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| | Interactive Fly, Drosophila |
 | | Zeste-white 3, also known as Shaggy, is one of crucial kinases in the cell, and a critical one at that. |
 | | Thus Shaggy is between the Dishevelled and Armadillo in the signal transduction pathway, receiving signals from Dishevelled and modifying Armadillo's association with junctions and its signaling process to the nucleus. |
 | | This second role of shaggy, now virtually ignored because of the current preoccupation with the function of Suppressor of hairless, may be due to modulation of some component of the Notch pathway (Simpson, 1993). |
| www.sdbonline.org /fly/segment/shaggy.htm (1227 words) |
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