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Topic: Sickle-cell disease

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Sickle Cell Disease - Children's Hospital of Philadelphia Sickle cell disease is a group of inherited blood disorders in which the main hemoglobin (a protein in red blood cells that carries oxygen to the tissues of the body) is defective. Sickle cell is an inherited disease caused by a genetic mutation. For a child to have a form of sickle cell disease, he or she must inherit at least one sickle gene from one parent and either a sickle gene or another abnormal hemoglobin gene from the other parent. www.chop.edu /consumer/your_child/condition_section_index.jsp?id=-8808   (2180 words)

Sickle Cell Disease Symptoms of sickle cell disease vary and range from mild to severe, and symptoms may be less severe or different in children who have inherited a sickle cell gene from one parent and a different abnormal hemoglobin gene from the other. Sickle cell disease is an inherited disorder of the red blood cells characterized by abnormally shaped red cells. People with sickle cell trait don't have sickle cell disease or exhibit any signs of the disorder, but they can pass the gene for the disease to their children. kidshealth.org /parent/medical/heart/sickle_cell_anemia.html   (1446 words)

Sickle Cell Disease -- Buchanan et al. 2004 (1): 35 -- Hematology subphenotypes of sickle cell disease and intervening to forestall Sustained induction of fetal hemoglobin by pulse butyrate therapy in sickle cell disease. Risk of recurrent stroke in children with sickle cell disease receiving blood transfusion therapy for at least five years after initial stroke. www.asheducationbook.org /cgi/content/full/2004/1/35   (6409 words)

What is Sickle Cell Disease Sickle Cell trait (AS) is an inherited condition in which both hemoglobin A and S are produced in the red blood cells, always more A than S. Sickle cell trait is not a type of sickle cell disease. Sickle cells are destroyed rapidly in the body of people with the disease causing anemia, jaundice and the formation of gallstones. Sickle cell conditions are inherited from parents in much the same way as blood type, hair color and texture, eye color and other physical traits. www.sicklecelldisease.org /about_scd/index.phtml   (924 words)

Berkeley Scientists Develop Mouse Model For Sickle Cell Research Sickle cell disease was once referred to as sickle cell anemia but the term"anemia" was dropped because it emphasized only one manifestation of the condition. Development of the sickle cell mouse was funded by grants from the National Heart, Lung, and Blood Institute, and the National Institute for Diabetes, Digestive, and Kidney Diseases, and in part, by the Office of Biological and Environmental Research in the U.S. Department of Energy. In contrast to the limited studies that can be performed in humans, Paszty and Rubin say these animals provide an opportunity for rapidly performing a wide range of experiments, and should play an important role in furthering our understanding of sickle cell disease and in developing improved therapies for treating sickle cell patients." www.lbl.gov /Science-Articles/Archive/sickle-cell-mouse.html   (861 words)

Sickle Cell Disease Sickle cell disease, a group of blood disorders, is inherited, passed from parent to child. These children don't have sickle cell disease but are carriers of the defective gene and may pass it on to their children. Consultation with doctors skilled in the care of patients with sickle cell disease. www.peacehealth.org /kbase/topic/major/hw254173/descrip.htm   (445 words)

WHAT IS SICKLE CELL DISEASE? Even though we often see the term sickle cell anemia used to refer to all types of sickle cell disease, technically, SS disease is the only form of sickle cell disease that is correctly referred to as sickle cell anemia. As sickle cell is a genetic disorder, in order to have sickle cell disease, you must inherit a hemoglobin S gene. The red blood cells of people with sickle cell disease contain an abnormal type of hemoglobin, the oxygen-carrying pigment, called hemoglobin S. The deficiency of oxygen in the blood causes hemoglobin S to crystallize, distorting the red blood cells into a sickle shape, making them fragile and easily destroyed, leading to anemia. www.defiers.com /scd.html   (1102 words)

What is Sickle Cell Anaemia? This means that this person has enough normal haemoglobin in their red blood cells to keep the cells flexible and they don't have the symptoms of the sickle cell disorders. When a person is found to have a sickle cell disorder it is important that all members of the family be tested. Sickle Cell Disorder is a condition which is inherited from both parents. www.sicklecellsociety.org /education/sicklecell.htm   (853 words)

Sickle Cell Disease: Information for School Personnel The first edition Sickle Cell Disease: Management for the School Nurse was prepared by the Child Health Promotion, Pediatric Preventive Services, Health Promotion/Disease Prevention Services Unit and was adapted from Sickle Cell Disease: A Family Guide, New Jersey State Department of Health, 1993. Sickle Cell Disease: Information for School Personnel Trenton, NJ: Special Child, Adult and Early Intervention Services, New Jersey Department of Health and Senior Services, September 1999. This second edition was revised and edited by Richard A. Drachtman, M.D., Division of Pediatric Hematology/Oncology, University of Medicine and Dentistry of New Jersey/Robert Wood Johnson Medical School, in collaboration with the Sickle Cell Advisory Committee in New Jersey and the NJ Department of Health and Senior Services. www.state.nj.us /health/fhs/sicklecell   (249 words)

