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Topic: Sildenafil citrate


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In the News (Thu 17 Dec 09)

  
  Sildenafil - Wikipedia, the free encyclopedia
Sildenafil citrate, sold under the names Viagra, Revatio and (in the Indian subcontinent at least) Caverta, is a drug used to treat male erectile dysfunction (impotence) and pulmonary arterial hypertension (PAH), developed by the pharmaceutical company Pfizer.
Sildenafil is a potent and selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum.
Sildenafil is metabolised by hepatic enzymes and excreted by both the liver and kidneys.
en.wikipedia.org /wiki/Sildenafil   (1163 words)

  
 Viagra Side Effects, and Drug Interactions - Sildenafil Citrate - RxList Monographs
The AUC of the active metabolite, N-desmethyl sildenafil, was increased 62% by loop and potassium-sparing diuretics and 102% by nonspecific beta-blockers.
Sildenafil citrate (50 mg) did not potentiate the hypotensive effect of alcohol in healthy volunteers with mean maximum blood alcohol levels of 0.08%.
Sildenafil (100 mg) did not affect the steady state pharmacokinetics of the HIV protease inhibitors, saquinavir and ritonavir, both of which are CYP3A4 substrates.
www.rxlist.com /cgi/generic/viagra_ad.htm   (1224 words)

  
 Sildenafil Citrate - Viagra   (Site not responding. Last check: 2007-10-09)
Sildenafil citrate increases the body's ability to achieve and maintain an erection during sexual stimulation.
Sildenafil citrate should not be taken by women, but it is not expected to be harmful to an unborn baby.
The symptoms of an overdose of Sildenafil citrate are not known, but they are likely to include chest pain, dizziness, an irregular heartbeat, and swelling of the ankles or legs.
sildenafil.opkgroup.com   (532 words)

  
 - SILDENAFIL CITRATE
Sildenafil citrate is prescribed to treat male sexual impotence also known as ED (erectile dysfunction).
Sildenafil citrate works by controlling the enzyme phosphodiesterase TYPE 5(PDE5), which in turn causes higher level of Nitric oxide that dilates blood vessels in the male organ by allowing the influx of blood needed to sustain an erection.
Sildenafil citrate is effective in about 70% of men, though it is effective only when poor blood circulation is the cause of the ED.
www.themedicine.net /drugs/sildenafil-citrate.html   (589 words)

  
 Sildenafil Citrate   (Site not responding. Last check: 2007-10-09)
Sildenafil, the first drug in a new class of medications, works by increasing the blood flow to the penis necessary for establishing and maintaining an erection.
Sildenafil should be taken only by men who have been clinically evaluated for and diagnosed with erectile dysfunction by a doctor.
Sildenafil can enhance the action of nitrates (such as nitroglycerin, which is used to treat episodes of angina), causing potentially dangerous decreases in blood pressure.
www.wholehealthmd.com /refshelf/drugs_view/0,1524,829,00.html   (661 words)

  
 anglopharmacy.com - Sildenafil Citrate - FAQs   (Site not responding. Last check: 2007-10-09)
Sildenafil Citrate since it increases blood flow to the penis, if a man becomes sexually aroused, he should be able to get and maintain an erection.
Sildenafil Citrate had been proven to improve the erections of up to 4 out of 5 men which is compared to 1 out of 4 who took a placebo pill.
Sildenafil Citrate has been seen to be effective in as little as half an hour and can stay effective for up to 4 hours.
www.anglopharmacy.com /viagra/viagra_faq.html   (1441 words)

  
 Sildenafil Citrate ( Silagra - Viagra ) Clinical Studies
Sildenafil is only about 10-fold potent for PDE5 compared to PDE6, an enzyme found in the retina; this lower selectivity is thought to be the basis for abnormalities related to colour vision observed with higher doses or plasma levels.
The AUC of the active metabolite, N-desmethyly sildenafil, was increased 62% by loop and potassium-sparing diurectics and 102% by non-specific beta-blockers.
Sildenafil was negative in vitro bacterial and Chinese hamster ovary cell assays to detect mutagenicity, and in vitro human lymphocytes and in vivo mouse micronucleus assays to detect clastogenicity.
www.silagra.info /sildenafil.html   (1621 words)

  
 Viagra Clinical Pharmacology - Sildenafil Citrate - USA Today   (Site not responding. Last check: 2007-10-09)
Sildenafil is only about 10-fold as potent for PDE5 compared to PDE6, an enzyme found in the retina which is involved in the phototransduction pathway of the retina.
The inhibition of PDE5 in these tissues by sildenafil may be the basis for the enhanced platelet antiaggregatory activity of nitric oxide observed in vitro, an inhibition of platelet thrombus formation in vivo and peripheral arterial-venous dilatation in vivo.
After either oral or intravenous administration, sildenafil is excreted as metabolites predominantly in the feces (approximately 80% of administered oral dose) and to a lesser extent in the urine (approximately 13% of the administered oral dose).
www.healthscout.com /rxdetail/68/91/5/main.html   (2549 words)

