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Topic: Simian immunodeficiency virus

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	Simian immunodeficiency virus - Biocrawler (Site not responding. Last check: 2007-10-03)
		Simian immunodeficiency virus (SIV) is a retrovirus that is found, in numerous strains, in primates; the strains infecting humans are HIV-1 and HIV-2, the viruses that cause AIDS.
		SIV monkey strains are transmitted sexually and usually do not cause disease in their natural hosts.
		For example, SIV-agm, the SIV strain from African Green Monkeys, causes SAIDS in Rhesus Macaques (the latter are native to Asia and don't carry their own strain of SIV).
	www.biocrawler.com /encyclopedia/SIV (465 words)

	Information about the Simian Immunodeficiency Virus
		CONTEXT: Poliovirus vaccine contaminated with live simian virus 40 (SV40), a macaque polyomavirus that is tumorigenic in rodents, was used extensively in the United States between 1955 and 1963.
		The virus strains had to be potent enough to cause immunity when ingested, but not so strong as to return to virulence after undergoing Pasteur's method of repeatedly infecting laboratory animals and harvesting the weakened viruses.
		This virus was found to produce a latent infection in monkey kidneys and had a cancer-causing potential, as indicated by its ability to produce tumors in laboratory animals.
	www.hepatitis-c.de /siv.htm (7268 words)

	Primate Info Net: Simian Immunodeficiency Virus
		Simian immunodeficiency viruses (SIVs) are lentiviruses that cause acquired immunodeficiency syndrome (AlDS)-like illnesses in susceptible macaque monkeys and are used in the study of AIDS (1).
		Detection of occult simian immunodeficiency virus SIVsmm infection in asymptomatic seronegative nonhuman primates and evidence for variation in SIV gag sequence between in vivo- and in vitro-propagated virus.
		Simian immunodeficiency virus infection of macaques: end-stage disease is characterized by widespread distribution of proviral DNA in tissues.
	pin.primate.wisc.edu /research/biosafety/mmwr.html (1577 words)

	Simian immunodeficiency virus - Wikipedia, the free encyclopedia
		Simian immunodeficiency virus (SIV) is a retrovirus that is found, in numerous strains, in primates; the specific strains infecting humans are HIV-1 and HIV-2, the viruses that cause AIDS.
		SIV monkey strains are transmitted sexually and usually do not cause AIDS in their natural hosts, SMs and African Green Monkeys(AGMs).
		Evidence in favor of this paradigm is that the very mild immune response that AGMs and SMs mount against SIV closely mirrors the maternal immune response to the developing eutherian.
	en.wikipedia.org /wiki/Simian_Immunodeficiency_Virus (661 words)

	Macrophage tropism of simian immunodeficiency virus.
		Simian immunodeficiency virus (SIV) is the causative agent of a disease in rhesus macaques which closely parallels acquired immunodeficiency syndrome (AIDS) in humans infected with human immunodeficiency virus (HIV).
		Several biological and genetic similarities of SIV and HIV indicate that the SIV/macaque system is a useful animal model for HIV infection of humans and AIDS.
		The SIV system may be utilized to develop vaccines and antiviral therapies, to study the origin and evolution of primate lentiviruses, and to study mechanisms of viral pathogenesis.
	www.aegis.com /aidsline/1993/feb/M9320872.html (672 words)

	Perspectives in Disease Prevention and Health Promotion Guidelines to Prevent Simian Immunodeficiency Virus Infection ...
		Simian immunodeficiency virus (SIV) belongs to the family Retroviridae (subfamily Lentivirinae) and is closely related to human immunodeficiency virus types 1 and 2 (HIV-1 and HIV-2), the etiologic agents of acquired immunodeficiency syndrome (AIDS).
		In the laboratory, SIV must be presumed to be present in all SIV cultures, in all materials derived from such cultures, in all specimens from SIV antibody-positive nonhuman primates, and in/on all equipment and devices coming in contact with these materials.
		During the propagation of SIV in the research laboratory, manipulation of concentrated virus preparations or conduct of procedures that may produce aerosols or droplets should be performed in a BSL 2 facility, with additional practices and containment equipment recommended for BSL 3 (17).
	www.cdc.gov /mmwr/preview/mmwrhtml/00001303.htm (2997 words)