Your Health: Trover Foundation Sickle cell disease is a heredity disorder that occurs when a person gets a defective gene for hemoglobin from both parents. It is similar to pneumonia and is caused by sickle cells trapped in the lungs. NHLBI says the sickle cell gene is the result of a mutation thousands of years ago in parts of Africa, the Mediterranean basin, the Middle East and India. www.stayinginshape.com /4troverfoundation/libv/i50.shtml   (972 words)

Problems with Sickle Cell Anaemia Sickle beta thalassemia is a less common form of sickle cell disease. Sickle cells tend to become trapped and destroyed in the liver and in the spleen. Some affected people rarely see their doctors for sickle cell-related complaints; others may be hospitalised frequently. village.vossnet.co.uk /g/gilbert/mysickle.htm   (337 words)

Sickle Cell Individuals with sickle cell disease have a life-expectancy of almost 40 years, and physicians expect that to be much higher in the next decade due to recent advances medical care. People with sickle cell disease generally receive treatment in two ways: They get medicines or blood transfusions when they are having problems; they also receive medicines or blood transfusions to keep these problems from happening again. Most people with sickle cell disease have pain at times. www.redcrossalabama.org /sickle1.htm   (543 words)

Sickle cell anemia - MayoClinic.com Sickle cell anemia is an inherited form of anemia — a condition in which there aren't enough healthy red blood cells to carry oxygen throughout your body. In people with sickle cell anemia, the red blood cells become rigid and sticky and are shaped like sickles or crescent moons. There's no cure for most people with sickle cell anemia. www.mayoclinic.com /health/sickle-cell-anemia/DS00324   (248 words)

Sickle Cell Disease Sickle cell disease is estimated to affect more than 72,000 Americans and has been identified in persons from several different racial backgrounds. A sickle cell patient need not be a U.S. citizen to qualify if he/she is treated for sickle cell disease in the U.S. The Reimbursement Assistance Program helps sickle cell patients recover financial reimbursement or establish coverage for hydroxurea from their health insurance providers. Sickle cell disease refers to a group of genetic disorders characterized by the presence of sickle hemoglobin (Hb S). www.in.gov /isdh/programs/owh/action/sickle_cell_disease.htm   (1011 words)

Sickle-Cell Disease The damage and durability of sickle-cell disease occurs because the logjam that sickle cells cause in the capillaries slows the flow of blood and reduces the supply of oxygen to various tissues. Fortunately, with screening tests for sickle cell now required for newborns in most states and with the use of preventive antibiotics in babies who are born with the disease, this terrible mortality rate has dropped significantly. Sickle cells disease is a result of changes in hemoglobin S: The destructive nature of the sickle hemoglobin develops when it loses oxygen. www.morehead.org /wellconnected/000058.htm   (12050 words)

The Sickle Cell Disease Program at St. Louis Children’s Hospital. Similar to other children with chronic illness, children with sickle cell disease are at increased risk for school absenteeism related to their illness, but unlike most other children with chronic illness, children with sickle cell disease have a high frequency of strokes. The cornerstone of improving the quality of life for children with sickle cell disease and their parents is education about their disease. To increase the school potential of children with sickle cell disease the division has formed a partnership between the parents, teachers and students through the development of the Stay In School Program. www.stlouischildrens.org /articles/kids_parents.asp?ID=247   (791 words)

Sickle Cell Disease The Sickle Cell Foundation of Alberta is a private non-profit organization founded to help educate the public about sickle cell disease and provide support for carriers of the trait and their families. The Sickle Cell Disease Association of America is a national membership organization that provides education, research updates, support, screening services and counseling. The foundation aims to provide quality education and promote public professional awareness about sickle cell disease. www.bchealthguide.org /kbase/topic/major/hw254173/conres.htm   (202 words)

eMedicine - Pediatrics, Sickle Cell Disease : Article by Nedra Dodds, MD The patient with sickle cell disease is susceptible to a multitude of complications during this life-long disease. Penicillin prophylaxis for encapsulated organisms is instituted as soon as the diagnosis of sickle cell disease is established, preferably by the age of 2 months. History: Patients with sickle cell disease, at some point in their lifetime, may experience exacerbations in their clinical course. www.emedicine.com /emerg/topic406.htm   (4624 words)

Sickle Cell Disease Sickle cell disease refers to a group of genetic disorders. Overall treatments for sickle cell disease, including medications, photocoagulation and basic optometric care, are discussed along with differential diagnosis. Sickle Cell Disease: A Behavioral Approach to a Systemic Disease www.oep.org /green14-1.htm   (154 words)

