
	Where results make sense

Topic: Signal sequence

Related Topics

signal transduction

Audio signal processing

digital signal processor

sample signal

Railway signaling

clock signal

continuous signal

distress signal

time signal

Royal Corps of Signals

signals intelligence

In the News (Mon 28 Dec 09)

Northern Trust

Marvin Harrison

Peter Chernin

Gary Locke

Match Play

Penelope Cruz

Mickey Rourke

AR Rahman

Danny Boyle

Hugh Jackman

	Signal transduction
		In biology, signal transduction is any process by which a cell converts one kind of signal or stimulus into another.
		The important value for the strength of the signal relayed by the receptor is the concentration of the hormone-receptor complex, which is defined by the affinity of the hormone for the receptor, the concentration of the hormone and, of course, the concentration of the receptor.
		Signal transduction of transmembrane receptors that are ion channels
	encyclopedia.codeboy.net /wikipedia/s/si/signal_transduction.html (3089 words)

	Signal Transduction-- Biotechnology Stocks (Site not responding. Last check: 2007-11-01)
		signalling cascade" or "second messenger pathway" and the result is that a small stimulus elicits a large response.
		Signal transduction usually involves the binding of "extracellular" signaling molecules to receptors that face outwards from the membrane and trigger events inside.
		Juxtacrine signals are transmitted along cell membranes via protein or lipid components integral to the membrane and are capable of affecting either the emitting cell or cells immediately adjacent.
	www.pipelinedrugs.com /biotechnology_encyclopedia/signal_transduction.htm (2490 words)

	PSORT Users' Manual
		The signal sequence of lipoproteins, i.e., proteins with a covalently attached lipid molecule in their mature N-terminus, are essentially the same as those of usual proteins except the region around their cleavage sites.
		PSORT postulates that the proteins with N-terminal signal sequence will be transported to the cell surface by default unless they have any other signals for specific retention or commitment; a luminal protein will be secreted constitutively to the extracellular space and a membrane protein will reside at the plasma membrane.
		The retention signal of ER luminal proteins from the bulk flow is the existence of the sequence motif KDEL in the C-terminus.
	psort.nibb.ac.jp /helpwww.html (3551 words)

	Ribosomes on the Rough endoplasmic reticulum
		This is to allow the interaction of the signal sequence with a complex on the rough endoplasmic reticulum.
		Once the signal sequence is detected, protein synthesis resumes and the rest of the protein is inserted in the lumen.
		Note that a signal peptidase near the inner surface of the membrane works to cleave the signal sequence from the growing peptide.
	cellbio.utmb.edu /cellbio/rer2.htm (1158 words)

	MalSig - Malaria Signal Sequence Predictions
		Sequences should begin with M. As the aim of this program is to predict classical and non-canonical secretory signals at or near the N-terminus of a protein it is important that the N-terminal region of the protein sequence is present.
		The protein sequences are sent externally to these sites and cleavage sites (or in the case of PlasmoAP apicoplast target peptide predictions) are returned for each sequence and displayed in a table alongside fuzzy predictions.
		When a protein sequence is entered the program first generates a hydrophobicity plot and uses this to calculate values for where the hydrophobic region starts, its length, and the maximum value of hydrophobicity in the region.
	bioserve.latrobe.edu.au /cgi-bin/pfsigseq_help.py (736 words)

	Exercise 2: Neural Network Prediction of Signal Peptides
		These are short, N-terminal amino acid sequences that cause a protein to be exported out of the cell and that are usually cleaved off after the protein has been transported across the membrane.
		Signal peptides are not generally homologous, but instead have a number of common properties that are recognized by the secretion system.
		Generally signal peptides are shorter than this, and in fact submitting longer sequences may sometimes lead to false positive predictions.
	www.cbs.dtu.dk /dtucourse/cookbooks/gorm/msc.5.sigpep/signalp.php (1380 words)