  
 Sildenafil Citrate
Generic Sildenafil Citrate is the active ingredient used to treat erectile dysfunction (impotence) in men.
Sildenafil has no direct relaxant effect on isolated human corpus cavernosum, but enhances the effect of nitric oxide (NO) by inhibiting phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum.
Sildenafil is only about 10-fold as potent for PDE5 compared to PDE6, an enzyme found in the retina; this lower selectivity is thought to be the basis for abnormalities related to color vision observed with higher doses or plasma levels (see Pharmacodynamics).
www.cheap-caverta.com /sildenafil.html   (599 words)

  
 Vidrin - New (sildenafil citrate) soft tabs
Sildenafil Citrate, the key ingredient in Viagra®, was originally developed by Pfizer®; as a heart medication.
Sildenafil Citrate increases blood flow to the penis, so that when a man is sexually aroused, he can get and keep an erection.
Conversely, Sildenafil Citrate soft tabs are absorbed directly into the blood stream through the cell walls under the tongue, thereby eliminating the digestive tract, yielding results in about 15 minutes.
www.vidrin.biz /medication/about-vidrin.html   (943 words)

  
 Sildenafil Citrate   (Site not responding. Last check: 2007-10-09)
Although Sildenafil Citrate is not indicated for use by women, it is in the FDA pregnancy category B. This means that sildenafil citrate is not expected to be harmful to an unborn baby.
Sildenafil Citrate is used as needed, so you are not likely to miss a dose.
Symptoms of a Sildenafil Citrate overdose are not known, but are likely to include chest pain, dizziness, an irregular heartbeat, and swelling of the ankles or legs.
www.tadalafil.ca /sildenafil-citrate.htm   (1165 words)

  
 Sildenafil citrate sold under the   (Site not responding. Last check: 2007-10-09)
Sildenafil citrate, sold under the names Viagra, Revatio and (in the Indian subcontinent at least) Caverta, is a drug used to treat male erectile...
Sildenafil citrate, sold under the name Viagra, is a drug used to treat male erectile dysfunction (impotence), developed by the pharmaceutical company...
Sildenafil citrate is currently commonly known by the brand name.
sildenafilcitrateonline.searchear.biz /sildenafil-citrate-sold-under-the.html   (215 words)

  
 body
Sildenafil citrate is a specific phosphodiesterase type 5 (PDE5) enzyme inhibitor, which is predominately localized to the corpus cavernous.
Sildenafil citrate is clearly not an effective treatment for all sexual dysfunctions or effects of aging.
Sildenafil citrate has a half-life of approximately four hours (Morales, Gingell, Collins, Wicker, and Osterloh, 1998), so it is somewhat surprising to see a pronounced effect the next day (12-24 hours later).
www.ejhs.org /volume4/Moser/body.htm   (1799 words)

  
 Viagra / Sildenafil Citrate Facts and Information   (Site not responding. Last check: 2007-10-09)
Sildenafil Citrate (Viagra) was originally developed as a medicine in the cardio vascular to improve blood flow by relaxing the arteries.
Sildenafil Citrate is absorbed into the bloodstreams usually within 60 minutes of ingestion and then acts as an inhibitor to an enzyme called phosphodiesterase - type PDE5, found primarily in the penis.
Viagra / Sildenafil Citrate 100mg extra strength tablets may be cut in half, this is a more cost effective way to achieve a 50mg dosage.
pages.zdnet.com /health/viagra/id1.html   (407 words)

  
 Sildenafil Citrate (Viagra)
Sildenafil citrate is the active ingredient used to treat erectile dysfunction (impotence) in men.
Sildenafil citrate treats erectile dysfunction, the inability to achieve and/or maintain an erection of the penis that is adequate for sexual intercourse.
Sildenafil is a selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum.
www.greatvistachemicals.com /pharmaceuticals/sildenafil-citrate-viagra.html   (551 words)

  
 sildenafil citrate   (Site not responding. Last check: 2007-10-09)
Sildenafil (sil-DEN-a-fil) belongs to a group of medicines that delay the enzymes called phosphodiesterases from working too quickly.
Sildenafil is used to treat men who have erectile dysfunction (also called sexual impotence).
By controlling the enzyme phosphodiesterase, sildenafil helps to maintain an erection that is produced when the penis is stroked.
www.4viagra.org /sildenafil-citrate   (320 words)

  
 Introducing Sildenafil Citrate Soft Tabs!
Introducing Sildenafil Citrate soft tabs, the new sublingual lozenge compounded by a regulated and licensed pharmacy facility from Pfizer’s FDA approved Viagra®.
Sildenafil Citrate soft tabs dissolve under the tongue and enter into the bloodstream within approximately 15 minutes.
Sildenafil Citrate soft tabs are compounded by licensed pharmacists with REAL FDA Approved Viagra®, and are perfectly safe.
buy-sildenafil-citrate-online.com   (145 words)