Sickle Cell Disease / Family Village Sickle Cell Disease Association of America, Inc. is helping to promote finding a universal cure for sickle cell disease, and helping to improve the quality of life for individuals and families where sickle cell disease related conditions exist. The Sickle Cell Disease Association of America, Inc. (SCDAA), formerly know as the National Association for Sickle Cell Disease (NASCD) was founded in 1971 to provide an effective coordinated community-based approach to developing and implementing strategies to resolve issues surrounding sickle cell disease. The organization currently provides a wide range of services to those individuals and families with either sickle cell anemia, sickle cell trait, or variants of the disease. www.familyvillage.wisc.edu /lib_scd.htm   (268 words)

Clinical Trial: Home Based Massage and Relaxation for Sickle Cell Pain Diagnosis of disease in addition to sickle cell disease which requires regular use of pain medication. Sickle cell trait instead of sickle cell disease diagnosis. Thomas JE, Koshy M, Patterson L, Dorn L, Thomas K. Management of pain in sickle cell disease using biofeedback therapy: a preliminary study. www.clinicaltrials.gov /show/NCT00066079   (530 words)

Hardin MD : Sickle Cell Anemia Last updated Tuesday, Nov 29, 2005 [sickle cell pictures, pictures of sickle cell anemia, information on sickle cell anemia, sickle cell disease pictures, sickle cell disease anemia, sickle cell anemia symptoms, sickle cell anemia symtoms, sickle cell anemia symptons, sickle cell animia, sickel cell anemia, sickel cell anemia, pictures on sickle cell disease] [95214 Sickle cell disease (Click links in right margin for more pictures) Sickle cell anemia (Includes pictures from some sites on this page) www.lib.uiowa.edu /hardin/md/sicklecellanemia.html   (147 words)

Sickle Cell Disease Transition of Patients with Sickle Cell Disease from Pediatric to Adult Care Care Coordination for Patients with Sickle Cell Disease Development of a Comprehensive Care Program for Patients with Sickle Cell Disease sickle.bwh.harvard.edu /menu_sickle.html   (44 words)

Sickle Cell Information Center Home Page It is the mission of our organizations to provide world class compassionate care, education, counseling, and research for patients with sickle cell disease. The mission of this site is to provide sickle cell patient and professional education, news, research updates and world wide sickle cell resources. It is our mission to help break the sickle cycle. www.scinfo.org   (205 words)

Sickle Cell Disease: What is it? Concept 15: DNA and proteins are key molecules of the cell nucleus. Learn the basic chemistry of DNA and proteins. www.ygyh.org /sickle/whatisit.htm   (28 words)

Sickle Cell Disease Association of America -- SCDAA Home The U.S. Postal Service unveiled the Sickle Cell Disease Awareness Commemorative stamp on Thursday evening, Sept. 25, at the 31st annual convention of Sickle Cell Disease Association of America Inc.. Copyright © 2005 Sickle Cell Disease Association of America, Inc. Sickle Cell Disease Association of America -- SCDAA Home www.sicklecelldisease.org   (127 words)

How Does Sickle Cell Cause Disease? Sickle cell disease is a blood condition seen most commonly in people of African ancestry and in the tribal peoples of India. Therefore, the inheritance of sickle cell disease depends totally on the genes of the parents. Sickle cell disease is determined at conception, when a person acquires his/her genes from the parents. sickle.bwh.harvard.edu /scd_background.html   (127 words)

How Does Sickle Cell Cause Disease? Sickle cell disease is a blood condition seen most commonly in people of African ancestry and in the tribal peoples of India. Therefore, the inheritance of sickle cell disease depends totally on the genes of the parents. Sickle cell disease is determined at conception, when a person acquires his/her genes from the parents. sickle.bwh.harvard.edu /scd_background.html   (127 words)

Sickle Cell Anemia sickle cell disease sickle cell disease or sickle cell anemia,inherited disorder of the blood in which the oxygen-carrying hemoglobin pigment in erythrocytes (red blood cells) is abnormal. If you and your partner both have sickle cell trait there is a 25% chance of the child having normal hemoglobin, a 50% chance of the child having the sickle cell trait, and a 25% of having sickle cell disease. Sickle Cell Disease: When an individual has only hemoglobin S and no hemoglobin A, then he or she has sickle cell disease. www.uni.edu /darrow/frames/bio/sickle.html   (127 words)

What Is Sickle Cell Anemia? Sickle cell anemia is an inherited blood disease. Sickle cell anemia is a serious disease and there is no universal cure. DCI Home : Blood Diseases : Sickle Cell Anemia : What Is... www.nhlbi.nih.gov /health/dci/Diseases/Sca/SCA_WhatIs.html   (127 words)

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