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Topic: Siderophore

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	Biosynthesis and Uptake of Siderophores Is Controlled by the PacC-Mediated Ambient-pH Regulatory System in Aspergillus ...
		of synthesis and uptake of siderophores by iron is mediated
		to siderophore biosynthesis, uptake of native and heterologous
		Haas, H. Molecular genetics of fungal siderophore biosynthesis and uptake: the role of siderophores in iron uptake and storage.
	ec.asm.org /cgi/content/full/3/2/561 (1828 words)

	DYNAMISM OF SIDEROPHOREGENIC BRADYRHIZOBIA IN SOYBEAN YIELD IMPROVEMENT
		This indicates the presence of hydroxamate siderophores in aqueous layer with absorption maxima at 216 nm.
		Siderophore production was monitored during growth under iron limited conditions in a medium containing, 0-100 m M extraneous iron (Fig.5).
		It was observed that the siderophore showing maximum absorption at 216 nm and which was identified as citrate was decreased as per increase in iron concentration.
	www.osmania.ac.in /MicroBiology/2p04.htm (1268 words)

	Siderophore Mediated Iron Bioavability--Research--Crumbliss Group Home Page--Duke University
		To investigate molecular mechanisms for siderophore mediated Fe acquisition, transport, and storage by microbes.
		Our approach includes spectroscopic, kinetic and thermodynamic studies of Fe-siderophore and model siderophore complexes, molecular recognition, and membrane transport.
		"Chemical Aspects of Siderophore Mediated Iron Transport" H. Boukhalfa and A. Crumbliss, BioMetals, 15, 325 (2002).
	www.chem.duke.edu /~alc/labgroup/siderophore.htm (74 words)

	SIDEROPHORE PRODUCTION BY MARINE HETEROTROPHIC BACTERIA (Site not responding. Last check: 2007-10-25)
		Recent research has shown that most of the iron in seawater is complexed by organic ligands, a condition that may affect the availability of iron to the biota.
		Siderophores from marine bacteria could contribute to the iron ligand pool.
		We investigated strains that are as closely related as possible to sequences that appear in molecular surveys, and strains from groups whose siderophores have not been previously studied.
	aslo.org /santafe99/abstracts/SS28WE0469S.html (196 words)

	Siderophore - Wikipedia, the free encyclopedia
		A Siderophore (greek for iron carrier) is an iron chelating compound secreted by microorganisms.
		Examples of siderophores produced by various bacteria and fungi are ferrichrome (Ustilago sphaerogena), enterobactin (Escherichia coli), enterobactin and bacillibactin (Bacillus subtilis), ferrioxamine B (Streptomyces pilosus), fusarinine C (Fusarium roseum), yersiniabactin (Yersinia pestis), vibriobactin (Vibrio cholerae), azotobactin (Azotobacter vinelandii), pseudobactin (Pseudomonas B 10) or erythrobactin (Saccharopolyspora erythraea).
		This page was last modified 14:43, 22 May 2006.
	en.wikipedia.org /wiki/Siderophore (143 words)

	Ralstonia solanacearum Iron Scavenging by the Siderophore Staphyloferrin B Is Controlled by PhcA, the Global Virulence ...
		a siderophore in the genome of Staphylococcus aureus MW2 and
		Purification of catechol siderophores by boronate affinity chromatography: identification of chrysobactin from Erwinia carotovora subsp carotovora.
		Export of the siderophore enterobactin in Escherichia coli: involvement of a 43 kDa membrane exporter.
	jb.asm.org /cgi/content/full/186/23/7896 (5141 words)

	Characterization of Fluorescent and Nonfluorescent Peptide Siderophores Produced by Pseudomonas syringae Strains and ...
		in the fluorescent siderophore and a dihydropyoverdin chromophore
		of the nonfluorescent siderophore in the cognate fluorescent one.
		Bacterial siderophores: the structures of the pyoverdins of Pseudomonas fluorescens ATCC 13525.
	aem.asm.org /cgi/content/full/67/4/1718 (5045 words)

	Acquisition, Transport, and Storage of Iron by Pathogenic Fungi -- Howard 12 (3): 394 -- Clinical Microbiology Reviews
		are a high-affinity ferric iron reductase and siderophore synthesis.
		Isolation and identification of the principal siderophore of the dermatophyte Microsporum gypseum.
		Identification of siderophores and siderophore-mediated uptake of iron in Stemphylium botryosum.
	cmr.asm.org /cgi/content/full/12/3/394 (6725 words)

