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	Lifespan's A - Z Health Information Library - Serum sickness
		Serum sickness is a group of symptoms caused by a delayed immune response to certain medications or antiserum (passive immunization with antibodies from an animal or another person).
		Serum sickness is a hypersensitivity reaction similar to an allergy.
		Serum sickness is different from anaphylactic shock, which is an immediate reaction with more severe symptoms.
	www.lifespan.org /adam/healthillustratedencyclopedia/1/000820.html (658 words)

	serum sickness - HighBeam Encyclopedia (Site not responding. Last check: 2007-11-06)
		serum sickness hypersensitive response that occurs after injection of a large amount of foreign protein.
		A person who has once had a serum injection is sensitized to the serum antigens, and a second injection can bring on the acute reactions typical of anaphylaxis.
		Endothelial selectins in acute mountain sickness and high-altitude pulmonary edema.
	www.encyclopedia.com /doc/1E1-serumsic.html (431 words)

	Serum sickness due to infliximab in a patient with psoriasis Journal of Drugs in Dermatology - Find Articles
		Serum sickness, which is an immune complex mediated syndrome consisting of a cutaneous eruption, fever, arthritis, edema, and lymphadenopathy, has been described in several patients receiving infliximab for the treatment of Crohn's disease.
		Serum sickness is a syndrome that is caused by the injection of a heterologous serum protein and results in an immune response which is mediated by immune complex deposition (11).
		However, most of the literature on the subject of serum sickness and serum sickness-like reactions appears to conform to the designations given by Buhner and Grant, who define serum sickness as the classic syndrome which occurs in response to an antigen that is derived from heterologous serum.
	www.findarticles.com /p/articles/mi_m0PDG/is_3_3/ai_n6056507/pg_8 (884 words)

	serum sickness (Site not responding. Last check: 2007-11-06)
		Serum sickness is usually an iatrogenous or iatrogenic (that is, produced by medical treatment) condition.
		In cases of serum sickness caused by antitoxin injection, the injection site where the antitoxin was given usually becomes red and swollen a few days before other symptoms begin.
		Plasma cleansing (plasmapheresis) is rarely used for severe serum sickness not responsive to the usual measures.
	www.drhull.com /EncyMaster/S/serum_sickness.html (269 words)

	Serum sickness
		Serum sickness is a type of delayed allergic response, appearing four to 10 days after exposure to some antibiotics or antiserum, the portion of serum that contains antibodies, such as gamma globulin, which may be given to provide immunization against some diseases.
		Although the symptoms of serum sickness may be similar to other conditions, patients who present with symptoms of serum sickness and who have a recent history of exposure to a drug or other product which may cause this type of reaction should be suspected of having serum sickness.
		Most serum sickness reactions are mild, and disappear on their own after one or two weeks as long as the cause is removed.
	www.healthatoz.com /healthatoz/Atoz/ency/serum_sickness.jsp (984 words)

	Serum Sickness: an immune complex reaction to foreign protein and drugs (Site not responding. Last check: 2007-11-06)
		Serum sickness is rare in humans, related to the decrease in usage of foreign serum proteins such as for treatment of snake or spider bite.
		Serum sickness is a relatively rare condition in humans, related to the decrease in usage of foreign serum proteins in treatment of human disease, such as for treatment of snake or spider bite.
		Whilst serum sickness if clearly an immunological reaction, it is not allergic in the strict definition of the word, since IgE antibodies are generally not produced.
	www.allergycapital.com.au /Pages/gpserum.html (335 words)

	Serum Sickness - New Treatments, January 2, 2007 (Site not responding. Last check: 2007-11-06)
		The serum sickness syndrome is a characteristic systemic immunologic disorder that follows the administration of a foreign material or medication.
		Serum sickness is the classic example of a type III hypersensitivity, "immune complex" disease.
		Antigen-antibody complexes formed under conditions of moderate antigen excess lodge in small vessels and in filtering organs throughout the body (deposition being aided in the rabbit by the actions of immunoglobulin [Ig] E antibody, basophils, and platelet-activating factor and by the release of vasoactive amines that increase the permeability of blood vessels); these complexes activate.
	www.ccspublishing.com /journals3a/serum_sickness.htm (247 words)

	Serum sickness (Site not responding. Last check: 2007-11-06)
		Serum sickness is an unusual reaction to any foreign substance in the body.
		Symptoms of serum sickness usually begin between 7 and 14 days after the person is exposed to the substance.
		Having an episode of serum sickness puts a person at high risk of developing a severe allergic reaction if he or she is exposed to the same substance in the future.
	www.webmd.com /hw/health_guide_atoz/sts14689.asp?printing=true (153 words)