	Pfam 20.0 : SPC12 (Site not responding. Last check: 2007-11-01)
		Subsequently, signal recognition particle interacts with its membrane receptor and the ribosome-bound nascent chain is targeted to the ER where it is transferred into a protein-conducting channel.
		The signal sequence of most secretory and membrane proteins is cleaved off at this stage.
		The signal peptidase complex is possibly also involved in proteolytic events in the ER membrane other than the processing of the signal sequence, for example the further digestion of the cleaved signal peptide or the degradation of membrane proteins.
	pfam.wustl.edu /cgi-bin/getdesc?name=SPC12 (385 words)

	Protein Kinesis
		The signal sequence consists of the first portion of the elongating polypeptide chain (so the signal sequence occurs at the amino terminal of the polypeptide).
		the signal sequence is usually clipped off the polypeptide unless the polypeptide is to be retained as an integral membrane protein.
		They are targeted to the nucleus by their nuclear localization sequence, a sequence of 7 - 41 amino acids of which the basic amino acids lysine and arginine are characteristic members.
	home.comcast.net /~john.kimball1/BiologyPages/P/ProteinKinesis.html (992 words)

	Untitled Document (Site not responding. Last check: 2007-11-01)
		However, proteins that will finish their synthesis on the RER have a sequence of amino acids called the signal sequence because this series of amino acids acts as a signal.
		Signal sequences are specific sequences of amino acids of a newly forming (nascent) polypeptide chain.
		The nascent seqence of the secretory protein is a signal sequence but the nascent polypeptide of the glycolytic enzyme is not a signal sequence
	academic.brooklyn.cuny.edu /biology/bio4fv/page/signals.htm (131 words)

	Mutagenesis of the Signal Sequence of Yellow Fever Virus prM Protein: Enhancement of Signalase Cleavage In Vitro Is ...
		Effect of the VPQAQA mutation in the signal sequence of prM on the efficiency of cleavage of prM in cell-free and transient expression assays.
		is inhibited by the VPQAQA mutation in the signal sequence of
		Signal peptidase cleavage at the flavivirus C-prM junction: dependence on the viral NS2B-3 protease for efficient processing requires determinants in C, the signal peptide, and prM.
	jvi.asm.org /cgi/content/full/74/1/24 (7101 words)

	biology - Signal transduction
		In such cases the chain of steps is referred to as a "signalling cascade " or "second messenger pathway" and the result is that a small stimulus elicits a large response.
		Several "signaling molecules", such as the neurotransmitters that allow nerve cells to communicate across synapses, bind to receptor proteins in the membrane and open their ion channels.
		Endocrine signals are produced by endocrine cells and travel through the blood to reach all parts of the body.
	www.biologydaily.com /biology/Signal_transduction (3026 words)

	UWB Radio \| RF Design - direct-sequence UWB signal generation, UWB radio
		The transition from discrete spectral lines to a “continuous” spectrum display is due to the ratio of measurement span (bandwidth of the signal) and the resolution filter of the spectrum analyzer.
		By considering the pulsed signal as BPSK and entering a symbol period that matches the clock frequency of the baseband signal, even the frequency error can be measured.
		Therefore, the exact spectral shape of the test signal is not as significant for sensitivity testing as it would be if the source had to meet the transmitter test mask.
	rfdesign.com /mag/radio_directsequence_uwb_signal/index.html (3530 words)

	Characterization of an Unusual, Sequence-specific Termination Signal for T7 RNA Polymerase -- He et al. 273 (30): 18802 ...
		Two types of signals are known to cause pausing and/or termination by T7 RNAP (7, 8).
		PTH signal was in the NT strand of the heteroduplex (lane 4).
		Failure to terminate at the PTH signal under these circumstances might be due either to failure of the RNAP to interact with elements in the free RNA product (due to its hybridization with the T strand) or failure to reconstitute the PTH signal into duplex DNA.
	www.jbc.org /cgi/content/full/273/30/18802 (7162 words)

	Input (Site not responding. Last check: 2007-11-01)
		A state, or a sequence of states, of a point that accepts data.
		A stimulus, such as a signal or interference, that enters a functional unit, such as a telecommunications system, a computer, or a computer program.
		In control theory, the inputs of a system are the signals that can be observed or affected that feed into the system.
	www.freedownloadsoft.com /info/input.html (169 words)

