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	Sildenafil - Wikipedia, the free encyclopedia
		Sildenafil is metabolised by hepatic enzymes and excreted by both the liver and kidneys.
		Sildenafil is not scored and it is not advisable to cut it to change dosage since the active compound is not distributed homogenously in the tablet.
		Sildenafil is commonly and increasingly used as an aphrodisiac.
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	Mosby's Drug Consult Top 200
		Sildenafil citrate is a white to off-white crystalline powder with a solubility of 3.5 mg/ml in water and a molecular weight of 666.7.
		Sildenafil citrate should be used with caution in patients with anatomical deformation of the penis (such as angulation, cavernosal fibrosis or Peyronie's disease), or in patients who have conditions which may predispose them to priapism (such as sickle cell anemia, multiple myeloma, or leukemia).
		Sildenafil was negative in in vitro bacterial and Chinese hamster ovary cell assays to detect mutagenicity, and in vitro human lymphocytes and in vivo mouse micronucleus assays to detect clastogenicity.
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	Sildenafil (Viagra): Pulmonary Hypertension Treatment
		Sildenafil (Viagra) has shown promise in treating patients with Primary Pulmonary Hypertension which is caused by a narrowing of the blood vessels in the lungs, leading to high blood pressure in the pulmonary system and heart failure.
		Sildenafil is an inhibitor of PDE 5, a hormone produced by the body that causes blood vessel to constrict.
		Another study contrasting the effects of inhaled iloprost to oral sildenafil in pulmonary hypertension found that while iloprost caused a greater reduction in pulmonary artery pressure, sildenafil was effective for a longer period of time.
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		Sildenafil is used to treat men with erectile dysfunction (also called sexual impotence) because it helps to maintain an erection that is produced when the penis is stroked.
		Sildenafil should not be used by men who are using nitrates such as nitroglycerin (e.g., Nitrostat or Transderm-Nitro) to lower their blood pressure; sildenafil can cause the blood pressure to drop too far.
		Sildenafil has not been studied in combination with other medications that are used in the treatment of erectile dysfunction.
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	Frequently Asked Questions
		Sildenafil Citrate was originally developed by Pfizer®; as a heart medication to improve blood flow by relaxing arteries.
		Sildenafil Citrate increases blood flow to the penis, so that when a man is sexually aroused, he can get and keep an erection.
		Sildenafil Citrate soft tabs are absorbed directly into the blood stream through the cell walls under the tongue, thereby eliminating the necessity to go through the digestive tract.
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	sildenafil (oral)
		Although sildenafil is not indicated for use by women, it is in the FDA pregnancy category B.
		Sildenafil is used as needed, so you are not likely to miss a dose.
		Symptoms of a sildenafil overdose are not known, but are likely to include chest pain, dizziness, an irregular heartbeat, and swelling of the ankles or legs.
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	sildenafil - Mens Health: health and medical information about Mens Health Issues
		Sildenafil also reduces the pressure in the pulmonary artery in a serious condition called pulmonary arterial hypertension.
		PRESCRIBED FOR: Sildenafil is used for the treatment of erectile dysfunction of either organic (medical condition) or psychogenic (psychological) cause and for pulmonary arterial hypertension.
		When sildenafil is taken with a high fat meal, the rate of absorption is reduced, with an average delay in the time to maximal concentration of 1 hour.
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	Focus on Sildenafil - a drug for male impotence
		Sildenafil is manufactured by Pfizer under the trade name Viagra.
		Sildenafil is an inhibitor of type 5 -cGMP phosphodiesterase.
		Sildenafil is well absorbed and reaches its maximum plasma levels an hour after ingestion.
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	Sildenafil citrate
		Although not approved for use in women, clinical studies have shown that sildenafil citrate may be effective in relieving female sexual dysfunction for some women.
		Sildenafil citrate was originally developed in 1991 as a treatment for angina, or chest pain.
		Double-blind, randomized clinical trials of sildenafil citrate have shown that the drug has an 63-82% efficacy rate in improving erectile activity among men with ED, depending on the dose administered (between 25 and 100 mg), compared to a 24% improvement in men receiving a placebo.
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		Sildenafil (Viagra®;) is used to treat erectile dysfunction (impotence) in men. It can help many men who have erectile dysfunction to keep an erection upon sexual excitement (stimulation). Taking sildenafil will not automatically cause an erection. ; Men who take it must be sexually stimulated for an effect to occur.
		Sildenafil is only for patients with erectile dysfunction. It is not for use in newborns, children, or women.
		Erectile dysfunction is not cured by sildenafil. It is a treatment for this condition.
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	MedlinePlus Drug Information: Sildenafil
		Sildenafil is used to treat erectile dysfunction (impotence; inability to get or keep an erection) in men.
		Sildenafil is in a class of medications called phosphodiesterase (PDE) inhibitors.
		Sildenafil does not prevent pregnancy or the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV).
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	Sildenafil Drug Information
		Sildenafil is also used to treat the symptoms of pulmonary arterial hypertension.
		Sildenafil helps by increasing the supply of blood to the lungs and reducing the workload of the heart.
		Sildenafil is not indicated for use in women for erectile dysfunction.
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