	Serum Sickness
		Serum sickness results from a reaction to an antigen, a protein that the body recognizes as foreign.
		Serum sickness will usually develop within 7 to 10 days after initial exposure to the antigen; at times, however, the reaction does not develop until as long as three weeks later.
		Because of their potential to cause serum sickness, serum from animals should be avoided unless there is no other treatment option.
	www.umm.edu /altmed/ConsConditions/SerumSicknesscc.html (1299 words)

	Medical Dictionary: Serum sickness - WrongDiagnosis.com
		Serum sickness: a delayed allergic reaction to the injection of an antiserum caused by an antibody reaction to an antigen in the donor serum
		Serum sickness: immune complex disease caused by the administration of foreign serum or serum proteins and characterized by fever, lymphadenopathy, arthralgia, and urticaria; when they are complexed to protein carriers, some drugs can also cause serum sickness when they act as haptens inducing antibody responses.
		Serum sickness : immune complex disease caused by the administration of foreign serum or serum proteins and characterized by fever, lymphadenopathy, arthralgia, and urticaria; when they are complexed to protein carriers, some drugs can also cause serum sickness when they act as haptens inducing antibody responses.
	www.wrongdiagnosis.com /medical/serum_sickness.htm (360 words)

	Expert Advice -- Serum Sickness
		"Serum Sickness" reactions to antibiotics are thought to be due to a specific type of immune response (although the exact mechanism is somewhat controversial).
		In 1994, researchers figured out that while the reaction to cefaclor looks very similar to serum sickness, it is probably not caused by the same immune response mechanisms.
		While this finding does not affect the way the person with the reaction is treated (serum sickness and this reaction are treated the same way), it does mean that the person who has the reaction may not be at any greater risk for being allergic to other antibiotics.
	parenting.ivillage.com /tp/tphealth/0,,hf01,00.html (656 words)

	Serum sickness - WrongDiagnosis.com
		Immune complex disease caused by the administration of foreign serum or serum proteins and characterized by fever, lymphadenopathy, arthralgia, and urticaria; when they are complexed to protein carriers, some drugs can also cause serum sickness when they act as haptens inducing antibody responses.
		Serum sickness is a reaction to an antiserum derived from an animal source.
		Serum sickness typically develops up to ten days after exposure to the antiserum, and symptoms are similar to an allergic reaction.
	www.wrongdiagnosis.com /s/serum_sickness/intro.htm (509 words)

	eMedicine - Serum Sickness : Article by Susan M Chen, MD (Site not responding. Last check: 2007-11-06)
		Background: Serum sickness is a type III hypersensitivity reaction that results from the injection of heterologous or foreign protein or serum.
		When these were used, the incidences of serum sickness were 2-5% in patients receiving tetanus antitoxin and 16% in patients receiving rabies antitoxin.
		Prophylactic antihistamines may decrease the incidence of serum sickness by negating the action of vasoactive amines and preventing the increased vascular permeability that they induce.
	www.emedicine.com /emerg/topic526.htm (1899 words)

	Serum sickness associated with cefoxitin and pentoxifylline therapy -- Panwalker et al. 20 (12): 953 -- The Annals of ...
		Human serum sickness is a syndrome characterized by fever, malaise, skin rashes, arthralgias, gastrointestinal disturbances, and lymphadenopathy.
		We report the occurrence of serum sickness in a patient who received cefoxitin, a commonly used cephamycin antibiotic, and pentoxifylline, a xanthine derivative that improves the flow properties of blood by decreasing its viscosity.
		Serum sickness has not been previously reported with the use of cefoxitin or pentoxifylline.
	www.theannals.com /cgi/content/abstract/20/12/953 (157 words)

	Snake Bites: Bites and Stings: Merck Manual Home Edition
		Pit viper antivenom made from horse serum frequently causes serum sickness (an immune system reaction against foreign protein); newer antivenom made of purified antibody fragments from sheep is much safer.
		Serum sickness is a reaction by the immune system against large amounts of foreign protein that have entered the bloodstream.
		A common source of such foreign protein is horse serum, an ingredient found in many venom antidotes (antivenoms) that are used to treat poisonous snake and spider bites and scorpion stings.
	www.merck.com /mmhe/sec24/ch298/ch298d.html (922 words)

	Re: 1 dose of levaquin
		Serum Sickness is a condition in which the immune system binds with an element within the vaccine or antibiotic to form what are known as "immune complexes." These immune complexes then mistake healthy tissue for foreign invaders, and thus attack the body.
		Serums Sickness usually develops within 7 to 21 days after taking the medication.
		> Serum Sickness is a condition in which the > immune system binds with an element within > the vaccine or antibiotic to form what are > known as "immune complexes." These > immune complexes then mistake healthy tissue > for foreign invaders, and thus attack the > body.
	www.rxlist.com /rxboard/levaquin.pl?read=1069 (1263 words)