	The signal peptide sequence of a lytic transglycosylase of Neisseria meningitidis is involved in regulation of gene ...
		The signal peptide sequence of a lytic transglycosylase of Neisseria meningitidis is involved in regulation of gene expression -- Serruto and Galeotti 150 (5): 1427 -- Microbiology
		The signal peptide sequence of a lytic transglycosylase of Neisseria meningitidis is involved in regulation of gene expression
		The 60 nucleotides encoding the signal peptide of the Neisseria
	mic.sgmjournals.org /cgi/content/full/150/5/1427 (5331 words)

	Many random sequences functionally replace the secretion signal sequence of yeast invertase -- Kaiser et al. 235 ...
		In the process of protein secretion, amino-terminal signal sequences are key recognition elements; however, the relation between the primary sequence of an amino-terminal peptide and its ability to function as an export signal remains obscure.
		The limits of variation permitted for functional signal sequences were determined by replacement of the normal signal sequence of Saccharomyces cerevisiae invertase with essentially random peptide sequences.
		Since about one-fifth of these sequences can function as an export signal the specificity with which signal sequences are recognized must be very low.
	www.sciencemag.org /cgi/content/abstract/235/4786/312 (665 words)

	A Novel Class of secA Alleles That Exert a Signal-Sequence-Dependent Effect on Protein Export in Escherichia coli -- ...
		Signal sequences are composed of three domains: a positively
		Effect of the secA alleles on MalE export, determined by the efficiency of signal sequence cleavage.
		Effect of the secA alleles on wild-type preprotein export, determined by the efficiency of signal sequence cleavage.
	www.genetics.org /cgi/content/full/162/3/1031 (6779 words)

	Mutational analysis of the variant surface glycoprotein GPI-anchor signal sequence in Trypanosoma brucei -- Böhme ...
		Mutational analyses of the C-terminal GPI signal sequences
		Furukawa, Y., Tsukamoto, K. and Ikezawa, H. Mutational analysis of the C-terminal signal peptide of bovine liver 5'-nucleotidase for GPI anchoring: a study on the significance of the hydrophilic spacer region.
		Fusion of sequence elements from non-anchored proteins to generate a fully functional signal for glycophosphatidylinositol membrane anchor attachment.
	jcs.biologists.org /cgi/content/full/115/4/805 (6301 words)

	Signal-sequence-independent secretion of the staphylococcal nuclease in Mycobacterium smegmatis -- Recchi et al. 148 ...
		Signal sequences were searched using the signal IP server at
		a canonical signal sequence was predicted using the signal IP server in only 20% of the cases.
		As for the TAT pathway, the nuclease is devoid of signal peptide
	mic.sgmjournals.org /cgi/content/full/148/2/529 (3927 words)

	A Signal Sequence Is Sufficient for Green Fluorescent Protein to Be Routed to Regulated Secretory Granules -- El ...
		A Signal Sequence Is Sufficient for Green Fluorescent Protein to Be Routed to Regulated Secretory Granules -- El Meskini et al.
		A Signal Sequence Is Sufficient for Green Fluorescent Protein to Be Routed to Regulated Secretory Granules
		sequence, the globin was rapidly destroyed in the ER (41).
	endo.endojournals.org /cgi/content/full/142/2/864 (5789 words)

	Apoptosis-inducing signal sequence mutation in carbonic anhydrase IV identified in patients with the RP17 form of ...
		Apoptosis-inducing signal sequence mutation in carbonic anhydrase IV identified in patients with the RP17 form of retinitis pigmentosa -- Rebello et al.
		sequence variant is predicted not to alter the sequence of the
		in the primary sequence of the mature proteins, not in the signal
	www.pnas.org /cgi/content/full/101/17/6617 (4519 words)