	Identification and analysis of a siderophore biosynthetic gene cluster from Agrobacterium tumefaciens C58 -- Rondon et ...
		that encodes the biosynthesis of a metabolite with siderophore
		The arrow identifies the metabolite peak at 16·4 min from the wild-type strain that was associated with siderophore activity.
		Challis, G. and Ravel, J. Coelichelin, a new peptide siderophore encoded by the Streptomyces coelicolor genome: structure prediction from the sequence of its non-ribosomal peptide synthetase.
	mic.sgmjournals.org /cgi/content/full/150/11/3857 (4986 words)

	Identification of a Candida albicans Ferrichrome Transporter and Its Characterization by Expression in Saccharomyces ...
		Siderophore Plate Growth-- The siderophores ferrioxamine B (FOB) (Desferal®), ferrichrome (Fc), and rhodotorulic acid were obtained from Sigma.
		Cells were harvested and siderophore iron uptake assayed as described under "Experimental Procedures." Data are expressed using the Lineweaver-Burke analysis.
		siderophore is bound to the surface of the transporter, as opposed
	www.jbc.org /cgi/content/full/276/46/43049 (3259 words)

	Bacterial Growth Stimulation with Exogenous Siderophore and Synthetic N-Acyl Homoserine Lactone Autoinducers under ...
		To confirm the cooperative influences of the exogenous siderophore and HSL on the growth of V0110 in the liquid medium, V0110
		To estimate whether the effect of the exogenous siderophore and the HSL autoinducer is a specific activity of V0110 or is
		A siderophore from a marine bacterium with an exceptional ferric iron affinity constant.
	aem.asm.org /cgi/content/full/66/7/2797 (3700 words)

	Discovery of a Nonclassical Siderophore, Legiobactin, Produced by Strains of Legionella pneumophila -- Liles et al. 182 ...
		siderophore is not a typical catecholate or hydroxamate.
		Cloning, mutagenesis and nucleotide sequence of a siderophore biosynthetic gene (amoA) from Aeromonas hydrophila.
		Identification and characterization of iron-regulated Bordetella pertussis alcaligin siderophore biosynthesis genes.
	jb.asm.org /cgi/content/full/182/3/749 (5906 words)

	Analysis of a DtxR-Regulated Iron Transport and Siderophore Biosynthesis Gene Cluster in Corynebacterium diphtheriae -- ...
		the siderophore is proposed to be a lipoprotein that is anchored
		Corynebactin, a cyclic catecholate siderophore from Corynebacterium glutamicum ATCC 14067 (Brevibacterum sp.
		Iron-dependent regulation of diphtheria toxin and siderophore expression by the cloned Corynebacterium diphtheriae repressor gene dtxR in C.
	jb.asm.org /cgi/content/full/187/2/422 (7567 words)

	Genetic organization of an Acinetobacter baumannii chromosomal region harbouring genes related to siderophore ...
		Massad, G., Arceneaux, J. and Byers, B. Diversity of siderophore genes encoding biosynthesis of 2,3-dihydroxybenzoic acid in Aeromonas spp.
		Neilands, J. Siderophores: structure and function of microbial iron transport compounds.
		Rusnak, F., Sakaitani, M., Drueckhammer, D., Reichert, J. and Walsh, C. Biosynthesis of the Escherichia coli siderophore enterobactin: sequence of the entF gene, expression and purification of EntF, and analysis of covalent phosphopantetheine.
	mic.sgmjournals.org /cgi/content/full/149/5/1227 (5827 words)

	Siderophore uptake and use by the yeast Saccharomyces cerevisiae -- Lesuisse et al. 147 (2): 289 -- Microbiology
		Siderophore uptake and use by the yeast Saccharomyces cerevisiae -- Lesuisse et al.
		); the assumption that siderophore uptake is non-reductive
		Heymann, P., Ernst, J. and Winkelmann, G. Identification of a fungal triacetylfusarinine C siderophore transport gene (TAF1) in Saccharomyces cerevisiae as a member of the major facilitator superfamily.
	mic.sgmjournals.org /cgi/content/full/147/2/289 (4434 words)