	Allergy & Asthma Disease Management Center: Ask the Expert: Serum Sickness
		Your description sounds like an atypical serum sickness reaction to me. Although serum sickness reactions typically start 7-10 days after the stimulus, it is conceivable that your wife's prior insect stings may have altered her immune responses to insect stings so that she started reacting a bit sooner.
		A mac-papular rash is not the typical skin manifestation of serum sickness (most commonly urticaria/angioedema).
		However, at the end of the hospitalization, a diagnosis of probable serum sickness was made.
	www.aaaai.org /aadmc/ate/serumsickness.html (789 words)

	eMedicine - Serum Sickness : Article by Hassan M Alissa, MD
		Serum cryoglobulins, which in effect are circulating immune complexes in vivo, may be present in some patients with serum sickness.
		Secondary serum sickness is the result of antigen recognition by presensitized cells of the immune system, and this disorder is characterized by a shorter latent period, exaggerated symptoms, and a brief clinical course.
		In a recent clinical trial to evaluate the efficacy and safety of recombinant murine monoclonal antibody to human tumor necrosis factor alpha in patients with sepsis, serum sickness reactions were noted in 15 (2.3%) of 645 patients in the treatment group.
	www.emedicine.com /med/topic2105.htm (2071 words)

	Serum sickness - serum sickness antibiotic rocephin
		Serum serum sickness antibiotic rocephin sickness serum sickness antibiotics is a reaction to an treatments for serum sickness antiserum derived from an animal source.
		When the antiserum is given, the human immune system can mistake the proteins present for serum sickness harmful antigens.
		Symptoms will generally disappear on igiv and serum sickness their own, although corticosteroids serum sickness and horses may be prescribed in the most severe serum sickness due to bee sting forms.
	www.medicalgeo.com /Med-Diseases-R---Se/Serum-sickness.html (289 words)

	Serum sickness
		Serum sickness can be developed as a result of exposure to antibodies derived from animals.
		These serums are generally administered in order to prevent infection.
		Serum sickness can also be caused by several drugs, notably penicillin based medicines.
	www.mrsci.com /Immunology/Serum_sickness.php (191 words)

	Healthopedia.com - Serum Sickness
		Serum is the fluid left over when blood cells are taken out of the blood.
		Serum sickness refers to a set of symptoms that occurs when a person's immune system reacts to a medication or other similar substance.
		A person with serum sickness has an immune system reaction after taking a medication or similar substance.
	www.healthopedia.com /serum-sickness (341 words)

	Serum sickness-like reaction to pamabrom Journal of Drugs in Dermatology - Find Articles
		Serum sickness-like reactions (SSLR) are characterized by fever, cutaneous eruptions and arthralgias, with or without lymphadenopathy and eosinophilia, usually developing within a few weeks of drug initiation.
		In 1905, von Pirquet first described serum sickness when patients who received injections of equine diphtheria antitoxin developed fever, cutaneous eruptions, arthralgias, gastrointestinal symptoms, lymphadenopathy, and proteinuria.
		Serum sickness-like reaction in our patient was unusual in that it was associated with proteinuria, a common finding in a serum sickness reaction.
	www.findarticles.com /p/articles/mi_m0PDG/is_3_5/ai_n16120900 (763 words)

	BioMed Central \| Full text \| Serum sickness-like reaction associated with cefazolin
		Serum complement levels, immunoglobulin concentrations, and erythrocyte sedimentations rate were not obtained at this time.
		Serum sickness-like reactions have been noted to occur in response to a variety of drugs, a majority of them being antibiotics[5].
		Accordingly, the levels of circulating immune complexes and serum complement are often unaffected[5].
	www.biomedcentral.com /1472-6904/6/3 (1334 words)

	Canadian Adverse Drug Reation Newsletter-Volume 6, Number 4, October 1996
		Serum sickness was first described by von Pirquet in 1905 following the use of antidiptheria horse serum.
		In contrast to classic serum sickness, signs and symptoms of SSLR involving cefaclor appear to be confined primarily to findings including erythema multiforme or other skin manifestations accompanied by arthritis or arthralgia, with or without fever.
		Furthermore, knowledge of the family's drug history may be pertinent as one study suggests cefaclor-associated SSLR may result from inherited defects in the metabolism of reactive intermediates.
	www.hc-sc.gc.ca /dhp-mps/medeff/bulletin/carn-bcei_v6n4_e.html (1117 words)

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