	Viral Preprotoxin Signal Sequence Allows Efficient Secretion of Green Fluorescent Protein by Candida glabrata, Pichia ...
		sequence is excised by the action of the late Golgi endopeptidase
		Internal cleavage sites of the ER lumenal signal peptidase (SP) and of the late Golgi endopeptidase Kex2p are indicated.
		Sequence of the M28 dsRNA: preprotoxin is processed to an
	aem.asm.org /cgi/content/full/70/2/961 (3308 words)

	SignalP 3.0 Server
		The method incorporates a prediction of cleavage sites and a signal peptide/non-signal peptide prediction based on a combination of several artificial neural networks and hidden Markov models.
		The sequences are kept confidential and will be deleted after processing.
		Prediction of signal peptides and signal anchors by a hidden Markov model.
	www.cbs.dtu.dk /services/SignalP (266 words)

	The DsbA Signal Sequence Directs Efficient, Cotranslational Export of Passenger Proteins to the Escherichia coli ...
		The DsbA Signal Sequence Directs Efficient, Cotranslational Export of Passenger Proteins to the Escherichia coli Periplasm via the Signal Recognition Particle Pathway -- Schierle et al.
		The DsbA Signal Sequence Directs Efficient, Cotranslational Export of Passenger Proteins to the Escherichia coli Periplasm via the Signal Recognition Particle Pathway
		mode of MBP export when the native signal sequence is utilized.
	jb.asm.org /cgi/content/abstract/185/19/5706 (511 words)

	Role of Signal Sequence in Vaccine-Induced Protection against Experimental Coccidioidomycosis -- Jiang et al. 70 (7): ...
		Role of Signal Sequence in Vaccine-Induced Protection against Experimental Coccidioidomycosis -- Jiang et al.
		The vaccine efficacy of the gene sequence encoding the signal
		level than the signal sequence or the full-length Ag2 gene.
	iai.asm.org /cgi/content/abstract/70/7/3539 (490 words)

	Medical Dictionary: Protein signal sequence - WrongDiagnosis.com
		Protein signal sequence : N\-terminal, hydrophobic sequences which mediate the attachment of newly translated polypeptide chains to intracellular membranes; in some membrane proteins the signal peptide remains as a permanent anchor, while in secretory proteins it is cleaved.
		The term Protein signal sequence can be used for:
		The description of Protein signal sequence may also be used for the following terms:
	www.wrongdiagnosis.com /medical/protein_signal_sequence.htm (174 words)

	Sequence of human asialoglycoprotein receptor cDNA. An internal signal sequence for membrane insertion -- Spiess et al. ...
		An internal signal sequence for membrane insertion -- Spiess et al.
		residues is very homologous to the sequence of the major asialoglycoprotein
		The amino-acid sequence of the abalone (Haliotis laevigata) nacre protein perlucin: Detection of a functional C-type lectin domain with galactose/mannose specificity
	www.jbc.org /cgi/lookup?vol=260&fp=1979&view=abstract (703 words)

	Brinkman Lab: Links
		DNA and protein sequence databases, analysis and reference
		Vecscreen - NCBI's BLAST detection of vector sequences
		NCBI's Glossary of Terms - primarily relevant to BLAST sequence analysis
	www.pathogenomics.sfu.ca /brinkman/links.html (399 words)

	PSORT WWW Server
		It receives the information of an amino acid sequence and its source orgin, e.g., Gram-negative bacteria, as inputs.
		Then, it analyzes the input sequence by applying the stored rules for various sequence features of known protein sorting signals.
		PSORT-B, a program applicable to the sequences of Gram-negative bacteria, is available at the new portal site (www.psort.org) maintained by Fiona Brinkman's laboratory, Simon Fraser U., Canada since July, 2003.
	psort.nibb.ac.jp (425 words)

	Nutritional Supplements Directory - Amino Acid - Amino Acid Sequence
		Computer program to reconstruct phylogenetic trees from molecular sequence data
		Illustrated explanation of the ribosomal protein synthesis by Gwen V. Childs,
		Phylogenetic analyses of DNA or protein sequences using maximum likelihood.
	www.aminoacid.nutritional-supplements-directory.com /aminoacidsequence (156 words)

Try your search on: Qwika (all wikis)