	Role of Siderophore Biosynthesis in Virulence of Staphylococcus aureus: Identification and Characterization of Genes ...
		Siderophore levels in spent culture supernatants of RN6390 and Newman and their respective fur derivatives, H295 and H706.
		Siderophore units were calculated as described in Materials and Methods.
		Isolation and characterization of staphyloferrin A, a compound with siderophore activity from Staphylococcus hyicus DSM 20459.
	iai.asm.org /cgi/content/full/72/1/29 (4943 words)

	Endocytic delivery of lipocalin-siderophore-iron complex rescues the kidney from ischemia-reperfusion injury -- Mori et ...
		The second panel shows that apo-Ngal from BL21 bacteria (siderophore free) was minimally active, but that, when loaded with a siderophore (enterochelin), the protein was protective: both iron-free (apo-Ngal:Sid) and iron-loaded siderophores (apo-Ngal:Sid:Fe) had a protective effect.
		In comparison, the gallium-loaded complex (apo-Ngal:Sid:gallium) was ineffective, as was a single dose of the iron chelator DFO or the free siderophore (Sid).
		the bacterial siderophore was extractable in ethyl acetate,
	www.jci.org /cgi/content/full/115/3/610 (7991 words)

	Microbial iron transport via a siderophore shuttle: A membrane ion transport paradigm -- Stintzi et al. 97 (20): 10691 ...
		(Left) The usual siderophore iron delivery mechanism: a, ferric siderophore is bound to the protein receptor, causing a conformational change in the protein; b, the ferric siderophore is pumped through the receptor into the periplasmic space; and c, on release of the ferric siderophore, the receptor protein returns to its original conformation.
		siderophores coprogen, rhodotorulic acid, or ferrioxamine B (18).
		The ability of 20 heterologous siderophores and siderophore analogs to mediate iron transport in A.
	www.pnas.org /cgi/content/full/97/20/10691 (4131 words)

	Siderophore Biosynthesis But Not Reductive Iron Assimilation (Site not responding. Last check: 2007-10-25)
		Siderophore Biosynthesis But Not Reductive Iron Assimilation Is Essential for Aspergillus fumigatus Virulence
		In striking contrast, A. fumigatus L-ornithine-N 5-monooxygenase (SidA), which catalyses the first committed step of hydroxamate-type siderophore biosynthesis, is absolutely essential for virulence.
		Combined with the absence of a sidA ortholog—and the fungal siderophore system in general—in mammals, these data demonstrate that the siderophore biosynthetic pathway represents a promising new target for the development of antifungal therapies.
	www.mold-survivor.com /siderophore_biosynthesis_but_not.html (211 words)

	Genetics and Assembly Line Enzymology of Siderophore Biosynthesis in Bacteria -- Crosa and Walsh 66 (2): 223 -- ...
		(PPTase) is encoded in the siderophore biosynthetic gene cluster
		of the siderophore pyochelin and its precursors salicylate and
		it is a receptor of the siderophore and a receptor of Y.
	mmbr.asm.org /cgi/content/full/66/2/223 (8605 words)

	Siderophore-Mediated Iron Transport: Crystal Structure of FhuA with Bound Lipopolysaccharide -- Ferguson et al. 282 ... (Site not responding. Last check: 2007-10-25)
		by the siderophore moiety, thereby ensuring transport of the conjugate
		Siderophore Transport through Escherichia coli Outer Membrane Receptor FhuA with Disulfide-tethered Cork and Barrel Domains.
		Dimerization of TonB Is Not Essential for Its Binding to the Outer Membrane Siderophore Receptor FhuA of Escherichia coli.
	www.sciencemag.org /cgi/content/full/282/5397/2215 (5712 words)

	The Siderophore Iron Transporter of Candida albicans (Sit1p/Arn1p) Mediates Uptake of Ferrichrome-Type Siderophores and ...
		The Siderophore Iron Transporter of Candida albicans (Sit1p/Arn1p) Mediates Uptake of Ferrichrome-Type Siderophores and Is Required for Epithelial Invasion -- Heymann et al.
		The concentrations of siderophores and other compounds are listed in Table 2.
		Siderophore uptake by Candida albicans: effect of serum treatment and comparison with Saccharomyces cerevisiae.
	iai.asm.org /cgi/content/full/70/9/5246 (5483 words)

	Detection and Analysis of Iron Uptake Components Expressed by Acinetobacter baumannii Clinical Isolates -- Dorsey et ...
		of this siderophore in a pathway that may be similar to that
		Detection of siderophore activity and catechol compounds produced under iron-rich and iron-limiting conditions.
		Isolation and structure elucidation of acinetobactin, a novel siderophore from Acinetobacter baumannii.
	jcm.asm.org /cgi/content/full/41/9/4188 (3582 words)