	FRISC > Faculty Profiles > Donald Sodora, Ph.D.
		Pathogenicity of simian-human immunodeficiency virus SHIV-89.6P and SIVmac is attenuated in cynomolgus macaques and associated with early T-lymphocyte responses.
		Immunodeficiency in the absence of high viral load in pig-tailed macaques infected with Simian immunodeficiency virus SIVsun or SIVlhoest.
		Chest.Evidence for Vascular Remodeling in the Lungs of Macaques Infected With Simian Immunodeficiency Virus/HIV NEF Recombinant Virus.
	invention.swmed.edu /frisc/faculty/sodora/profile_this_year.shtml (809 words)

	Number 23, The Origin of Simian Immunodeficiency Virus (SIV) Discovered (Site not responding. Last check: 2007-10-03)
		It is now widely acknowledged that the inter-species transmission of SIVcpz virus from chimpanzees to humans has caused the outbreak of the virus in humans, probably because the primates are hunted in the bush and the infected meat is eaten.
		Chimpanzees are actually the only primates in the ape family that are naturally infected and the prevalence of the SIV infection in chimpanzees is weak compared to the prevalence in small monkeys.
		Later in-depth phylogenetic analyses highlighted that the chimpanzee virus (SIVcpz) stems from a recombination of both viruses, the SIVgsn of the greater white-nosed monkey and the SIVrcm of the white-collared mangabay.
	ambafrance-ca.org /HYPERLAB/actualite/archive-US/US-SIV.htm (561 words)

	Simian Immunodeficiency Virus Infections: Simian Immunodeficiency Virus (SIV), Simian Immunodeficiency Disease, ...
		Simian Immunodeficiency Virus Infections: Simian Immunodeficiency Virus (SIV), Simian Immunodeficiency Disease, Simian Lentivirus
		Chakrabarti L, Cumont M-C, Montagnier L and Hurt B. Variable course of primary Simian Immunodeficiency Virus in lymph nodes: Relation to disease progression.
		Lymphadenopathy in Macaques experimentally infected with the Simian immunodeficiency virus (SIV).
	www.vetmed.lsu.edu /biv/SIV-97a.HTM (406 words)

	New Multiple Antigenic Peptide-Based Enzyme Immunoassay for Detection of Simian Immunodeficiency Virus Infection in ... (Site not responding. Last check: 2007-10-03)
		Simian immunodeficiency viruses from multiple lineages infect human macrophages: implications for cross-species transmission.
		Simian immunodeficiency viruses from central and western Africa: evidence for a new species-specific lentivirus in tantalus monkeys.
		Isolation and characterization of a new chimpanzee lentivirus (simian immunodeficiency virus isolate cpz-ant) from a wild-captured chimpanzee.
	jcm.asm.org /cgi/content/full/42/11/5161 (5413 words)

	[No title] (Site not responding. Last check: 2007-10-03)
		Infection of baboons with simian immunodeficiency virus constructed with an HIV-1 Thai subtype E envelope.
		Persistent infection of rhesus macaques with T-cell-line-tropic and macrophage-tropic clones of simian/human immunodeficiency viruses (SHIV).
		Neuropathogenesis of chimeric simian/human immunodeficiency virus infection in pig-tailed and rhesus macaques.
	hiv-web.lanl.gov /content/hiv-db/REVIEWS/KUIKEN2000/Kuiken.html (1666 words)

	Susceptibilities of Simian Immunodeficiency Virus to Protease Inhibitors -- Giuffre et al. 47 (5): 1756 -- ... (Site not responding. Last check: 2007-10-03)
		The SIV protease was inhibited by one preclinical
		An inhibitor of the protease blocks maturation of human and simian immunodeficiency viruses and spread of infection.
		Simian immunodeficiency virus (SIV) infection of infant rhesus macaques as a model to test antiretroviral drug prophylaxis and therapy: oral 3'-azido-3'-deoxythymidine prevents SIV infection.
	aac.asm.org /cgi/content/full/47/5/1756 (2657 words)

	Induction of AIDS in rhesus monkeys by molecularly cloned simian immunodeficiency virus -- Kestler et al. 248 (4959): ... (Site not responding. Last check: 2007-10-03)
		Cell Tropism of Simian Immunodeficiency Virus in Culture Is Not Predictive of in Vivo Tropism or Pathogenesis.
		Expression of Simian Immunodeficiency Virus (SIV) Nef in Astrocytes during Acute and Terminal Infection and Requirement of Nef for Optimal Replication of Neurovirulent SIV In Vitro.
		Neutralizing Antibodies in Sera from Macaques Immunized with Attenuated Simian Immunodeficiency Virus.
	www.sciencemag.org /cgi/content/abstract/248/4959/1109 (3349 words)

