thirteen sertraline patients complained of sexual dysfunction compared to two individuals on placebo, a side effect commonly seen with antidepressant treatments.
	www.lorenbennett.org /sertra.htm (2160 words)

	Sertraline (Systemic) - MayoClinic.com (Site not responding. Last check: 2007-10-21)
		Sertraline has been tested in children 6 to 17 years of age with obsessive-compulsive disorder.
		Because sertraline may be given to different patients at different times of the day, you and your doctor should discuss what to do about any missed doses.
		Make sure you know how you react to sertraline before you drive, use machines, or do anything else that could be dangerous if you are not alert or well-coordinated.
	www.mayoclinic.com /health/drug-information/DR202651 (2427 words)

	Clinical Trial: A Study of Sertraline to Prevent PTSD
		The broad, long-term objectives of this proposal are to prevent the emergence of posttraumatic stress and depressive symptoms in children admitted for an acute burn, reconstructive surgery, or non-burn injury.
		It is comparing 60 subjects receiving sertraline with 30 placebo control subjects matched for age, severity of injury, and type of hospitalization (acute vs. reconstructive).
		While we have found no studies that have investigated the efficacy of sertraline in treating PTSD in children and adolescents, research indicates that sertraline is effective in treating other anxiety disorders and depression in children and adolescents.
	www.clinicaltrials.gov /ct/show/NCT00182078 (2334 words)

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