	ARS \| Publication request: Identification of a Siderophore Biosynthetic Gene from the Fish Pathogen Aeromonas ...
		To identify the genes involved in siderophore synthesis and utilization in A. salmonicida, mutants were generated using the mini-transposon mini-Tn5K, and screened for defects in the production of siderophore activity on chromazurol S agar (CAS agar).
		One such mutant, designated AStn-11, grew poorly and overproduced siderophore activity when grown on CAS agar, this phenotype is likely due to the insertion occurring in a transport gene.
		By thin layer chromatography we confirmed that multiple siderophores are produced by this strain and showed that the salF gene is essential for the production of one of the siderophores produced.
	www.ars.usda.gov /research/publications/publications.htm?seq_no_115=150247&pf=1 (296 words)

	Sloan-Kettering - Projects: Siderophore Biosynthesis Inhibitors
		One specialized mechanism of iron uptake involves the biosynthesis of siderophores, non-ribosomal peptide/polyketide natural products with extremely high affinity for Fe Bacteria export these siderophores into the medium of the mammalian host, where they capture iron from mammalian proteins.
		The siderophores are then actively transported back into the bacterial cells.
		Small molecules that block siderophore biosynthesis and, hence, iron uptake are attractive targets for the development of new antibiotics to treat multidrug resistant infections.
	www.mskcc.org /mskcc/html/54047.cfm (164 words)

	Title page for ETD etd-04182003-134826
		The forces of interaction were measured between the siderophore azotobactin and the minerals goethite (FeOOH) and diaspore (AlOOH) in solution using force microscopy.
		Ab initio calculations on siderophore fragment analogs suggest the iron affinity can be attributed to increased electron density associated with the Fe-O bond compared to the Al-O bond; an observation that correlates with iron’s larger electronegativity compared to aluminum.
		Attachment of the ligand to each surface was directed by steric forces within the molecule and coulombic interactions between the siderophore oxygens and the metals in the mineral.
	scholar.lib.vt.edu /theses/available/etd-04182003-134826 (376 words)

	Genome-Wide Screen for Genes With Effects on Distinct Iron Uptake Activities in Saccharomyces cerevisiae -- Lesuisse et ...
		The siderophore pathway mediates iron uptake from siderophores
		Both siderophore and reductive pathways for iron uptake are
		, H., 2003 Molecular genetics of fungal siderophore biosynthesis and uptake: the role of siderophores in iron uptake and storage.
	www.genetics.org /cgi/content/full/169/1/107 (6679 words)

	Survey of Ferroxidase Expression and Siderophore Production in Clinical Isolates of Pseudomonas aeruginosa -- Huston et ...
		Centre for Metals in Biology, Department of Microbiology and Parasitology, School of Molecular and Microbial Sciences, University of Queensland, St Lucia, 4072 Queensland, Australia,
		for the presence of the MCO protein and siderophores.
		Universal chemical assay for the detection and determination of siderophores.
	jcm.asm.org /cgi/content/full/42/6/2806 (1708 words)

	Genetics and Assembly Line Enzymology of Siderophore Biosynthesis in Bacteria -- Crosa and Walsh 66 (2): 223 -- ...
		Alice, A. F., Lopez, C. S., Crosa, J. Plasmid- and Chromosome-Encoded Redundant and Specific Functions Are Involved in Biosynthesis of the Siderophore Anguibactin in Vibrio anguillarum 775: a Case of Chance and Necessity?.
		O Cuiv, P., Clarke, P., Lynch, D., O'Connell, M. Identification of rhtX and fptX, Novel Genes Encoding Proteins That Show Homology and Function in the Utilization of the Siderophores Rhizobactin 1021 by Sinorhizobium meliloti and Pyochelin by Pseudomonas aeruginosa, Respectively.
		Kunkle, C. A., Schmitt, M. Analysis of the Corynebacterium diphtheriae DtxR Regulon: Identification of a Putative Siderophore Synthesis and Transport System That Is Similar to the Yersinia High-Pathogenicity Island-Encoded Yersiniabactin Synthesis and Uptake System.
	mmbr.asm.org /cgi/content/abstract/66/2/223 (1397 words)

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