	Structure of tat-, rev-, and env- specific transcripts of a cloned simian immunodeficiency virus from rhesus macaques ... (Site not responding. Last check: 2007-10-03)
		Structure of tat-, rev-, and env- specific transcripts of a cloned simian immunodeficiency virus from rhesus macaques (SIVmac1A11).
		School of Medicine, Department of Medical Pathology, University of California, Davis, CA Simian immunodeficiency virus from rhesus macaques (SIVmac) produces an immunosuppressive disease in these animals that is similar to that caused by human immunodeficiency virus (HIV-1), the etiologic agent of acquired immunodeficiency syndrome in humans.
		We are analyzing splicing patterns of specific SIV transcripts to determine factors that regulate viral expression and replication.
	gateway.nlm.nih.gov /MeetingAbstracts/102197588.html (393 words)

	Lack of simian immunodeficiency virus (SIV) specific IgA response in the intestine of SIV infected rhesus macaques -- ... (Site not responding. Last check: 2007-10-03)
		in SIV infected rhesus macaques 0.6 mg/dl (0.3–1.7), and
		Figure 3 Typical example of simian immunodeficiency virus (SIV) specific immunoglobulin isotype in serum and culture supernatants of duodenal biopsy specimens of one SIV infected animal during the time course of infection indicated by dot blot analysis.
		to be an abnormal and paradoxical IgA response in SIV infected
	gut.bmjjournals.com /cgi/content/full/50/5/608 (4457 words)

	Heavy drinking can hasten the progression of the simian immunodeficiency virus disease
		Alcohol abuse is also very common among individuals infected with human immunodeficiency virus (HIV).
		Alcohol abuse is also more common among individuals already infected with human immunodeficiency virus (HIV) than among the population as a whole.
		Bagby noted that although his study implicates alcohol abuse as a cofactor in accelerating SIV disease progression and, by extrapolation, HIV disease — the exact mechanisms by which this occurs remain unclear.
	www.eurekalert.org /pub_releases/2006-09/ace-hdc091706.php (993 words)

	Retrovirology \| Full text \| Seroprevalence of simian immunodeficiency virus in wild and captive born Sykes' monkeys ...
		Seroprevalence of simian immunodeficiency virus in wild and captive born Sykes' monkeys (Cercopithecus mitis) in Kenya
		Evidence of infection by naturally occurring SIVs has been documented in a variety of different non-human African primate species [7-9] and additional types of SIV are likely to exist in other African primates as well [9].
		A virus isolate (SIVsyk173) was made from one SIVsyk infected animal and an infectious clone was produced, sequenced and shown to form a distinct phylogenetic group from other known SIVs [15].
	www.retrovirology.com /content/1/1/34 (4534 words)

	Simian Immunodeficiency Virus (SIV)
		Simian immunodeficiency viruses have been isolated from several species of monkeys.
		Although virus isolation can be used to diagnose SIV infection, a long incubation period is required to obtain results.
		SIV detection by PCR is the most rapid, sensitive and specific method for the diagnosis of this infection.
	www.zoologix.com /primate/Datasheets/SimianImmunodeficiencyVirus.htm (574 words)

	Simian immunodeficiency virus infection in a patas monkey (Erythrocebus patas): evidence for cross-species transmission ...
		Simian immunodeficiency virus infection in a patas monkey (Erythrocebus patas): evidence for cross-species transmission from African green monkeys (Cercopithecus aethiops sabaeus) in the wild -- Bibollet-Ruche et al.
		Simian immunodeficiency virus infection in a patas monkey (Erythrocebus patas): evidence for cross-species transmission from African green monkeys (Cercopithecus aethiops sabaeus) in the wild
		Foci of Endemic Simian Immunodeficiency Virus Infection in Wild-Living Eastern Chimpanzees (Pan troglodytes schweinfurthii)
	vir.sgmjournals.org /cgi/content/abstract/77/4/773 (1478 words)