  
 Zenegra (Sildenafil Citrate)   (Site not responding. Last check: 2007-10-09)
Sildenafil is used a treatment for men experiencing erectile dysfunction (difficulty maintaining an erection).
Sildenafil's mission is to work on enzymes of the body called phosphodiesterases and to improve a man's response to sexual stimulation.
Sildenafil works to control the enzyme, and by doing so regulates the blood flow out of the penis and thereby helping the patient maintain an erection.
www.zenegra-now.com   (126 words)

  
 Sildenafil citrate
Although not approved for use in women, clinical studies have shown that sildenafil citrate may be effective in relieving female sexual dysfunction for some women.
Sildenafil citrate was originally developed in 1991 as a treatment for angina, or chest pain.
Double-blind, randomized clinical trials of sildenafil citrate have shown that the drug has an 63-82% efficacy rate in improving erectile activity among men with ED, depending on the dose administered (between 25 and 100 mg), compared to a 24% improvement in men receiving a placebo.
www.healthatoz.com /healthatoz/Atoz/ency/sildenafil_citrate.jsp   (2634 words)

  
 Viagra Online, Description, Chemistry, Ingredients - Sildenafil Citrate - RxList Monographs
Sildenafil citrate is designated chemically as 1-[[3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin- 5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate.
Sildenafil citrate is a white to off-white crystalline powder with a solubility of 3.5 mg/ml in water and a molecular weight of 666.7.
In addition to the active ingredient, sildenafil citrate, each tablet contains the following inactive ingredients: microcrystalline cellulose, anhydrous dibasic calcium phosphate, croscarmellose sodium, magnesium stearate, hydroxypropyl methylcellulose, titanium dioxide, lactose, triacetin, and FDandC blue #2 aluminum lake.
www.rxlist.com /cgi/generic/viagra.htm   (159 words)

  
 GET BLUE TABS! Viagra soft tabs, Sildenafil Citrate   (Site not responding. Last check: 2007-10-09)
Sildenafil Citrate soft tabs are compounded using Pfizer’s Viagra®.
Sildenafil Citrate soft tabs dissolves under your tongue and enters your system quicker than tablets.
Sildenafil Citrate soft tabs are not affected by food intake..
www.getbluetabs.com   (287 words)

  
 Zenegra :: Sildenafil Citrate :: Generic Sildenafil Citrate   (Site not responding. Last check: 2007-10-09)
Although Zenegra (Sildenafil Citrate) is not indicated for use by women, it is in the FDA pregnancy category B. This means that Zenegra (Sildenafil Citrate) is not expected to be harmful to an unborn baby.
Zenegra (Sildenafil Citrate) is used as needed, so you are not likely to miss a dose.
Symptoms of a Zenegra (Sildenafil Citrate) overdose are not known, but are likely to include chest pain, dizziness, an irregular heartbeat, and swelling of the ankles or legs.
www.zenegra.ca   (1162 words)

  
 sildenafil drug information, sildenafil side effects
Sildenafil citrate is a white to off-white crystalline powder with a solubility of 3.5 mg/ml in water...
Sildenafil citrate, sold under the names Viagra, Revatio and (in the Indian subcontinent at least) Caverta, is a drug...
Sildenafil is a drug used to treat erectile dysfunction (ED), commonly known as impotence, in men.
www.drugs.com /drug/sildenafil   (497 words)

  
 Sildenafil Citrate Opinions   (Site not responding. Last check: 2007-10-09)
Sildenafil Citrate Opinions.The only difference between brand name drugs and generic drugs is that generics are always much less expensive.
Sildenafil Citrate Opinions.Generic drugs are just as safe and effective as their brand-name counterparts.Our products and the name brand equivalents are identical and your body won't know the difference.
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www.benway-uk.com /sildenafil-citrate/Sildenafil-Citrate-Opinions.html   (1262 words)

  
 About sildenafil citrate 100mg   (Site not responding. Last check: 2007-10-09)
Sildenafil Citrate belongs to a group of medicines that delay the enzymes called phosphodiesterases from working too quickly.
Sildenafil Citrate is used to treat men who have erectile dysfunction (also called sexual impotence).
By controlling the enzyme phosphodiesterase, Sildenafil Citrate helps to maintain an erection that is produced when the penis is stroked.
www.generic-viagra-information.com /sildenafil_citrate.htm   (375 words)

  
 purchase sildenafil citrate   (Site not responding. Last check: 2007-10-09)
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 Zenegra Sildenafil Citrate   (Site not responding. Last check: 2007-10-09)
Zenegra Sildenafil Citrate is taken by mouth as needed 45min before sexual activity.
Before using Zenegra Sildenafil Citrate, tell your doctor your medical history, including any allergies (especially drug allergies), any penis conditions such as fibrosis/scarring, history of painful/prolonged erection (priapism), sickle cell anemia, blood system cancers (such as leukemia or myeloma), or Peyronie's disease, eye problems (retina diseases).
Store Zenegra Sildenafil Citrate at room temperature between 59 and 86 degrees F (15-30 degrees C) away from light and moisture.
www.zenegra-sildenafil-citrate.com   (430 words)

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