	Cytotoxic T Lymphocyte Responses to Human Immunodeficiency Virus: Control and Escape -- Sewell et al. 18 (4): 230 -- ... (Site not responding. Last check: 2007-10-03)
		Emergence of CTL coincides with clearance of virus during primary simian immunodeficiency virus infection in rhesus monkeys.
		Longitudinal analysis of human immunodeficiency virus type 1-specific cytotoxic T lymphocyte responses: a predominant gag-specific response is associated with nonprogressive infection.
		Persistent hepatitis C virus infection in a chimpanzee is associated with emergence of a cytotoxic T lymphocyte escape variant.
	stemcells.alphamedpress.org /cgi/content/full/18/4/230 (7256 words)

	Induction of Cell-Cycle Regulators in Simian Immunodeficiency Virus Encephalitis -- Jordan-Sciutto et al. 157 (2): 497 ... (Site not responding. Last check: 2007-10-03)
		in HIVE and simian immunodeficiency virus encephalitis (SIVE)
		Westmoreland SV, Halpern E, Lackner AA: Simian immunodeficiency virus encephalitis in rhesus macaques is associated with rapid disease progression.
		Wiley CA, Achim C: Human immunodeficiency virus encephalitis is the pathological correlate of dementia in acquired immunodeficiency syndrome.
	ajp.amjpathol.org /cgi/content/full/157/2/497 (4946 words)

	Virology Journal \| Full text \| Role of CD8+ cells in controlling replication of nonpathogenic Simian Immunodeficiency ...
		Simian immunodeficiency virus (SIV) infection of macaques has proven useful for modeling HIV disease pathogenesis and intervention strategies [1-3].
		Immediately before virus inoculation, 3 animals were depleted of CD8+ cells via administration of the anti-CD8 antibody cM-T807 at a dose of 50 mg/kg body weight (administered slowly intravenously); the same dose was repeated 3 weeks later.
		This is in contrast to infection with virulent SIV isolates, for which irreversible damage to the immune system appears to occur early during the course of infection [9,30-32].
	www.virologyj.com /content/3/1/22 (2739 words)

	ADARC \| Research Programs
		Genetic characterization of new West African simian immunodeficiency virus SIVsm: geographic clustering of household-derived SIV strains with human immunodeficiency virus type 2 subtypes and genetically diverse viruses from a single feral sooty mangabey troop.
		Marx PA and Chen Z. The function of simian chemokine receptors in the replication of SIV.
		Molecular characterization of human immunodeficiency virus type 1 and hepatitis C virus in paid blood donors and injection drug users in china.
	www.adarc.org /research/chen/pubs.htm (957 words)

	ScienceDaily: Heavy Drinking Can Hasten Progression Of Simian Immunodeficiency Virus Disease (Site not responding. Last check: 2007-10-03)
		Alcohol Researchers Show "Friendly" Virus Slows HIV Cell Growth (September 6, 2001) -- A team of alcohol researchers led by Jack Stapleton, M.D., of the Department of Internal Medicine, University of Iowa College of Medicine and the Iowa City Veterans Affairs Medical Center, report in...
		Alcohol Increases Hepatitis C Virus In Human Cells; Drinking May Compromise Treatment Success (June 27, 2003) -- A team of NIH-supported researchers today report that alcohol increases replication of the hepatitis C virus (HCV) in human cells and, by so doing, may contribute to the rapid course of HCV...
		The dramatic and chilling story of an Ebola virus outbreak in a surburban Washington, D.C. laboratory, with descriptions of frightening historical epidemics of rare and lethal viruses.
	www.sciencedaily.com /releases/2006/09/060924175549.htm (2173 words)

	Genetic analysis of simian immunodeficiency virus expressed in milk and selectively transmitted through breastfeeding. (Site not responding. Last check: 2007-10-03)
		Genetic analysis of simian immunodeficiency virus expressed in milk and selectively transmitted through breastfeeding.
		To develop effective intervention strategies that prevent breast milk transmission of human immunodeficiency virus (HIV), we must understand the specific viral properties and mechanisms responsible for infant infection.
		We have used lactating rhesus macaques infected with a pathogenic simian immunodeficiency virus (SIV) stock to analyze the viral genotypes expressed in plasma and milk throughout the disease course and to identify those variants ultimately transmitted to infants through breastfeeding.
	breastfeeding.researchtoday.net /archive/3/3/228.htm (346 words)

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